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New consensus report on anaphylaxis: A major advancement in allergy care

A new consensus report on anaphylaxis has been released, providing updated clinical criteria and guidelines for diagnosing and treating the condition. The report includes distinct infant findings to improve management in young children, addressing a significant burden on patients and caregivers worldwide.

SourceCincinnati Children's Hospital Medical Center·JournalJournal of Allergy and Clinical Immunology·DateMar 4, 2025

Therapy helps peanut-allergic kids tolerate tablespoons of peanut butter

Researchers report that eating increasingly higher doses of peanut butter enabled 100% of children with peanut allergy who initially tolerated half a peanut to consume three tablespoons without an allergic reaction. The therapy could potentially fulfill an unmet need for about half of children with peanut allergy, who already can toler...

Eating gradually increasing doses of store-bought peanut butter enables children with high-threshold allergy to safely consume peanuts

A new study led by researchers at Mount Sinai Hospital found that children with high-threshold peanut allergy can be treated with a safe and effective approach, allowing them to tolerate larger doses of peanut butter. The treatment involves gradually increasing doses over 18 months, resulting in sustained unresponsiveness to peanuts fo...

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNEJM Evidence·TypeExperimental study·DateFeb 10, 2025

Air pollution linked to having a peanut allergy during childhood

A new study found that exposure to higher levels of air pollution as a baby is associated with increased odds of developing a peanut allergy and having it persist throughout childhood. Policies aimed at tackling poor air quality could potentially reduce the development and persistence of peanut allergies, according to researchers.

SourceMurdoch Childrens Research Institute·JournalJournal of Allergy and Clinical Immunology: In Practice·TypeObservational study·DateOct 22, 2024

New test improves diagnosis of allergies

A new test mimics allergic reactions in a test tube, showing higher diagnostic accuracy than standard tests for peanut allergy and potentially other allergies. The Hoxb8 Mast Cell Activation Test (Hoxb8 MAT) has been shown to have an exceptionally high diagnostic accuracy of 95% and leads to fewer false negative results.

SourceUniversity of Bern·JournalAllergy·TypeRandomized controlled/clinical trial·DateOct 15, 2024

Microrespirometric validation of a two-stage process for polyhydroxyalkanoates production from peanut oil and propionate with cupriavidus necator

This study validates a two-stage process for producing polyhydroxyalkanoates (PHA) using peanut oil and propionate with Cupriavidus necator. The findings show that peanut oil is the most beneficial carbon source, leading to increased biomass and PHA production.

SourceBentham Science Publishers·JournalThe Open Chemical Engineering Journal·DateMay 29, 2024

Antibody reduces allergic reactions to multiple foods in NIH trial

A monoclonal antibody, omalizumab, increased the tolerance threshold for multiple food allergens, allowing children to consume larger amounts without a reaction. The treatment showed significant benefits in reducing allergic reactions, particularly for peanut and egg, with potential protection against accidental exposure.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalNew England Journal of Medicine·DateFeb 25, 2024

Allergic reactions prevented with decorated nanoparticles

Scientists have created a new therapy using nanoparticles to target specific immune cells responsible for allergic responses. The approach, which combines an allergen with antibodies that selectively inhibit mast cells, has shown promising results in a mouse study, preventing allergic reactions without causing side effects.

SourceNorthwestern University·JournalNature Nanotechnology·TypeExperimental study·DateJan 16, 2024

For toddlers allergic to peanuts, a tiny bit of protein therapy under the tongue could be the best approach

A clinical trial found that Peanut SLIT is safe and effective in children aged 1-4 years, with over 80% tolerating peanuts without allergic symptoms after treatment. Remission of peanut allergy was also possible, with 63% maintaining protection three months after stopping the treatment.

SourceUniversity of North Carolina Health Care·JournalJournal of Allergy and Clinical Immunology·TypeRandomized controlled/clinical trial·DateOct 13, 2023

Mummified poop reveals pre-Columbian cultures of the Caribbean consumed a diversity of plants, with peanuts, papaya, maize, and even cotton and tobacco detected

A study published in PLOS ONE reveals that pre-Columbian Caribbean cultures consumed a wide variety of plants, including sweet potato, chili peppers, and domesticated tomatoes. The analysis also detected tobacco and cotton, challenging the traditional staple food narrative.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateOct 11, 2023

Allergies in Europe: regional differences in sensitization profiles identified in children for the first time

A comprehensive European allergy atlas has been compiled, revealing regional and climate-related differences in sensitisation to allergens. The study found varying sensitisation patterns across Europe, with certain regions having lower sensitivity to house dust mites and higher sensitivity to peanut and fruit allergens.

SourceMedical University of Vienna·JournalAllergy·DateMar 9, 2023

Researchers discover potential way to prevent life-threatening allergic reactions for those with peanut allergies

Scientists at Indiana University School of Medicine have developed a new treatment that blocks anaphylaxis caused by peanut allergies, potentially saving lives. The covalent heterobivalent inhibitor (cHBI) was tested in animal models and showed promise in preventing allergic reactions for over two weeks.

SourceIndiana University School of Medicine·JournalScience Translational Medicine·DateFeb 9, 2023

Can boiled peanuts help cure peanut allergies?

A phase 2 clinical trial using boiled peanuts followed by roasted peanuts showed promising results in desensitizing 80% of children with peanut allergies. Treatment-related adverse events were reported in 61% participants.

SourceWiley·JournalClinical & Experimental Allergy·DateJan 11, 2023

Clinical trial shows boiled peanuts could help overcome child peanut allergy

A clinical trial found that boiling peanuts for up to 12 hours can desensitize children with peanut allergies. The therapy involved sequential doses of boiled and roasted peanuts, achieving high success rates in participants. While promising, the study's findings require confirmation in larger trials.

SourceFlinders University·JournalClinical & Experimental Allergy·TypeRandomized controlled/clinical trial·DateJan 11, 2023

Research shows care from an allergist results in lower health care costs for children with peanut allergy

Researchers used big datasets to show that annual health care costs were significantly higher among children without allergist care for peanut allergy compared to those who received care. Care from an allergist resulted in lower total health care costs, saving $1,923 per child.

SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of Allergy and Clinical Immunology·TypeData/statistical analysis·DateOct 24, 2022

Oil-based systems show promise for eradicating salmonella on food production machinery

A new study published in Applied and Environmental Microbiology suggests that oil formulations with food-grade organic acids can kill dried Salmonella on stainless steel surfaces. This approach has the potential to replace water-based cleaning methods, which promote microbial growth and are often challenging to use.

SourceAmerican Society for Microbiology·JournalApplied and Environmental Microbiology·TypeExperimental study·DateAug 8, 2022

NTU Singapore and ETH Zurich scientists decontaminate heavy metal water using protein from plant waste

Scientists have created a membrane made from a waste by-product of vegetable oil manufacturing that can filter out heavy metals from contaminated water. The membrane uses proteins derived from peanut or sunflower oil production to attract and trap heavy metal ions, purifying water to international drinking standards.

SourceNanyang Technological University·JournalChemical Engineering Journal·TypeExperimental study·DateJun 23, 2022

Peanut allergy treatment safest when started for infants under 12 months

A new study published in the Journal of Allergy and Clinical Immunology: In Practice found that infants under 12 months who undergo oral immunotherapy have a better safety profile compared to older preschoolers. The treatment, which involves gradually increasing exposure to peanut flour, is highly effective and safe for this age group.

SourceUniversity of British Columbia·JournalJournal of Allergy and Clinical Immunology: In Practice·TypeObservational study·DateJun 16, 2022

Caesarean births not linked to increased risk of food allergy during infancy

A recent study published by the Murdoch Children's Research Institute found no significant association between caesarean birth and the development of food allergies in infants. The research involved over 2,000 infants and suggested that babies born via caesarean delivery are not at a higher risk of developing food allergies.

SourceMurdoch Childrens Research Institute·JournalJournal of Allergy and Clinical Immunology: In Practice·TypeObservational study·DateMay 18, 2022

Serious allergic reactions to food among children stabilize since guideline changes

A new study found that serious allergic reactions to food among children have flattened since changes to Australian infant feeding guidelines. The research showed a slowing rate of increase in hospital admissions for food anaphylaxis among young children and teenagers, but overall rates remain high. Experts emphasize the need for effec...

SourceMurdoch Childrens Research Institute·JournalJournal of Allergy and Clinical Immunology·DateFeb 23, 2022

Researchers discover two treatments that induce peanut allergy remission in children

Two new treatments have been found to induce peanut allergy remission in children, with about half achieving remission and experiencing significant improvements in quality of life. The combination treatment and oral immunotherapy alone were both highly effective, providing substantial benefits for children's health and well-being.

SourceMurdoch Childrens Research Institute·JournalThe Lancet Child & Adolescent Health·TypeRandomized controlled/clinical trial·DateFeb 4, 2022

THE LANCET: Initiating peanut oral immunotherapy in peanut-allergic children under age four may be more effective, first long term study suggests

A randomised controlled trial found that most young children treated with peanut immunotherapy achieved desensitisation after two and a half years of treatment, while one in five remained in remission. Younger children under one year old were more likely to achieve remission, suggesting early interventions may provide better outcomes.

SourceThe Lancet·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateJan 20, 2022

Peanut studies reveal surprising truths about RNA and open the door to better understanding epigenetic mechanisms in plants

Scientists have discovered a new layer of regulation in plant-microbe interactions using peanut studies. An antisense long-noncoding RNA, DONE40, was found to bind to a protein involved in epigenetic control, suggesting a conserved function across plants and animals.

SourceAmerican Phytopathological Society·JournalMolecular Plant-Microbe Interactions·TypeExperimental study·DateJan 13, 2022

Four years after release of guidelines, parents still not informed about early peanut introduction

A new study reveals that only 40% of parents received a recommendation to introduce peanut products by 11 months of age, despite the 2017 guidelines. The survey also found that most infants are at moderate- or low-risk for developing peanut allergies and can safely have peanut-containing foods introduced.

SourceAmerican College of Allergy, Asthma, and Immunology·JournalAnnals of Allergy Asthma & Immunology·TypeSurvey·DateNov 5, 2021

Peanut consumption: Potential benefits in young and healthy people

A study published in Clinical Nutrition Journal found that daily peanut consumption improved cognitive function and stress response in young and healthy individuals. The researchers discovered that bioactive compounds such as resveratrol and p-coumaric acid, as well as short-chain fatty acids, contributed to the health effects.

SourceUniversity of Barcelona·JournalClinical Nutrition·TypeRandomized controlled/clinical trial·DateOct 7, 2021