Articles tagged with Eye
A comprehensive study investigates the metabolism of four drugs in rabbit eyes, revealing different enzyme profiles from liver metabolism. The findings provide valuable information for advancing ophthalmic drug development.
The fossil of Callichimaera perplexa boasts remarkably large eyes that grow throughout development, unlike most crab species. Its exceptional vision suggests it was a highly visual, swimming predator.
A recent study investigated the progression of nearsightedness in nearly 700 young adults, aged 20-28. The findings indicate a significant increase in myopia among this age group, with a substantial impact on their daily lives and vision health.
Scientists have identified a crucial mechanism for Rhodopsin production in fruit flies, which may lead to a better understanding of retinitis pigmentosa and vision loss. The study reveals that the EMC protein complex is essential for the proper folding and insertion of Xport-A, a key chaperone of Rhodopsin.
Researchers created a disease map of genes involved in eye disorders, shedding light on how individual cells respond to external factors like injury. The study paves the way for regenerative medicine and cell replacement therapies for eye diseases.
A study of nationally representative survey data found that U.S. adults 50 and older with visual impairment are at higher risk for substance use or disorders compared to those without visual impairment. The analysis highlights the need for increased attention to substance use prevention and treatment among this vulnerable population.
A study to investigate stem cell therapy as a potential treatment for glaucoma, the world's second leading cause of blindness, has received $6.7M in NEI funding. The research team will explore ways to make stem cell-derived neurons survive and integrate into the eye.
Researchers have discovered a protein interaction that helps guide cells from the eye to a tiny midbrain processing hub during brain development. The absence of this beacon molecule, called nephronectin, leads to improper visual layer formation and hunting difficulties in mice.
Researchers developed a new protein treatment that prevents glaucoma from forming in mice and reduces pressure in the eyes. The study provides new targets for therapies and aims to develop an injectable treatment for patients.
University of Illinois Chicago researchers discovered a function of mammalian target of rapamycin complex 2 in an antiviral defense mechanism, limiting HSV-1 virus infection through rapid activation of antiviral immunity. The protein complex protects the host by preventing encephalitis and possible death due to HSV-1 infection.
Researchers from the University of Bonn have found that reading ability is a crucial indicator of functional loss in people with geographic atrophy, a late form of age-related macular degeneration. Reading speed and performance are essential for measuring everyday functional impairment.
A recent study found disparities in the use of telemedicine for ophthalmic care during the COVID-19 pandemic. These disparities highlight varying levels of access to and utilization of this technology in different populations.
Researchers at University of Illinois Chicago found a potential direct connection between neurodegenerative diseases, such as Alzheimer's disease, amyotrophic lateral sclerosis (ALS), glaucoma, and herpesvirus. The study suggests OPTN protein restricts HSV-1 virus spread in cells.
A randomized clinical trial found that students who received eye exams and glasses through a school-based vision program showed improved reading scores and academic achievement over one year. However, these positive effects were not sustained at two years after the program ended.
A study reveals that birds' eye size reflects their environment, diet, and behavior, providing insights into conservation efforts. The research suggests that larger eyes are associated with closer proximity to the equator and foraging habits near the forest floor.
A study by Inselspital and RetinAI uses AI to predict anti-VEGF treatment demand for patients with AMD, RVO, and DME. The model achieved high accuracy in predicting treatment need, even at the initial visit or before the first injection.
Researchers analyzed inner ear anatomy in extinct and living species to understand dinosaur sensory biology and behavior. The studies found clear patterns relating the shape of the semi-circular canal and cochlea to movement ability and hearing high-frequency sound.
University of Rochester researchers developed a novel technology using freeform optics and metasurfaces to deliver high-quality images with socially acceptable optics. The metaform component gathers visible light rays from all directions and redirects them directly into the human eye, achieving a significant improvement in image quality.
A new study by Tokyo Medical and Dental University clinicians reveals that horizontal transmission is responsible for HTLV-1 uveitis, a severe eye inflammation. The patient was treated with corticosteroids, showing promise in managing the condition, but highlighting the need to consider infection route in diagnosis and treatment.
A team of international researchers has shown that the network of nerves connecting eyes to brains evolved at least 450 million years ago in ancient fish, predating animals living on land. This discovery challenges existing theories and has implications for future health research.
A large-scale genetic study has identified 50 new genes associated with human eye color, significantly expanding the current understanding of this complex trait. These findings will help improve diagnosis and treatment of eye diseases such as pigmentary glaucoma and ocular albinism.
A new study found that dry eye disease significantly impacts visual function, daily activities, and work productivity. It also reveals a link between dry eye disease and increased anxiety, depression, arthritis, hearing loss, and irritable bowel disease.
Rapidly rising levels of sight loss are largely due to untreated ocular conditions, affecting hundreds of millions globally. A new study highlights the need for standard terminology and robust definitions to measure non-visually impairing eye diseases.
Researchers at the University of Birmingham have developed a method to measure intraocular pressure using soundwaves, which could help detect glaucoma earlier. This non-invasive technique uses a smartphone to scan people's eyes, prompting early diagnosis and treatment to prevent blindness.
Researchers analyzed genes in over 34,000 people with glaucoma and found 44 new genetic variants that may lead to new treatment targets. The study's findings aim to improve screening and diagnosis of glaucoma, as well as develop new treatments for this incurable eye disease.
A new commission report calls for eye care to be included in mainstream health services and development policies to achieve Universal Health Coverage and the 2030 SDGs. Improving eye health can have immediate benefits for individuals and nations, including economic gains of $AUD 530 billion a year.
Researchers at UIC aim to develop an antibody-based eye drop to treat dry eye and ocular surface disease caused by inflammatory and immune system disorders. The new treatment, which uses pooled human immune globulins, is expected to be particularly helpful for patients with immune-related dry eyes.
A recent study assessed the increase in pediatric cases of alcohol-based hand sanitizer eye exposure during the COVID-19 pandemic. The severity and management of ocular lesions were also evaluated.
A case of accidental hand sanitizer contact with the eyes resulted in severe ocular injury in one child. The authors describe two cases of such accidents and highlight the importance of proper hand hygiene practices to prevent such incidents.
Children who undergo cataract surgery as infants have a 22% risk of developing glaucoma by age 10. Lifelong monitoring is crucial to preventing vision loss due to increased eye pressure and optic nerve damage.
A new device, ECaBox, will resuscitate eyes from deceased body donors for clinical research purposes. The device will maintain the eye's temperature and pH levels while providing cells with oxygen and nutrients.
A new study uses next-generation sequencing to analyze genetic diversity of fish eye parasites, revealing complex life cycles and diverse habitats. The research also sheds light on the impact of parasites on fish behavior and immunity.
Researchers at Texas A\(M University have created a therapeutic derived from turmeric that reduces ocular inflammation in dogs with uveitis. The treatment bypasses intestinal and ocular barriers for improved absorption, offering a safer alternative to current medications.
The researchers created a lightweight eye mask called Chesma with two kinds of fabric electrodes to track electro-oculography and cardiac signals. The mask can be integrated into various garments and tested for performance after multiple washings.
Researchers identified a gene responsible for eye loss in cavefish, revealing its connection to a human vascular disease. The gene, cystathionine beta-synthase 'a' (cbsa), prevents blood flow to developing eyes, leading to withered eyes in blind fish.
Ocular scientists provide evidence-based guidance for practitioners and patients on safe use of contact lenses during COVID-19 pandemic, emphasizing importance of good hand hygiene, proper lens care, and temporary lens removal when ill. Experts also debunk rumors about glasses/spectacles providing protection against COVID-19.
Researchers at the University of Tyumen developed biomimetic optics that mimic human eye functions, offering excellent adaptation to changing conditions and miniature sizes. The new optics has advantages over traditional technologies, enabling wider range of functional characteristics.
Researchers at Flinders University have developed a new method to measure myopia, using OCT to identify irregularities in the eye's shape. This approach could lead to more effective monitoring and prevention of vision loss, as high myopia is expected to become the leading cause of blindness worldwide by 2050.
Researchers at the University of South Florida have discovered a novel feedback pathway from the brain to the eye that modulates eye pressure. This breakthrough finding may lead to new treatments for glaucoma by exploiting the modulatory mechanisms of the drainage control system.
HDR images offer a wider dynamic range of luminance, simulating human eye adaptation to various lighting conditions. A new method stabilizes the camera response function while coupling colour channels, producing artefact-free results.
A 370-million-year-old tetrapod, Parmastega aelidae, had a skull resembling a crocodile with eyes above its head, indicating it could keep an eye on prey while swimming. It used slender needle-like teeth and elastic jaws to snatch prey before crushing it with massive fangs.
Researchers developed a new non-invasive optical imaging system to diagnose and treat dry eye disease. The Tear Film Imager images layers of the tear film with speed and precision, providing nanometer-level insight into subtle changes in each layer.
A team of researchers is developing a data-driven computer model to diagnose and treat strabismus, a prevalent condition affecting 18 million people in the US. The model will use clinical information from MRI scans, surgical procedures, and patient outcomes to improve treatment options.
New optical security features use a two-piece metamaterial system to create difficult-to-replicate optical phenomena, making it harder to counterfeit money or intercept secure information. The approach offers improved forgery protection and can be used for various applications, including banknotes and identification cards.
Scleral pigmentation plays a role in eye morphology across great apes, with varying levels of contrast between irises and sclerae among species. The study suggests that some nonhuman great apes may use gaze as a social cue, similar to humans.
Scientists are working on a new method to detect glaucoma by analyzing the protein profile in eye fluid. They compare this profile with clinical data, including images of optic nerve damage, to identify a 'proteomic signature' for glaucoma. The goal is to develop a reliable diagnostic tool and monitor patients' progress.
Researchers found retinal vascular tortuosity, a microvascular abnormality, is associated with PAH and pulmonary vascular remodeling. The study suggests the eye may provide valuable information about pulmonary circulation health.
A small study published in the British Journal of Sports Medicine suggests that doubles badminton players are at greatest risk of potentially serious eye injuries during matches. Protective eye wear is highly recommended for all competitors to prevent such injuries, which can cause permanent vision loss and even blindness.
Researchers detected vascular changes in the human eye using an infrared camera, providing a new potential biomarker for identifying individuals at high risk of progressing to Alzheimer's. The study aims to explore the correlation between retinal capillaries and other brain biomarkers.
Researchers at Vanderbilt University have made significant findings on how the brain processes visual information from both eyes. Contrary to previous Nobel Prize-winning research, they discovered that the brain combines dual signals in milliseconds, not later stages of processing.
A new study published in the Journal of Glaucoma found that mindful meditation practice significantly lowers intraocular pressure, reducing stress-related biomarkers and improving quality-of-life. Meditation also positively influences other indicators, such as reduced cortisol levels and increased brain-derived neurotrophic factors.
A study by Massachusetts Eye and Ear found that astronauts or pilots with higher vestibular thresholds are more likely to become disoriented during flight. The researchers also found a strong correlation between lower vestibular thresholds and improved manual control performance.
The American Academy of Ophthalmology is honoring distinguished ophthalmologists like Steven T. Charles, M.D., for their scientific contributions to preventing blindness and restoring sight worldwide. Other notable recipients include David Heiden, M.D., and William L. White, M.D., who have made significant impacts through humanitarian ...
Researchers have developed a new approach to see-through displays for augmented reality smart glasses. The design projects images onto the eye using photons and holographic optical elements to form letters and words.
New study finds that eye dominance and visual acuity are governed by separate areas of the brain, making it possible to correct one without affecting the other. Researchers can now address acuity directly, bypassing normal eye dominance restoration.
A study published in JAMA Ophthalmology found that US pediatric eye injuries decreased by 26.1% from 2006 to 2014. Most of these injuries had a low risk of causing permanent vision loss. In contrast, sports and household-related injuries increased, while motor vehicle crashes, gun-related incidents, and chemical burns declined.
A new study led by the NIH identified roles for over two dozen genes shared with humans, many linked to human eye disorders, in causing cavefish blindness. Epigenetic regulation mechanisms have been found to play a key role in this process.
Researchers found guppies rapidly turn their eyes black to warn rivals, making their eyes more conspicuous as an honest signal of aggression. This behavior is seen in larger guppies dominating smaller ones, but not the other way around.
Cavefish have higher levels of DNA methyltransferase DNMT3B in developing eyes, leading to epigenetic suppression of eye development genes. This process differs from genetic mutations, which are permanent changes in the DNA code.
The study found that pupils dilate before reported inspiration, predicting subsequent inspiration. This discovery may lead to externally monitoring and controlling memory retrieval in the future.