Articles tagged with Neurosurgery
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers tracked over 12,000 participants to estimate the lifetime risk of dementia, Parkinson's disease, and stroke. Preventive strategies could delay onset and reduce lifetime risk by 20-50% in theory, particularly for those aged 85+.
Researchers discovered how the brain encodes speech production, finding that it controls both goals (speech sounds) and individual movements (lip, tongue, and larynx movements). This breakthrough aims to develop better brain machine interfaces to decode speech for paralyzed individuals.
International neurointerventional societies have released new guidelines outlining the criteria for Level 1, 2 and 3 stroke centers. The standards specify requirements for treating a minimum number of stroke patients and performing specific procedures annually.
Researchers evaluated state-of-the-art optical technology in commercial-grade operating microscopes to detect fluorescence signals produced by pro-drug 5-ALA. They found variability in signal intensity and bleaching rates, highlighting the need for standardized methods and built-in standards for reliable detection and measurement.
A new study by Vanderbilt University researchers found that bile acids can reduce cocaine reward and cravings. The findings suggest targeting bile acid signaling in the brain may be a novel way to treat cocaine abuse.
A new study finds that clinical quality registries for surgery often exclude treatment-related adverse events, leading to misleading conclusions. The study analyzed data from Finland and compared it with US and UK quality registers.
Researchers have mapped the brain regions responsible for naming objects, a process that is crucial for individuals with neurodegenerative diseases such as Alzheimer's. The study's findings could lead to improved approaches for epilepsy and tumor surgery, reducing cognitive side effects.
Neurologist Camilo R. Gomez argues that the effect of time on ischemic stroke outcomes varies greatly among patients, with collateral circulation playing a critical role in determining treatment efficacy. He proposes a new approach to stroke care, taking into account individual patient variability and blood circulation patterns.
A new study reveals stent retriever thrombectomy can be effective for patients up to 24 hours after stroke onset, offering new hope for longer window of care. The analysis of combined NASA and TRACK registries found similar results between real-world and randomized trials.
A study found that delayed endovascular thrombectomy (EVT) for stroke patients reduces their quality-adjusted life years (QALYs) by 40 days and economic value by $10,000 per 10-minute delay.
A new study reveals that developing a standardized stroke protocol can significantly reduce the time it takes to treat ELVO stroke patients. The protocol, which includes having a neurointerventional team meet patients upon arrival, achieves a median door-to-recanalization time of less than 60 minutes.
A new study finds that advanced imaging software can diagnose large vessel occlusion in stroke patients more accurately, reducing transfer delays and improving outcomes. By streamlining care, hospitals can provide EVT treatment sooner, leading to better patient recovery.
Researchers found elevated levels of tau and ubiquitin C-terminal hydrolase L1 biomarkers after high-acceleration head impacts, even without clinical concussion. The study suggests a potential new avenue for reducing risk to young athletes through technological improvements and game rule refinements.
Researchers analyze RFK's injuries from 1968 assassination, noting similarities between then and now in gunshot wound care. They conclude that while aggressive treatment was made to save Kennedy, his severe brain injury would likely be fatal with modern techniques.
Researchers compared ancient Peruvian trepanation outcomes to those during the American Civil War and found a significant difference in mortality rates. The study suggests ancient Peruvians may have prevented infection through unknown methods, leading to better survival rates over time.
Researchers created personalized brain models using The Virtual Brain platform, accurately predicting the effects of tumors on brain connectivity. This breakthrough opens up new possibilities for integrating neuroimaging data with virtual brain modeling to enhance surgical planning.
A study found that serum NF-L concentrations showed promise as a biomarker for brain injury due to repetitive subconcussive head impacts, but further research is needed. The researchers also observed fluctuations in tau protein concentrations, which did not show significant differences between starters and nonstarters.
A new surgical imaging instrument using Scanning Fiber Endoscope (SFE) technology has been developed to detect the fluorescent glow of malignant brain tumors. This allows neurosurgeons to visualize the tumor more accurately, enabling them to remove more tissue and potentially improve patient outcomes.
The PRECISE4Q project aims to develop computer-based predictive modeling to personalize and optimize treatment strategies for stroke patients. The project will collect large data sets from different sources, integrating them into self-learning computer models to minimize the burden of stroke on individuals and society.
Researchers found increased myelin water fraction in white matter following mild TBI, indicating active remyelination process. However, this change may be associated with disorganized and less functional myelin, a potential risk factor for chronic conditions like CTE.
A new stereovision system guides surgeons during spinal operations, providing accurate renderings of where implants need to go. The system, developed by Dartmouth engineers and physicians, is expected to save up to 30 minutes in surgery time.
A simple one-page form given to patients ahead of their doctor visit can significantly improve satisfaction with the care they receive. The low-tech tool helps patients focus on what's important to them and provides real-time feedback to doctors on how well they're addressing their patients' concerns.
Scientists investigate TRPV1 receptor, found in immune cells, as potential target for TBI recovery. Activating TRPV1 may balance macrophage populations and promote M2s, reducing lingering inflammation and improving cognition.
The new Glasgow Coma Scale-Pupils score (GCS-P) tool combines GCS scores and pupil reactivity to provide a more comprehensive assessment of traumatic brain injury (TBI) severity and prognosis. The GCS-P has been validated to be as predictive as other, more complex models, while being easy to apply and communicate.
A new smartphone-endoscope device allows surgeons to perform intricate neurosurgical procedures with improved efficiency, reduced scarring, and shorter recovery times. The device's high-definition image provides a clear view of the surgical site, while its portability and affordability make it an attractive option for underserved areas.
Researchers found that mice increased their running on a wheel two hours before the door to the nebulizing chamber was open. The activated brain regions included those implicated in reward processing and craving: the orbitofrontal cortex, dorsomedial hypothalamus, and lateral septum.
Research in brain science and statistical modeling allows for safer anesthesia administration, reducing side effects and improving patient recovery. Brown's methods use EEG data to fine-tune anesthesia dosing, enabling the safe administration of less anesthesia.
A new study by the Keck School of Medicine of USC reveals that 67% of neurosurgery residents experience burnout during training, with factors including inadequate exposure to the operating room and hostile faculty contributing to the issue. The study's findings highlight the need for improved mentorship support to reduce burnout and pr...
Rice University statisticians developed a method to integrate neuroimaging scans to identify patients at high risk of continued seizures before surgery. The study found a subgroup with 5.8 times greater odds of postoperative seizures due to differences in brain networks.
This special focus issue of Future Oncology explores current and future image-guided interventions in oncology, including techniques such as fluorescence and optical imaging. The issue aims to provide a platform for researchers and clinicians to discuss recent advances in radiotherapy and personalized treatment approaches.
A Mayo Clinic study surveyed neurosurgeons on their attitudes toward ceasing practice and testing in late career. Most disagreed with an absolute age cutoff, while half favored additional testing for neurosurgeons 65 and older. The study highlights the need to focus on patient safety and assess a surgeon's capacity over time.
A large observational study found that overlapping surgeries in neurosurgery do not result in significantly different patient outcomes, including deaths, complications, and functional status. The research suggests that overlapping surgery can be safely performed and may increase access to specialists for more patients.
A Lithuanian professor has been awarded the Paper of the Year by The Congress of Neurological Surgeons (CNS) for his groundbreaking research on severe traumatic brain injury. The study found that longer durations of cerebrovascular autoregulation impairment events significantly correlate with worse patient outcomes.
Researchers developed a novel imaging technique to assess patients with lumbar spine degeneration, providing precise assessments of water content changes in the intervertebral disk. This technology aims to recognize and predict disease earlier, enabling better treatment choices.
Researchers studied exposure to high-magnitude head impacts in young athletes during football games and practice drills, finding that players in 'Back' positions sustained more head impacts than others. High-magnitude head impacts occurred more often in open field areas during games than in line of scrimmage.
A new study by Oxford University Press USA found that patients undergoing neurosurgical procedures between 9 pm and 7 am are at a higher risk of developing complications. The odds of complication more than doubled when accounting for the length of the surgery, highlighting the importance of performing surgeries during daylight hours.
A study of nine young athletes found that contact drills involving multiple players led to the highest number of head impacts, while open-field tackling resulted in high-magnitude impacts. The study suggests modifying or eliminating certain drills from practice sessions to reduce injury risks.
A new imaging tool using targeted fluorescent dye successfully lit up benign brain tumors in patients undergoing removal surgery, allowing surgeons to identify tumor tissue. The technique improved surgical outcomes, with a 73% gross-total resection rate and perfect concordance for post-operative MRI results.
The University of Arizona is conducting a Phase 2 trial to determine whether the peptide angiotensin 1-7 can mitigate or reverse cognitive deficits after bypass surgery. The trial involves administering the compound before and after surgery, with participants undergoing regular tests to evaluate their memory.
Researchers used advanced brain mapping techniques to preserve musician's musical ability during surgery. The study, published in Current Biology, sheds new light on how music is processed in the brain and its importance for individuals like Dan Fabbio, who relies on music as his livelihood.
The study found that closure of the left atrial appendage during open heart surgery significantly reduces the risk of stroke and silent cerebral infarctions. Patients who underwent surgical closure had a lower cumulative probability of an ischaemic event in the brain compared to those without closure.
Researchers found a significant decrease in white matter volume and integrity in infants who underwent general anesthesia and surgery, with implications for long-term brain development. The study suggests that further research is needed to understand the full impact of early anesthesia on human brain development.
A review of available evidence links methamphetamine use to a heightened risk of stroke among young people, with men twice as likely to succumb to haemorrhagic strokes. The most common type associated with taking the drug is a brain bleed rather than a clot.
Researchers developed a method to identify brain tissue most likely to generate seizures in people with epilepsy, offering new treatment strategies for drug-resistant cases. By analyzing EEG recordings and mathematical modeling, the team found that targeting specific brain regions could lead to enhanced surgical outcomes.
A new study published in the Journal of Neurosurgery found that smoking significantly increases the chance of brain aneurysm recurrence. Former and current smokers had a higher rate of recurrence compared to never smokers, emphasizing the importance of quitting smoking after endovascular treatment.
Researchers found that conscious sedation allowed for real-time brain function monitoring, enabling adjustments mid-surgery to reduce ischemic injury risk. The study shows promise in improving outcomes and decreasing risk associated with brain aneurysm surgery.
Temple University Hospital is introducing an endoscopic keyhole craniotomy approach for treating tegmen dehiscence and temporal encephalocele, two rare conditions affecting the skull. This innovative method reduces skin incision size, retraction on the temporal lobe, and risk of brain injury.
A report by three neurosurgeons highlights industry's growing role in funding neurosurgery research, while also addressing ethical concerns and disparities. The authors advocate for careful oversight and disclosure to maintain high ethical standards.
Researchers developed a noninvasive ICP monitoring device using advanced signal analysis algorithms. The study showed strong association between noninvasive and invasive methods, with good correlation between ICP values.
A new study found that combining intravenous thrombolysis (IVT) pretreatment with mechanical thrombectomy improves ELVO stroke patient outcomes, resulting in higher rates of functional improvement and lower mortality rates. The treatment approach was also associated with better safety outcomes.
The DAWN trial demonstrates the effectiveness of mechanical thrombectomy for acute stroke caused by large vessel occlusion performed more than 6 hours after onset. The study results offer hope to patients who miss the traditional 6-hour treatment window, allowing doctors to offer life-saving neurointerventional surgery.
Nearly 60% of mechanical thrombectomies occur during non-work hours, with peak periods between 8-11 p.m. The study emphasizes the importance of understanding procedure timing to optimize patient outcomes and optimize physician staffing at stroke centers.
Patients undergoing gastric bypass surgery experience altered sweet taste preferences, with RYGB producing more pronounced effects than VSG. This phenomenon may help clinicians predict patient responses to different surgeries and inform treatment approaches for obesity.
A new research group at the University of Cambridge aims to improve care for patients with traumatic brain injury (TBI) in low- and middle-income countries. The group will focus on preventing, investigating, treating, and improving outcomes for head-injured patients in these regions.
Researchers have identified a unique metabolic signature associated with epileptic brain tissue that can be detected noninvasively using magnetic resonance imaging. This breakthrough allows for precise identification of small regions of abnormal brain tissue in early-stage epilepsy patients.
A new study published in the Canadian Medical Association Journal found that patients experiencing delayed emergency surgery are at a higher risk of death and have longer hospital stays. The delays were primarily caused by staff and operating room unavailability, highlighting the need for spare capacity to ensure timely access to care.
Researchers at Mount Sinai Hospital have developed a novel technique to continuously monitor laryngeal and vagus nerve function during otolaryngology and neurosurgery procedures. This non-invasive method uses a special breathing tube to stimulate and record nerve responses, allowing surgeons to adjust their approach in real-time.
Researchers led by SDSU neuroscientist Stephanie Ries discovered that wide swaths of the brain work in parallel to retrieve correct words from memory, challenging previous assumptions about localized language processing. The study's findings could help speech-language pathologists develop strategies for treating disorders like anomia.
A new computational method uses data from medical imaging to create a color-coded 'digital lego brain' model that predicts organ deformation under surgical action. This allows surgeons to virtually rehearse operations and anticipate potential complications.
Researchers have developed a new device to map the brain during surgery, providing higher resolution neural readings than existing tools. The device enables doctors to perform safer, more precise brain surgeries by distinguishing between healthy and diseased tissues.