Articles tagged with Cardiology
Scientists at University Hospital of Bonn identified a signaling pathway in the immune system that helps newborn heart cells survive and regenerate after injury. The discovery opens new possibilities for therapies aimed at repairing damaged adult hearts, which have limited regenerative capacity compared to neonatal hearts.
Researchers found that cold storage platelets (CSPs) can control active surgical bleeding as effectively as room temperature platelets (RTPs), with potential benefits including reduced wastage and increased platelet availability. CSPs may also enable platelet incorporation into inventory at locations with limited shelf life for RTPs.
Columbia researchers have developed a new technique to capture electrical activity and mechanical motion within the heart using cardiac ultrasound images. This technology allows for early detection and risk assessment of Mitral Valve Disease and arrhythmias, transforming care for those suffering from these conditions.
A study from Karolinska Institutet found that people treated with modern NOAC blood-thinning medicines experienced a slower rate of cognitive decline compared to those receiving warfarin or no anticoagulant treatment. This was associated with lower risk of other health problems, including death, stroke, and fractures.
Researchers discovered a statistically significant reduction in premature atrial contractions after cannabis inhalation, with no impact on daily activity levels. The findings challenge assumptions about the cardiovascular effects of cannabis and may lead to new approaches for preventing or treating abnormal heart rhythms.
A hybrid lifestyle program showed potential benefits for cardiometabolic health among adherent participants with obesity, but failed to achieve significant weight loss. The study suggests further investigation into the program's effects on metabolic health.
A new ACC Scientific Statement highlights the importance of considering cognitive impairment and frailty in cardiovascular care for older adults. The statement outlines practical strategies for prevention, screening, assessment, and management, aiming to improve outcomes such as independence, mobility, and caregiver burden.
Objective physical fitness assessments reveal a graded association between balance, agility, strength, and cardiorespiratory fitness with reduced all-cause mortality. This study suggests integrating fitness assessments into routine practice may improve risk stratification and guide function-oriented interventions.
A study led by Dr. Michael Harrison found that regional dips in oxygen levels serve as a signal for the coordinated growth of heart muscle and coronary vessels. The system operates as a self-limiting feedback loop, with epicardial cells detecting hypoxia to activate genes that orchestrate expansion.
Tirzepatide has been shown to reduce the risk of heart attacks and hospitalizations due to infections in people with type 2 diabetes and obesity. The study found a relative risk reduction of about one-third, corresponding to a 36% reduced risk of infection-related hospitalization.
The ALARA+ Coalition has released a suite of resources to help hospital leadership and decisionmakers implement enhanced radiation and occupational safety guidelines for clinicians and staff working in fluoroscopy laboratories. The new toolkits provide practical steps to protect cath lab team members from both occupational radiation ex...
A U-shaped association exists between LVEDD and mortality in HF, suggesting high risk for both abnormally small and large ventricles. The findings support integrating LV size assessment into routine risk stratification to guide personalized management.
UC San Diego Health has been ranked as the top care facility in California and among the top 20 in the nation for eight medical specialties. The institution achieved this distinction through its patient-dedicated, collaborative spirit and commitment to delivering outstanding care.
For 15 years, Ochsner Health hospitals have ranked as the best in Louisiana for overall care, with numerous specialties and procedures recognized as High Performing by U.S. News & World Report. The hospital's obstetrics and gynecology service lines, including lung surgery, are among the top-ranked in the nation.
Research highlights importance of cardiovascular care in breast cancer patients and survivors throughout life. Cardiovascular risk factors and interventions are essential to prevent disease progression and improve quality of life.
A new program taught family physicians to perform echocardiography using an AI-guided handheld ultrasound device, reducing wait times and costs. The approach, piloted in nine clinics across Spain, estimates annual savings of €70,000 per clinic.
A study led by Robert Koeth found a connection between elevated blood levels of TMAO, a gut bacteria byproduct, and an increased risk of atrial fibrillation. The research team discovered that TMAO changes the heart's electrical environment, making it more susceptible to abnormal rhythms.
The American College of Cardiology introduces a new cardiogenic shock designation to address deadly gaps in heart attack care. The new designation aims to standardize protocols and improve outcomes for patients with life-threatening complications of a heart attack, particularly in underserved areas.
A large-scale prospective cohort study found that patients with blood type A had lower risks of all-cause and cardiovascular mortality. In contrast, blood type O's reputation of being at lower risk is partially due to lower plasma von Willebrand factor levels, but this did not explain the increased risk in blood type A patients.
The 2026 American College of Cardiology/American Heart Association/Multisociety Dyslipidemia Guideline reclassified approximately one-quarter of adults, with two-thirds reassigned to lower-risk categories and one-third to higher-risk categories. This shift was driven by differences in risk factors among males, non-Hispanic Black indivi...
A nationally representative analysis found substantial gaps in LDL-C control, with increasing disparities across primary prevention categories and underuse of lipid-lowering therapy. The study provides a contemporary population-level benchmark for the updated guideline framework.
The updated clinical guidelines broaden statin eligibility by looking beyond the next 10 years to a person's risk over several decades. The new recommendations apply to approximately 56.6% of adults ages 30-79, with an additional 21.5 million Americans now eligible.
The 2026 American College of Cardiology/American Heart Association guideline substantially expands the U.S. population recommended for primary prevention statin therapy, targeting lower-risk individuals. The updated recommendations aim to reduce atherosclerotic cardiovascular disease risk and improve public health outcomes.
A cross-sectional study reveals substantial commercial price variation for common cardiovascular services, influenced by payer contracting strategies and market dynamics. The findings underscore the need for greater transparency and regulatory oversight to promote efficient healthcare spending.
Researchers developed DeepHHF, an AI model that identifies patients at high risk of heart failure up to five years in advance. The model analyzes standard ECG recordings and detects subtle abnormalities that are often imperceptible to the human eye.
Research highlights the significant impact of modifiable risk factors on ischemic heart disease mortality in the US. High body mass index (BMI) and fasting plasma glucose levels have increased attributable risk over the study period, emphasizing the importance of addressing these factors to reduce mortality.
A new machine learning version of the Martin-Hopkins equation accurately assesses LDL cholesterol risk with minimal difference to the original, making it accessible to all laboratories. The simplified code enables clinicians and patients to make better decisions about starting treatments that prevent heart attacks and strokes.
Experts recommend implementing safer technologies and modernizing radiation safety standards to reduce preventable radiation exposure and orthopedic injuries. The consensus statement emphasizes the need for mandatory action to prioritize protecting healthcare workers, ensuring a healthy workforce for patients' access to lifesaving care.
Expanding heart failure care to pharmacists and nurse practitioner-led medication management can save approximately 10 lives and prevent 25 hospitalizations per 1,000 patients. This service is estimated to be cost-effective and improve patient outcomes, providing a roadmap for a stronger healthcare system.
A recent study evaluated the safety and effectiveness of the J-Valve Transfemoral System in treating symptomatic severe aortic regurgitation. The study showed sustained valve performance, meaningful symptom improvement, and evidence of reverse left ventricular remodeling at one year.
A large long-term study found that children who consume sugar-sweetened beverages and fruit juice have a higher risk of hypertension later in life. Replacing these beverages with whole fruits or water was associated with lower risk of hypertension.
A new study published in JACC found that women who consistently strength train showed substantially lower risk of major cardiovascular disease, particularly alongside aerobic activity and reduced sedentary time. Higher levels of resistance training were associated with lower risk of major CVD, especially myocardial infarction, with no ...
The American College of Cardiology has recognized 100 hospitals nationwide for their commitment to delivering high-quality patient-centered cardiovascular care. These institutions have demonstrated ongoing excellence through comprehensive accreditation, data-driven performance measurement and continuous quality improvement initiatives.
The American College of Cardiology has selected 47 clinicians to participate in its inaugural Fuster Prevention Forum, which focuses on early cardiovascular disease prevention. Participants will gain skills to enact change and foster a culture of prevention in their communities.
A new study published in JAMA found no significant difference between sodium bicarbonate and placebo in sustaining return of spontaneous circulation. The findings suggest that routine administration of sodium bicarbonate for patients with in-hospital cardiac arrest may not be necessary.
Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics its complex mechanical behavior. The study could help researchers better understand valve disease and develop new treatment approaches.
A new preclinical study by Amsterdam UMC researchers overturns a key assumption in the biological pacemaker field. They show that transcription factor TBX18 does not generate true pacemaker activity, while ion channel Hcn2 produces robust pacemaker function in the heart.
A new study by Karolinska Institutet shows that daily smartphone-based heart rhythm monitoring can reduce same-day cardioversion cancellations by 94.7% and save significant healthcare resources. The method, called CORAI, uses photoplethysmography to measure small changes in blood flow, allowing for accurate heart rhythm assessment.
Senescent cells that stop dividing but don't die can become abnormally active, causing inflammation and instability in blood vessel plaques. The study found that losing key regulatory proteins activates the CD38 enzyme, leading to a higher risk of blood clots and cardiovascular events.
The first national audit of advanced heart failure referrals reveals significant gaps in access to life-prolonging therapies, particularly for women. Women represent just 1 in 3 referrals, despite comparable disease burden.
Researchers from The University of Osaka found that treatment with five mRNAs effectively promoted cardiac repair and extended survival in mice with heart failure. The study showed that simultaneous administration of five therapeutic mRNAs reduced heart tissue damage and improved heart function.
Researchers used RNA therapy to target a genetic mutation causing heart failure, reducing protein aggregation and improving cellular abnormalities. The study provides insight into the biological mechanisms underlying treatment response and may accelerate the development of personalized treatments for genetic heart disease.
A new study found that a simple angiogram scoring system can identify patients whose heart muscle is still alive even when a major artery has been completely blocked. This breakthrough could change how cardiac patients are treated and help doctors make faster, more informed decisions.
Researchers developed an AI-based score from standard ECGs that reflect biological development on a spectrum rather than in fixed categories. The Electrocardiographic Sex Index (ESI) captures step-by-step changes of normal growth and hormonal changes, offering a more precise way to account for developmental stage.
The Mount Sinai Health System has opened the Carolyn Rowan Center for Women’s Health and Wellness, which brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research to deliver personalized, comprehensive care for women. The Center offers guided multi-visit experiences and coordinated care o...
A new study projects that climate change will significantly increase the risk of heat-related cardiovascular disease in the US by 2050. The Pacific Northwest and Southern/Midwestern states are expected to experience the highest and steepest increases, respectively. Targeted interventions for vulnerable communities are crucial to mitiga...
Researchers explore contrast-enhanced ultrasonography as a safer alternative to invasive hepatic venous pressure gradient for assessing portal hypertension. CEUS uses microbubble-based ultrasound contrast agents to track blood flow through the liver and surrounding vessels.
Researchers developed a new cardiac MRI-based measurement, eRVEF, to assess tricuspid regurgitation and improve mortality risk prediction. The study found that eRVEF predicted adverse outcomes better than traditional measures.
Researchers developed cardiac organoids to address limitations of cell-based therapies in myocardial infarction. These three-dimensional tissue constructs integrate into host tissue, improve cardiac function, and reduce scar size without arrhythmogenic effects.
A subgroup analysis of the CHAMPION-AF trial reveals that left atrial appendage closure (LAAC) efficacy and safety are not affected by age, suggesting it can be considered for suitable candidates regardless of age. The choice between LAAC and DOAC should be made on an individualized basis in a shared decision-making process with patients.
A meta-analysis of 10-year data from 4 randomized trials found no significant difference in all-cause mortality between DES PCI and CABG. Long-term follow-up supports considering both approaches for suitable patients.
Roxana Mehran is recognized for her impactful work on improving outcomes for patients undergoing interventional procedures. She has contributed to major trials, including the TWILIGHT trial, and advocates for women in medicine through initiatives like Women As One.
The ARTICA meta-analysis investigated the safety and effectiveness of coronary revascularisation in patients undergoing TAVI, providing comprehensive insights into the optimal role of PCI. The findings suggest a potential benefit of selective, physiology-informed PCI in patients with severe aortic stenosis and CAD undergoing TAVI.
Mount Sinai physicians will offer expert guidance and resources to keep pickleball players safe and healthy at more locations than ever before. The partnership aims to promote physical and mental well-being, as well as boost longevity through pickleball.
Pregnancy-related cardiovascular complications account for 20-30% of maternal deaths in the US. Researchers analyzed claims data to find that underlying cardiovascular risk drives these events, rather than older age. This may encourage doctors to address cardiovascular health before pregnancy.
A new AI-powered cardiopulmonary resuscitation instructor has been developed to support bystanders during out-of-hospital cardiac arrests. The study suggests that this technology could be a scalable public health intervention to save lives.
A major international study has identified ways to detect patients with hypertrophic cardiomyopathy at serious risk of sudden death, heart failure or other dangerous outcomes. The findings will help save lives by improving the ability to determine who is at greatest risk and spare low-risk patients from unneeded heart implants.
Researchers discovered a low dose of digoxin reduces heart failure-related deaths and hospitalizations by 19% and 25% respectively, making it an inexpensive and safe treatment option.
Children who engaged in regular outdoor play had lower sedentary time and higher moderate-to-vigorous physical activity in adulthood, while those experiencing exercise restrictions during childhood had lower adult physical activity levels. These findings support personalized lifestyle interventions for patients with CHD.
A Concordia-designed simulator models hemodynamics in reduced gravity environments, revealing key differences in blood flow and pressure patterns. The system successfully reproduced effective CPR on Earth and generated consistent blood flow under both normal and hypogravity conditions.