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Cyclin D1 expression in penile cancer

Researchers found cyclin D1 expression in patients with penile cancer (PC) is associated with clinical and histopathological features. Patients with cyclin D1 expression had lower disease-free survival compared to the cyclin D1-negative group.

SourceImpact Journals LLC·JournalOncotarget·TypeObservational study·DateMay 15, 2024

In the evolution of walking, the hip bone connected to the rib bones

A new reconstruction of the 375-million-year-old fossil fish Tiktaalik reveals that its ribs likely attached to its pelvis, enabling support of the body and potentially leading to the evolution of walking. This discovery provides insights into the major evolutionary transition from fish to four-limbed vertebrates.

SourcePenn State·JournalProceedings of the National Academy of Sciences·DateApr 5, 2024

Pusan National University researchers reveal how diabetes weakens gum defense

Researchers from Pusan National University discovered a link between diabetes and periodontitis, showing pro-inflammatory cytokines rise in classical monocytes. The study highlights the systemic impact of these conditions on immune regulation and suggests a potential therapeutic target to reduce diabetes risk.

SourcePusan National University·JournalClinical and Translational Medicine·TypeExperimental study·DateFeb 15, 2024

Ready, set, go: New study shows how marathon running affects different foot muscles

A new study found that marathon running causes significant damage to extrinsic foot muscles, while intrinsic muscles are less affected. The research suggests that marathon runners can take steps to prevent injuries by prioritizing recovery and muscle fatigue management.

SourceShibaura Institute of Technology·JournalScandinavian Journal of Medicine and Science in Sports·TypeObservational study·DateMay 23, 2023

Sparse, small, but diverse neural connections help make perception reliable, efficient

Researchers mapped every thalamic synapse on 15 neurons in layer 2/3 of the visual cortex in mice and found that despite being weak and sparse, they are reliable and efficient representatives of information. The diversity of thalamic inputs underlies these advantages, allowing a small population of neurons to assemble the overall picture.

SourcePicower Institute at MIT·JournalNature Neuroscience·TypeExperimental study·DateFeb 2, 2023

“Unlocking” sarcopenic obesity: A review in portal hypertension & cirrhosis provides clarity on key aspects of disease impact and treatment

Researchers from Tianjin Medical University General Hospital review sarcopenic obesity's impact on liver disease, including nonalcoholic fatty liver disease and cirrhosis. The study aims to clarify the pathogenesis of sarcopenic obesity and identify potential therapeutic avenues.

SourceCactus Communications·JournalPortal Hypertension & Cirrhosis·TypeLiterature review·DateJul 6, 2022

Chinese Medical Journal review explores the role of macrophages in the progression of acute kidney injury to chronic kidney disease

A recent review article highlights the crucial role of macrophages in the progression from acute kidney injury (AKI) to chronic kidney disease (CKD). The study suggests that targeting specific signaling pathways and altering macrophage activation can prevent renal fibrosis and CKD. Therapeutic strategies such as clodronate liposomes an...

SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateJun 20, 2022

Under arrest: Using nanofibers to stop brain tumor cells from spreading

A team of researchers from Japan has developed a platform using nanofibers to capture and control the migration of brain tumor cells, including glioblastoma multiforme. The study found that varying fiber densities can slow or speed up cell movement, leading to the creation of 'cell traps' that can restrict tumor cell growth.

SourceUniversity of Fukui·JournalACS Applied Bio Materials·TypeExperimental study·DateOct 21, 2021

Revealing the secrets of ground beetle wing casings

A team from The University of Tsukuba used microscopy techniques to analyze the microstructure of the ground beetle's wing casing, revealing a unique helical structure that creates optical effects. This finding has significant implications for the development of new biomimetic materials with enhanced performance.

SourceUniversity of Tsukuba·JournalMicron·DateOct 5, 2021

Contrary to expectations, study finds primate neurons have fewer synapses than mice in visual cortex

Researchers at University of Chicago and Argonne National Laboratory found that primate neurons receive two to five times fewer excitatory and inhibitory synaptic connections than similar mouse neurons. The study suggests that metabolic costs may drive larger neural networks to be sparser, as seen in primates versus mouse neurons.

SourceUniversity of Chicago Medical Center·JournalCell Reports·DateSep 14, 2021

Now how did that get up there?

Researchers discovered three phases of growth that explain how cetaceans shift their nasal passage from a parallel to an angled orientation. This finding provides insight into the developmental process and could inform our understanding of cetacean evolution.

SourceUniversity of Washington·JournalJournal of Anatomy·TypeExperimental study·DateAug 5, 2021

Elsevier donates original drawings of the Pernkopf Anatomy Atlas to the MedUni Vienna

The Medical University of Vienna has received the original drawings and materials of the famous Pernkopf Atlas of Anatomy from Elsevier, along with funding for digitization and cataloguing. The donation supports historical reappraisal of the atlas's creation, which used models from executed victims of Nazi justice.

SourceMedical University of Vienna·JournalAnnals of Anatomy - Anatomischer Anzeiger·DateFeb 23, 2021

New study: The kitchen-counter diet

A new study found that keeping serving dishes off the table can lead to a reduction in food consumption, with participants eating 20% fewer calories. The strategy can also be used to encourage healthier food choices, such as choosing fruits and vegetables over processed snacks.