Articles tagged with Pediatrics
The 'handshake stewardship' program, led by Sarah Parker, MD, reduced antibacterial use by 10.3%, antifungal use by 12.1%, and overall antimicrobial use by 10.9%. The program's success is attributed to daily pharmacist-physician reviews and in-person advice on antibiotic usage.
A worldwide survey found 16% of critically ill children have acute neurological conditions with brain damage, highlighting the need for transformational ideas to improve outcomes. The study revealed that cardiac arrest was the most common cause of these conditions, followed by traumatic brain injury and central nervous system infection.
Scientists at Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a promising target to treat AT/RT, a highly aggressive and therapy-resistant brain tumor, using CRISPR/Cas9 gene editing technology. The PLK4 inhibitor has been shown to stop tumor growth while sparing normal cells.
A study published in Pediatrics found that obesity significantly increases the risk of high blood pressure in Hispanic adolescents, with a prevalence rate nearly six times higher than in non-Hispanic peers. Researchers attribute this disparity to lack of data on health risks for Hispanic youth.
A video analysis study by Christopher P. Bonafide and colleagues investigated factors influencing nurse response times to bedside monitor alarms. The research found that nurse experience, alarm type, and hospital environment all played significant roles in shaping response times.
A team of researchers from UTHealth will increase low vaccination rates among pre-kindergarten and kindergarten students in the Houston Independent School District. The project aims to achieve immunization rates as high as those in major school systems in the US, particularly among children with limited access to medical care.
A new study analyzed the biomechanics of head injury in pediatric patients with concussions, using physical and computational models to simulate impacts. The researchers found that youths are at higher risk of concussive injury at lower event severities, but no clear predictors for persistent symptoms were identified.
A meta-analysis of 404 pediatric patients found that antibiotic treatment was successful in 90.5% without increasing the risk of complications, but failure rates were higher in those with appendicolith; surgery is preferred for cases with this condition.
A survey of over 17,000 parents of hospitalized children found variability in quality of care across US children's hospitals. The study highlights opportunities for improvement in communication, family engagement, and patient safety.
A new study found that pediatric opioid exposures have been steadily decreasing since 2009, except for buprenorphine. Researchers call for changes to prescribing practices and increased education on safe storage at home.
According to a large international study, one out of four children in ICUs develops delirium. The prevalence nearly doubles after five days, highlighting the need for routine monitoring.
David A. Spiegel, a pediatric orthopedic surgeon, has spent over 20 years providing humanitarian care to children with clubfoot conditions in Nepal and internationally. He introduced the Ponseti method for treatment, which has benefited over 4,000 feet at the Hospital and Rehabilitation Centre for Disabled Children.
A new Loyola study reveals that physicians-in-training possess a high level of emotional intelligence, scoring in the high range on an emotional intelligence survey. The study found that pediatric and med-peds residents scored highest in empathy and social responsibility, but lowest in assertiveness.
The study provides recommendations to optimize decision-making for medical imaging in pediatric orthopedic care, highlighting the risk of cancer and genetic defects from radiation exposure. Best practices to reduce radiation include limiting precise collimation, fluoroscopy bursts, and utilizing low-dose CT protocols.
Researchers found no improvement in mid to long-term outcomes for children who received bone morphogenetic proteins during spinal fusion surgeries. The study suggests caution when using BMPs in pediatric patients, as they may not provide additional benefits or improve safety.
A Rutgers study finds that an estimated one in six US children have development disorders, but only 1,000 developmental pediatricians exist nationwide. The study also reveals a lack of programs offering accommodations for non-English speaking families, resulting in extended wait times and delayed diagnostic evaluations.
A study found that children who don't get enough sleep between 3-7 years old are more likely to have attention, emotional control, and peer relationship issues. The research also showed a higher risk of poor neurobehavioral function at age 7.
Research from Children's Hospital Colorado found that wearing a helmet while skiing or snowboarding lowers the risk of sustaining severe head injuries. The study also discovered that nearly twice as many local Colorado children wear helmets compared to out-of-state visitors.
Researchers at Northwestern University have found a molecule that stops the growth of diffuse intrinsic pontine glioma (DIPG), a fatal pediatric brain tumor. The study, published in Nature Medicine, reveals the molecule detaches proteins that enable cancer cells to grow, offering new treatment options for children under 10.
A systematic review of PDE-5 inhibitor use in pediatric patients with pulmonary hypertension found improvements in oxygenation, hemodynamics, and clinical outcomes. The evidence suggests that low- and moderate-dose sildenafil are safe regimens for children, outweighing the risks associated with long-term use.
Children's Mercy has developed a groundbreaking app called CHAMP to monitor single-ventricle babies, reducing mortality rates and improving patient care. The program uses Microsoft devices and services to track vital signs and trigger alerts for instant evaluation.
Research at Boston Medical Center found that stronger alcohol policies in states reduce the number of young people who die in crashes caused by drunk driving. The study used an alcohol policy scale to assess 29 policies across the US, correlating them with the number of underage deaths in alcohol-related crashes.
A recent NICU study found that preemies are exposed to noise levels higher than recommended by the American Academy of Pediatrics, while also lacking essential language stimulation. The researchers recommend engaging parents in providing sensory exposures to promote healthy development.
A nationwide study published in JACS found that critically ill children can now undergo liver transplantation and achieve similar survival benefits as stable children. Survival rates have improved significantly since pediatric critical care was recognized as a specialty area of medicine, with one-year survival increasing from 66% to 92%.
A new study from the University of Eastern Finland found that high levels of moderate-to-vigorous physical activity are associated with lower arterial stiffness in 6-8-year-old children. Children who engage in at least 68 minutes of moderate-to-vigorous exercise per day have better arterial health.
The new e-tool has strong potential to encourage parents to make healthy lifestyle changes for their children, improving their diet and activity habits. Almost half of participating parents said they used the resources they selected from the tool.
The Endocrine Society has issued a new clinical practice guideline for pediatric obesity, emphasizing the importance of family-centered lifestyle modifications. The guideline provides recommendations for assessing, treating, and preventing childhood obesity, including genetic testing for rare causes.
A group of medical experts has issued new clinical guidelines for managing children and adolescents with growth failure, recommending hormonal treatments for certain conditions but cautioning against routine use in cases of unknown cause. The guidelines aim to balance medical needs with potential risks and long-term consequences.
A recent clinical trial found that controlling critically ill children's blood sugar levels within a usual care range does not offer significant benefits. In contrast, lower targets increased the risk of hypoglycemia without providing extra advantages.
Pediatric experts warn that consumer-use baby monitors may cause undue alarm to parents and have no evidence of medical benefits for healthy babies. The devices, marketed aggressively to parents, promise peace of mind about their child's cardiorespiratory health but have been shown to be inaccurate and potentially harmful.
Researchers at St. Jude Children's Research Hospital have developed new diagnostic screening and treatment recommendations for high-risk pediatric patients with acute megakaryoblastic leukemia (AMKL). The study identified three genetic alterations that can predict treatment success, enabling personalized medicine approaches.
A new study by Dana-Farber Cancer Institute researchers found that genetic abnormalities can guide patients' treatment for pediatric brain tumors. The study analyzed over 200 tumor samples, revealing clinically relevant genetic changes in 56% of cases, which can impact diagnosis and treatment with approved drugs or agents.
The Philadelphia Pediatric Medical Device Consortium awarded $50,000 grants to three companies developing innovative medical devices for children. These devices include a powered orthotic arm brace, a hand-operated rapid blood delivery system, and an ear reshaper designed to correct deformed ears in babies.
A 9-day-old baby who suffered a normally fatal stroke was saved after Dr. Alexander Drofa removed the clot by combining mechanical and medicinal therapies. The infant's coma made the case particularly challenging.
Research reveals that top-grossing PG-13 movies have more frequent and graphic gun violence than comparable R-rated films, with little attention to consequences. The study suggests that Hollywood prioritizes action-oriented films over responsible portrayals of gun violence, raising concerns about its impact on children.
The American Psychological Association emphasizes the importance of psychologists in patient-centered medical homes, highlighting their role in improving health outcomes, decreasing costs, and enhancing patient experience. Behavioral health problems are prevalent among medical patients, compounding care delivery and effectiveness.
Pediatric tuberculosis remains a concern in Canada, particularly among Aboriginal communities and children from endemic countries. Effective treatment requires a multidisciplinary approach, including clinicians, nurses, and social workers.
A recent study published in Annals of Emergency Medicine reports a case of a 6-year-old child who ingested liquid nicotine from an e-cigarette, requiring intubation and ICU admission. The patient's mother had mixed the liquid herself, resulting in a highly concentrated substance that caused severe symptoms and altered mental status.
Researchers found that consuming zinc-enriched foods can reduce oxidative stress and DNA damage in humans. The study suggests a new strategy for measuring the impact of zinc on health, with implications for mitigating micronutrient deficiencies worldwide.
Healthcare spending on children in the US grew from $149.6 billion in 1996 to $233.5 billion in 2013, with the highest expenditures on well-newborn care, ADHD treatment, and dental care. The study highlights the need to analyze driving factors behind increased healthcare spending to determine its impact on processes and outcomes.
Researchers identified gene mutations associated with steroid resistance in pediatric T-cell acute lymphoblastic leukemia, leading to poor clinical outcomes. A new therapeutic approach targeting individual signaling proteins restored steroid sensitivity in leukemic cells from patients.
A study of 3,063 children and adolescents with acute concussion found that physical activity within 7 days of injury was associated with reduced risk of persistent postconcussive symptoms. Engaging in early physical activity was linked to a lower risk of PPCS, regardless of intensity or exercise type.
Using cardiac imaging during heart surgery can detect serious residual holes in the heart that may occur when surgeons repair a child's heart defect. Pediatric experts say this tool, called transesophageal echocardiography (TEE), improves outcomes for children with congenital heart disease.
A new report calls for improved healthcare systems to address congenital heart disease, saving millions of children's lives. Urgent action is needed to prioritize pediatric cardiac workforce development and data collection.
A survey of 393 hospital neonatal intensive care units found only 56% believe there are enough ophthalmologists to screen and treat retinopathy of prematurity. Screening can be done with telemedicine, but only 21% of respondents used retinal imaging devices, with half being unsure about its safety.
A national NIH initiative will use exercise to identify molecular changes that improve and preserve health in children. Researchers will analyze blood samples from over 360 children before, during, and after exercise.
A new study identifies four culturally sensitive mental health screening tools that can be used by pediatricians to screen Latino children. The tools assess emotional and behavioral problems and are available in Spanish, with one including pictorial cues. The researchers hope that these tools will increase primary care pediatricians' c...
A recent publication from the Medica Research Institute highlights the need for addressing workforce disparities in pediatrics. Young investigators and seasoned researchers discuss key challenges, such as racism and discrimination, and offer guidance on career development and mentorship.
The UA Steele Children's Research Center is studying autoimmune disease triggers with a $1.73 million NIH grant, focusing on dendritic cells and immune tolerance. The research aims to identify new targets for therapeutic approaches to restore tolerance in patients with autoimmunity.
A Stanford patient has become the first infant to receive an experimental drug that shows significant improvement in motor milestones and function. The drug, nusinersen, is being rapidly progressed through regulatory approval, with FDA approval expected within two months.
A team of scientists has unveiled a novel role for thymic dendritic cells in regulating T cell egress into the bloodstream. This discovery could lead to new treatments for autoimmune diseases and cancer by understanding how the body regulates lymphocyte trafficking.
Researchers from UH Rainbow presented data on improving clinical outcomes for pediatric hematologic disorders, including findings on acquired aplastic anemia treatment algorithms and red blood cell transfusions in critically ill children. The studies aimed to improve long-term outcomes and transplant options for these rare diseases.
The new guidelines developed by the NASPGHAN recommend regular screening for NAFLD in all obese children between 9-11 years old using a simple liver enzyme test. Lifestyle changes such as improving diet and increasing physical activity are also recommended as first steps in treatment.
A new study presents alarming data on chest injuries in pediatric patients after all-terrain vehicle (ATV) accidents. The study found that pulmonary contusion, pneumothorax, and rib fractures were common, with 8 children dying from their injuries.
A new study found that pediatricians in the US underdiagnose hypertension and prehypertension in children aged 3 to 18 by as much as 95%, leading to inadequate treatment. The study analyzed electronic health records of over 400,000 children and revealed that only 6% of those with diagnosed hypertension received prescribed medication.
A study of 577 children living in Puerto Rico found that closer proximity to major roads was associated with higher levels of interleukin 31, a cytokine promoting allergic inflammation. This increase in IL-31 levels is linked to increased asthma risk and severity in genetically susceptible children.
A survey of 1,000 US parents found that 91.5% agreed use of placebo is vital for advancing new treatments, but only a majority accepted it for seven common conditions. The study highlights the need to refresh traditional pediatric therapeutic models to support parental decisions around placebos.
A study of over 3,900 US children who suffered cardiac arrest outside a hospital found that those receiving bystander CPR had better survival rates and neurological outcomes. Racial disparities in CPR provision were also noted, highlighting the need for education interventions to improve minority community access.
A new study found that intensive multidisciplinary treatment can eliminate dependence on tube feeding in 71% of children with pediatric feeding disorder at discharge. Treatment also leads to increased oral intake and reduced caregiver stress.
The program, launched in 2012, has generated over 506,000 customized prescriptions for an estimated 200,000 or more patients. More than 83% of participants reported the personalized referrals were 'very useful.'