Articles tagged with Medical Research Facilities
Researchers identified lamin A and lamin B receptor proteins as essential for maintaining gene position in the nucleus. Their absence causes genes to malfunction, leading to heart failure, vascular disease, and muscle wasting. This discovery may lead to new treatments for these diseases.
Research published in the Journal of Dental Research shows that beta-catenin is crucial for odontoblast cell differentiation and root development. Tissue-specific inactivation of beta-catenin in developing odontoblasts resulted in molars lacking roots and thin incisors.
Researchers discover that belly and thigh fat differ significantly in gene expression, with unique homeobox genes influencing fat cell behavior. This finding may lead to targeted treatments for obesity, shifting focus from belly fat to hip and thigh fat.
The university will extend its world-class structural biology facilities by developing a state-of-the-art instrument for the new synchrotron user facility. The grant aims to provide detailed structural information that can benefit the entire scientific community.
Duc Dong, Ph.D., receives NIH New Innovator Award to explore genetic reprogramming as a means to grow replacement organs. The technology aims to induce new tissue development in zebrafish, allowing for rapid screening of genes and chemicals important for efficient genetic reprogramming.
A recent study published in the Journal of Dental Research estimates that approximately 47.2% of US adults have periodontitis, with higher rates among males, Mexican Americans, and those with lower education levels. The study also found significant disparities in periodontal disease prevalence across different age groups.
Researchers at Sanford-Burnham Medical Research Institute discovered that BACE1 disrupts cellular processes required for PKA function, leading to impaired learning and memory. This finding suggests that targeting BACE1 expression in the brain could be a potential therapy for Alzheimer's disease and age-related memory loss.
Researchers have identified a new function for APJ protein in sensing mechanical changes that can lead to heart failure. Without this protein, the heart is less likely to sense danger and undergo hypertrophic pathways leading to heart failure.
Researchers examine past five years of underwater deliveries by HealthNet midwives to determine maternal and baby health indicators, aiming to improve reproductive health care. The study's findings will inform national policy and contribute to the field's adoption of health information technology.
Researchers have reevaluated the Yellowstone volcano's history, finding that its biggest eruption was actually two separate events 6,000 years apart. This new understanding may lead to a revised likelihood of another large eruption in the future.
Researchers from Notre Dame's Eck Institute for Global Health have developed a novel method using a gene chip to identify malaria drug resistance. This technology enables real-time response and modification of treatment strategies to combat emerging resistance.
Boston Medical Center physician Jeffrey Samet, MD, received a $1.4 million NIDA grant to develop the Research in Addiction Medicine Scholars (RAMS) Program, which aims to create formal addiction medicine training programs with strong research components.
Dr. Richard H. Carmona receives AADR's Honorary Membership for his dedication to promoting oral health as U.S. Surgeon General and beyond. The American Association for Dental Research recognizes Dr. Carmona's significant contributions to dental research.
Researchers at University of Leicester found a significant link between the Y chromosome and an increased risk of coronary artery disease in men. The study analyzed DNA from over 3,000 men and found that 90% of British Y chromosomes belong to two major groups that increase the risk by 50%.
A symposium on tissue injury and pulp regeneration has published proceedings that highlight the potential of dental pulp engineering for regenerating functional dentin. Researchers present data on stem cells, scaffolds, and differentiation factors, demonstrating proof of principle for pulp/dentin regeneration.
The Broad Institute of MIT and Harvard has received a $50 million gift from the Stanley Medical Research Institute to extend funding for its Stanley Center for Psychiatric Research. Researchers will continue to unravel the genetic mysteries of psychiatric illnesses, aiming to develop new treatments for patients.
Researchers are developing a new antidote to regenerate an enzyme that ages after exposure to deadly chemical warfare agents. Dr. Christopher Hadad is using supercomputers to test reagents for this treatment, which could provide complete recovery from severe muscle spasms and death.
Researchers compared two pulp extraction techniques on dental pulp stem cells (DPSC) quality and quantity. The study found that the second technique resulted in higher stem cell integrity, growth rate, and quality, while also improving quantity.
This study evaluated three-dimensional changes in the mandible and glenoid fossa of skeletal Class III patients treated with bone-anchored maxillary protraction. The results showed posterior displacement of the mandible and remodeling of the glenoid fossa, suggesting a favorable control of mandibular growth.
Researchers found that Fuz plays a crucial role in regulating craniofacial development, with defects leading to severe deformities. The study also highlights the importance of Fuz in negative feedback loops of canonical Wnt signaling.
A symposium at the International Association for Dental Research conference will present cutting-edge technologies to minimize caries damage and potentially eradicate caries disease. High-level evidence supporting new approaches will be discussed, including their potential effects on future healthcare costs.
A new study finds that a measure of HDL function, called cholesterol efflux capacity, is more closely associated with protection against heart disease than HDL cholesterol levels. Increasing efflux capacity was linked to decreased likelihood of coronary artery disease and improved cardiovascular health.
NIDCR funding to US dental schools decreased by 10% between 2005 and 2009, with dollars from other NIH Institutes and Centers increasing 34.6%. This trend may threaten the identity of dental schools as a profession if research infrastructure is not strengthened.
The new BD LSR-9 Flow Cytometer with its nine lasers will help Australian researchers analyze rare cell populations more accurately and directly. This technology will aid in fighting against various life-threatening diseases, including cancer and asthma.
Scientists have developed transparent thin films capable of absorbing light and generating electric charge over large areas. The material combines elements for light harvesting and electric charge transport, enabling potential applications in energy-generating solar windows and transparent solar panels.
Researchers at Penn School Medicine identified the steps controlling CD45 protein's different forms, essential for activating the immune system. The study's findings have implications for understanding autoimmune and neurological diseases.
The La Jolla Institute will host research projects throughout the San Diego biomedical community, exploring genetic triggers of disease and developing new therapies for cancer and other diseases. The Center is expected to propel immunology research and catalyze a broad base of basic and clinical investigations.
The international consortium's completion of the turkey genome sequence promises to provide new insights into avian genetics and improve turkey quality. The sequence will enable scientists to better understand specific genes important in meat yield, health, and disease resistance.
Insite, Vancouver's sanctioned supervised safe injection site, has been at odds with Canada's anti-drug policy since its opening in 2003. The facility's fate is uncertain, with the federal government appealing decisions to keep it open despite opposition from Conservative politicians.
A recent study suggests that Porphyromonas gingivalis (P.g.) infection may contribute to the chronicity of inflammatory disorders leading to oral cancers. The research found that P.g. induces expression of immune-regulating receptors B7-H1 and B7-DC in squamous cell carcinoma cells, facilitating immune evasion.
Researchers have successfully established induced pluripotent stem (iPS) cells from dental pulp cells, a potential source for regenerative medicine. The study found that these cells can be easily obtained and expanded under simple culture conditions, making them an attractive option for cell therapy approaches.
The National Institutes of Health (NIH) has awarded $1 billion in grants to construct, repair, and renovate scientific research laboratories across the US. These grants are expected to create or sustain jobs nationwide while fostering scientific advances that may lead to improved human health.
The 2010 IADR/GSK Innovation in Oral Care Awards recognized three researchers for their innovative work on antimicrobial coatings, citrus-based treatments, and point-of-care diagnostic tools. These awards will support the development of new technologies to prevent and treat oral diseases.
The HEALTHGRAIN Forum aims to promote science-based concepts for healthy cereal production, aiming to reduce healthcare costs and provide added value for companies. The new platform will facilitate knowledge sharing between academia, industry, and public bodies.
A study has identified genes that contribute to heart function and disease, shedding light on the genetic underpinnings of heart disease. The researchers found nearly 500 genes associated with heart problems in flies, including a protein complex called CCR4-Not.
A new Penn study reveals that nearly 135 million Americans are over an hour away from primary stroke centers, where timely treatment is crucial. The study suggests using medical helicopters to transport patients faster and proposes lower-cost solutions such as inter-hospital referral networks and telemedical technology.
Health care volunteers can make a disaster situation worse if they are not prepared. To optimize their response, they should seek formal training in disaster medicine and register with existing volunteer organizations. They should also consider the physical and emotional challenges of working in disaster areas and be mindful of the nee...
A team of researchers has discovered the mechanism behind Frank-Ter Haar syndrome, a rare fatal disorder that affects children's skeletal, cardiovascular, and eye health. The study identified TKS4 as a critical protein involved in the condition.
The National Science Foundation has awarded a $360,000 grant to establish a Robotics Crystallization Core Facility on the University of Oklahoma's Norman campus. The grant will provide sophisticated robotics equipment to support collaborative efforts among structural biologists in the state.
The UCLA School of Public Health has received a grant to establish a center focused on strengthening public health agency preparedness for natural and human-induced disasters. The new center will explore interorganizational cooperation, community-based partnerships, and environmental health emergency resilience.
The University of Alabama at Birmingham has been awarded $431,200 to acquire a highly-specialized X-ray Photoelectron Spectroscopy System with micro-scale-imaging capabilities. This will enable researchers to visualize surface chemical composition and bonding capabilities of newly designed materials.
The Fox Chase Cancer Center has received an $8 million grant to expand its laboratory animal research facility, enabling advanced research into cancer fundamental biological processes. The new facility will house mouse models for cancer research, facilitating the development of new treatments and improving research quality.
The Case Center for Synchrotron Biosciences will provide three Technology Cores to support the study of proteins and nucleic acids. The center's facilities will enable researchers to understand the structure and function of proteins, including in vivo studies, as well as investigate the role of metal atoms in proteins.
The NYU-HHC CTSI aims to leverage individual expertise, support education and training, and enhance community ties to promote evidence-based medicine and reduce healthcare disparities. With the grant, researchers will focus on discoveries in the lab that can be rapidly translated to the bedside and into communities.
Researchers studied effects of lighting interventions, stress and fatigue monitoring on crew performance. The 105-Day Mars Mission aimed to improve work performance in a realistic setting.
The National Institute of Allergy and Infectious Diseases has renewed funding for the 11 Regional Centers of Excellence, with a total of $455 million over five years. The centers will focus on developing countermeasures against emerging infectious diseases.
The University of Liverpool has been awarded £2.2 million to establish a high-throughput genomic analysis hub in the North of England, consolidating expertise from four partner universities to accelerate genetics research and personalized medicine. The hub will expand access to cutting-edge sequencing technology for researchers and cli...
Researchers test blue-white lamp prototypes to regulate sleep-wake cycles in people with dementia. The study shows promise in raising activity levels during daytime hours and increasing sleep at nighttime.
The new NHS Evidence service provides a fast and efficient web-based search facility to access a wide range of information on various topics. It also has a commissioning function to ensure knowledge gaps are filled and to provide central purchasing of online journals for staff in the National Health Service (NHS) in England.
Dr. Anthony Fauci, director of NIAID, receives IADR Honorary Membership for his significant contributions to dental research. The award recognizes his commitment to improving oral health worldwide.
The International Association for Dental Research (IADR) has awarded Lars Petersson with the 2009 E.W. Borrow Memorial Award for his original research and achievements in promoting children's oral health. The award recognizes Petersson's work in advancing knowledge to improve oral health worldwide.
The International Association for Dental Research (IADR) has awarded C. E. Semino with the JDR Cover of the Year Award for his paper on self-assembling peptides and their potential in bone regeneration. The award recognizes aesthetically pleasing and scientifically novel images that enhance research impact.
Dr. Fujio Miura receives the 2009 IADR Distinguished Service Award for his dedication to promoting JADR/IADR membership among young researchers in Japan, leading to significant growth in both Associations. The award recognizes his outstanding service and contributions to advancing dental research worldwide.
Andreas Niklas, a University of Regensburg Medical School student, has won the prestigious fellowship for his proposal on developing an in vivo optical measurement device. The $2,500 prize is supported by an endowment created by late IADR President David B. Scott's wife.
Dr. Mirela Shinohara, a young researcher from Brazil, has been awarded the 2009 Toshio Nakao Fellowship by IADR. The fellowship supports her training and experience in dental materials science at a center of excellence. IADR is a nonprofit organization dedicated to advancing research and improving oral health worldwide.
The 2009 William J. Gies Awards recognize outstanding papers published in the Journal of Dental Research. The awards were presented to E. Scheller et al., S. Paris et al., and A.E. Sanders et al. for their work on Wnt/β-catenin, resin infiltration, and psychological stress mediation in tooth loss.
Dr. Cun-Yu Wang is recognized for his groundbreaking research in cancer therapy and oral health, with a focus on molecular signaling, inflammation, and adult human stem cells. He joins an elite group of scientists honored by IADR for their contributions to advancing oral health knowledge worldwide.
Dr. Christopher McCulloch, a professor at the University of Toronto, is recognized for his significant contributions to understanding mechanisms regulating fibroblast cytoskeleton and collagen remodeling in periodontium.
Dr. Jeffrey Stansbury, a University of Colorado professor, has been awarded the IADR Wilmer Souder Award for his work on dental and biomedical polymeric materials. The award recognizes his research group's development of novel polymeric materials for various dental applications.
Dr. Athena Papas receives IADR's highest honor for her outstanding research on dry mouth, tooth sensitivity, and oral health in cancer patients. Her nearly 30-year career has secured over $20 million in grant funding.