Researchers discovered that non-hibernating pikas alter their gut microbiota to increase urea nitrogen salvaging, maintaining protein homeostasis during winter. This adaptation helps the animals cope with the scarcity of dietary protein during the cold season.
Researchers discovered hibernator-specific DNA regions near the FTO locus that regulate metabolism, allowing hibernators to pack on fat reserves before hibernation. These findings could lead to treatments for human metabolic disorders by tuning up or down gene activity like an orchestra conductor fine-tunes music volume.
Researchers found that hibernating lemurs' telomeres got longer, contrary to the usual decrease with age, suggesting a potential way to reverse cellular aging. This study, conducted at Duke University and the University of California, San Francisco, provides insights into the mechanisms behind lemur's remarkable survival strategy.
A study found that wild hedgehogs in the same area have varying hibernation patterns, with some starting as early as mid-September and others not entering until December. This flexibility could help them adapt to changing environmental conditions.
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Researchers at Hokkaido University have identified a key gene, glutathione peroxidase 4 (Gpx4), that enables Syrian hamsters to survive extreme cold by limiting cellular damage. The discovery could lead to new treatments for human health, such as improving organ preservation and using hypothermia as a therapeutic tool.
A recent study challenges the notion that domestication is the primary driver of reduced brain size in domesticated animals. The study found that the reduction in relative brain size in domesticated dogs is not an evolutionary singularity among Canids, as other ecological and evolutionary pressures can also drive such changes.
ICU patients with contractile weakness of the diaphragm due to mechanical ventilation develop a state of hibernation, where myosin protein is trapped in an energy-saving state. This compromises diaphragm strength and independent breathing, leading to difficulties in weaning from the ventilator. Researchers have found a potential lead f...
A new species of fossil snake, Hibernophis breithaupti, has been discovered in Wyoming, shedding light on the origin and diversification of boas and pythons. The discovery provides important new information on the evolution of small burrowing boas, specifically rubber boas.
A new study found that magnesium levels in sandhoppers increase during cold weather, slowing their activity. In deeper sleep, magnesium levels can more than double, putting the sandhopper into a torpid state and allowing it to conserve energy.
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A study on the largest colony of bats in Catalonia found that global warming is altering their physiology, behavior, and migration patterns. Bats are accumulating less fat reserves, shortening their hibernation periods, and leaving their winter shelters sooner, which could impact their reproduction and conservation.
The study reveals changes in motor protein structure and energy consumption during hibernation, highlighting key differences between large and small hibernators. Myosin plays a crucial role in non-shivering thermogenesis, with smaller mammals experiencing increased ATP consumption at lower temperatures.
A recent study found that polar bears, closely observed by scientists, struggled to maintain weight when their preferred seal prey was out of reach during longer ice-free seasons. Despite trying various strategies, including resting and foraging, nearly all the bears lost weight rapidly, highlighting their vulnerability to climate change.
A genetic study found that grizzly bears' energy production follows a daily pattern even during hibernation, with a blunted amplitude and shifted peak. This suggests that the circadian rhythm helps bears conserve energy while still maintaining some metabolic function.
Researchers have found that mouse stem cells mimic their parent animals' cold resistance, generating energy differently at low temperatures. This discovery opens up new avenues for studying organ preservation and human hibernation using in vitro models.
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Researchers at CU Anschutz Medical Campus identify fructose as a central conduit to obesity and diseases. Fructose works differently than other nutrients by lowering active energy, stimulating food intake and leading to weight gain.
A multidisciplinary team led by Hong Chen successfully induced a torpor-like state in mice using ultrasound, which also worked on rats. The researchers found that stimulating the hypothalamus preoptic area with ultrasound activated neurons and induced changes in body temperature and metabolism, allowing for the preservation of energy.
Researchers found that female arctic ground squirrels are emerging from hibernation earlier every year due to warmer temperatures, potentially leading to healthier litters and higher survival rates. This change is accompanied by differences in male hibernation patterns, which may have negative consequences for the food web.
A large-scale genomic study of 240 mammal species reveals previously uncharacterized regulatory elements in the human genome, linked to disease risks and distinctive traits. The research provides insights into the evolutionary development of mammalian genomes and their potential applications in medical research.
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A study by an international research team has found a mechanism that occurs in brown bears and paraplegics, preventing the formation of blood clots. The discovery could lead to new treatments for venous thromboembolism, a life-threatening condition.
A team of researchers at Aarhus University has discovered a protein that helps protect the body against blood clots in hibernating bears. The protein, HSP47, is found to be downregulated during winter months, allowing bears to avoid blood clots.
Research discovers that reduced levels of Hsp47 protein can prevent blood clots in humans, pigs, and bears, even when immobile for extended periods. The study's findings could lead to new medicines for people with inherited blood clotting disorders.
Scientists have used gene therapy to increase 'cold shock protein' levels in mice brains, protecting them against prion disease. The approach could lead to a safer treatment for acute brain injury and prevention of neurodegenerative diseases like Alzheimer's.
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Researchers found that hummingbirds can enter into deep or shallow torpor, and their ability to do so is tied to their evolutionary conquest of mountain habitats. Torpor duration varies depending on ambient temperature and physical condition.
The study successfully demonstrated hypothermia in a primate model using targeted neuronal manipulation. Monkeys showed increased heart rate, shivering, and locomotion to defend their body temperature, highlighting a complex thermoregulation mechanism.
Researchers found that coral microbiomes shed nutrient-loving and pathogen-associated microbes while increasing nitrogen-fixing microbes during dormancy. This restructuring helps maintain the coral's microbial community structure.
Inducing a hibernation-like state in mice using Q neuron activation has been shown to protect kidneys from oxygen deprivation and avoid harmful side effects. This technique could lead to new methods of performing heart surgery with reduced organ damage.
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Scientists have found that synthetic torpor increases resistance to ionizing radiation, a major health risk for human space exploration. The research uses artificially induced hibernation in rats and demonstrates biological effects suggesting enhanced radioprotection.
Researchers at MIT's Picower Institute suggest that Covid-19 patients in comas may enter a protective hibernation state to shield cells from oxygen scarcity. This hypothesis is supported by observations of cardiac arrest patients treated with hypothermia and the painted turtle, which also enters a similar state during prolonged anoxia.
Researchers at Washington State University identified eight proteins that regulate insulin sensitivity and resistance in hibernating bears, similar to human genes. The discovery could lead to the development of treatments for human diabetes.
A new study reveals that European moles reduce their brains by 11% in winter and regrow them by 4% in summer to conserve energy. This phenomenon, known as Dehnel's phenomenon, is driven by cold conditions rather than food shortage alone.
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A UC researcher is using information technology to track and study the endangered little brown myotis bat species in Ohio. The team has established a summer roost at Clendening Marina, where they are collecting data on the population's size and trajectory.
New research from the University of Ottawa finds that climate change is waking bumblebees earlier from winter hibernation, putting the species at risk. The study found that this early emergence timing puts bees out of sync with their food sources, leading to smaller colonies and lower survival rates.
A study led by UMD researchers found that hibernating big brown bats experience slower epigenetic aging, with their biological clock extending by nearly a year. The study established the link between hibernation and longer lifespans in small mammals.
A new collaboration between UW Oshkosh and Fauna Bio aims to translate animal disease resistance into human treatments. The partnership will enable researchers to study emerging animal models, such as the 13-lined ground squirrel, to develop novel therapeutic programs.
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Researchers found that yellow-bellied marmot's biological aging stalls during hibernation, with epigenetic changes playing a key role. The study suggests that hibernation may be a natural way to slow aging and promote longevity in other mammals.
A new study reveals that microbes in the guts of hibernating ground squirrels play a crucial role in recycling nutrients and maintaining muscle mass. The discovery could have significant implications for humans with muscle-wasting disorders and astronauts on extended space voyages.
Research found that bats can adapt to diverse climates by finding similar roosting conditions, but those with high water loss are more heavily impacted by white-nose syndrome. This study highlights the importance of understanding bat hibernation patterns for conservation efforts.
A study by Osaka City University reveals that urban lighting and heat delay insect hibernation, allowing insects to enter hibernation up to 3 weeks later than in rural areas. The findings suggest that increased nighttime light and heat from urban areas interfere with the natural photoperiodism of insects.
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A new study finds that urbanization is causing many mammal species to grow bigger, contrary to Bergmann's Rule. The study analyzed over 140,000 measurements of body length and mass from North American mammals collected over 80 years.
A recent study published in the New Zealand Journal of Ecology found that alpine-based hedgehogs hibernate in the same areas they used in summer and do not migrate to lower elevations. This discovery suggests that hedgehogs are residents in these zones, rather than just visitors.
Pikas reduce their metabolism to conserve energy during harsh winters, resulting in a 30% decrease in daily energy expenditures. In areas with high yak populations, pikas exploit an easily accessible food source, yak feces, which may help explain their relatively abundant presence.
Researchers found that black bears provided a top-down buffering effect, helping to protect gray foxes from coyote competition for food and space. However, this 'bear shield' was only seasonal and disappeared during bear hibernation.
Duke Lemur Center successfully replicates wild hibernation conditions, revealing insights into metabolic disorders and aging. The study's findings have significant implications for human health, particularly in the development of new treatments for heart attacks and strokes.
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A Rutgers-led study found genetic differences between white-nose syndrome-killed and surviving little brown bat populations, suggesting rapid evolution to resist the disease. The study has significant implications for managing bat populations and may inform strategies for other diseases causing mass mortality.
Researchers found that European greater mouse-eared bats have sufficient baseline levels of key immune parameters to tolerate infection throughout hibernation. In contrast, North American bats frequently arouse from hibernation to trigger an immune response, leading to starvation and death.
Researchers found that omega-3 fatty acids in flaxseed and fish oil helped Arctic ground squirrels regulate their body temperature during hibernation, increasing brown adipose tissue. This discovery sheds light on how animals prepare for extreme cold temperatures.
A recent study found that bats infected with white-nose syndrome continue to roost in warm and deadly sites, leading to higher mortality rates. Researchers suggest that altering these sites may be crucial for conservation, but interventions must consider the complex physiology of bat species.
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Researchers discovered that Arctic ground squirrels recycle their body's own nutrients to survive during long, inactive winters. They convert free nitrogen into amino acids, allowing them to synthesize protein in vital tissues.
A long-term study found that common noctule bat migration patterns change over successive generations, with younger males leading the way in colonizing new hibernacula. This flexibility may enable the species to stay within ideal conditions for reproduction and rearing of young or hibernation.
Scientists discovered a hibernation-like state in 250-million-year-old Antarctic animal, Lystrosaurus. The fossils showed signs of stress and strain, similar to those found in modern animals experiencing torpor, suggesting a possible adaptation to cope with the extreme winter conditions.
Scientists have discovered a hibernation-like state in an ancient Antarctic animal, dating back 250 million years. The discovery indicates that torpor arose in vertebrates even before mammals and dinosaurs evolved.
Researchers at the University of Tsukuba and RIKEN in Japan have identified specific cells in the mouse brain that can trigger a hibernation-like state when activated. This discovery has significant implications for potential human hibernation applications, including medical uses such as emergency transport or critical care situations.
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Researchers at Harvard Medical School have identified a population of neurons in the hypothalamus that controls hibernation-like behavior in mice. Stimulating these neurons induces torpor, while blocking their activity disrupts natural torpor, offering insights into the neural mechanisms underlying this state.
A new study models the life cycle of cataclysmic binaries, confirming that observable novae are just a small fraction of these systems. The research shows that most binaries spend 90% of their lifetimes in a detached state, waiting to be detected.
A new study from the University of Michigan presents the first genetic evidence of resistance in some bats to white-nose syndrome, a deadly fungal disease that has decimated some North American bat populations. Genetic differences were found in genes associated with regulating arousal from hibernation and breakdown of fats.
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A team of scientists studied grizzly bears' muscles during hibernation and found that they produce non-essential amino acids, which can stimulate cell growth. This discovery could lead to the development of new methods to prevent and treat muscle atrophy in humans.
Scientists at University of Utah Health have discovered new genetic elements that could help control obesity and metabolic disorders. Hibernating mammals have evolved short non-coding DNA snippets near genes linked to obesity in humans.
A new study highlights the importance of building roosts for little brown bats' survival during maternity season. Researchers found that 84% of reproductive females roost in attics, while males prefer rock crevices or trees.
Researchers solved the domain structure of HPF from Staphylococcus aureus to understand its role in ribosome hibernation. The study identified key amino acid residues essential for protein function, opening doors to new compounds targeting stress proteins.
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Grizzly bears express a larger number of genes than any other species studied to cope with hibernation-induced metabolic stressors. They reverse the negative effects of fat accumulation by switching genes on and off based on the season.