Articles tagged with Eye
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The Journal of Ocular Pharmacology and Therapeutics presents novel therapeutic approaches for treating uveitis, including cyclosporine, topical ganciclovir, and regulatory T cell therapy. These advances aim to improve treatment outcomes and quality of life for patients with autoimmune uveitis.
Scientists at the University of Birmingham have developed a painless method to deliver anti-VEGF drugs to the eye, using a cell-penetrating peptide. This innovation has the potential to revolutionize the treatment of age-related macular degeneration (AMD), reducing adverse outcomes and healthcare costs.
A study by Massachusetts Eye and Ear researchers found that oral promethazine temporarily worsened vestibular perception thresholds by 31 percent. This increase in thresholds could lead to poorer balance performance and a higher risk of falling.
Researchers analyzed 24,000 retinal exams to develop a new screening schedule for people with type 1 diabetes. The findings suggest that adjusting the frequency of eye screenings based on risk could lead to lower costs and quicker diagnosis and treatment of advanced retinopathy.
Researchers at Case Western Reserve University discovered a self-renewing mechanism to help retina sense light using biochemically manipulated vitamin A. This mechanism could lead to improved therapeutics for treating people with vision impairment and other nerve cell disorders.
Earl Smith's research seeks to determine how visual experience affects refractive development and explore new pharmaceutical approaches to eliminate myopia. The goal is to slow the progression of nearsightedness in children, addressing a growing global epidemic that affects over two billion people.
Deep-sea squids have developed unique eyes to spot two different sources of light: ambient sunlight and bioluminescent flashes. The large eye is adapted for gazing upwards, searching for shadows, while the small eye scans downwards for bioluminescence.
A study found a 30-fold increase in eye injuries linked to laundry detergent pods among preschool-aged children in the US between 2012 and 2015. The number of chemical burns associated with these devices rose from 12 instances in 2012 to 480 in 2015.
This review explores the potential of nanoparticle drug delivery systems to improve solubility, permeability, and stability of ophthalmic drugs. The development of these systems may offer a solution to the limitations of traditional topically administered formulations.
A survey of 393 hospital neonatal intensive care units found only 56% believe there are enough ophthalmologists to screen and treat retinopathy of prematurity. Screening can be done with telemedicine, but only 21% of respondents used retinal imaging devices, with half being unsure about its safety.
A recent study published in Frontiers in Aging Neuroscience found that physical exercise can help preserve adult visual plasticity in mice and restore it after a stroke. This suggests that exercise may be used as a preventive or therapeutic approach to aid recovery after a cortical stroke.
A new study found that vestibular thresholds double every 10 years above 40, correlating strongly with poorer balance test results and increased fall risk. Vestibular dysfunction is estimated to cause up to 152,000 American deaths each year, making it a leading cause of death.
A study reveals that neurons in the human eye work together to correct errors and improve visual signal accuracy. The research used a mathematical model to analyze retinal ganglion cell activity and found that collective signals are more reliable than individual cell signals.
A national five-year clinical trial will evaluate new treatment protocols for herpes zoster ophthalmicus, a form of shingles affecting the eye. The trial aims to reduce complications and preserve vision with longer-term suppressive antiviral medication.
Scientists at University of Oxford discovered that ducklings have two separate memory banks for visual information, which can cause internal conflicts. The findings shed light on how birds' brains work, highlighting the differences between avian and mammalian brains.
Researchers recommend a new eye pressure test to check for high eye fluid pressure after cataract surgery, which can cause swelling and vision loss. The test has been shown to reduce the risk of cystoid macular edema by 2.5-4 times.
A study published in JAMA Ophthalmology estimates that approximately 30,000 individuals per year report to US emergency departments with sports-related eye injuries. The majority of these cases involve males playing basketball or baseball, with the latter leading to significant blowout fractures and impaired vision.
A study found that internal astigmatism remains stable over time, contradicting the theory that the lens adapts to compensate for irregular eye shapes. The researchers analyzed 367 individuals with myopia and compared their data to 204 subjects without myopia.
A study by the University of Michigan's Kellogg Eye Center found that low-income children are less likely to be diagnosed with strabismus, a condition that can lead to permanent vision loss if left untreated. The study highlights the importance of ensuring access to eye care professionals and necessary services for all children.
Research by Johns Hopkins Bloomberg School of Public Health highlights the need to educate the public about preventable chemical eye burns in young children. The study found that one- and two-year-olds are at the greatest risk, with injuries most commonly occurring at home and among those in lower-income households.
Researchers link vitamin A metabolism to eye fibrosis, finding that retinoic acid triggers fibroblast signaling promoting scarring. Inhibiting aldehyde dehydrogenase may prevent ocular fibrosis.
Scientists at Hokkaido University measured eye pressure in sleeping patients with obstructive sleep apnea syndrome for the first time, discovering an unexpected correlation between the two conditions. This study sheds light on the potential mechanisms underlying glaucoma development in patients with OSAS.
A new technique developed by Disney Research can capture the crucial details of the eyes with just a single facial scan, producing highly realistic eye reconstructions. The parametric model enables flexible manipulation of the captured data to simulate emotions and fatigue.
Researchers at the University of New South Wales have developed a new eye test that can detect glaucoma four years earlier than current techniques. The patented method involves patients looking at small dots of light of specially chosen size and light intensity, identifying blind spots in the eye and early loss of peripheral vision.
A study found that routine eye exams lead to a change in vision prescription or other changes in care for over half of asymptomatic patients. The study also showed that older patients and those with longer intervals between visits were more likely to experience significant changes.
Research at ASM Microbe meeting reveals a new way bacteria can cause dramatic changes in human cells, leading to contact lens wear complications and inflammation. The study identifies key genes responsible for bleb formation, which may lead to novel therapies to prevent infection-associated inflammation.
Researchers have developed a medicated silicone ring that slowly releases medication over 6 months, potentially lowering the risk of vision loss among seniors with glaucoma. The device reduced eye pressure by about 20% in patients compared to traditional daily drops.
Despite concerns, leading eye specialists find no evidence to suggest lasers pointed at airplane cockpits damage pilots' eyesight. However, the dazzle and distraction from such incidents could prove disastrous during critical moments like landing.
The USC Roski Eye Institute's largest Chinese American eye study found a higher percentage (85 percent) of neovascular or 'wet' AMD among Chinese Americans compared to other ethnic groups. The study also revealed that participants with diabetes were three times more likely to experience significant visual impairment.
Researchers at Stanford University developed a machine to mimic the surface of the eye, allowing for systematic testing of tear film behavior on contact lens surfaces. This innovation could lead to more comfortable contact lenses that protect users from painful dry eye symptoms.
Researchers found a maximum reduction of 52.4% in dry-eye symptoms using the repurposed drug, with some patients reporting complete resolution of symptoms. The treatment has antiangiogenic effects and offers distinct advantages over existing surgical removal methods.
The study, funded by the National Eye Institute, identified FOXC1, TXNRD2, and ATXN2 as contributing genes to primary open-angle glaucoma. Variations in these genes may lead to reduced mitochondrial protection, increasing optic nerve cell death.
Researchers developed a portable sensor, OcuCheck, that uses graphene and ascorbate oxidase to detect vitamin C levels in ocular fluids. The device can rapidly determine the extent of eye injuries in various settings, including rural areas with limited access to ophthalmologists.
A study by the University of South Carolina team found that larger eye size in Daphnia results in an average clutch size increase of one egg beyond the average six eggs. The research team measured the effect of variation in body size, demonstrating that eye size has a greater impact on reproductive success.
The American Academy of Ophthalmology's IRIS Registry has revealed new information on rare complications following common eye procedures. Analysis shows no significant difference in endophthalmitis rates among three anti-VEGF treatments, but slightly higher rates in eyes with combined cataract surgery and anterior vitrectomy.
Researchers found that low-dose atropine eye drops significantly slowed myopia progression in children, with a 50% reduction compared to untreated children. The medication is safe for use in children age 6-12 for up to five years and may be an effective treatment in the fight against global nearsightedness.
Research identifies falls as the leading cause of eye injuries, accounting for over 8,425 hospitalizations, with serious ocular trauma injuries being expensive and preventable. The median cost of treating eye injuries increased by 62%, from $12,430 to $20,116, between 2002 and 2011.
Scientists at UC San Diego School of Medicine have elucidated a genetic interaction between SIX6 and p16INK4a that may prove key to the development and progression of glaucoma. Inhibiting p16INK4a expression could offer a new therapeutic approach for the disease, which is currently treated by lowering intraocular pressure.
The September special issue of Optometry and Vision Science presents significant strides in managing patients with dry eye symptoms. Key findings include new treatments such as omega-3 supplements and heat therapy, as well as emerging approaches to diagnosis and management.
Researchers found that the brain coordinates vision loss in glaucoma patients, with a 'Jigsaw Effect' where two puzzle pieces fit together. This suggests that the brain optimizes vision in the face of glaucoma's destruction of sight, opening up new areas of research for neuroprotective therapies.
Scientists capture subtle eyelid motions and create plausible folding and stretching in areas not directly captured during data collection. The method improves photorealistic actors for films by accurately determining the location of wrinkles and predicting their change based on eye region history.
Researchers discovered human eyes can distinguish between thin films of different thickness by observing color differences, achieving precision beyond normal human vision. This ability rivals techniques like ellipsometry, which measure minute thicknesses, and could be used as a quick check by experienced technicians.
Research suggests differences in oil-secreting glands and dermis thickness contribute to wrinkle formation. The study, published in Clinical Anatomy, found shallower wrinkles on the forehead compared to the outer eye area.
A new study in Liberia will investigate the long-term health consequences of Ebola virus disease (EVD) in survivors, determining if they develop immunity that protects them from future infection. The study will also assess whether previously EVD-infected individuals can transmit infection to close contacts and sexual partners.
A new computerized vision-screening test, the Jaeb Visual Acuity Screener (JVAS), has been developed to identify children with subnormal visual acuity. The test uses a set testing algorithm to minimize subjective tester bias and provides simple pass/fail results for four age groups.
Researchers identified a rare genetic mutation in the RBP4 protein that causes severe vitamin A deficiency and eye deformities. The mutation creates a functional 'double-whammy' by blocking both the transport of retinol to the developing embryo and the cell surface receptor for RBP4, leading to birth defects.
Researchers discovered a genetic basis for congenital eye malformations, caused by mutations in the RBP4 protein that transports vitamin A. The mutated proteins fail to transport retinol and block cell surface receptors, leading to severe retinol deficiency and birth defects.
A new study reveals a direct correlation between seasonal allergens and dry eye cases, with both conditions peaking in April. Dry eye can significantly impact quality of life, affecting millions in the US annually.
A new virtual reality testing environment provides a more realistic assessment of balance control in glaucoma patients. The study found that patients with glaucoma made balance adjustments 30-40% more pronounced than healthy subjects, highlighting the need for preventative measures.
A new study by Mass Eye and Ear surgeons found that professional singers experience no impairment in their voices after thyroid surgery using a neural monitoring system. The research showed 100% return to performance rate and mean time to performance was 2.26 months, with vocal fatigue being the most affected parameter.
A team of UH College of Optometry researchers aims to improve the vision of individuals with Down syndrome using computer-simulated prescribing strategies. The study, funded by the National Eye Institute, hopes to demonstrate improved visual acuity with new prescription methods that consider optical distortions in the eyes.
The National Expert Panel recommends annual vision health screening between age 36 months and before 72 months, with specific tests and training guidelines. The screenings aim to detect refractive errors, amblyopia, and strabismus, ensuring prompt diagnosis and referral to eye care professionals.
The Monash Vision Group has received a significant boost in funding for its Bionic Eye project, which aims to restore vision to millions globally. With $3 million in philanthropic donations, the project is now on track for human trials next year and could change tens of thousands of lives.
Researchers at Ohio State University created a video game training program that improves vision in people with lazy eyes and poor depth perception. The 'push-pull' method, using games like Pac-Man, stimulates both eyes equally to counter the common use of eye patches on dominant eyes.
A new study published in JAMA Ophthalmology found that telemedicine screening detected diabetic retinopathy in approximately 21.7% of the participants, highlighting its potential as a critical tool for patients with diabetes who face barriers to accessing regular eye care.
Researchers have identified new properties in microbes causing conjunctivitis, enabling the bacterium to stick to and damage the eye surface. The discovery may lead to the development of a new vaccine to prevent this infection.
A study of 4,379 participants found that having AMD in one eye increases the risk of developing AMD in the other eye, with more severe disease progressing faster. The researchers tracked AMD severity in both eyes over a 20-year period and found a strong correlation between the two eyes.
A new device called a punctum plug has been shown to be effective at reducing pain and inflammation following cataract surgery. The implant delivers the correct amount of postoperative medication, potentially solving issues of poor patient compliance with eye drops.
The University of Pittsburgh will lead a multidisciplinary consortium to explore strategies for whole-eye transplantation, with the goal of restoring vision in patients with traumatic or degenerative eye damage. The project aims to overcome challenges related to immune rejection and optic nerve regeneration.
Researchers at Northwestern University identify a critical chemical signaling pathway for the healthy functioning of Schlemm's canal, a key factor in developing glaucoma. They are now developing an eye drop that activates regrowth of the clogged vessel to lower pressure and restore normal drainage.