Articles tagged with Peanuts
Researchers at Boston Children's Hospital found that fecal transplants from healthy donors reduced peanut allergy symptoms in some patients. The study suggests that the right bacteria can help restore tolerance to food through bile acid metabolites. Increased levels of immune regulatory cells also protected against allergic reactions.
Researchers at Mount Sinai will investigate biological mechanisms driving peanut allergy desensitization, identifying biomarkers for patient prediction and advancing personalized treatment strategies. The INROADS center aims to improve treatment outcomes and accessibility for patients with peanut allergy.
Researchers treated 75 children with peanut allergies using slow up-dosing and low maintenance dosing. After three years, 82% of the treatment group could eat at least 3.5 peanuts without an allergic reaction.
Researchers have produced complete genome sequences for six peanut varieties, identifying two candidate genes linked to oil content and seed size. These findings provide a comprehensive blueprint for future peanut breeding and improvement strategies.
A new study found that most parents are aware of the importance of introducing peanuts to babies early, but lack clarity on details. Researchers recommend a consistent and timely approach, starting with peanut-containing foods as soon as solids begin, and continued exposure twice a week.
A new study led by Northwestern University found that introducing peanut-containing foods to infants can cut peanut allergy risk by more than 80%. Pediatrician training and electronic health record prompts significantly improved adherence to guidelines, with guideline-based care seen in 84% of low-risk infants.
A randomized clinical trial shows that targeted educational and clinical decision-support tools improve pediatrician adherence to prevention guidelines, leading to higher rates of early peanut introduction. The intervention resulted in significantly higher guideline adherence among low-risk infants.
A Northwestern University study found that Zileuton nearly eliminated life-threatening allergic reactions to food allergens in mice by targeting a previously unknown gene called DPEP1. The discovery could lead to a new, simple pill-based treatment for food allergies.
A research team has discovered a native peanut Ubiquitin4 promoter (AhUBQ4) with strong transcriptional activity, driving robust gene expression in various tissues and conditions. The AhUBQ4 promoter also showed improved efficiency in CRISPR/Cas9 editing compared to foreign promoters like CaMV 35S.
Researchers identified crucial structural variations that determine seed size and weight in peanuts, paving the way for improved legume crops. A pangenome of peanut was assembled, serving as a fundamental resource for genetic enhancement.
The study shows that two-thirds of adults with severe peanut allergy can tolerate five peanuts without reacting after undergoing oral immunotherapy. The treatment improves quality of life and reduces fear of food, allowing participants to enjoy everyday situations without anxiety.
A new consensus report on anaphylaxis has been released, providing updated clinical criteria and guidelines for diagnosing and treating the condition. The report includes distinct infant findings to improve management in young children, addressing a significant burden on patients and caregivers worldwide.
A study published in The Journal of Immunology found that supplementing maternal diet with vitamin E during pregnancy can reduce the development of food allergy and anaphylaxis in newborn mice. This potential breakthrough could help address the alarming increase in peanut allergy among children.
Researchers report that eating increasingly higher doses of peanut butter enabled 100% of children with peanut allergy who initially tolerated half a peanut to consume three tablespoons without an allergic reaction. The therapy could potentially fulfill an unmet need for about half of children with peanut allergy, who already can toler...
A new study led by researchers at Mount Sinai Hospital found that children with high-threshold peanut allergy can be treated with a safe and effective approach, allowing them to tolerate larger doses of peanut butter. The treatment involves gradually increasing doses over 18 months, resulting in sustained unresponsiveness to peanuts fo...
Research from RIKEN Center for Integrative Medical Sciences found that infant gut bacteria are associated with food sensitivities and allergies, particularly to eggs. The study suggests that probiotic supplements, such as Bifidobacterium, may help prevent food allergies in at-risk infants.
Researchers from Brazil and Spain developed computer models to estimate crop maturity and yield using remote sensing technologies, increasing productivity and reducing CO2 emissions. They also created a system to estimate soil moisture levels with high accuracy, helping growers manage water usage more efficiently.
A new study found that exposure to higher levels of air pollution as a baby is associated with increased odds of developing a peanut allergy and having it persist throughout childhood. Policies aimed at tackling poor air quality could potentially reduce the development and persistence of peanut allergies, according to researchers.
A new test mimics allergic reactions in a test tube, showing higher diagnostic accuracy than standard tests for peanut allergy and potentially other allergies. The Hoxb8 Mast Cell Activation Test (Hoxb8 MAT) has been shown to have an exceptionally high diagnostic accuracy of 95% and leads to fewer false negative results.
The new consensus guidance outlines what NHS services need to offer Palforzia desensitization treatment at scale, regardless of patient location or background. The recommendations aim to equitably provide an actual treatment for peanut allergy, moving beyond avoidance and education.
Lynne McLandsborough's research offers a solution to the sticky sanitation issue in peanut butter and chocolate industries, improving food safety and reducing bacterial illness outbreaks. Her patent-pending method uses a water-in-oil emulsion to kill 99.9999% of Salmonella bacteria.
This study validates a two-stage process for producing polyhydroxyalkanoates (PHA) using peanut oil and propionate with Cupriavidus necator. The findings show that peanut oil is the most beneficial carbon source, leading to increased biomass and PHA production.
A new study found that feeding children peanut products regularly from infancy to age 5 reduced the rate of peanut allergy in adolescence. The results showed a 71% reduction in peanut allergy, even when children ate or avoided peanut products later on.
Australian researchers have identified biomarkers that can predict which children are likely to outgrow their peanut allergy. The study found that two-thirds of children with a peanut allergy remain allergic by age 10, but most who naturally outgrew their allergy did so by age six.
A monoclonal antibody, omalizumab, increased the tolerance threshold for multiple food allergens, allowing children to consume larger amounts without a reaction. The treatment showed significant benefits in reducing allergic reactions, particularly for peanut and egg, with potential protection against accidental exposure.
Scientists have created a new therapy using nanoparticles to target specific immune cells responsible for allergic responses. The approach, which combines an allergen with antibodies that selectively inhibit mast cells, has shown promising results in a mouse study, preventing allergic reactions without causing side effects.
Researchers have successfully used a specially formulated toothpaste for Oral Mucosal Immunotherapy (OMIT) to desensitize adults with peanut allergies. The study showed that 100% of participants consistently tolerated the highest dose without severe reactions, and 97% adhered to treatment.
A new study finds that people with antibodies to common foods like dairy and peanuts are at a higher risk of cardiovascular-related death. The research suggests that these subtle immune responses may lead to inflammation and contribute to heart disease over time.
A clinical trial found that Peanut SLIT is safe and effective in children aged 1-4 years, with over 80% tolerating peanuts without allergic symptoms after treatment. Remission of peanut allergy was also possible, with 63% maintaining protection three months after stopping the treatment.
A study published in PLOS ONE reveals that pre-Columbian Caribbean cultures consumed a wide variety of plants, including sweet potato, chili peppers, and domesticated tomatoes. The analysis also detected tobacco and cotton, challenging the traditional staple food narrative.
Researchers found that all 22 babies achieved a reduced sensitivity to peanuts after completing the treatment. After an oral food challenge, 91% of them could tolerate peanuts without triggering any allergic reactions.
A new study found that babies with food allergies are more likely to develop asthma and have reduced lung function by six years of age. Early life food allergy was associated with an increased risk of both conditions, even if the allergy resolved or persisted.
A new study from Northwestern University found that only 13% of US parents and caregivers are aware of the 2017 NIH guidelines recommending early peanut introduction to prevent peanut allergy. Despite this, more work is needed to educate families and clinicians about the guidelines.
A year-long immunotherapy through a skin patch safely desensitized toddlers with peanut allergy, lowering the risk of a severe allergic reaction from accidental exposure. Children who originally reacted to small amounts of peanuts were able to tolerate larger quantities after completing treatment.
A six-month study of 63 healthy young participants found significant improvements in vascular markers after consuming daily peanut products. The study suggests that peanuts' polyphenols have beneficial effects on cardiovascular health.
Scientists investigated whether patients allergic to legumes are also at risk from meat-free proteins made of other legumes. While most people won't experience a reaction, nearly all patients with bean allergies were sensitized to other legumes, and nearly a quarter of patients were sensitized to all legumes.
A comprehensive European allergy atlas has been compiled, revealing regional and climate-related differences in sensitisation to allergens. The study found varying sensitisation patterns across Europe, with certain regions having lower sensitivity to house dust mites and higher sensitivity to peanut and fruit allergens.
Scientists at Indiana University School of Medicine have developed a new treatment that blocks anaphylaxis caused by peanut allergies, potentially saving lives. The covalent heterobivalent inhibitor (cHBI) was tested in animal models and showed promise in preventing allergic reactions for over two weeks.
Researchers at the University of Notre Dame have successfully developed an allergen-specific inhibitor that prevents peanut allergic reactions in mice. The inhibitor effectively masks the immune system's ability to recognize the allergen, allowing it to fly under the radar without initiating a dangerous response.
A clinical trial found that boiling peanuts for up to 12 hours can desensitize children with peanut allergies. The therapy involved sequential doses of boiled and roasted peanuts, achieving high success rates in participants. While promising, the study's findings require confirmation in larger trials.
A phase 2 clinical trial using boiled peanuts followed by roasted peanuts showed promising results in desensitizing 80% of children with peanut allergies. Treatment-related adverse events were reported in 61% participants.
Researchers used big datasets to show that annual health care costs were significantly higher among children without allergist care for peanut allergy compared to those who received care. Care from an allergist resulted in lower total health care costs, saving $1,923 per child.
Researchers create polymeric micelles that deliver butyrate, a compound produced by healthy gut bacteria, to restore the gut's protective barrier and microbiome. The treatment prevents life-threatening anaphylactic responses in mice with peanut allergies.
A new study published in Applied and Environmental Microbiology suggests that oil formulations with food-grade organic acids can kill dried Salmonella on stainless steel surfaces. This approach has the potential to replace water-based cleaning methods, which promote microbial growth and are often challenging to use.
A new study found that consuming lightly salted peanuts twice a day before meals led to significant weight loss and improved blood pressure and fasting glucose levels. The peanut-enriched group experienced an extra 15 grams of protein, which may contribute to the findings.
A five-year collaboration aims to create high-yielding, low-input peanut lines with increased oil content for the renewable diesel industry. The project seeks to improve peanut varieties' adaptability to dryer climates and reduce carbon intensity in agricultural practices.
Scientists have created a membrane made from a waste by-product of vegetable oil manufacturing that can filter out heavy metals from contaminated water. The membrane uses proteins derived from peanut or sunflower oil production to attract and trap heavy metal ions, purifying water to international drinking standards.
A new study published in the Journal of Allergy and Clinical Immunology: In Practice found that infants under 12 months who undergo oral immunotherapy have a better safety profile compared to older preschoolers. The treatment, which involves gradually increasing exposure to peanut flour, is highly effective and safe for this age group.
Australian researchers have discovered specific gene networks rewired to drive peanut allergy remission through a combination treatment of probiotic and oral immunotherapy. This network reprogramming shuts down the allergic immune response responsible for causing food allergies.
A recent study published by the Murdoch Children's Research Institute found no significant association between caesarean birth and the development of food allergies in infants. The research involved over 2,000 infants and suggested that babies born via caesarean delivery are not at a higher risk of developing food allergies.
Researchers developed a microneedle treatment that increased desensitization rates to peanut allergy in mice, outperforming existing immunotherapy methods. The novel approach achieved significant results using lower doses of allergen, offering new hope for millions suffering from peanut allergy.
A new study found that serious allergic reactions to food among children have flattened since changes to Australian infant feeding guidelines. The research showed a slowing rate of increase in hospital admissions for food anaphylaxis among young children and teenagers, but overall rates remain high. Experts emphasize the need for effec...
Two new treatments have been found to induce peanut allergy remission in children, with about half achieving remission and experiencing significant improvements in quality of life. The combination treatment and oral immunotherapy alone were both highly effective, providing substantial benefits for children's health and well-being.
A clinical trial found that peanut oral immunotherapy desensitized most highly allergic children and induced remission in one-fifth. Younger children and those with lower levels of peanut-specific antibodies were more likely to achieve remission, with 71% of 1-year-olds experiencing remission.
A randomised controlled trial found that most young children treated with peanut immunotherapy achieved desensitisation after two and a half years of treatment, while one in five remained in remission. Younger children under one year old were more likely to achieve remission, suggesting early interventions may provide better outcomes.
Scientists have discovered a new layer of regulation in plant-microbe interactions using peanut studies. An antisense long-noncoding RNA, DONE40, was found to bind to a protein involved in epigenetic control, suggesting a conserved function across plants and animals.
A new study reveals that only 40% of parents received a recommendation to introduce peanut products by 11 months of age, despite the 2017 guidelines. The survey also found that most infants are at moderate- or low-risk for developing peanut allergies and can safely have peanut-containing foods introduced.
A study published in Clinical Nutrition Journal found that daily peanut consumption improved cognitive function and stress response in young and healthy individuals. The researchers discovered that bioactive compounds such as resveratrol and p-coumaric acid, as well as short-chain fatty acids, contributed to the health effects.
A study published in Stroke Journal Report found that eating 4-5 peanuts per day lowers the risk of ischemic stroke and cardiovascular disease among Japanese men and women. Peanuts are rich in heart-healthy nutrients that help reduce cardiovascular disease risk factors.
A study of consumers with food allergies found that less than half understood allergy information on food labels, attributing varying levels of comprehensibility assessments. Precautionary statements have little value for consumers and may lead to inappropriate dietary restrictions or risk-taking behavior.