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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

How does Tourette syndrome differ by sex?

A study published in Neurology found that female individuals with Tourette syndrome are less likely to be diagnosed, take longer to receive a diagnosis, and are diagnosed at an older age than males. The study also showed that symptoms started earlier in females with persistent motor or vocal tic disorder.

Predicting the chaos in Tourette Syndrome tics

Researchers have replicated and expanded on previous work to show that tics associated with Tourette syndrome have a fractal pattern, which can predict disease severity. This discovery could lead to a diagnostic tool for doctors to analyze tic patterns and diagnose patients with Tourette's

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How do tics develop?

A team of researchers from Charité – Universitätsmedizin Berlin has identified a neural network that generates tics, which could lead to improved treatment of people with Tourette syndrome. The study found that targeting this network via deep brain stimulation can alleviate symptoms in patients.

Can strep throat make tics worse in kids?

A study published in Neurology found that strep throat exposure was associated with an increase of about 20% in ADHD symptoms of hyperactivity and impulsiveness in children with chronic tic disorders. However, researchers did not find a link between strep exposure and worsening tics or symptoms of OCD.

An oral splint that can reduce Tourette syndrome tics

Researchers at Osaka University developed an oral device that effectively reduces motor and vocal tics in Tourette syndrome patients. The study found that the oral splint improved tic symptoms for both children and adults, with long-lasting effects.

Yale study uses real-time fMRI to treat Tourette Syndrome

A Yale study has trained adolescents with Tourette Syndrome to control their tics through real-time fMRI, achieving significant symptom reductions. The technique, called rt-fMRI-NF, involves monitoring brain activity in real time and adjusting it towards healthier patterns.

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Tics are common in famous boys choir

A new study found that 35% of young singers in an elite choir exhibited tics during a performance. This discovery may indicate a relation between ticcing and exceptional motor skills, potentially leading to a reevaluation of the perception of tics as a disorder.

Brain's role in Tourette tics simulated in new computational model

A new computational model simulates the role of the brain in Tourette syndrome, suggesting that motor tics arise from interactions between multiple brain areas. The model predicts how dysfunctions in neural circuits can lead to an increased number of tics, which could aid in identifying new treatment targets.

Brain chemical aids tic control in Tourette Syndrome, say researchers

GABA's role in dampening hyperactivity has led researchers to believe that increased production during adolescence improves symptoms for the majority of people with TS. This finding could offer a new approach to treatments targeting GABA levels in brain areas controlling motor function.

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Therapy affects the brain of people with Tourette syndrome

A study by researchers at the University of Montreal found that cognitive behavioral therapy can alter brain function in people with Tourette syndrome, reducing tics and improving brain activity. The therapy helped normalize brain activity in areas affected by the disorder.

Brain chemical potential new hope in controlling Tourette Syndrome tics

A study by University of Nottingham researchers found that higher levels of GABA in the supplementary motor area (SMA) help dampen down hyperactivity, allowing stronger signals to produce movement. This could lead to targeted approaches controlling tics using transcranial direct-current stimulation (tdcs).

Researchers uncover mechanism controlling Tourette syndrome tics

Scientists at the University of Nottingham have discovered a mechanism controlling tics in children with Tourette Syndrome. The study found that brain changes can alter excitability ahead of voluntary movements, suggesting a potential therapy to help young people overcome tics.

Behavioral intervention can reduce tics in adults with Tourette syndrome

A comprehensive behavioral therapy program has been shown to be effective in reducing tic severity in adults with Tourette syndrome. The study found that 38% of participants who received the treatment showed significant symptom improvement, compared to 6% of those receiving a control treatment.

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Almost 17 percent of Spanish children suffer tics

A new study published in Pediatric Neurology reveals that tics are a common disorder affecting approximately 16.86% of schoolchildren in Spain, with boys being more frequently affected than girls. The study found that while severe tics were previously thought to be rare, most cases are actually mild and have no functional impact.

Tourette Syndrome: non-drug therapy to reduce tics

A new study found that cognitive-behavioral therapy can reduce tics and brain activity in patients with Tourette syndrome, potentially leading to improved treatment options. The therapy was shown to have a measurable impact on brain activity linked to symptom improvement.

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New imaging technique reveals structural changes in Tourette's

Researchers used magnetization transfer imaging to visualize alterations in cerebral architecture of Tourette's patients and found correlations with symptom severity. They identified changes in the frontal lobe that may be responsible for the syndrome's pathology.

Children with Tourette's quicker at certain mental grammar skills

A study found that children with Tourette's syndrome are quicker at processing certain mental grammar skills, including rule-governed language tasks. They showed superior performance compared to typically developing children in producing grammatically correct past tense forms.

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Increased cognitive control in Tourette's syndrome

Researchers found that individuals with Tourette's syndrome make fewer error responses than neurologically normal peers, while responding just as fast to task demands, suggesting a compensatory change in cognitive control. This study challenges the widely held view that TS results from a failure of cognitive control mechanisms.

Grant will fund study of tics and Tourette syndrome

A four-year study will investigate the effectiveness of two behavioral interventions for adults with Tourette syndrome, with a focus on tic severity. The study complements an existing research program that explores similar treatments in children, funded by NIH.

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Treatments reduce strep-triggered symptoms of OCD and tics in some children

Researchers found that plasma exchange and IVIG relieve neuropsychiatric symptoms in children with tics and obsessive-compulsive disorder, with symptom improvements lasting up to a year. The study suggests these treatments may be effective for a subgroup of children with strep-triggered disorders, but not all cases.

New research on Tourette's syndrome

Research suggests Tourette's syndrome is not a simple motor disorder, but rather a condition affecting the brain's circuits that control planning and decision making. The study found that individuals with Tourette's can anticipate and adjust to their tics, indicating intentional movement.