Articles tagged with Cardiology
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A new study found semaglutide to be an effective treatment for preventing secondary cardiovascular disease in US adults. The medication meets conventional thresholds when used alone, but its cost-effectiveness is improved with combination therapy.
A recent study found that respiratory syncytial virus (RSV) hospitalizations are associated with a higher risk of cardiorespiratory events, with some conditions experiencing elevated risks up to 180 days after admission. The findings highlight the importance of increasing RSV immunization in adults to mitigate this risk.
The Society for Cardiovascular Angiography & Interventions has released an expert opinion on the use of wire-free angiography-derived physiology (ADP) in coronary artery disease assessment. ADP uses computational modeling or AI to analyze standard coronary angiographic images, offering a potentially more efficient and effective approac...
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
A new AI tool has been developed to predict the chances of death, major bleeding, or another cardiac event in cancer patients who have had a heart attack. The ONCO-ACS score combines cancer-related factors with standard clinical data to provide individualized treatment recommendations.
A new study has identified optimized immunosuppressive strategies that allow transplanted iPSC-CMs to survive without immune rejection in non-human primates. The researchers found a triple-drug regimen consisting of methylprednisolone, calcineurin inhibitors, and mycophenolate mofetil reliably prevents acute immune rejection.
A nationwide survey found that 61% of Americans are unaware of non-statin medications to lower cholesterol, while 73% have never heard of lipoprotein(a) or coronary artery calcium score testing. Non-statin options include Ezetimibe, PCSK9 Inhibitors, and Bempedoic Acid, which can help patients at risk for heart disease.
Smartwatches with PPG and ECG functionality improve atrial fibrillation detection, detecting it four times more often than standard care. Researchers detected heart arrhythmia in 21 patients using smartwatches compared to five in those receiving standard care after six months of monitoring.
The joint statement highlights the significant impact of environmental stressors on cardiovascular disease, with an estimated 4-6 million deaths per year. It calls for urgent action to adopt stricter air quality and noise standards, phase out fossil fuels, and regulate toxic chemicals.
Researchers at the University of Houston have discovered that loss-of-function in epicardial proteins leads to left ventricular noncompaction, or spongy heart, causing pediatric-onset heart failure. A new therapeutic approach may prevent babies from being born with this life-threatening disease.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
Fine particulate matter and ozone exposure independently associated with poorer cardiac health outcomes in breast cancer patients treated with cardiotoxic therapy. Environmental exposure modifications are crucial to mitigate cardiovascular disease risk.
The Cities@Heart project aims to improve cardiovascular health in cities through integrated whole-city approaches, targeting obesity, high blood pressure, and diabetes. The consortium will design, pilot, and evaluate city-level strategies to reduce the burden of cardiovascular disease on urban environments and improve quality-of-life.
A new study reveals a significant association between police-related stress and physical markers of cardiovascular health risk in Black women. Women who expressed concern for their children's potential interactions with police had thicker carotid artery walls, indicating increased cardiovascular risk.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
A cohort study found that very high lipoprotein(a) levels increased the 30-year risk of cardiovascular disease among healthy women. Screening for elevated lipoprotein(a) may be warranted in the general population.
A new study from UCLA Health found that a cardiovascular risk score can predict who will develop serious eye diseases years later. Higher cardiovascular risk scores were significantly more likely to develop conditions like age-related macular degeneration, diabetic retinopathy, and glaucoma.
In a prespecified exploratory analysis of the SELECT randomized clinical trial, semaglutide demonstrated significant reductions in hospital admissions and overall time spent in hospital. This finding suggests that semaglutide has broader health benefits for patients with obesity and established cardiovascular disease.
Gracie Greenlaw, an 11-year-old patient with hypoplastic left heart syndrome, undergoes the world's first pediatric heart and liver dual organ transplant at Children's Hospital Colorado. The groundbreaking procedure, performed by Dr. Megan Adams' team, aims to improve her quality of life by addressing long-term complications from her h...
A novel analysis found that financial strain and food insecurity accelerate biological aging and increase mortality risk, surpassing traditional risk factors. The study emphasizes the need for targeted preventive interventions and patient-centered care to address social determinants of health.
Experts warn that nicotine-containing products, including vapes, heated tobacco, and shisha, cause cardiovascular damage regardless of delivery system. The report highlights a rapid rise in youth addiction fueled by flavours and social media marketing.
A new study published in the Canadian Journal of Cardiology suggests that strong and supportive relationships can improve heart health for individuals with cardiovascular disease. The review highlights the need to include intimate partners in cardiac rehabilitation programs to support long-term heart health and quality of life.
A large study found that a family history of cardiometabolic diseases increases the risk of progressive heart damage in adolescents, with increased glucose levels partly explaining this association. The study suggests that early intervention and healthy lifestyle habits can help prevent premature heart damage in children.
A study found cryopreserved platelets to be a cost-effective option for managing surgical bleeding in cardiac surgery, dominating liquid-stored platelets in this setting. Further investigation is required to assess the economic benefits of cryopreserved platelets in broader populations.
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A genetic variant is likely putting some children with myocarditis at higher risk of developing heart failure. The study found that 34.4% of children with dilated cardiomyopathy had a genetic variant, compared to only 6.3% of control children.
The Society for Cardiovascular Angiography and Interventions (SCAI) reviewed the 2025 Interventional Cardiology Fellowship Match results, noting that nearly all applicants successfully matched but 71 positions remained unfilled. SCAI attributes this to a lack of trainees in the pipeline, citing factors like radiation exposure and burno...
Researchers found that sudden cardiac death (SCD) among colorectal cancer patients decreased overall, but disparities remained based on age, sex, and geographic location. The study highlights the need for tailored heart monitoring and care strategies for cancer patients, particularly in underserved groups.
A randomized clinical trial shows that semaglutide improves glycemic control and weight outcomes in individuals with schizophrenia. The study suggests using glucagon-like peptide-1 receptor agonists as an early intervention strategy to reduce cardiometabolic risk in this population.
In-flight cardiac arrest is a rare yet catastrophic event that claims up to 86% of air fatalities. Implementing automated external defibrillators (AEDs) on board could significantly boost survival rates from 6% to up to 70%. The authors recommend standardized CPR protocols training, telemedicine integration, and mandatory AED placement.
The Society for Cardiovascular Angiography and Interventions (SCAI) and Cardiovascular Research Technologies (CRT) announce a new collaboration to elevate the field of interventional cardiology through shared education programming, legislative activities, and future research initiatives. The partnership aims to improve patient outcomes...
Large language models are revolutionizing cardiovascular imaging by automating the interpretation of quantitative perfusion data in nuclear medicine and cardiac magnetic resonance. They also enable personalized protocol optimization in coronary computed tomography angiography, leveraging federated learning for data privacy.
Researchers have identified a key mechanism behind statin-induced muscle damage, paving the way for new statins with reduced side effects. By understanding how statins interact with muscle proteins, scientists can design safer alternatives that preserve cholesterol-lowering benefits.
Withdrawal of tirzepatide after 36-week treatment led to 25% or greater weight regain in most participants within a year, reversing initial cardiometabolic parameter improvements. Continued obesity treatment is crucial for sustained benefits.
A new study found that current cardiac screening tools are not optimal and fail to identify half the people who are at risk of having a heart attack. The researchers assessed the accuracy of widely used tools, including ASCVD and PREVENT calculators, and found that nearly half of patients would not have been recommended for preventive ...
The ESC Digital & AI Summit showcases innovations like smartphone stethoscopes, voice-detected heart failure, and blood-spot analysis for early cardiovascular disease detection. Virtual training using 3D-printed and virtual hearts enables hands-on learning of complex cardiac procedures.
A new AI-driven app, AortaGPT, aims to improve diagnosis and treatment of heritable thoracic aortic diseases by translating complex genetics concepts into actionable care recommendations. The app can also detect subtle facial features associated with genetic conditions affecting the aorta.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
A new report from Northwestern University offers six practical strategies to improve the doctor-patient bedside encounter in an era dominated by AI. By employing these strategies, clinicians can strengthen patient-physician relationships, combat inequities, and reduce burnout, ultimately leading to better patient outcomes.
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
A study published in the Chinese Medical Journal identified GSTP1 as a key regulator that blocks JNK-driven ferroptosis, providing protection against DOX-induced cardiomyopathy. Overexpression of GSTP1 inhibited ferroptosis and improved DOX-induced heart injury.
Researchers discovered a threefold reduction in harm among patients with coronary artery stenosis who experience pulmonary embolism. Patients with CAS had lower signs of right ventricular strain, including heart rate and biomarker levels.
A new editorial highlights the importance of primary care in preventing heart disease in breast cancer survivors. The study found that most women do not go on to develop serious cardiac disease, but those with higher-risk chemotherapy, older age, or multiple cardiovascular risk factors may benefit from closer monitoring.
The Family Heart Foundation has launched the Lp(a) AW(a)RE initiative to educate primary care clinicians, healthcare insurance providers, and policymakers about high lipoprotein(a). The program aims to increase awareness, screening, and diagnosis of this genetic risk factor for premature cardiovascular disease.
Researchers have visualized intricate dynamics of heart cell interaction during repair, revealing how immune cells guide connective tissue and prevent overgrowth of scar tissue. The study provides a critical foundation for future research aimed at reducing scar formation and maintaining the heart's pumping capacity.
A study found a single mutation in the CD36 gene increases risk of dilated cardiomyopathy by 33% in individuals of African descent. This variant is more common in Black individuals and may account for 20% of excess DCM risk.
A new research project at Goethe University Frankfurt aims to shed light on the molecular pathways of epoxyeicosatrienoic acids (EETs) in cardiovascular diseases. The project will search for transmembrane proteins that bind to EETs and mediate their effects, with potential implications for developing new classes of drugs.
The study found that men, Black patients, and those living in low socioeconomic areas were disproportionately affected by the increased amputation rates. The authors emphasize the need for aggressive prevention, early diagnosis, and intensive risk factor management to address the growing burden of diabetes and PAD.
Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.
Researchers validate GLIS model as a reliable predictor of sarcopenia and mortality risk in older patients with heart failure, outperforming existing tests. The model's accuracy enables early detection of physical decline and poor prognosis, informing treatment planning and discharge decisions.
Researchers developed an algorithm to optimize pacemaker function usage, reducing battery power consumption and potentially extending battery life by years. By switching off unnecessary features, doctors can reduce the number of surgeries needed and lower associated costs for the NHS.
Dr. Bruce D. Gelb, a pioneering pediatric cardiologist and geneticist, is honored with the 2026 APS John Howland Award for his groundbreaking research on congenital heart disease and developmental disorders. His work has profoundly shaped our understanding of these conditions and elevated the field of pediatric medicine.
A new study published in TCT 2025 reveals that at least 4.7 million people aged 65-85 living in the US have moderate or greater valvular heart disease (VHD), and at least 10.6 million have clinically significant VHD. The prevalence of VHD increases with advanced age, highlighting the need for screening and treatment programs.
Dr. Hani K. Najm, a world-renowned congenital cardiothoracic surgeon, has been named the next vice president of the American College of Cardiology. He will assume his role during ACC.26 and is committed to advancing heart health for all, building on the organization's mission to optimize patient care and outcomes.
The ENCIRCLE trial found that the SAPIEN M3 system significantly reduced mitral regurgitation severity, improved heart failure symptoms, and quality of life for patients with severe mitral regurgitation. Over 95% of patients had little-to-no valve leakage at one year.
A new sirolimus-eluting balloon has been shown to be noninferior to traditional treatments for in-stent restenosis. The study, presented at TCT 2025, found the balloon to be safe and effective for treating ISR without adding extra layers of stents.
A study found that super-high-pressure non-compliant balloons (NCB) are non-inferior to IVL balloon catheters for lesion preparation and stent expansion in severely calcified lesions. The results showed similar safety profiles and efficacy across various patient subgroups.
The study found that cutting balloon angioplasty is noninferior to intravascular lithotripsy in treating calcified coronary artery disease. The procedure is also less costly, making it a reasonable strategy for managing significantly calcified lesions.
A large international study found that utilizing sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine DES implantation for treating de novo coronary artery disease. The results showed comparable outcomes, including low rates of cardiac death and target vessel myocardial infarction.