Researchers at Illinois provided insight into the signal transduction mechanism utilized by Staphylococcus aureus's TCS ArlRS in response to host-imposed manganese and glucose starvation. The study found that histidine kinase ArlS is necessary for activation of response regulator ArlR under both manganese and glucose-limited conditions.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalJournal of Bacteriology·TypeExperimental study·DateDec 6, 2021
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A new particulate saponin/TLR agonist vaccine adjuvant has been shown to alter lymph flow and modulate adaptive immunity. This study demonstrates the potential of this ingredient as a more effective vaccine booster.
SourceLa Jolla Institute for Immunology·JournalScience Immunology·TypeExperimental study·DateDec 3, 2021
Researchers found that macrophages play a central role in COVID-19-related respiratory failure, leading to fibroproliferative ARDS and prolonged ventilation. Extensive tissue damage and scar tissue formation are characteristic of severe lung failure.
SourceCharité - Universitätsmedizin Berlin·JournalCell·DateDec 2, 2021
A recent study published in PLOS Pathogens found that the COVID-19 Delta variant may have a reduced ability to be neutralized by vaccines. The researchers analyzed serum samples from vaccinated individuals and found that the Delta variant was more effective at evading vaccine-induced immunity than other variants, such as Beta and Alpha.
SourcePLOS·JournalPLOS Pathogens·TypeExperimental study·DateDec 2, 2021
A study by Imperial College London found that the first SARS-CoV-2 spike protein encountered through vaccination or infection influences subsequent immune responses to current and future variants. This 'immune imprinting' affects the rate of decay of protection and impacts antibody levels over time.
SourceImperial College London·JournalScience·TypeObservational study·DateDec 2, 2021
Scientists discovered that fungal endophytes convert chitin to chitosan, a natural plant defense activator, to evade host defense. This conversion enables the fungus to live in symbiotic association with grasses, protecting them from biotic and abiotic stresses.
SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·TypeExperimental study·DateDec 1, 2021
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A Canadian study found that delaying the second dose of an mRNA COVID-19 vaccine produces a stronger immune response, which could inform international vaccination strategies. This longer dose interval strategy enables early access to first doses and ensures better protection with the two-dose series.
SourceUniversity of British Columbia·JournalClinical Infectious Diseases·TypeObservational study·DateDec 1, 2021
A recent review article describes a class of viruses known as oncolytic viruses, which have the remarkable ability to target and destroy cancer cells. Researchers are exploring these viruses for cancer therapy, with some showing promising results in stimulating an immune response against cancer.
SourceArizona State University·JournalCancers·TypeLiterature review·DateNov 30, 2021
Antibodies that mimic the SARS-CoV-2 virus may explain lingering symptoms of long-haul COVID-19 and rare vaccine side effects like allergic reactions and blood-clotting. This theory, based on classic immunological concepts, suggests a cascade of immune responses that can lead to adverse effects.
SourceUniversity of California - Davis Health·JournalNew England Journal of Medicine·DateNov 24, 2021
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Previous antibody responses to harmless coronaviruses contribute to SARS-CoV-2 immunity, reducing infection severity and hospitalization rates. Researchers found that people with strong immune responses to other human coronaviruses have some protection against SARS-CoV-2 infection.
SourceUniversity of Zurich·JournalNature Communications·TypeExperimental study·DateNov 22, 2021
People taking immunosuppressants, especially TNF inhibitors, have a weaker antibody response to COVID-19 vaccines. A third dose can drive antibody levels back up, but the duration is unknown.
SourceWashU Medicine·JournalMed·TypeExperimental study·DateNov 19, 2021
A study found that individuals under 65 had higher antibody levels than those over 65, with women outperforming men. However, by six months post-vaccination, antibody levels dropped significantly for everyone in the study group.
SourceTexas Biomedical Research Institute·JournalJournal of Medical Biochemistry·DateNov 19, 2021
A novel gene therapy has shown sustained expression of clotting factor VIII, leading to a reduction or complete elimination of bleeding events in patients with hemophilia A. The trial demonstrated improved production of coagulation factor VIII over prolonged periods.
SourceChildren's Hospital of Philadelphia·JournalNew England Journal of Medicine·DateNov 17, 2021
A researcher at MUSC's Hollings Cancer Center is developing 'living drugs' by precision-engineering CAR Tregs to treat autoimmune diseases. The CAR Tregs can delay or reduce damaging inflammation, offering a potential solution for conditions like Type 1 diabetes.
SourceMedical University of South Carolina·JournalFrontiers in Immunology·DateNov 16, 2021
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study by Montefiore Einstein Cancer Center investigators found that a COVID-19 booster shot helps most cancer patients with no immune response after two-dose vaccination, significantly increasing antibody levels. The study also shows that all cancer patients benefit from vaccination, particularly those with blood cancer.
SourceAlbert Einstein College of Medicine·JournalCancer Cell·TypeObservational study·DateNov 16, 2021
A new study from the University of Georgia found that vaccination results in a more robust immune response than natural infection. Even with waning antibodies, vaccinated individuals still have protective immunity against severe disease and hospitalization.
SourceUniversity of Georgia·JournalFrontiers in Immunology·DateNov 16, 2021
Research suggests that obesity triggers inflammation, leading to an increase in myeloid-derived suppressor cells, which break down bone tissue. This can result in gum disease and tooth loss. The study found a significant link between high-fat diets and increased osteoclasts and alveolar bone destruction.
SourceUniversity at Buffalo·JournalJournal of Dental Research·DateNov 12, 2021
A multi-center study assesses medicinal mushrooms and Chinese herbs for therapeutic benefit in treating acute COVID-19 infection. The MACH-19 trial evaluates the safety and feasibility of two investigational compounds, one in capsule form and another as a Chinese herbal formula.
Researchers discovered inhibiting or genetically deleting the MTHFD2 enzyme reduced disease severity in various inflammatory disease models. This suggests that MTHFD2 function is important for immune cell regulation, particularly for T cell subsets involved in inflammation.
SourceVanderbilt University Medical Center·JournalImmunity·TypeExperimental study·DateNov 11, 2021
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers found that geriatric cotton rats given ibuprofen cleared RSV more quickly than those without the drug. Ibuprofen improved immune response by lowering aging-related inflammation, suggesting a potential role for the drug in providing lasting immunity against RSV.
SourceOhio State University·JournalVirology·DateNov 9, 2021
Researchers discovered a new biomarker, inactive AMPK (lo-P-AMPK), that may predict immune evasion in lung cancer. The finding could enable better personalized care for lung cancer patients by identifying those most likely to benefit from immunotherapies.
SourceUniversity of Helsinki·JournalClinical Cancer Research·DateNov 4, 2021
Recent research highlights microglia's involvement in Alzheimer's development and progression. A better understanding of microglial dysfunction may help explore signs and mechanisms of the disease, as well as enable microglia as a potential therapeutic target.
A study of 21 mothers found that those infected with SARS-CoV-2 during pregnancy had a varied immune response in their newborns, resulting in some infants developing antibodies and others not.
SourceJAMA Network·JournalJAMA Network Open·DateNov 3, 2021
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A new viral disease caused by Tomato brown rugose fruit virus (ToBRFV) has emerged, threatening global tomato production. ToBRFV overcomes the durable Tm-2² resistance gene, which had remained unbroken for over half a century.
SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·TypeExperimental study·DateNov 2, 2021
Researchers are developing a transformative technology called Multiscale Intelligent Convergence (MusIC) to map the complexity of T cells and identify attributes essential for patient benefit. The goal is to create more reliable biomanufacturing of T cell infusion products and engineering potent immune cells.
Researchers aim to predict and contain the spread of SCTLD by tracking coral immune responses. The study will examine which factors contribute to a successful immune response, where corals can recover and survive.
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers identified two nanobodies that specifically target and stabilize the tetrameric form of SARS-CoV-2 non-structural protein Nsp9, potentially repressing viral replication. These findings suggest a new antiviral strategy for diagnosis and treatment against COVID-19.
SourceNew York University·JournalAdvanced Biology·TypeExperimental study·DateOct 27, 2021
Researchers have identified a link between certain gut microbiome molecules and the immune system protein P-gp, which plays a critical role in gut inflammation. The study suggests that supporting a healthy balance of microbes in the gut may help regulate P-gp expression and prevent chronic inflammation.
SourceUniversity of Bath·JournalMicrobiome·TypeExperimental study·DateOct 26, 2021
A study published in International Journal of Molecular Sciences found that the Sputnik-V COVID vaccine elicits both robust antibody and T-cell responses. The research suggests that long-term immunity is possible, supporting the effectiveness of the vaccine against local virus variants.
SourceKazan Federal University·JournalInternational Journal of Molecular Sciences·TypeObservational study·DateOct 26, 2021
Researchers discovered that a lower dose of the first shot, followed by a full-dose booster, significantly improved SARS-CoV-2 vaccine potency in mice. This approach, which involves an extended prime-boost interval, may lead to more robust and durable immune responses.
SourceNorthwestern University·JournalScience Immunology·DateOct 25, 2021
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
New study reveals that blocking interleukin-23 is more effective than targeting both interleukin-23 and interleukin-12 in treating psoriasis. Interleukin-12, previously thought to contribute to the disease, actually protects against it by maintaining normal skin cell function.
SourceUniversity of Zurich·JournalScience Immunology·TypeExperimental study·DateOct 22, 2021
Scientists at Einstein College of Medicine have successfully suppressed HIV infections in mice using a novel treatment strategy that boosts the immune system's CD8+ T cells. The therapy, known as synTac, selectively targets HIV-infected T cells, eliminating them from the body and offering a potential path to a functional cure for HIV.
SourceAlbert Einstein College of Medicine·JournalJournal of Clinical Investigation·DateOct 21, 2021
A COVID vaccine booster dose increased levels of neutralizing antibodies against all known SARS-CoV-2 variants of concern. The boost was sustained for at least eight weeks and generated high-level protection against severe disease, suggesting a strong immune memory response and potentially longer lasting immunity.
SourceNIH/National Institute of Allergy and Infectious Diseases·JournalScience·DateOct 21, 2021
A study found that over half of double-vaccinated blood cancer patients have poor immune responses to COVID-19. Despite being vaccinated, these patients remain vulnerable to severe infection and are urged to continue wearing masks and maintaining social distancing.
SourceKing's College London·JournalCancer Cell·DateOct 21, 2021
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A new study from Karolinska Institutet finds that two vaccine doses increase antibody levels in the airways after COVID-19, while a second dose after recovery also boosts levels. The results highlight the importance of completing vaccination with a second dose to achieve optimal immune responses and reduce transmission.
SourceKarolinska Institutet·JournalJCI Insight·DateOct 20, 2021
Patients with multiple myeloma often mount a poor antibody response to COVID-19 vaccines and have a weak T cell response, underscoring the need for booster vaccination and safety precautions. Researchers found that these patients are at high risk of severe COVID-19 infection.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalCancer Cell·DateOct 18, 2021
A study by Northwestern University scientists has shown that coronavirus vaccines and prior infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines.
SourceNorthwestern University·JournalJournal of Clinical Investigation·DateOct 15, 2021
A new hydrogel treatment kills drug-resistant bacteria, including MRSA, and induces the expression of naturally-existing antimicrobial peptides in human skin cells. The gel is non-toxic, biodegradable, and scalable.
SourceKTH, Royal Institute of Technology·JournalJournal of the American Chemical Society·TypeExperimental study·DateOct 14, 2021
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers found that optimizing energy metabolism through autophagy can improve the immune system response in HIV-affected cells, providing a potential therapeutic approach. This metabolic optimization enables CD4 lymphocytes to better defend against HIV-1 by secreting IL-21, a key protein in defense against the virus.
SourceInstitut national de la recherche scientifique - INRS·JournalAutophagy·DateOct 14, 2021
Researchers discovered that RSV's NS1 protein alters immune gene expression to evade the immune response. The study provides crucial data for targeting NS1 in drug or vaccine development and may shed light on the link between RSV and asthma.
SourceWashU Medicine·JournalCell Reports·TypeExperimental study·DateOct 12, 2021
A University of Alberta-led study found that anemia can generate different immune responses in males versus females, making females more prone to infections. The research highlights the importance of considering sex as a variable in prevention, diagnostic, and therapeutic strategies for immune-related conditions.
SourceUniversity of Alberta Faculty of Medicine & Dentistry·JournalFrontiers in Immunology·DateOct 12, 2021
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Research at Florida Atlantic University found that green sea turtles in polluted environments have impaired immune systems, leading to increased disease susceptibility. The study suggests a positive feedback loop where pollution compromises immunity, making turtles more prone to Green Turtle Fibropapillomatosis.
SourceFlorida Atlantic University·JournalJournal of Wildlife Diseases·TypeExperimental study·DateOct 12, 2021
Researchers have developed a new sensor that can detect chemical changes in immune cells during the breakdown of pathogens. The breakthrough could lead to early diagnosis and better treatment of infectious diseases such as tuberculosis, which claims about 1.5 million lives annually.
SourceIndiana University·JournalAngewandte Chemie·TypeExperimental study·DateOct 8, 2021
Researchers analyzed fecal metagenomic DNA sequencing data to see if specific donor strains correlated with successful treatment outcomes. They found no correlation between donor strains and response to anti-PD-1 therapy in melanoma patients.
SourceUniversity of Alabama at Birmingham·JournalBMC Microbiology·TypeComputational simulation/modeling·DateOct 7, 2021
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers found that asymptomatic patients may not produce significant IgG antibodies, but rather a different kind of antibody count that can indicate disease severity. The study suggests using the ratio of these two counts as a marker to determine if a person has had COVID-19.
SourceSkolkovo Institute of Science and Technology (Skoltech)·JournalViruses·DateOct 7, 2021
A UCL-led research team has identified an anti-viral gene that increases the risk of both Alzheimer's disease and severe Covid-19. The study found that a specific variant of the OAS1 gene amplifies inflammation in the brain, highlighting the importance of the immune system in both conditions.
SourceUniversity College London·JournalBrain·TypeObservational study·DateOct 7, 2021
Cachexia is characterized by weight loss and muscle tissue shrinkage, driven by the immune system's response to chronic infections and diseases. Researchers from CeMM emphasize the need for more research into cachexia, highlighting the importance of interplay between the immune system and metabolism.
SourceCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences·JournalNature Reviews Immunology·TypeLiterature review·DateOct 5, 2021
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
University of Delaware chemical engineer Catherine Fromen aims to improve the delivery of therapeutic medicines to the body by studying how they interact with mucosal interfaces. Her research focuses on designing medicines that can overcome natural defenses in the lungs and gut, with potential applications for diseases such as lung can...
A study by University of Minnesota Medical School researchers found that fully vaccinated individuals with a previous SARS-CoV-2 infection have a stronger immune response, producing more memory B cells. This increased immune response may reduce the risk of breakthrough infections and potentially fewer doses needed for booster shots.
SourceUniversity of Minnesota Medical School·JournalCell Reports·DateOct 4, 2021
Research provides insights on immune responses of kidney transplant recipients following SARS-CoV-2 infection. The study found that production of IgG antibodies against the virus was delayed in these individuals, but their IgM and IgA responses were similar to those observed in non-transplant individuals.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateOct 1, 2021
Researchers found that cancer patients on chemotherapy had a lower immune response to the first two doses of the Pfizer-BioNTech COVID-19 vaccine. However, a third dose significantly boosted their immune response, reaching levels similar to those of healthy adults after two doses.
SourceUniversity of Arizona Health Sciences·JournalNature Medicine·TypeObservational study·DateOct 1, 2021
A study suggests that immunity from natural infection is short-lived and can wane over time, increasing the risk of reinfection. This could lead to a shift in the disease's progression from pandemic to endemic, making vaccination crucial for those who have been naturally infected.
SourceUniversity of North Carolina at Charlotte·JournalThe Lancet Microbe·DateOct 1, 2021
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Pediatric transplant recipients have a more robust immune response to COVID-19 vaccines, achieving higher antibody levels after two doses compared to adult counterparts. This study suggests that the standard two-dose regimen may be safe and effective in pediatric transplant recipients.
SourceJohns Hopkins Medicine·JournalAmerican Journal of Transplantation·DateSep 30, 2021
Researchers at the University at Buffalo have developed a new treatment that pairs essential proteins with lysophosphatidylserine to build immune tolerance and prevent antibody development, potentially treating autoimmune disorders and allergies.
SourceUniversity at Buffalo·JournalScientific Reports·DateSep 30, 2021
Studies found distinct patterns in nasal microbiota of individuals infected with SARS-CoV-2, with symptomatic patients showing reduced bacterial counts and increased presence of certain bacteria. The findings suggest that altered microbiota may impact immune response to the virus.
SourceMedical College of Georgia at Augusta University·JournalDiagnostics·DateSep 28, 2021
Researchers have developed a microneedle patch that delivers a COVID-19 DNA vaccine into the skin, causing strong immune responses in cells and mice. The patch can be stored at room temperature for over 30 days, making it an important tool for global COVID-19 vaccine distribution.
SourceAmerican Chemical Society·JournalACS Nano·DateSep 22, 2021
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers identified four immune markers that are elevated in SARS-CoV-2 patients in the early phase of infection but not in other viral infections. These findings could provide starting points for future therapeutic approaches and serve as comparative parameters for further studies on chronic COVID-19 forms.
SourceMedical University of Vienna·JournalFrontiers in Cellular and Infection Microbiology·DateSep 21, 2021
Researchers at the University of Illinois found that antibodies from people infected with the original COVID-19 strain do not effectively bind to newer variants. This has implications for vaccine efficacy and the design of possible boosters.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalNature Communications·DateSep 17, 2021
Researchers found that patients with MS receiving aCD20 treatment generated robust CD4 and CD8 T cell responses to the COVID-19 vaccination. The study measured both antibody and T cell responses in 20 patients with MS who were undergoing aCD20 treatment, compared to those in a group of healthy controls.
SourceUniversity of Pennsylvania School of Medicine·JournalNature Medicine·TypeRandomized controlled/clinical trial·DateSep 16, 2021
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
MIT researchers have found that vaccinating against certain cancer proteins can boost the overall T cell response and help to shrink tumors in mice. The study identifies specific neoantigens that, when targeted with a vaccine, can reawaken dormant T cell populations and lead to tumor regression.
SourceMassachusetts Institute of Technology·JournalCell·DateSep 16, 2021