A new study estimates an 'eliciting dose' for peanut allergies, revealing that tiny amounts can trigger reactions in some individuals. The researchers found that exposure to 0.052 milligrams of peanut protein is likely to cause or elicit an allergic reaction in 1% of patients.
Researchers from Murdoch Children's Research Institute found a significant decrease in peanut allergy among infants after international infant feeding guidelines changed in 2016. The study also showed a rise in parents introducing peanut into their babies' diet since the guideline changes.
A Johns Hopkins Medicine study reveals that emotional stress promotes symptoms of genetic heart disease and worsens its progression. Physicians and patients are advised to focus on good mental health, in addition to exercise avoidance, to keep patients healthy.
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A new Northwestern University study found 2.9% of US adults have a current peanut allergy, with approximately one in five experiencing severe reactions each year. The study also revealed that patients who developed their peanut allergy after age 18 are less likely to report having an epinephrine auto-injector prescription.
Researchers are using plant breeding and genetic engineering to develop less allergenic varieties of wheat and peanuts. They focus on reducing gluten content in wheat and one specific protein that regulates gluten production, aiming to increase food options for people with allergies.
A six- to ten-week resistance training program significantly improved knee flexion peak torque and vastus lateralis thickness in older adults who received peanut protein supplementation, compared to those without. The study found that PP supplementation increased muscle strength and growth in untrained older individuals.
A new study published in the Journal of Allergy and Clinical Immunology: In Practice found that exposing children to small, regular doses of peanuts can reduce the risk of severe allergic reactions. Nearly 80% of preschoolers were able to eat a full serving of peanuts without reaction, protecting them from 99% of accidental exposures.
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Researchers create antioxidant-boosted milk chocolate by combining peanut skins and coffee waste with maltodextrin. The resulting confection has higher chemical antioxidant activity than most dark chocolates and is undetectable in flavor.
A new grant will fund the research, which aims to develop an effective and efficient cleaning method for peanut butter processing facilities. The technology has the potential to reduce cleaning time by nearly a week and minimize the risk of Salmonella contamination in peanut butter production.
A study published in JAMA Network Open found that only 30% of US pediatricians fully implement recommended practices for preventing peanut allergy, with common barriers including lack of clinic time and parental fear. The 2017 guidelines aim to introduce peanut-containing foods at 4-6 months to reduce prevalence.
Researchers at Massachusetts General Hospital have discovered a new marker for allergic diseases, sialic acid on IgE antibodies, which may improve diagnoses. The team also found that removing sialic acid from IgE enhances allergic reactions in animal models, paving the way for novel treatment strategies.
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Researchers found IgE-producing plasma cells abundant in the stomach and duodenum of patients with peanut allergy, highlighting a potential mechanism for severe allergies. The study suggests that targeted prevention of class switch recombination in the gut may be a promising treatment approach for severe peanut allergy.
A longitudinal study of children with persistent food allergies found those allergic to cow's milk were smaller and weighed less than their peers with peanut/tree nut allergies, persisting into early adolescence. The study suggests young adults with persistent cow's milk allergy may not reach full growth potential.
A study published in the Journal of Allergy and Clinical Immunology identified over 300 genes and 200 CpG sites associated with reaction severity. The research suggests that neutrophil-mediated immunity plays a prominent role in peanut allergy reactions, offering potential new targets for treatment.
Researchers have developed a novel vaccine that uses a virus-based platform to rewrite the body's natural response to peanut allergens, causing a non-allergic immune response. The vaccine has shown signs of success in mouse models and preliminary in vitro studies, paving the way for human trials.
Research found that introducing peanut and egg early to infants can reduce the risk of developing a food allergy. Despite low adherence to an introduction regime, the study showed that early introduction was effective in preventing food allergies in specific groups of infants.
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A technique identified T cells that react to peanut allergens by analyzing their RNA expression. The study could help guide researchers in developing new treatments for food allergies.
A new antibody treatment has shown promising results in a small pilot study, allowing participants with severe peanut allergies to eat a modest amount of peanut protein within 15 days. The treatment's effects lasted for up to 45 days, providing a potential breakthrough for food allergy treatments.
Oral food challenges (OFCs) are the most effective way to diagnose a food allergy, say two new studies. A child with atopic dermatitis and suspected peanut allergy passed an OFC despite prior skin testing results, while another boy who had removed peanuts from his diet after eczema flares developed anaphylaxis to peanut
Researchers at King's College London have found that immunotherapy for peanut allergy reduces sensitivity to peanuts, providing some protection against accidental reactions. However, the treatment does not cure allergies and can actually increase allergic reactions in some patients, highlighting the need for continued research.
A study found that desensitization from peanut oral immunotherapy can be maintained by continuing a modest dose of peanut protein, offering more protection against allergic reactions. Participants who passed food challenges had lower initial levels of antibodies and indicators of allergic activity in their blood.
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A new peanut allergy treatment, sublingual immunotherapy (SLIT), has shown effectiveness in protecting patients from severe allergic reactions. SLIT involves placing tiny amounts of peanut protein under the tongue, where it is absorbed immediately into the bloodstream, desensitizing the immune system to larger amounts of peanut protein.
Introducing peanut protein regularly can lower a baby's risk of developing a peanut allergy. Canadian Medical Association Journal recommends introducing peanut butter or powdered puff at home between 4-6 months for most babies.
Scientists have discovered two new species of 'tweezer-beaked hopping rats' that specialize in eating earthworms, showcasing the incredible biodiversity of the Philippines. The discovery highlights the importance of protecting mountainous forests, which provide unique habitats for these animals and other endemic species.
Researchers found two new species of 'tweezer-beaked hopping rats' in the Philippines, with distinctive features like long pointed noses and sturdy hind legs. The discovery highlights the country's incredible biodiversity and the importance of protecting mountainous forests where these unique species thrive.
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Children with severe eczema infected with Staphylococcus aureus are at a higher risk of developing peanut, egg, and milk allergies. The bacteria may reduce the chance of young infants gaining tolerance to peanut despite early consumption.
The study provides a reference framework for breeding and improvement of the peanut crop, revealing the origin of peanut in South America and genetic mechanisms that generated diversity. The team mapped the entire peanut genome, identifying key traits like seed size and disease resistance.
The study provides a detailed understanding of the peanut plant's genomic history and the molecular mechanisms underlying its growth and development. Researchers have identified potential leads for improving crop resilience to diseases and pests, including geographic origin information and DNA swapping patterns.
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A systematic review of 12 studies with over 1,000 patients found that peanut oral immunotherapy increases the risk and frequency of anaphylaxis and allergic reactions. Despite inducing desensitisation in the clinic, the treatment does not lead to improved quality of life for patients.
A new study published in the Journal of Allergy and Clinical Immunology: In Practice suggests that oral immunotherapy is safe for preschool-aged children with peanut allergies. Researchers followed 270 children who received oral immunotherapy and found that 90% reached the maintenance stage successfully.
Researchers identified two epitopes capable of eliciting strong allergic reactions in serum samples from all or nearly all patients, and engineered molecules to selectively bind to IgEs recognizing these epitopes. Treatment with the inhibitors inhibited over 80% of the allergic response to peanut extract in patients.
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Researchers at the University of Notre Dame have developed a novel inhibitor that selectively targets IgE and prevents allergic reactions to peanuts. The breakthrough finding has significant implications for treating severe peanut allergies, with up to 90% success rate in inhibiting an allergic response.
A multi-year observational study found that eating small amounts of peanut after immunotherapy can extend allergy treatment benefits and improve quality of life. The majority of participants continued regularly eating peanuts daily for up to eight years without any reactions from accidental ingestions.
A study funded by NIH found that a daily nutritional supplement can improve fetal growth and reduce stunted infants. The inexpensive supplement increased infant birth size by 31% and reduced small-for-gestational-age births by 22%.
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A study by Ohio State University researchers found that people's gaze influences their choices when faced with two visible options. The researchers used eye-tracking technology to show that attention amplifies a person's desire for chosen items, particularly those already liked.
A new peanut variety has been discovered to conserve water during droughts, allowing it to maintain a high yield as the soil dries out. By reducing transpiration earlier in the drought cycle, the plant saves water for later use, resulting in increased productivity.
Researchers developed a new oral immunotherapy drug, AR101, derived from peanut protein, to build tolerance in peanut allergy sufferers. The study found that more than two-thirds of participants taking the active drug could tolerate a dose of peanut protein equivalent to about two peanut kernels.
A new treatment has been shown to help people with peanut allergies build up a tolerance to the allergen, allowing them to consume small amounts without experiencing severe reactions. The study found that two-thirds of participants were able to tolerate the equivalent of two peanuts per day after nine to 12 months of treatment.
Researchers analyzed simulated children with peanut allergy and estimated value-based pricing for autoinjector devices. The analysis suggests a maximum price of $24 a year to protect against risk of death from anaphylaxis.
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Researchers have developed a sensitive new test to detect trace amounts of peanuts in foods using the peanuts' DNA. The new assay targets DNA from peanut chloroplasts, resulting in a detection limit of about 1 part per million.
The US Navy is developing a new type of coating that can repel various liquids and reduce friction drag on ships, potentially saving millions in fuel costs. Researchers have created an omniphobic coating that can be applied to multiple surfaces and withstand scratches and daily wear.
Scientists developed a new laboratory test to diagnose peanut allergies with high accuracy and safety. The mast activation test (MAT) measures biomarkers associated with allergic reactions and can detect peanut allergy in children as young as six months old.
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Researchers are working to identify biomarkers for food allergies, aiming to improve understanding of how children's immune systems react to certain foods. Current blood tests are only 30-55% specific, leaving room for further innovation in diagnostics and treatments.
Researchers developed a nasal spray vaccine that shifts the immune response toward peanut tolerance in mice with established allergies. The vaccine's nano-emulsion adjuvant promotes a strong infection-fighting response that suppresses allergic reactions.
Researchers have developed a vaccine that can redirect the immune response to prevent allergic symptoms, providing extended relief from peanut allergies. The study shows promise for potential therapy of allergies in humans and may lead to long-lasting suppression of food allergies.
A study of 191 children found that those with persistent cow's milk allergies had lower mean weight and height compared to kids with peanut or tree nut allergies. The growth deficits were more pronounced among school-aged kids, with differences remaining prominent in preadolescence.
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Researchers at Duke University Medical Center have developed an innovative approach to treat peanut allergies by retraining the immune system using nanoparticles. The study found that delivering molecules to the lymph nodes quells allergic reactions, providing long-lasting tolerance without repeated exposures.
Early introduction of peanuts into the diet may prevent the development of peanut allergy in high-risk infants. Oral immunotherapy is a promising approach to allergen desensitization for children with known peanut allergies, increasing threshold amounts before experiencing reactions by at least 25 times.
Researchers developed mathematical equations to calculate crop yields and optimize fertilizer use for sorghum-peanut intercropping. The study aims to improve profits and food production in West Africa, where millions of farmers face food security challenges.
A skin patch containing a high dose of peanut protein reduced peanut sensitivity in 50% of patients compared to placebo, warranting further investigation. The 250-μg peanut patch showed significant efficacy in treating peanut allergy, suggesting potential for safer and more effective treatment.
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A study published in the Journal of the American College of Cardiology found that eating regular variety of nuts, including peanuts and walnuts, was associated with a lower risk of cardiovascular disease. Participants who consumed five or more servings of nuts per week had a significant reduction in cardiovascular disease risk.
A breakthrough discovery has been made by suppressing the aflatoxin-producing fungus in groundnut, significantly improving food safety. The research, published in Plant Biotechnology Journal, has potential to contribute to food security in under-developed countries.
A new study suggests a significant increase in childhood peanut allergies in the US, with rates rising 21 percent since 2010. Nearly 2.5 percent of U.S. children may have an allergy to peanuts, and black children are disproportionately affected.
A recent study revealed that only 11 percent of pediatricians follow guidelines for introducing peanut-containing products to infants to prevent allergies. High-risk babies, those with egg allergy and/or severe eczema, are not being referred for testing prior to introduction.
Researchers have identified a new gene associated with peanut allergy, suggesting a role in general allergic predisposition. The study's findings suggest potential targets for predicting and managing food allergy treatments.
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Researchers have pinpointed a specific subset of immune cells, known as TH2 subset or type 2 "helper" T cells, which are central to allergies. The identified cells, dubbed TH2A, were found to produce multiple inflammatory signaling molecules and unique gene expression patterns that drive allergic responses.
Patients with stage III colon cancer who consumed two ounces or more of tree nuts per week had a 42% lower chance of cancer recurrence and 57% lower chance of death than those who did not eat nuts. This benefit was consistent across known factors that can influence cancer recurrence.
The National Institutes of Health has designated $42.7 million for the Consortium of Food Allergy Research (CoFAR) over seven years to continue evaluating new approaches to treat food allergy. CoFAR scientists are working on immunotherapy approaches to reduce immediate allergic symptoms and bring about long-term relief.
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A study published in the Journal of Nutrition found that eating peanuts with a meal can help prevent arterial stiffening and keep blood vessels healthy. The researchers observed a 32% reduction in triglyceride levels after peanut consumption compared to a control group.
A team of researchers has discovered a molecular mechanism that explains why allergies are less common in developing countries. They found that antibodies produced in response to a parasitic worm infection can prevent an allergic reaction when faced with novel substances like peanut protein.