Articles tagged with Radiation
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A shortened radiotherapy schedule has been shown to have similar efficacy as a conventional course in treating low-risk prostate cancer. The study found that patients treated with the shorter schedule experienced no significant decrease in cancer control compared to those treated with the longer conventional schedule.
A study published by the University of Texas M. D. Anderson Cancer Center found that intensity modulated radiation therapy (IMRT) reduced severe pneumonitis and improved chemotherapy tolerance in patients with locally advanced non-small cell lung cancer compared to conventional radiation therapy.
A study of 47,000 patients found that nearly a third received more than 25 radiation treatments, despite guidelines recommending no more than 15. Privately insured patients were 40% more likely to be overtreated, highlighting the need for education and financial transparency.
The American Society for Radiation Oncology (ASTRO) has awarded a total of $33,500 to 41 researchers for their outstanding contributions to the field of radiation oncology. The awards recognize top-rated abstracts presented at the 2015 Annual Meeting, with recipients receiving cash honors and complimentary registration.
The American Society for Radiation Oncology has selected seven leading physician-researchers to receive a total of $675,000 in awards and grants to advance radiation oncology research. The recipients will support studies in radiation and cancer biology, as well as outcomes/health services research within radiation oncology.
Physicists suggest detecting dark matter through radiation signals created by particle collisions, increasing chances of detection in underground detectors and specific areas in space. The current satellite-based experiments may have been searching for the wrong signals.
Women with early-stage breast cancer who receive a shorter course of whole breast radiation therapy experience less toxicity and improved quality of life compared to those who undergo a longer course of treatment. The study suggests that hypofractionated treatment should be considered as a starting point for discussion between patients...
Researchers at the University of North Carolina have discovered a rare type of stem cell that is immune to radiation damage due to high levels of Sox9. This finding could lead to new ways to protect the gastrointestinal system of cancer patients before treatment, allowing for more aggressive treatments to be used.
A new study found that increased radiation dose offers no survival benefit for patients with low-risk prostate cancer. In contrast, men with medium- and high-risk cancers saw improved survival rates with higher doses.
The American Society for Radiation Oncology (ASTRO) has launched a new open-access journal, Advances in Radiation Oncology, with Founding Editor Robert C. Miller, M.D. The journal will publish original research on novel retrospectives and hypothesis-generating series, with a focus on practice transformation.
Researchers at Tufts University have observed individual atoms of iodine-125 decay and transform into tellurium-125 using a scanning tunneling microscope. The gold-bonded isotopes emit six times more low-energy electrons, which could destroy tumor DNA without affecting healthy tissue.
Researchers found that stereotactic body radiation therapy (SBRT) is safe and as effective as standard radiation treatment for certain patients with locally advanced pancreatic cancer. SBRT delivers high doses of radiation in a short period, resulting in reduced pain and improved quality of life. The treatment also allowed some patient...
A novel blood test can rapidly predict the severity of radiation injury, enabling timely medical intervention and improving overall survival. The test uses microRNA biomarkers to determine the functional impact of radiation on bone marrow and other organs.
The American Society for Radiation Oncology (ASTRO) has issued a new guideline on definitive and adjuvant radiotherapy in locally advanced non-small cell lung cancer, citing 35 years of data to guide current treatment and future research. The guideline recommends RT as the ideal treatment for patients with locally advanced NSCLC.
Researchers have successfully detected cyclotron radiation from single electrons, a phenomenon predicted in 1904, and developed a new method to measure the energy of electrons. This technique has the potential to determine the mass of neutrinos, which are essential for understanding the universe's large-scale structure.
A population-based study found brachytherapy with external beam radiation improved overall survival by 13% for women with inoperable stage 1 endometrial cancer. Brachytherapy was also associated with lower deaths from endometrial cancer after three years.
A study of combined intracavitary and interstitial brachytherapy for cervical cancer treatment found that the technique delivers higher radiation doses to tumors without increasing treatment-related problems. The method successfully targets the tumor while avoiding other organs, leading to a better chance of cure.
A protocol developed by radiologists significantly reduced CT misadministration at the Santa Clara Valley Medical Center from 18 instances to zero in just 10 months. The best practices protocol included assessment levels such as reverification checklists and individual accountability.
Research finds that thinner slice thicknesses of 0.5-1 mm can accurately measure coronary artery calcium with isotropic data acquisition at the same radiation dose. This method reduces inaccuracies caused by partial volume averaging errors found in standard 3 mm slices.
Recent studies show that bird populations are declining in Fukushima, with dramatic decreases in species and numbers, despite a decrease in background radiation levels. The research suggests that exposure to radiation is causing toxic effects, leading to impaired DNA repair capabilities in migratory birds.
Researchers have developed a method to increase radiation's effectiveness in killing cancer cells by using gold nanoparticles tethered to acid-seeking compounds. The approach, published in PNAS, shows promising results and may improve radiation treatment for cancer patients.
New research shows that black holes do not erase information, but rather preserve it through the interactions of particles emitted by the black hole. This discovery challenges the long-standing 'information loss paradox' in physics.
A new engineered protein-based medicine has been shown to overcome radiation resistance in leukemia by selectively binding to leukemia cells and amplifying the potency of radiation therapy. In mouse models, this precision medicine improved survival rates in aggressive human leukemia with minimal side effects.
Researchers found delayed radiation therapy offers no protective benefit and may increase risk of complications, contradicting the long-held view. Adjuvant therapy soon after prostate removal is effective in curing patients with low-grade disease.
Researchers found that combining radiation with ipilimumab shrank tumors in some patients. The team also identified the PD-L1 pathway as a mechanism of resistance, suggesting an ideal third treatment to improve response and immunity.
Scientists at MD Anderson Cancer Center have discovered a key DNA pathway that allows certain brain cancers to resist standard treatments. The study found that activation of this pathway leads to enhanced survival of tumor cells and increased DNA repair, contributing to treatment resistance.
A study published in the Journal of the American College of Cardiology found that frequent radiation exposure and heavy protective gear are associated with increased musculoskeletal pain among technicians and nurses. Researchers recommend improving ergonomic evaluations and rotation to mitigate these effects.
A 2013 survey of radiation oncologists found that peer review is a common practice in medicine, but there is wide variation in its performance. Seventy-eight percent of respondents reported being involved in peer review, and 74% expressed interest in formal guidelines to improve the process.
Women undergoing left-side breast cancer radiation therapy can reduce heart exposure by holding their breath, resulting in a 90% disease-free survival rate and a median reduction of 62% in radiation dose. The breath-hold technique also shows a lower risk of ischemic heart disease after 8 years.
A University of Colorado Cancer Center study reveals that reprogramming damaged stem cells can prevent cancer after full-body radiation. The research suggests that genetic inhibition of the C/EBPA gene allows healthy stem cells to dominate the blood cell production system, reducing the risk of leukemia.
A study found that radiologist recommendations for chest computed tomography (CT) after abnormal chest X-rays have a high clinical yield, with 41.4% of recommended exams detecting cancer or other abnormalities requiring treatment.
A study published in JAMA found that many breast cancer surgery patients do not receive shorter radiation treatment, despite guidelines recommending it for selected patients. Hypofractionated WBI has been shown to be equally effective as conventional WBI but with lower health care costs and reduced treatment burden.
A new study reveals that two-thirds of women treated for early-stage breast cancer in the US receive longer radiation therapy than necessary, despite multiple randomized trials and professional society guidelines showing that hypofractionated radiation is clinically effective and less costly.
A new analysis found that nearly two-thirds of elderly women with early stage breast cancer continue to receive radiation therapy despite clinical trial data suggesting it may not be effective. The findings highlight the challenges in implementing clinical trial results into practice patterns, particularly due to concerns about long-te...
Researchers developed a device to display average pressure during compression, reducing pain and variability associated with current force-based protocol. The study found that standardizing pressure, not force, leads to more comfortable mammography without sacrificing image quality.
Researchers at Northwestern University developed a compact terahertz radiation source that operates at room temperature, offering improved security detection capabilities. The device has a wide frequency coverage and can detect explosives, chemical agents, and biological substances from safe distances.
A team of researchers reveals that dendritic cells activate killer T cells through a protein named STING, which links DNA damage to interferon-β production. This suggests novel strategies for boosting radiotherapy effectiveness and combining it with immune system therapies.
The STING pathway plays a crucial role in detecting tumor cells and promoting an aggressive anti-tumor response. Activating the pathway triggers production of chemical signals that help the immune system identify tumor cells and generate killer T cells.
African Americans and Hispanics are less likely to receive effective radiation therapy for early-stage lung cancer, according to a study. The study highlights significant disparities in treatment options based on hospital type and insurance status.
Researchers developed an anti-cancer drug that protects normal cells from radiation damage while sparing cancer cells. The compound, RTA 408, increases the effectiveness of radiation therapy in prostate cancer models and has potential applications for treating accidental radiation exposure.
Researchers found that pretreatment interstitial lung disease significantly increases the risk of developing symptomatic and severe radiation pneumonitis in stage I non-small cell lung cancer patients treated with stereotactic body radiation therapy. The study's results suggest that clinicians should be cautious when considering SBRT f...
A new study found that chest radiation in childhood cancer patients increases their risk of developing breast cancer later in life. Nearly 20% of female survivors who received chest radiation developed breast cancer by age 40 compared to 0.3% of those who did not receive radiation.
A simple test called transcutaneous oximetry may predict which patients are most likely to experience wound-healing complications after surgery. Patients with lower oxygen levels before surgery were more likely to develop complications, highlighting the potential tool as a means of taking extra precautions.
A new biomarker, CLIP2, has been discovered that distinguishes between radiation-induced and sporadic thyroid carcinomas. The marker increases in both genetic activity and protein expression after radiation exposure.
The Edge Radiosurgery Suite provides sub-millimeter accuracy with extreme precision in targeting cancer tumors. The study demonstrates its high accuracy, outperforming robot- or frame-based radiosurgery systems, making it a highly effective treatment option for patients.
A phase I/II trial of hypofractionated radiation therapy found that prostate cancer patients reported similar quality of life, bladder and bowel function before and after treatment. The study's results also indicated that different regimens of hypofractionated RT produced similar outcomes in terms of patient-reported quality of life.
Charlie Ma, Ph.D., a Professor and Director of Medical Physics at Fox Chase Cancer Center, has been selected as an ASTRO Fellow. He is recognized for his contributions to the field of radiation oncology, including research, education, and patient care.
Researchers found that radiation oncologists are using fewer or less-aggressive radiation procedures on elderly women with early-stage breast cancer. The study confirms that radiation oncologists are successfully balancing patients' needs with the cost of providing healthcare.
A study found that combining chemotherapy and stereotactic ablative radiation (SABR) may be an effective treatment option for patients with locally advanced pancreatic cancer. After undergoing this treatment, nearly 90% of patients were able to undergo surgery, resulting in a high success rate.
Researchers analyzed data from over 17,000 surveys to track changes in urinary and sexual symptoms following various prostate cancer treatments. The study found that certain treatments, such as surgery and low-dose rate brachytherapy (LDR), may cause temporary increases in symptoms, while others, like intensity modulated radiation ther...
A study of 91 prostate cancer patients found that vessel-sparing radiation therapy preserves sexual function without compromising cure rates. Patients who received combination EBRT and brachytherapy reported improved sexual function at five years post-treatment.
A study in mice implanted with breast and melanoma cancers found that combining radiation therapy with a checkpoint inhibitor increases antitumor responses from the immune system. The combination also enhances memory T-cells, which retain memory of the tumor and can attack it long after treatment.
A study of over 41,000 patients with stage I and II Hodgkin's Disease found that those receiving consolidated radiation therapy had a higher 10-year survival rate of 84 percent compared to 76 percent for non-RT recipients. The data also showed a decrease in RT utilization, highlighting ongoing disparities in treatment.
Researchers from Montefiore and Einstein present findings on radiation therapy duration, dosing recommendations, and predictive indicators for clinical outcomes in locally-advanced cancers. The studies focus on improving personalized cancer care and overcoming treatment barriers.
A new breast cancer radiation trial offers once-weekly regimens with no adverse effects, resulting in better completion rates and lowered costs. The study found that this approach allows for more convenience and choice for patients, improving their ability to complete treatment, while reducing costs by up to 50-60%.
A study found a substantial increase in double mastectomy use among California women with early-stage breast cancer between 1998 and 2011. Despite the procedure's lack of association with lower mortality rates compared to breast-conserving surgery plus radiation, its higher risk of death was noted.
Manchester scientists have developed a method to personalize and increase radiotherapy doses for lung cancer patients, potentially improving local control and survival rates. The technique uses intensity modulated radiotherapy (IMRT) to minimize harm to healthy tissue.
The American Society for Radiation Oncology (ASTRO) has awarded a total of $35,500 in individual grants to 43 researchers presenting at the 2014 Annual Meeting. The awards recognize top radiation oncology research from around the world and provide insight into significant advances in technology and biology.
Seven physicians receive funding to advance radiation oncology research, including studies on cancer biology, physics, and treatment outcomes. Recipients will focus on improving radiation therapy and enhancing patient care.
Researchers at Cedars-Sinai Medical Center are developing a combined investigational treatment for locally advanced pancreatic cancer, combining radiation with chemotherapy and a PARP inhibitor. The study aims to identify patient biomarkers that can provide clues into individual treatment response and improve survival rates.