Articles tagged with Cardiology
Gracie Greenlaw, an 11-year-old patient with hypoplastic left heart syndrome, undergoes the world's first pediatric heart and liver dual organ transplant at Children's Hospital Colorado. The groundbreaking procedure, performed by Dr. Megan Adams' team, aims to improve her quality of life by addressing long-term complications from her h...
A novel analysis found that financial strain and food insecurity accelerate biological aging and increase mortality risk, surpassing traditional risk factors. The study emphasizes the need for targeted preventive interventions and patient-centered care to address social determinants of health.
Experts warn that nicotine-containing products, including vapes, heated tobacco, and shisha, cause cardiovascular damage regardless of delivery system. The report highlights a rapid rise in youth addiction fueled by flavours and social media marketing.
A new study published in the Canadian Journal of Cardiology suggests that strong and supportive relationships can improve heart health for individuals with cardiovascular disease. The review highlights the need to include intimate partners in cardiac rehabilitation programs to support long-term heart health and quality of life.
A large study found that a family history of cardiometabolic diseases increases the risk of progressive heart damage in adolescents, with increased glucose levels partly explaining this association. The study suggests that early intervention and healthy lifestyle habits can help prevent premature heart damage in children.
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A study found cryopreserved platelets to be a cost-effective option for managing surgical bleeding in cardiac surgery, dominating liquid-stored platelets in this setting. Further investigation is required to assess the economic benefits of cryopreserved platelets in broader populations.
A genetic variant is likely putting some children with myocarditis at higher risk of developing heart failure. The study found that 34.4% of children with dilated cardiomyopathy had a genetic variant, compared to only 6.3% of control children.
Researchers found that sudden cardiac death (SCD) among colorectal cancer patients decreased overall, but disparities remained based on age, sex, and geographic location. The study highlights the need for tailored heart monitoring and care strategies for cancer patients, particularly in underserved groups.
The Society for Cardiovascular Angiography and Interventions (SCAI) reviewed the 2025 Interventional Cardiology Fellowship Match results, noting that nearly all applicants successfully matched but 71 positions remained unfilled. SCAI attributes this to a lack of trainees in the pipeline, citing factors like radiation exposure and burno...
A randomized clinical trial shows that semaglutide improves glycemic control and weight outcomes in individuals with schizophrenia. The study suggests using glucagon-like peptide-1 receptor agonists as an early intervention strategy to reduce cardiometabolic risk in this population.
In-flight cardiac arrest is a rare yet catastrophic event that claims up to 86% of air fatalities. Implementing automated external defibrillators (AEDs) on board could significantly boost survival rates from 6% to up to 70%. The authors recommend standardized CPR protocols training, telemedicine integration, and mandatory AED placement.
Large language models are revolutionizing cardiovascular imaging by automating the interpretation of quantitative perfusion data in nuclear medicine and cardiac magnetic resonance. They also enable personalized protocol optimization in coronary computed tomography angiography, leveraging federated learning for data privacy.
The Society for Cardiovascular Angiography and Interventions (SCAI) and Cardiovascular Research Technologies (CRT) announce a new collaboration to elevate the field of interventional cardiology through shared education programming, legislative activities, and future research initiatives. The partnership aims to improve patient outcomes...
Researchers have identified a key mechanism behind statin-induced muscle damage, paving the way for new statins with reduced side effects. By understanding how statins interact with muscle proteins, scientists can design safer alternatives that preserve cholesterol-lowering benefits.
Withdrawal of tirzepatide after 36-week treatment led to 25% or greater weight regain in most participants within a year, reversing initial cardiometabolic parameter improvements. Continued obesity treatment is crucial for sustained benefits.
A new study found that current cardiac screening tools are not optimal and fail to identify half the people who are at risk of having a heart attack. The researchers assessed the accuracy of widely used tools, including ASCVD and PREVENT calculators, and found that nearly half of patients would not have been recommended for preventive ...
A new AI-driven app, AortaGPT, aims to improve diagnosis and treatment of heritable thoracic aortic diseases by translating complex genetics concepts into actionable care recommendations. The app can also detect subtle facial features associated with genetic conditions affecting the aorta.
The ESC Digital & AI Summit showcases innovations like smartphone stethoscopes, voice-detected heart failure, and blood-spot analysis for early cardiovascular disease detection. Virtual training using 3D-printed and virtual hearts enables hands-on learning of complex cardiac procedures.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
A new report from Northwestern University offers six practical strategies to improve the doctor-patient bedside encounter in an era dominated by AI. By employing these strategies, clinicians can strengthen patient-physician relationships, combat inequities, and reduce burnout, ultimately leading to better patient outcomes.
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
Researchers discovered a threefold reduction in harm among patients with coronary artery stenosis who experience pulmonary embolism. Patients with CAS had lower signs of right ventricular strain, including heart rate and biomarker levels.
A study published in the Chinese Medical Journal identified GSTP1 as a key regulator that blocks JNK-driven ferroptosis, providing protection against DOX-induced cardiomyopathy. Overexpression of GSTP1 inhibited ferroptosis and improved DOX-induced heart injury.
The Family Heart Foundation has launched the Lp(a) AW(a)RE initiative to educate primary care clinicians, healthcare insurance providers, and policymakers about high lipoprotein(a). The program aims to increase awareness, screening, and diagnosis of this genetic risk factor for premature cardiovascular disease.
A new editorial highlights the importance of primary care in preventing heart disease in breast cancer survivors. The study found that most women do not go on to develop serious cardiac disease, but those with higher-risk chemotherapy, older age, or multiple cardiovascular risk factors may benefit from closer monitoring.
Researchers have visualized intricate dynamics of heart cell interaction during repair, revealing how immune cells guide connective tissue and prevent overgrowth of scar tissue. The study provides a critical foundation for future research aimed at reducing scar formation and maintaining the heart's pumping capacity.
A new research project at Goethe University Frankfurt aims to shed light on the molecular pathways of epoxyeicosatrienoic acids (EETs) in cardiovascular diseases. The project will search for transmembrane proteins that bind to EETs and mediate their effects, with potential implications for developing new classes of drugs.
A study found a single mutation in the CD36 gene increases risk of dilated cardiomyopathy by 33% in individuals of African descent. This variant is more common in Black individuals and may account for 20% of excess DCM risk.
The study found that men, Black patients, and those living in low socioeconomic areas were disproportionately affected by the increased amputation rates. The authors emphasize the need for aggressive prevention, early diagnosis, and intensive risk factor management to address the growing burden of diabetes and PAD.
Researchers developed an algorithm to optimize pacemaker function usage, reducing battery power consumption and potentially extending battery life by years. By switching off unnecessary features, doctors can reduce the number of surgeries needed and lower associated costs for the NHS.
Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.
Researchers validate GLIS model as a reliable predictor of sarcopenia and mortality risk in older patients with heart failure, outperforming existing tests. The model's accuracy enables early detection of physical decline and poor prognosis, informing treatment planning and discharge decisions.
Dr. Bruce D. Gelb, a pioneering pediatric cardiologist and geneticist, is honored with the 2026 APS John Howland Award for his groundbreaking research on congenital heart disease and developmental disorders. His work has profoundly shaped our understanding of these conditions and elevated the field of pediatric medicine.
The study found that cutting balloon angioplasty is noninferior to intravascular lithotripsy in treating calcified coronary artery disease. The procedure is also less costly, making it a reasonable strategy for managing significantly calcified lesions.
A large international study found that utilizing sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine DES implantation for treating de novo coronary artery disease. The results showed comparable outcomes, including low rates of cardiac death and target vessel myocardial infarction.
A new study published in TCT 2025 reveals that at least 4.7 million people aged 65-85 living in the US have moderate or greater valvular heart disease (VHD), and at least 10.6 million have clinically significant VHD. The prevalence of VHD increases with advanced age, highlighting the need for screening and treatment programs.
Dr. Hani K. Najm, a world-renowned congenital cardiothoracic surgeon, has been named the next vice president of the American College of Cardiology. He will assume his role during ACC.26 and is committed to advancing heart health for all, building on the organization's mission to optimize patient care and outcomes.
The ENCIRCLE trial found that the SAPIEN M3 system significantly reduced mitral regurgitation severity, improved heart failure symptoms, and quality of life for patients with severe mitral regurgitation. Over 95% of patients had little-to-no valve leakage at one year.
A new sirolimus-eluting balloon has been shown to be noninferior to traditional treatments for in-stent restenosis. The study, presented at TCT 2025, found the balloon to be safe and effective for treating ISR without adding extra layers of stents.
A study found that super-high-pressure non-compliant balloons (NCB) are non-inferior to IVL balloon catheters for lesion preparation and stent expansion in severely calcified lesions. The results showed similar safety profiles and efficacy across various patient subgroups.
A new drug-eluting balloon has been shown to match the outcomes of standard care for in-stent restenosis, offering a safer alternative for patients with multiple stent layers. The study's results suggest that patients with complex or multilayer ISR may benefit from sirolimus-eluting balloons as a viable treatment option.
Automated external defibrillators (AEDs) in private homes show effectiveness in improving patient outcomes for those with shockable rhythms during cardiac arrest. However, considering the rarity of cardiac arrest at home and current AED pricing, general purchase is not deemed cost-effective.
A cohort study found that night light exposure was a significant risk factor for developing cardiovascular diseases among adults over 40. Avoiding light at night may be a useful strategy for reducing the risks of cardiovascular diseases.
A large national cohort study found associations between adverse pregnancy outcomes and increased risk of atrial fibrillation up to 46 years later. Women with these outcomes require early preventive actions and long-term clinical follow-up.
Researchers at Gladstone Institutes discover a gene called HMGN1 that disrupts DNA packaging and regulation, leading to heart malformations in people with Down syndrome. Removing the extra copy of HMGN1 from mice with Down syndrome prevents heart defects, paving the way for potential treatments.
A recent study published in the European Heart Journal found that female bodybuilders are at a high risk of sudden cardiac death, with a mortality rate 20 times higher than amateur athletes. The study also revealed a significant proportion of deaths from suicide and homicide.
A study found that preexisting hyperlipidemia in pregnancy is associated with heightened risks of obstetric complications and early cardiovascular events postpartum. Women with high cholesterol are at increased risk of arrhythmias, acute coronary syndrome, gestational diabetes, and labor delivery complications.
A landmark study analyzed health data from over 600,000 patients across 10 countries to assess patient risk for non-ST-elevation acute coronary syndrome (NSTE-ACS). The AI-powered model GRACE 3.0 predicts risk more accurately and guides personalized treatment decisions.
A study of 5,794 adults found that different types of depression are associated with varying levels of risk for cardiometabolic diseases. Those with atypical/energy-related symptoms were more likely to develop Type-2 diabetes, while those with melancholic symptoms were at higher risk for cardiovascular disease.
Dr. Amit Khera, a leading expert in preventive cardiology, will receive the 2025 Chairman’s Award for his groundbreaking clinical studies and contributions to the field of cardiovascular risk assessment. He is recognized for his tireless efforts to strengthen the American Heart Association's Scientific Sessions.
The SCAI position statement highlights the advantages of intracardiac echocardiography (ICE) in improving safety, efficiency, and patient access for structural heart interventions. ICE offers real-time, high-resolution imaging without general anesthesia, streamlining procedures and reducing complications.
A study by the American College of Cardiology reveals that heart disease mortality is on the rise in California, with low-income communities bearing a disproportionate burden. The study found significant disparities in cardiovascular disease burden across counties, with high rates of hypertension, obesity, and diabetes associated with ...
The American College of Cardiology has selected three outstanding abstract presentations as Abstract Award winners. The conference brings together leading experts to examine emerging trends and evidence-based strategies in heart disease prevention and management.
Researchers use AI, omics, and systems biology to design targeted drugs for cardiovascular disease pathways. The tools could transform heart drug development and save lives, but global health policy leadership is urgently needed.
A new review in Frontiers in Science calls for a fundamental shift in how heart drugs are discovered and tested using AI, omics, and big data. This approach could drive the development of personalized treatments for cardiovascular disease, which currently relies on broad-brush treatments that don't account for individual variability.
Dr. Emelia Benjamin will receive the award for her sustained record of excellence in teaching and mentoring early- and mid-career clinicians and researchers. Her research focuses on atrial fibrillation, mobile health, inflammation, and chronic pain.
The FDA has approved AD-NP1 for human clinical trials, a monoclonal antibody that targets cellular metabolism to promote tissue repair of multiple organs. Funded by the National Institutes of Health and other sources, AD-NP1 has shown efficacy in mice and monkeys, and may benefit various organs beyond the heart after acute injury.
A new analysis found that virtual reality effectively reduced anxiety during coronary angiography and had more stable vital signs than standard care. VR was superior to standard care in reducing anxiety and associated with significantly lower changes in heart rate and blood pressure.