Articles tagged with Research On Children
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A CHLA research team found that socio-economic factors like family support, employment status, patient age, race, and language spoken can impact clinical outcomes. Children with limited social support systems and working caregivers have worse outcomes.
A comprehensive report on pediatric long COVID symptoms has been published, revealing clues to risk factors and common symptoms such as fatigue, headaches, and musculoskeletal pain. The study found that older age, more severe initial infection, and underlying medical conditions are associated with an increased risk of long COVID.
Children's Hospital Colorado is one of nine core sites nationally in the Pediatric Heart Network, a collective working to improve outcomes and quality of life for children with heart disease. The hospital's Heart Institute will conduct multisite research projects over the next seven years.
Johns Hopkins researchers have made progress toward developing a blood test to identify disease-associated changes in the brain linked to postpartum depression and other psychiatric disorders. They identified 26 placental mRNAs present in maternal blood only during pregnancy, which reflected changes occurring inside the tissues.
The American Heart Association and The Children's Heart Foundation have pledged over $10 million in funding to research congenital heart defects. Researchers will advance their work to improve diagnosis, treatment, and prevention of CHDs, giving more children a chance to grow into healthy adults.
Researchers conducted in-depth interviews with 47 parents experiencing homelessness to understand accessibility challenges of social-emotional health services for their children. Key findings include the importance of acknowledging parental strengths and positive interactions with support people in promoting child development.
A large study of nearly 200,000 newborns in Sweden and Norway found that COVID-19 vaccination during pregnancy was not associated with any increased risks in newborn infants. In fact, babies born to vaccinated mothers had lower mortality rates and fewer serious complications.
A Johns Hopkins Children's Center study found that cost-driven housing moves, such as evictions and foreclosures, disrupt access to WIC, SNAP, and Medicaid for 21% of children. The study highlights the importance of maintaining safety net benefits for families during times of financial strain.
Researchers investigate biomarkers from genome, transcriptome, proteins, and metabolites to help tackle the high mortality rate of pediatric sepsis. The review highlights potential biomarkers, including genomics, transcriptomics, proteomics, and metabolomics.
Christi Bergin's research focuses on improving prosocial behavior in classrooms and communities, leading to better student engagement, academic achievement, and relationships. Her approach aims to reduce teacher stress and burnout by promoting empathy and kindness among students.
A new study suggests that instrumental lies and white lies told by parents can encourage children to lie, with the effect seen only when children know they have been lied to. This finding highlights a need to understand the relation between parental lying and children's outcomes.
A Brazilian study found that prior zika infection significantly increases the risk of developing severe dengue and being hospitalized. The study analyzed samples from over 1,000 laboratory-confirmed dengue patients and identified a higher viral load and inflammatory cytokine levels in those with prior zika infections.
A study of over 580 children found that childhood trauma disrupts neural networks involved in self-focus and problem-solving. The research suggests that trauma therapies should address not only thoughts but also the impact on the body, sense of self, emotional processing, and relationships.
Researchers discovered a new role for Mfsd7c in exporting excessive choline from the brain. The study suggests that targeting this protein could lead to therapeutic interventions for Alzheimer's disease and other neurological disorders.
A team of researchers found that diffuse anaplasia (DA) subtype of Wilms tumor grows despite high DNA damage and TP53 mutation, leading to resistance to chemotherapy. The study suggests that DA histology emerges through accumulating DNA damage and CNAs, creating selection pressure for TP53 mutations.
A study by Florida Atlantic University found that immigrant bilingual Latina mothers retain cultural practices in play conversations with their children, particularly when speaking in their heritage language. The mothers' behavior changes when switching languages, extending to language use with young children.
A combination of two cancer drugs has shown promise in treating malignant peripheral nerve sheath tumors (MPNSTs), a type of cancer that is notoriously hard to treat. The study found that the combination therapy of SHP2 inhibitors and CDK4/6 inhibitors suppressed tumor growth and triggered cell death in mouse models.
A new study found that emerging adults appreciate their parents' unsolicited advice if they are supportive of their autonomy. Parents can foster this by providing clear guidelines and participating in activities interesting to their teens. Conversely, dismissive postures like 'Because I said so' can cause teens to build walls around un...
A rare disorder causing extra fingers and toes has been identified through research led by the University of Leeds, linked to a genetic mutation in the MAX gene. The study found a molecule that could potentially treat neurological symptoms associated with the condition.
Liquid biopsies have the potential to monitor therapy success and predict tumor recurrence in high-risk neuroblastoma patients. The MONALISA project aims to establish liquid biopsies as a standard procedure for monitoring relapsed neuroblastoma, offering hope for improved personalized medicine.
A University of Houston optometry researcher has warned against using low-level red light therapy for myopia in children due to potential retinal damage. The therapy, which involves prolonged exposure to a red light-emitting instrument, can put the retina at risk of photochemical and thermal damage.
A new study confirms that the predominant outcome of non-fatal pediatric drowning is locked-in syndrome. Researchers found that 60% of children who survived drowning events were classified as locked in, with cognitive and sensory networks preserved in their brains.
A single dose of the typhoid conjugate vaccine provided lasting protection against typhoid fever in over 28,000 healthy children in Malawi. The vaccine efficacy remained strong over four years, with a 78.3% efficacy rate and one case prevented for every 163 children vaccinated.
The COVID-19 pandemic caused a 45% increase in childhood obesity among 4-5-year-olds in England, persisting into 2022. The study found that this group will incur an additional £800 million in healthcare costs over their lifetimes.
Researchers develop technology that alleviates retinal pathologies by targeting mitochondrial chaperone TRAP1, which is implicated in the breakdown of blood-retinal barrier and pathological neovascularization. This treatment approach holds great promise for revolutionizing the treatment landscape for ischemic retinopathy.
A new study finds that infants born full-term to mothers infected with COVID-19 during pregnancy are three times more likely to develop respiratory distress compared to uninfected infants. Vaccination prior to infection was found to be protective, reducing the risk by half.
Research reveals that stable and supportive caregiving during childhood can protect cardiovascular health later in life, contrary to previous findings on childhood adversity. The study analyzed over 2,000 participants and found that each additional unit score of caregiver warmth was associated with 11.7% higher odds of cardiovascular h...
Research finds that stable caregiver relationships in childhood may increase optimal heart health, while adversity and abuse can lead to poor cardiovascular health. Lower income as an adult may also introduce additional adversity, making the relationship between caregiver-child adversity difficult to see.
Researchers found that access to community perinatal mental health teams significantly improved the risk of acute relapse, but also associated with increased stillbirth and neonatal death rates. Women with severe mental illnesses had a lower risk of relapse after birth in regions with CPMHTs.
A new study found that propranolol, a medication for high blood pressure, can lower anxiety levels in individuals with autism spectrum disorder. The study involved 69 patients and showed significantly reduced anxiety levels compared to a placebo group.
This study explores how better communication with care teams can improve the birthing experience for Black people. Researchers found that addressing urgent procedures and fostering a welcoming environment to share birth experiences mitigated negative consequences of preterm births.
A recent study of 2,261 infants found no significant adverse effects on neurodevelopment after in utero exposure to COVID-19 vaccination. The research suggests that maternal COVID-19 vaccination is safe for infant development up to 18 months.
A new MIT study found that children from lower socioeconomic backgrounds show less sensitivity to rewarding experiences, which can impact motivation and attention. The research suggests that the brain adapts to its environment by dampening its response to rewards, making it less responsive in low SES environments.
A new set of international criteria has been established to diagnose pediatric sepsis and septic shock in children, aiming to improve clinical care and research globally. The Phoenix Sepsis Score of at least 2 can identify potentially life-threatening organ dysfunction in infected children under 18 years old.
A new epidemiological study reveals that bacterial meningitis can cause significant and lasting neurological disabilities in children. The infection can be cured with antibiotics, but it often leads to permanent impairment. Researchers analyzed data from over 3,500 people who contracted bacterial meningitis as children and found a high...
A new study found that young adults who reported higher stress as adolescents were more likely to have high blood pressure, obesity, and other cardiometabolic risk factors. This highlights the importance of stress management from an early age to prevent these health issues.
Researchers found that bone marrow mononuclear cell infusion in children within 48 hours of severe traumatic brain injury reduced intensive care needs and preserved white matter. The treatment also enhanced connectivity in the corpus callosum, a midline structure in the brain.
Research finds that changes in mouse sperm microRNAs caused by aging may affect offspring growth and development, increasing the risk of neurodevelopmental disorders like autism. The study's findings add to growing literature on paternal aging and its impact on offspring health.
A new study published in Nature Communications found that AI-driven eye exams can close care gaps among racial and ethnic minority youth with diabetes, populations with historically higher rates of diabetic retinopathy. The technology uses cameras to take pictures of the back of the eye without dilation and provides immediate results.
Researchers from Binghamton University are unraveling the workings of Group B Strep (GBS) infections, which could someday lead to a vaccine. They have identified a novel protein that could serve as a vaccine candidate to fight this bacterium, impacting women's reproductive health and neonatal outcomes.
A study redevelops a framework for teaching artificial intelligence and robotics to preschool children, providing five big ideas that can be grasped by young kids. The framework aims to prepare children to understand and use AI tools effectively, promoting healthy and responsible learning in the rapidly developing digital society.
Researchers studied cellular functions in medulloblastoma to understand its genetic causes and develop targeted therapies. The study identified essential microproteins that play a crucial role in the survival of cancer cells.
A new study found that fentanyl-laced prescription pills are driving a surge in overdose deaths among high school age adolescents in the US. The death rate for this group has increased to 5.2 per 100,000, with Arizona and Colorado experiencing rates double the national average.
Researchers found that infants with enlarged perivascular spaces have a 2.2 times greater chance of developing autism compared to those with the same genetic risk. The study also indicates that these infants are more likely to experience sleep problems seven to ten years after diagnosis.
Several key public health occupations, including disease intervention specialist and program manager, do not have valid SOC matches, creating challenges in researching the workforce. The study's findings highlight the need for standardization to characterize the public health workforce linked to SOC codes.
Researchers found that less than two percent of patients in Medicaid and commercially insured plans received Z-codes to document Social Determinants of Health. The study highlights the need for improved tracking and documentation of SDOH in healthcare settings, with recommendations for policy changes and provider education.
Researchers have discovered that immune cells play a crucial role in directing the growth of human lung tissue during development, revolutionizing our understanding of early lung development. The findings also suggest that early immune disturbances could manifest as pediatric lung disease.
A recent US study found that parents overestimate the value of free play in children's learning, while undervaluing guided play. Guided play is more effective for teaching skills like mathematics, language, and STEM subjects. By educating parents on this approach, they can create engaging 'learning' moments during everyday activities.
A new study found that increased sedentary time in childhood can raise cholesterol levels by two thirds as an adult, leading to heart problems. However, light physical activity was shown to be up to five times more effective than moderate-to-vigorous physical activity at promoting healthy hearts and lowering inflammation.
Researchers at UCL Queen Square Institute of Neurology have developed a new gene therapy that significantly reduces seizures in mice with focal cortical dysplasia. The treatment, which involves the overexpression of a potassium channel, has shown an average reduction of 87% in seizures without affecting the mouse's memory or behavior.
A national study using telehealth assessments aims to identify infants with early behavioral differences that may indicate autism or developmental delays. The study will provide valuable insights into predicting these developmental skills and offer improved feedback and support for families.
A new longitudinal study has found a strong link between body dissatisfaction and depression in children, with high BMI at age seven increasing depressive symptoms by age 14. Body dissatisfaction was the major contributor to this association, explaining 43% of the link.
A global study of 1,001 children across 12 countries found that adult talk is the key predictor of language development in infants and toddlers. No effects were found related to socioeconomics or multilingualism.
Two studies found moderate to high risk scores for cancers and non-cancer health effects associated with lead, arsenic, and cadmium exposure. Exposure to these heavy metals through contaminated food is linked to increased risks of various types of cancer, including lung, bladder, skin, and prostate cancers.
Researchers found that AI systems are skilled at solving problems by finding novel uses for everyday objects, like humans. However, they lack the ability to innovate on these ideas and often rely on statistical pattern prediction.
Researchers have developed an AI-powered system to diagnose autism spectrum disorder (ASD) in children using a single flash of light to the eye. The system uses electroretinography (ERG) to identify specific features that classify ASD, providing a faster and more accurate method for diagnosis than existing tests.
Research found elevated risks between intimate partner violence and childhood sexual abuse and various health conditions. Intimate partner violence was associated with increased risk of major depressive disorders, maternal abortion, and alcohol misuse, while childhood sexual abuse linked to increased risk of self-harm and alcohol use.
Researchers used NIRS to track oxygenated hemoglobin levels in infant brains responding to gentle touch. They found similar response times across age groups, but varying signal amplitudes that may be linked to changes in blood flow and erythropoietin production.
Gene therapy treatments can prompt an adverse immune reaction when the body mistakenly perceives the treatment as a viral threat. Researchers have identified a critical pathway in the liver that triggers this response, but also found a way to block it, paving the way for safer and more precise gene therapy options.
A Harvard Pilgrim Health Care Institute study found a strong link between higher prenatal PFAS exposure and increased rates of obesity and body fat in adolescent offspring. Higher levels of certain PFAS were associated with a 13-59% increase in the risk of obesity, highlighting the long-term consequences of PFAS for developmental health.