Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
A 12-month study of 430 overweight men and women showed a significant weight loss of 11.6 kg with Xenical, with improvements in blood pressure, cholesterol levels, and waist circumference. The results demonstrate the efficacy of Xenical in a real-life clinical practice setting.
A recent study has found that low-calorie dieting raises ghrelin levels, while gastric bypass surgery sharply reduces them, making it a potential key to unlocking the secrets of successful weight loss. The research also suggests that this mechanism may be why gastric bypass surgery is often more effective than dieting.
Researchers at Duke University Medical Center investigated the impact of taste and smell deficits on cancer patients' weight loss and nutritional status. Adding flavor-enhancing powders derived from foods like cheese, bacon, garlic, and fruits showed promise in improving appetite and immune function.
A study presented at Nutrition Week showed that patients taking weight loss medication Xenical who enrolled in a support programme lost twice as much weight as those who did not (8.5kg vs 4kg). The two-way support improved patient satisfaction, with over 90% of patients worldwide satisfied with their treatment and level of weight loss.
Researchers found that patients taking Bupropion SR lost statistically significant more weight than those in the placebo group during a 24-week initial period. After 48 weeks, patients who received Bupropion SR continued to lose weight, with an average of 8.6% and 7.5% body weight loss.
A study published in the American Journal of Clinical Nutrition found that women who gained weight after weight loss had significantly lower energy expenditure due to physical inactivity. To match their initial weight, these individuals would need to engage in at least 80 minutes of moderate-intensity physical activity per day.
C75 blocks fatty acid synthase, a key enzyme in energy storage, to alter brain messengers regulating appetite. Lean mice quickly regain normal eating habits after treatment, while obese mice fail to recover.
The study, conducted in Olmsted County, Minnesota, found that only a small percentage of people utilize recommended approaches to weight loss. The efforts being undertaken by CardioVision 2020 aim to reduce cardiovascular disease burden through diet and exercise changes. Meanwhile, another study on breast cancer patients highlights the...
The Look AHEAD trial will examine the effects of a lifestyle intervention program on cardiovascular health in people with type 2 diabetes. The study, which began screening participants in July, aims to enroll 5,000 volunteers and follow them for up to 11.5 years.
A University of Michigan study tracked weight changes among over 10,000 adults for 13 years, finding that about 51% of men and 55% of women remained in the same weight category. The study also revealed a significant 'yo-yo diet effect,' with nearly one-fifth of children aged 2-12 being overweight or at risk.
New research presents preliminary results of a study on Xenical's effectiveness in promoting rapid and sustained weight loss. The medication has been shown to improve cardiovascular risk factors and maintain weight loss for up to two years, resulting in significant health benefits.
Researchers found that adding leptin to sibutramine increased weight loss in obese rats, as it prevented a decrease in leptin levels that normally occurs with weight loss. This study provides new clues on how to overcome the plateau effect and may lead to successful treatments for obesity.
A study published in Obesity Research found that bupropion, an antidepressant approved for depression and smoking cessation, is effective for long-term weight loss in obese women. Women who took bupropion combined with a 1,600-calorie diet lost significantly more weight than those on placebo, with sustained effects for up to two years.
A study found that 12% of girls aged 12-14 experienced binge-eating episodes, while 7% engaged in self-induced vomiting to lose weight. Researchers recommend screening for eating disturbances among girls with higher body mass indexes.
Researchers found that obese women who used weight loss medication MERIDIA in combination with a comprehensive lifestyle modification program lost an average of 24.4 pounds, compared to 8.4 pounds for those treated by medication alone. Lifestyle modification included diet and exercise, as well as weekly group sessions to plan meals and...
A study found that weight loss lowered high-normal blood pressure in overweight adults, but only a small percentage maintained substantial weight loss over three years. Another study discovered that scuba diving increases the risk of brain lesions due to decompression illnesses and heart abnormalities.
A recent study published in the American Journal of Clinical Nutrition found that a low-calorie diet can slow down metabolism, but when stopped, the metabolic rate returns to normal. Variations in resting metabolic rate do not predict weight regain, suggesting other factors are at play.
Women who repeatedly gain and lose weight, especially if obese, have lower HDL or
A study of 24 postmenopausal women found no significant differences in resting metabolic rate (RMR) between those who lost weight and a control group. Despite average weight loss of 13 kg, the subjects regained an average of 10.9 kg after energy balance was restored.
A new obesity treatment program has resulted in sustained weight loss for six years by developing two fundamental internal skills: self-nurturing and effective limit setting. Participants lost an average of 13 pounds in the first 12 weeks and continued to lose weight after treatment ended.
A new study finds that intense weight training exercises can increase strength in older men, similar to those in their 20s. Researchers also observed improvements in muscle tone, aerobic capacity, and cholesterol profiles.
Two human studies suggest CLA may help overweight individuals lose weight and fat, maintain weight loss, retain lean muscle mass, and control adult-onset diabetes. In one study, participants experienced a statistically significant reduction in body fat gain with no serious side effects.
A study published in the American Journal of Clinical Nutrition found that black women who lost weight through dieting had a significantly lower energy expenditure than white women. The researchers suggest that differences in body composition, including denser bones and more lean tissue in the limbs, may contribute to this disparity.
A new study suggests that Americans gain about a pound during the winter holiday season, which accumulates over time and contributes to obesity later in life. The researchers found that increasing physical activity may be an effective method for preventing weight gain during this high-risk time.
A recent NIH-funded study found that overweight breastfeeding mothers can safely lose weight through a balanced diet and regular exercise without harming their infants. The study showed an average weight loss of 5 kilograms in the intervention group, while the control group experienced variable results.
A recent study by Duke University researchers found that moderate exercise alone can improve cholesterol levels and reduce body fat in mildly obese people, regardless of weight loss. The study showed significant improvements in cardiovascular risk factors, including a decrease in LDL cholesterol and an increase in HDL cholesterol.
A UK study found that individuals who completed an intensive, very low calorie diet (VLCD) program maintained a significant weight loss of 23% or more for over five years. This is higher than the general rate of weight loss with modest programs, which averages 9%.
A six-year study found that elderly women who lose weight are nearly four times more likely to die than those who maintain their weight. Maintaining average BMI over the study period had the lowest death rate among participants.
A study by Brown University researchers found that overweight women who used home exercise equipment lost significantly more weight than those without the equipment, with an average of 16.3 pounds lost compared to 8.1 pounds. The equipment also helped participants maintain a higher level of exercise throughout the study.
A large-scale national study will investigate whether weight loss reduces cardiovascular disease and slows atherosclerosis progression in obese people with type 2 diabetes. The 7-year trial, funded by the National Institute of Diabetes and Digestive and Kidney Disorders, aims to enroll 6,000 participants.
Scientists at OHSU have discovered a mechanism in the brain that controls weight, named the adipostat, which acts as a fat thermostat. The discovery could lead to medications that help regulate patient weight and prevent excessive caloric intake.
A new study of over 300,000 people found that obesity significantly increases the risk of premature death by 5.9 and 6.4 years for men and women aged 40-50, respectively. Optimal weight remains the same across different age groups, with excess weight artificially adding years to real age.
A recent study found that low-fat diets combined with moderate exercise resulted in not only desired weight loss but also significant loss of bone mineral density. Women who participated in the study lost an average of 7 pounds, but also experienced twice as much bone loss as those who didn't modify their diets or exercise patterns.
Researchers at Washington University School of Medicine suggest that obesity drugs can improve long-term weight loss results when used in conjunction with lifestyle changes. Patients who have already made significant progress through behavioral programs may still benefit from medication to maintain their weight loss.
A meta-analysis of formerly obese individuals who lost weight found that their resting metabolic rate decreased, explaining why dieters struggle to maintain weight loss. This decrease in metabolism may be a key factor contributing to the difficulty in keeping excess weight off.
A pilot study at Duke University Medical Center found that bupropion SR combined with a 1,600-calorie diet resulted in significant weight loss among non-depressed women. The study showed a 6.21% weight loss in the treatment group compared to 1.56% in the placebo group.
A study published in the American Journal of Clinical Nutrition found that African American women who lost weight on reducing diets burned less resting energy expenditure than their white counterparts. This difference was significant and may contribute to the higher prevalence of obesity among Black women in the US.
A study of nearly 4,000 young adults found that smoking has a negligible effect on body weight, contrary to the tobacco industry's claims. Smoking cessation, however, is associated with significant long-term weight gain.
Researchers found that inexpensive signs can increase stair use by 4.8-7.2% among different age groups and racial demographics, with significant benefits for Caucasians but little impact on African Americans.
A study by Stanford University School of Medicine found that individuals dissatisfied with their bodies and those with a history of weight fluctuations face extreme difficulty losing weight. The research suggests that combining diet and exercise is crucial for success, emphasizing the importance of addressing both aspects.
The new guidelines provide a comprehensive framework for healthcare professionals to diagnose and treat overweight and obesity in adults. Key findings include the importance of assessing body mass index (BMI), waist circumference, and risk factors for diseases associated with obesity, as well as recommending calorie reduction, increase...
A comprehensive study published in the American Journal of Public Health found that weight loss, not weight gain, is associated with higher mortality rates in seniors. Women with a body mass index of 20 or lower had a significantly higher mortality rate than others.
A large study of 5,106 primary school students found that overweight children had higher blood pressure, total cholesterol, LDL cholesterol, and lower HDL cholesterol levels than their lighter peers. The study also showed that many more children became overweight over time than returned to a healthy weight.
A new study reveals that body fat is significantly associated with increased blood pressure, particularly in women. Researchers found that those who gained more fat over time also experienced higher increases in blood pressure.
A study of 975 older adults with hypertension found that about 40 percent maintained diet and exercise changes, enabling them to stop taking medication for high blood pressure. Participants who made moderate changes in body weight and salt intake showed impressive results, controlling blood pressure without medication.
The TONE study shows that weight loss and sodium reduction produce significant results in reducing the need for blood pressure medicine. Lifestyle interventions led to a 30% reduction in blood pressure medication use among participants.
A University of Florida study found that women who exercised at home lost more weight and maintained their progress longer than those in a group exercise program. The home-based workout group averaged over 25 pounds of weight loss, compared to 15 pounds for the group exercisers.
A new study by Dr. June Stevens of the University of North Carolina at Chapel Hill found that excess body weight increases the risk of death from heart disease and other causes up to late life, with optimal weight found at a body mass index (BMI) of 19-22 until age 75.
Researchers found that nearly 77% of participants reported a trigger event preceding their successful weight loss. The majority of participants made significant changes in their dietary intake and physical activity levels to achieve serious weight loss. On average, they expended calories equivalent to walking 28 miles per week.
A study published in the Proceedings of the National Academy of Sciences found that mice with resistance to leptin are more likely to become obese. The researchers used a novel technique called ICV infusion to deliver leptin directly into the brain, which resulted in significant weight loss and fat reduction in lean mice.
A study of 32 obese women found that shedding excess weight led to improved body image and increased sexual activity. However, the improvement was not statistically significant and the level of sexual activity remained below national averages.
Female patients with acute anorexia nervosa exhibit low plasma leptin concentrations, reflecting restricted energy intake. Leptin levels increase upon weight gain, but drop again after weight loss, suggesting a complex relationship between leptin regulation and weight fluctuations in these individuals.
A recent study by the University of Pennsylvania School of Medicine found that black women have lower resting metabolic rates than white women, making it harder to lose weight. This difference in metabolism was observed even after adjusting for weight and muscle mass.
A Cornell University nutritionist analyzed 40 studies on long-term use of the diet pill Redux and found that the benefits do not outweigh the risks. The amount of weight lost after one year is equivalent to a 62-calorie difference a day, roughly the amount burned by walking for half a hour.
A Johns Hopkins study found that declining testosterone levels in HIV-positive men can predict weight loss and increased risk of death. Researchers measured testosterone in 26 men and discovered a significant decline in hormone levels among those who experienced weight loss.