Articles tagged with Orthodontics
A study on mouse incisors reveals a cellular mechanism behind the unique decussation patterns of tooth enamel, which form the enamel's hardness through directional sliding and coordinated migration of ameloblasts. The findings provide new insights into how dental stem and progenitor cells maintain and repair enamel-forming tissues.
Researchers discover SMAD7 acts as a positive regulator of Wnt/β-catenin signaling, promoting dental pulp stem cell regeneration and tissue repair. The study provides new insights into the molecular mechanisms governing tooth regeneration and holds promise for regenerative endodontic procedures.
A new study by King's College London found that over 35% of patients without reported diabetes had high blood sugar levels consistent with pre-diabetes. The research uses a simple finger-prick blood test to screen for the condition, which can be done during dental appointments in as little as six minutes.
Researchers identified altered gene expression in smokers with periodontitis, leading to weakened gum epithelial integrity and excessive inflammation. A new target molecule, CXCL12, was found to drive immune-cell recruitment and inflammation, making it a potential therapeutic approach.
A clinical trial shows that arginine can modify plaque formation on teeth, thereby protecting against dental caries. The study found that arginine reduced the acidity of biofilms and altered their carbohydrate structure, making them less harmful.
A new composite hydrogel containing Li-Ca-Si bioceramics particles and gelatin methacryloyl matrix has shown promise in treating dental pulp infections by facilitating innervation and odontogenic differentiation. The hydrogel promoted Schwann cell regeneration, cytocompatibility for dental pulp stem cells, and proliferation of DPSCs.
George Belibasakis has been elected as the new Vice-President of IADR for the 104th General Session in 2026. He is currently Professor of Clinical Oral Infection Biology at Karolinska Institutet in Stockholm, Sweden, and his research focuses on deciphering the biological mechanisms underlying common oral diseases.
Kimon Divaris, a pediatric dentist and oral epidemiologist, was elected AADOCR Vice-President, while Mia L. Geisinger, a Professor of Periodontology at UAB, took on the role of IADR/AADOCR Publications Committee representative. Both leaders will serve during the 55th Annual Meeting in San Diego from March 25-28, 2026.
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
Researchers discovered that young dental cells are directed by their position along the lingual-buccal axis to grow into distinct structures. Cells on one side formed tooth enamel, while those on the other side focused on stem cell activity and supporting tissue growth.
Researchers from Korea University Anam Hospital and KAIST introduce an AI system that accurately predicts a child's pubertal growth peak from a single radiograph, streamlining orthodontic treatment. The Attend-and-Refine Network (ARNet-v2) improves efficiency and accuracy, reducing radiation exposure and costs for young patients.
Generative AI accelerates scientific discovery in oral sciences, but requires transparent disclosure and robust verification methods to ensure responsible integration. The use of AI in research demands human oversight, accountability, and continuous monitoring to maintain quality and credibility.
Researchers demonstrate that intraoral administration of abaloparatide combined with orthodontic force supports alveolar bone thickening. ABL-induced alveolar bone formation is linked to the focal adhesion pathway, where FAK activation plays a crucial role.
Research reveals that hypoxia reduces alveolar bone levels and osteoblast differentiation after orthodontic tooth movement, while increasing osteoclastic activity. This study provides critical insights into the bone remodeling process under hypoxia.
A new study published in JDR Clinical & Translational Research found that arginine dentifrices can significantly reduce childhood caries. The 8.0% arginine-containing dentifrice demonstrated a 26.0% reduction in DMFS scores compared to the control group.
Dr. Adekemi Adeniyan's innovative solutions to tackle oral health disparities in underserved communities have earned her the IHME's 2025 Roux Prize. Her work, using local data and community feedback, has expanded access to dental care for over 100,000 people.
The AADOCR Mind the Future Program will fund year six of its mentoring network program, supporting up to ten early-career investigators in dental, oral, and craniofacial research. The program aims to develop a sustainable national mentoring network enhancing career development for future researchers.
The AADOCR SCADA/Dentsply Sirona Research Award aims to support early-stage dentist-scientists by providing up to $10,000 for research projects and infrastructure establishment. The award's recipients must submit a report within 12 months of receiving the funding.
A study found that microRNA-27a promotes dental tissue regeneration by suppressing inflammation and activating Wnt/BMP signaling pathways. The researchers used human dental pulp stem cells to overexpress miRNA-27a, which led to the formation of new bone-like tissue in mice.
The consensus outlines evidence-based strategies for case selection, biomechanical principles, and clinical procedures to enhance clear aligner therapy. It introduces a novel difficulty-assessment tool and recommends tailored approaches for complex tooth movements, such as molar distalization and arch expansion.
A recent study published in Journal of Dental Research examined the relationship between early childhood fluoride exposure and cognitive development. The research found that there were no significant effects of fluoride exposure on cognitive neurodevelopment, with the hypothesis of non-inferiority tests also supporting this conclusion.
Raul Garcia has been elected as IADR Vice-president, aiming to enhance the role of IADR in mentoring a new generation of dental scientists globally. He brings extensive experience in clinical and translational sciences, oral health inequalities, and community-based interventions.
Margherita R. Fontana, Julie Frantsve-Hawley, and Ariadne Letra were elected as Vice-president, Treasurer, and Representative to the IADR/AADOCR Publications Committee respectively. Their terms commence at the 54th Annual Meeting of AADOCR in March 2024.
The new issue of Advances in Dental Research explores the impact of sex biology on women's health, highlighting disparities in dental disease prevalence. The meeting emphasized the need for a comprehensive approach to address these issues, including access to care and preventive measures.
A new supplement published by JDR Clinical & Translational Research examines the connections between oral health, behavior, and overall well-being. The study reveals strong evidence for the importance of integrated healthcare systems addressing these interconnected aspects.
The IADR and AADOCR published the revised OHStat guidelines to improve reporting in oral health research, incorporating CONSORT, STROBE, and SAMPL guidelines. The guidelines also recommend estimating results in clinically meaningful units using confidence intervals, rather than relying on P values.
Researchers at the University of Gothenburg have identified clear stress patterns among children undergoing dental treatment, particularly during anesthetic injections. The study used a sensor tool to monitor hand movements and sweating, revealing that invasive treatments were significantly more stressful for longer periods.
The International Association for Dental, Oral, and Craniofacial Research announced Enas Belal Abdellatif as the 2024 IADR Newell Johnson Travel Award winner. Abdellatif's research focuses on early childhood caries, oral epidemiology, and behavioral change interventions.
A new AI-powered tool developed by the University of Copenhagen and 3Shape predicts how teeth will move, allowing orthodontists to ensure braces are neither too loose nor too tight. The tool uses scanned imagery of teeth and bone structures to simulate how braces should fit, reducing trial and error.
The study found that network-level variables significantly improved model fit and displayed strong independent associations with oral health outcomes. Network proportion needing dental treatment was positively associated with current dental treatment needs, while exposure to reported dental visits decreased odds of no recent dental vis...
The IADR LION Dental Research Award recognizes innovative research in basic dental science and applied research achievements that improve public dental health. The 2023 recipients were announced during the 101st General Session of IADR in Bogot , Colombia
Chenmin Yao, a young researcher from Wuhan University, China, received the 2023 IADR Toshio Nakao Fellowship to support her training and experience in dental materials science. She has published nine papers in peer-reviewed international journals with high impact factors.
Richard Niederman has dedicated his career to generating evidence for oral disease prevention and promotion. He pioneered large-scale school- and community-based oral health programs focusing on fluoride applications.
Domenick Zero, an Indiana University professor, received the William H. Bowen Research in Dental Caries Award for his groundbreaking research on caries prevention and early detection. His work has improved oral health through innovative methods and tools, shifting focus from invasive treatment to tooth preservation.
The International Association for Dental Research (IADR) recognized six recipients of the 2023 IADR Colgate Research Travel Awards, which encourage research in preventing oral diseases. The award recipients received travel stipends and commemorative plaques to present their work at the annual conference.
The Journal of Dental Research (JDR) has published a special issue on aging and oral health, featuring research on biological mechanisms underlying age-related conditions such as cognitive decline. The issue aims to improve oral health care in older populations, promoting general health and well-being.
Michael Alfano was awarded the 2023 AADOCR Honorary Membership for his significant contributions to dental, oral, and craniofacial research. He is a renowned expert in improving higher education, particularly in dental education, and has made notable advancements in periodontal disease research.
A novel AI architecture, relational reasoning network, accurately identifies anatomical landmarks in CT scans for orthodontic treatments. The model learns spatial relationships between landmarks without explicit image segmentation, achieving accuracy comparable to conventional methods.
A study by researchers from Okayama University found that Japanese university students' willingness to undergo regular dental check-ups is associated with their thoughts regarding the health-belief model and oral health behaviors. The study suggests that the perceived benefit of undergoing regular check-ups drives young students toward...
A nationwide Australian study found no link between early exposure to fluoridated water and altered emotional, behavioral development, or executive functioning in adolescence. The study used data from Australia's National Child Oral Health Study and followed children aged 5-10 years for 7-8 years.
A new analysis found that increased Medicaid dental payment policies were associated with modest improvements in children's dental visits. The study also showed a link between the payment rates and better oral health outcomes for kids.
Researchers examined an abnormal tooth from an Otodus megalodon shark to determine the root cause of double tooth pathology. The study suggests that feeding-related injury may be the probable cause, as modern sharks with similar deformities are often caused by sharp objects piercing developing teeth.
A study found that childhood cancer survivors who received combined chemotherapy and radiotherapy have a higher risk of dental developmental anomalies. The first signs of dental disturbances can appear within one or two years after treatment. Researchers identified specific treatments and age factors associated with increased DDA risk.
Danish adults have made significant strides in preserving their natural teeth and visiting the dentist more frequently. However, social disparities in dental health persist, with those from lower-income backgrounds receiving less preventive care.
Sylvia Frazier-Bowers, an Associate Professor at the University of North Carolina at Chapel Hill Adams School of Dentistry, has been awarded the AADR National Student Research Group Mentor Award. She is recognized for her efforts to bridge the gap between clinical profession and scientific advances in dentofacial variation research.
A recent study from the University of Adelaide found that having braces does not necessarily lead to increased happiness or psychosocial outcomes in later life. In fact, people who did not receive orthodontic treatment were significantly more optimistic than those who had braces treatment.
Children with protruding teeth are at a higher risk of damage, but regular check-ups can reduce this risk. Early identification and protection through braces and good oral habits can prevent long-term dental issues.
A University of Adelaide study found that orthodontic treatment has no long-term impact on dental health. The research followed 448 participants from age 13 to 30 and found that those with straight teeth still required regular brushing and check-ups to prevent decay.
Researchers developed a film coating to prevent bacterial growth on dental retainers and aligners. The coated plastic showed improved durability and reduced bacterial growth by 75%, offering a potential solution for maintaining oral hygiene.
Researchers have developed liposomal nanoparticles that can deliver collagenase enzymes to remodel teeth in the mouth without surgery. This technology has shown promising results in pre-clinical studies, potentially leading to faster and less painful orthodontic procedures.
Researchers discuss conventional versus newly introduced treatment modalities for managing orthodontic pain, highlighting the importance of individualized assessment and case-by-case decision-making.
Osteocytes are identified as the major source of receptor activator of nuclear factor-κB ligand (RANKL) during orthodontic tooth movement, regulating bone remodeling and osteoclastic differentiation.
A new antibacterial orthodontic cement containing dimethylaminododecyl methacrylate (DMADDM) inhibits biofilm formation and reduces lactic acid production. The results show that the DMADDM-containing cement is promising for reducing demineralization in enamel around orthodontic brackets.
Researchers found that most orthodontists prescribed removable retainers, with 58.2% opting for these over fixed lingual retainers. Patient compliance was generally high, with 60% wearing retainers more than 10 hours a day in the first three months.
Researchers found potentially pathogenic microbes on at least 50% of orthodontic retainers, with Candida and Staphylococcus species commonly present. Biofilms on the retainer can be difficult to remove and have high levels of resistance to antimicrobials.
A new study by OHSU School of Dentistry found that patients with self-ligating orthodontic brackets retained significantly fewer oral bacteria in plaque compared to those with elastomeric brackets. The researchers also developed a rapid and reliable method for quantifying oral bacteria using ATP-driven bioluminescence.
Dr. Gregory King, a renowned researcher in craniofacial biology and orthodontics, has received the prestigious IADR Craniofacial Biology Research Award. The award recognizes his significant contributions to the field of bone biology and orthodontic tooth movement over a period of 30 years.
A survey of adults found that less metal is better when it comes to the attractiveness of orthodontic braces. Clear trays and teeth with no visible appliances were considered the most attractive options. However, these more aesthetically pleasing options often come with limitations in terms of movement and force delivery.
Dr. Sheldon Baumrind is honored for his extensive work in craniofacial biology, including clinical investigation and application of devices and engineering concepts. His research includes articles on randomized clinical trials, radiographic assessment, and orthodontics.
A novel teledentistry approach using teleconferencing increases access to limited orthodontic treatment for Medicaid-eligible children. Early intervention shows significant improvement in malocclusion severity.