Articles tagged with Pediatrics
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A study of Italian sixth- to eighth-graders found a high rate of gambling, which was associated with substance use and other risk-taking behaviors. The study suggests that parents and healthcare professionals should be aware of the potential risks of gambling in early adolescence.
A powerful three-way mechanism driving childhood brain cancer growth has been discovered by scientists. The MYB-QKI gene fusion is found in rare pediatric glioma subtype angiocentric glioma and drives tumor formation through abnormal expression, disruption of tumor suppression, and activation via a positive feedback loop.
A recent study identified the genetic mechanism causing angiocentric gliomas, a rare type of low-grade glioma in children. The discovery revealed an unusual DNA abnormality that triggers three different mechanisms to produce a tumor, leading to the development of a diagnostic test.
Dr. Sing Sing Way, a pediatrician specializing in infectious diseases, has made significant contributions to understanding pregnancy complications and infection susceptibility in newborns. His research has the potential to develop vaccines that protect against pregnancy complications.
Researchers have identified an abnormal fused gene that drives pediatric brain tumors through three distinct biological mechanisms. This finding may advance diagnosis and treatment by identifying the MYB-QKI fusion gene as a defining event in angiocentric glioma, allowing for targeted therapies.
A delegation of US pediatricians, led by Dr. Stephen Berman, will meet with their Cuban counterparts in Havana to collaborate on improving child health. They will share advances in early brain development and responsive parenting, while learning about Cuba's success in community-based primary care.
The iCat study successfully used clinical genomic sequencing to recommend therapy or diagnose changes in children with solid tumors. The findings support the use of personalized treatment based on tumor genetic characteristics, fueling potential drug development for pediatric and rare adult tumors.
A three-year study funded by PCORI investigates the safety and patient preferences of discharge strategies after chemotherapy for children with acute myeloid leukemia. The study aims to gather data on bloodstream infections and chemotherapy delays to inform better care for these vulnerable patients.
The first FDA-approved immunotherapy for pediatric cancer, dinutuximab, has been shown to be equivalent to the commercially produced version and can be made available to all patients. Clinical trials have demonstrated improved event-free survival and overall survival in children treated with the treatment.
The study found that 7.7 million deaths occurred globally in 2013, with lower respiratory tract infections, preterm birth complications, and malaria being the leading causes of death among children under 5. The report highlights the need for effective interventions to prevent these preventable causes of death.
Researchers discovered normal p53 gene action restrains transposons, mobile genetic elements that can lead to genomic instability. Disabling p53 allows transposons to erupt, causing disease.
Research by Peter Kriz found that less physically mature male ice hockey players took an average of 54 days to recover from concussions compared to more physically mature peers. The study recommends age-based grouping in youth sports leagues to reduce the risk of prolonged concussion symptoms.
Researchers identified the NLRP3 inflammasome's role in activating Interleukin 1 beta, triggering inflammation and BPD development. Testing FDA-approved drugs showed promise in reducing lung damage.
Researchers at Wake Forest Baptist Medical Center found an association between obesity and the formation of blood clots in children and adolescents. Obesity was a statistically significant predictor of blood clot formation in juveniles, contributing to increased incidence of pediatric venous thromboembolism.
A study published in The Journal of Allergy and Clinical Immunology found that preventative treatment with omalizumab reduces fall exacerbations in a high-risk group of allergic asthma subjects. Increasing inhaled steroid treatment levels offered little to no additional benefit.
The Philadelphia Pediatric Medical Device Consortium awards $50,000 seed grants to Actuated Medical and ENTvantage Diagnostics to improve bone biopsies and diagnose sinus infections in children. This funding aims to reduce pain and unnecessary antibiotic prescriptions.
A study from Northwestern University found that many parents are unaware of how to use an epinephrine auto-injector and have a written emergency food allergy action plan. The guidelines for treatment are not being followed, highlighting the need for improved communication between doctors and parents.
A team of researchers is exploring the use of the NAO robot in a new approach to pediatric rehabilitation based on social interaction between robots and humans. The robot can read moods, recognize family members, and learn preferences, providing personalized interventions for children with motor disabilities.
A team of healthcare workers developed guidelines for treating Ebola-infected children, recommending an aggressive approach that includes fluid therapy, highly fortified food, and increased bedside care. The protocol aims to improve survival rates among young patients and provide a basis for future outbreaks.
Two studies found that recurrent acute and chronic pancreatitis in children has a high disease burden, with 42% rate of rehospitalizations and estimated annual healthcare costs of $40,000. The studies highlight the need for information and research to prevent suffering and reduce costs.
The St. Jude Children's Research Hospital has developed ProteinPaint, a web application and dataset that provides an interactive tool for researchers worldwide to advance their understanding of pediatric cancer mutations. The tool offers critical information unavailable with existing visualization tools, allowing users to see the impac...
A new meta-analysis found that psychological therapies can reduce IBS symptoms for at least six months after treatment ends. The study analyzed 41 clinical trials involving over 2,200 patients, revealing no significant difference in effectiveness between different types of psychotherapy.
A new study found that 95% of families made at least one error in car seat use, and 91% made a serious error. The most common mistakes included loose harnesses, incorrect installations, and low chest clip positions.
A study published in JAMA Surgery found that nonoperative management with antibiotics was an effective treatment strategy for children with uncomplicated appendicitis, resulting in fewer disability days and lower healthcare costs. The study also showed no difference in health-related quality of life at one year.
A recent study at Rush University Medical Center found acupuncture to be a safe and effective adjunctive integrative medicine treatment for chronic pain in pediatric patients. The study included 55 children aged 7-20 who experienced chronic pain conditions, with significant reductions in pain levels and related health issues.
A study found that earlier intervention leads to better weight recovery in young children with multiple household risk factors, such as poverty and single parenthood. The pioneering use of video recordings helps families establish healthy habits and mealtime routines.
A review of 18 studies found that health professionals' knowledge of female genital mutilation (FGM/C) varies greatly according to their work setting. FGM/C is a harmful practice affecting 100-140 million women worldwide, with long-term complications including recurrent urinary infections and psychological problems.
A study analyzing DNA from over 1200 CHD patients found overlapping genetic influences during early childhood development, suggesting a link between heart defects and neurodevelopmental delays. The research identified 21 genes harboring protein-damaging mutations in more than one patient, which may lead to targeted therapies.
A pediatric chemotherapy regimen significantly improved outcomes for young adults with acute lymphoblastic leukemia (ALL), with a three-year overall survival rate of over 70%, according to Dana-Farber Cancer Institute scientists.
A study of over 99,000 children found that weight increase during the first year of life is associated with a higher risk of developing type 1 diabetes. The average change in weight from birth to 12 months was linked to an increased risk, while length gain showed no association.
A study conducted by Penn researchers found that teens understand the risks of distracted driving and cellphone use, but still engage in these behaviors. The study also revealed that context plays a significant role in how teens differentiate between texting and social media use.
A study by Cincinnati Children's Hospital Medical Center found that hospital-to-home transitions can cause mental exhaustion, emotional toll, and uncertainty among family caregivers. The researchers identified a need for in-home follow-up visits, telephone calls from nurses, and enhanced care plans to improve the transition.
A recent study found a significant increase in infant deaths and injuries caused by crib bumpers, with 48 deaths specifically attributed to the bedding accessory between 1985-2012. The researchers recommend a nationwide ban on crib bumpers due to their role in suffocation and strangulation incidents.
Children in low-income families experience greater access to preventive medical and dental care under Medicaid or the Children's Health Insurance Program (CHIP) than those with private insurance. Despite this, accessing specialty care remains a challenge for all types of insurance coverage.
A 2-year-old girl was diagnosed and treated for XDR TB, the first detailed account of a young child in the US. The successful treatment highlights the need for better understanding and creative approaches to pediatric tuberculosis.
Researchers developed a novel 3D computer modeling system to assess compatibility of potential donor hearts with children receiving heart transplants. The new system uses MRI and CT images to predict the best donor body weight for pediatric transplant recipients, improving size matching and potentially reducing mismatched organs.
A study published in the American Journal of Transplantation shows that new policies could increase pediatric lung transplants by twice as much. The research team tested alternative allocation models to improve pediatric access to donor lungs and found two models resulted in significantly more transplants for pediatric patients.
Research by University of Colorado School of Medicine faculty found that one in five pediatricians dismiss families who refuse vaccines. The study suggests that states with philosophical exemption laws and easier exemption processes have lower vaccination rates and higher rates of vaccine-preventable diseases.
Pediatric researchers have developed new growth charts for U.S. children with Down syndrome, providing a tool for pediatricians to evaluate growth patterns and nutritional status. The new charts show improvements in weight gain and height for children under age three, while also creating BMI charts to screen patients for excess body fat.
The American Academy of Pediatrics recommends increasing the minimum age to purchase tobacco products, including e-cigarettes, to 21 nationwide. The AAP also urges regulations to reduce youth access, increase prices, and promote smoke-free environments to mitigate the risks of tobacco and nicotine use.
The American Academy of Pediatrics (AAP) has released a policy statement linking climate change with the health of children. The statement highlights the unique vulnerability of children to climate-related threats, including heat stress, air quality issues, and increased infectious diseases.
A new study examines the effectiveness of a shaken baby syndrome prevention program, Period of PURPLE Crying, which was implemented in North Carolina from 2009-2012. The program, teaching parents about normal infant crying, resulted in a decline of calls to nurse advice line but no significant change in AHT rates.
A statewide shaken baby prevention effort implemented in 2007 reduced crying-related calls to a nurse advice line by 20% for children under 3 months and 12% for those ages 3-12 months. However, the study found no association between the intervention and state-level rates of abusive head trauma.
The American Academy of Pediatrics recommends that youth football leagues enforce proper tackling techniques, expand non-tackling leagues, and provide skilled athletic trainers to reduce injuries among young athletes. The AAP aims to balance the recreational benefits of the game with the health risks associated with tackling.
Research shows that skin-to-skin snuggling between mothers and babies can decrease maternal stress levels, improving parent-child bonding and breastfeeding rates. The study found a significant reduction in maternal anxiety, feeling helpless, and stress related to NICU experience.
A study by Eric J. Peng found that each extra inch of adult height correlates with an average increase in yearly income, with men earning $1,660 more per year for every inch above 64 inches and women earning $1,186 more per year for every inch above 59 inches.
A new study reveals that high school female athletes are most likely to experience ACL injuries while playing basketball, soccer, and lacrosse. The rate of injury per exposure is higher in girls than boys, particularly in these high-risk sports.
A new rule restricting full-contact tackling during high school football practices has been shown to significantly reduce concussion rates among players. The American Academy of Pediatrics study used data from over 16,000 adolescent athletes and found a nearly twofold decrease in concussions after the rule change.
More than two-thirds of health food store sales attendants recommended creatine to a researcher posing as a 15-year-old athlete, despite American Academy of Pediatrics' recommendations against use in minors. Sales attendants were also more likely to recommend creatine to male athletes.
A survey of over 6,000 schools found that nearly 22% of anaphylactic events occurred in individuals with no previously known allergies. The majority were treated with epinephrine auto-injectors, and the most common triggers included food and insect stings.
Urban teens identify improving employment opportunities, after-school activities and a cleaner city environment as key solutions to reduce violence. The study found that 61% of youths reported having a family member killed in an act of violence, highlighting the need for targeted prevention strategies.
A study by the American Academy of Pediatrics found that nearly 1 in 6 advertisements for children's products in top parenting magazines conflicted with health and safety recommendations. In over half of these cases, ads promoted messages that could put a child's life at risk, such as unsafe sleep positions and choking hazards.
A study by the American Academy of Pediatrics found that only 2% of commonly searched websites for firearm storage guidance correctly identified all four safety practices. The four measures include keeping guns locked and unloaded, and storing ammunition in a separate location.
Babies born to mothers traveling to the US for birth have significant medical complexities, longer hospital stays and increased re-hospitalization. The study found an average maternal age of 4 years older, doubled median hospital stay length and higher mortality rate compared to control group.
A new study found that hands-on training with chest compressions without mouth-to-mouth ventilation increased students' willingness to perform CPR on actual victims. The American Academy of Pediatrics recommends an effective way to teach large groups of people lifesaving skills and increase their willingness to use them if they witness...
A new study suggests that a mother's use of marijuana during pregnancy may indicate the use of other illicit drugs. The study found that 26% of mothers or their newborns tested positive for THC, with concurrent detection of opioids (12%), amphetamines (11%), and cocaine (6%) also common.
A study analyzed 15,613 pediatric ED visits due to legal interventions between 2008 and 2010. Most injuries resulted from blows or manhandling, affecting mostly males and teenagers. The issue comes with significant financial costs, including $16.3 million in total ED charges.
A new study reveals that nonpowder firearms like airsoft and paintball guns can cause severe injuries in pediatric patients. Twenty-nine percent of the children treated for nonpowder gun injuries required surgery, highlighting the need for stricter regulations on muzzle velocities to prevent such incidents.
A study found that over 40% of coaches and 50% of parents believe it's acceptable to let young athletes back into the game before receiving medical clearance, despite guidelines recommending caution. The research aims to raise awareness on safe return-to-play protocols to ensure child athletes receive proper attention after head hits.
A new study has identified 28 barriers to mental health services for US adolescents affected by bullying, including inadequate screening and counseling by medical providers. The findings highlight the need for improved communication between medical providers, school officials, and parents to ensure access to mental health services.