A computer simulation found that health care facilities using a patient registry could reduce CRE spread by 15.5% over three years, even with modest participation rates. The study suggests that maintaining a registry can help contain the enemy of antibiotic-resistant bacteria.
A team at the University of Delaware has engineered a silicon-graphene device that can transmit radiofrequency waves in less than a picosecond, enabling faster communications. The device combines the benefits of silicon and graphene, with improved carrier mobility and electrical properties.
A new citizen science project, 'Science Scribbler - Virus Project', aims to train AI to identify virus particles by having people of all ages view screens and locate virus particles. This will help automate data segmentation processes, dramatically speeding up scientists' ability to understand research data in days rather than weeks.
A group of neuroscientists calls for balanced reporting on sports-related head injuries to better understand chronic traumatic encephalopathy (CTE) risk and prevalence. The medical community is still in the early stages of understanding CTE, with guidelines for assessment yet to be established.
A new study published in Science reveals that acetylcholine plays a critical role in combating chronic viral infections. Dr. Kevin J. Tracey and his team discovered that immune cells need acetylcholine to fight viral infections, providing a crucial new insight into bioelectronic medicine.
A new review of 28 scientific studies substantiates that changes in diet, prescription medications, and physical activity reduce food cravings. Losing weight and avoiding frequent eating of certain foods are proven strategies to manage cravings.
A meta-analysis of clinical trials found that home telemedicine programs for heart failure patients decrease mortality six months after hospitalization, but lose effectiveness after one year. The analysis also showed that these programs increase the odds of all-cause emergency room visits.
A study analyzed over 100,000 Yelp reviews to identify key themes in emergency department and urgent care center ratings. Emergency departments received high marks for bedside manner but low marks for speed of care, while urgent care centers excelled in ease of prescription refills but struggled with patient confidence.
The American Psychiatric Association and the American Telemedicine Association have released new best practices for videoconferencing-based mental health services, covering topics such as emergency situations, technical considerations, and patient selection. These guidelines aim to enhance the delivery of effective and safe telemental ...
A Pennington Biomedical Research Center study found that female mice on a high-fat diet given Russian tarragon or bitter melon supplements gained more weight and body fat compared to those not receiving the supplements. However, there was no significant change in insulin sensitivity or body-fat percentages.
Nephrologists and health policy experts advocate for greater transparency in joint-venture dialysis clinics to ensure patient referrals and clinical outcomes are not influenced by financial ties. The lack of disclosure poses a significant barrier to evidence-based research, depriving patients of critical information.
A new LSU Pennington Biomedical study reveals a novel biomarker that may help diagnose hypoglycemia-associated autonomic failure (HAAF) in diabetics. The biomarker measures how well the brain uses acetate, which could indicate if someone is at risk for developing HAAF or has already suffered from it.
The IADR Unilever Hatton Competition and Awards provide an opportunity for junior investigators to present their research, with up to six receiving monetary awards. This year's winners showcased innovative projects in head and neck cancer stem cells, oral cancer microenvironment, and dental treatment needs.
A new LSU Pennington Biomedical Research Center study suggests a novel biomarker may help create a diagnostic tool for hypoglycemia-associated autonomic failure. Measuring brain adaptation after low blood sugar episodes could detect increased risk of HAAF, allowing for targeted treatment.
A study analyzed 62 countries' DMTF Index scores, finding that those under Social Democratic and Liberal regimes had lower rates of tooth decay compared to Conservative and Dictatorial regimes. The researchers suggested creating new typologies to better characterize the relationship between political systems and oral health indicators.
A genome-wide association study identified novel risk loci for non-syndromic orofacial clefts in an African population, refining the genetic architecture of the condition. The study also revealed new genetic associations with cleft lip and palate sub-phenotypes.
Researchers have developed a new method to measure pocket depths in periodontal disease using photoacoustic imaging and ultrasound. The technique offers high precision and covers all areas of the tooth, outperforming traditional probing methods.
The DEEP study examined the costs and quality-of-life of individuals with persistent orofacial pain (POFP) and estimated outcomes from pain onset. The results showed that high pain levels led to increased healthcare costs and decreased quality-of-life, highlighting the burden of POFP on health.
A new trial found that 5% sodium fluoride varnish is not more effective than other treatments in reducing cavities among preschool children. The study tested two different solutions and showed mixed results.
A recent study found that Programmed Cell Death-1 (PD-1) is crucial for the self-renewal and differentiation of dental pulp stem cells. Removal of PD-1 from these cells led to reduced proliferation rates, highlighting its importance in maintaining stem cell function.
The symposium highlighted new discoveries about oral exRNA biology, providing insights into saliva's unique fraction of exogenous RNA. Researchers discussed leveraging salivary extracellular RNA to improve research and practice in the field of dental and oral health.
Non-syndromic Dentinogenesis Imperfecta is characterized by discolored teeth with a blue-gray or yellow-brown color and translucent appearance. Chronic Unfolded Protein Response (UPR) may be associated with the disorder, caused by mutant dentin sialophosphoprotein (DSPP) gene mutations.
A study found that perinatally HIV-infected youth on integrase inhibitors have a higher risk of dental caries. The study also showed that initiating protease inhibitors at age six or older is associated with less gingival inflammation and lower DMFT scores.
The BioMaker Lab at the University of Illinois will accelerate research on advanced biological materials, providing state-of-the-art tools for characterization and fabrication. The lab is expected to drive innovation in biomedical technologies and empower students with top-notch educational opportunities.
The Council of Academic Family Medicine Educational Research Alliance has increased family medicine's research productivity and faculty participation, including scholars with less experience. The CERA model can be replicated in other specialties to facilitate collaborative research.
INRS is awarded over $1.57 million to support four promising research projects focused on ecotoxicogenomics, high-speed bio-imaging, synaptic dysfunction in motor neuron diseases, and quantum materials
The Midlands Regional Cryo-Electron Microscope (Cryo-EM) Facility brings cutting-edge research technologies to the region. The £6M facility will enable scientists to study bio-molecules in exquisite detail, leading to a better understanding of disease processes and how to address them.
Researchers at the University of Edinburgh will pool anonymised health records, genetics, and psychological studies to better understand mental health conditions like depression. The £2.2 million initiative could lead to new treatments and improved resilience for one in four people in the UK who experience a mental health issue annually.
Researchers question the longstanding guidelines for fluoride intake, citing changes in sources and prevalence of dental caries and fluorosis. The symposium highlights research gaps, including measuring total fluoride intake and evaluating its effects on children and adults.
The study found that genes responsible for repairing spinal cords in fish, such as the lamprey, are also present and active in mammals, including humans. This discovery could lead to new therapeutic approaches for spinal cord injuries in humans.
Researchers from six centers worldwide have assembled a vast family dataset to study genetic contributions to common epilepsies. The study reveals distinct family syndromes that could inform future genetic research and treatment development.
A recent study published in Molecular and Cellular Biochemistry found that brain cells contain less polyunsaturated fatty acids compared to other major organs. This discovery, made by Dr. Junhwan Kim, PhD, has significant implications for understanding brain health and conditions like oxygen deprivation.
A Science DMZ architecture can be adapted to meet the needs of the medical research community, allowing for secure sharing of large datasets while protecting individual privacy. The design provides speed and security for moving large data sets, enabling teams of experts to collaborate in real-time.
A new universal surveillance platform is being developed to detect infectious diseases, using Ceres' Nanotrap technology and Tasso's HemoLink device. The platform aims to provide safe and simple blood sample collection in remote environments, improving early response to outbreaks.
The American Association for Dental Research (AADR) suggests that dental schools prioritize research participation, collaboration with other departments, and flexible curricula. AADR also advocates for increased funding from various sources, including the National Institutes of Health, to support dental research and training.
Researchers at Berkeley Lab and UC Berkeley have developed a new mechanism to attach radioactive fluorine atoms to chemical compounds, expanding medical imaging capabilities. This breakthrough enables the creation of new 'radiotracers' for PET scans, which can aid in detecting cancers and understanding biological pathways.
A protein called Blimp-1 regulates the immune system in patients with lupus, leading to an overactive immune response that attacks healthy tissue. The study's findings suggest a link between low Blimp-1 levels and increased risk of lupus in females.
Dr. Ravetch's research on Fc Receptor Biology has led to a deeper understanding of the fine line between healthy immune reactions and autoimmunity, paving the way for new therapies for infectious, neoplastic, and inflammatory diseases.
Hepatitis C patients with substance use disorders face barriers to care, including lack of access to conventional healthcare and fear of stigmatization. Innovative approaches, such as integrated screening and treatment in methadone clinics and telehealth techniques, are being developed to improve outcomes for this population
Researchers at Caltech have discovered the molecular basis for protection of a ribosomal protein from cellular degradation, using X-ray crystallography to solve the structure of the bound pair. This finding has potential applications in developing new cancer drugs by preventing tumor growth.
The Southwest National Primate Research Center at Texas Biomedical Research Institute has received a $40 million NIH grant to continue its research programs using nonhuman primates. The grant renewal will support the Center's breeding and research colonies of NHP species, making them available to the global scientific community.
The VA healthcare system generally delivers safe and effective care similar to other health systems, with some exceptions. However, studies on timeliness, equity, efficiency, and patient-centeredness show mixed results.
The US Veterans Health Administration is implementing various changes to improve LGBT care, including the addition of a self-identified gender identity field to all veteran record systems. These actions aim to provide patient-centered care for sexual and gender minority veterans.
A study found that annual application of SDF solution arrests root caries in community-dwelling elders, with higher effectiveness in non-fluoridated areas. The background water fluoride level had no statistically significant influence on the effectiveness of SDF.
Fluorides are effective in preventing caries, but their use alone cannot prevent the disease when combined with high sugars diets. The effects of reducing sugars intake are modified by fluoride, but the two approaches can work synergistically to reduce caries activity.
The OPPERA study reveals that jaw injuries are strongly associated with temporomandibular disorder (TMD), with increased incidence rates found for extrinsic events, sustained mouth opening, and yawning. Single injuries were sufficient to increase risk of developing painful TMD.
The IADR/AADR published an issue on International Caries Consensus Collaboration's (ICCC) recommendations for managing carious lesions, focusing on evidence-based, patient-centered guidelines. The recommendations support less invasive carious lesion management by preserving tooth tissue and retaining teeth long-term.
Researchers have successfully developed a new treatment for the deadly Junin virus, providing complete protection against the disease. The laboratory-engineered antibody demonstrated effectiveness in guinea pigs and showed promise as a therapeutic solution for patients.
A recent study by University of California, San Diego School of Medicine reports that educating Community Health Workers (CHWs) and other 'citizen scientists' can boost the integrity of scientific research. The Building Research Integrity and Capacity (BRIC) program uses eight modules to teach research ethics and concepts.
The IADR/AADR have released the first issue of JDR Clinical & Translational Research, a journal focusing on the translation of research into clinical practice. The inaugural issue covers various topics in applied oral health research, with an emphasis on rapid dissemination and application.
Researchers estimate US periodontitis prevalence at state and local levels using a novel SAE method, revealing high risk areas in the southeast and southwest, including Native American reservations. The study informs oral health policy decisions and intervention strategies to increase access to care for populations at higher risk.
The Iris and Junming Le Foundation has donated $500,000 to support the purchase of a powerful super-resolution microscope at Scripps Florida. This advanced technology will enable neuroscientists to see synapses between neurons with unprecedented detail, potentially leading to breakthroughs in Alzheimer's disease research.
A recent study found that a higher monetary cost of dietary intake is associated with improved diet quality, increased fruit and vegetable consumption, and weight management. The researchers monitored 2181 Spanish adults for ten years and discovered that spending more on food led to better health outcomes.
New evidence on dental implants reveals the importance of tooth preservation in patients with gum infections. The studies suggest that teeth compromised by periodontal disease or endodontic problems may have a longer longevity than average implants.
A study of 1,280 patients with myelodysplastic syndrome (MDS) found comparable survival rates at 100 days and two years for those aged 65 and older compared to younger patients. Age was not a determining factor in HCT outcomes, with marrow blasts, cytogenetics, and Sorror co-morbidity scores being independently associated with results.
A large-scale national study on people with dementia in residential aged care found that participants experienced low levels of activity participation and pessimistic attitudes from staff and families. The study suggests improving leisure activities could enhance quality of life for those with dementia living in long-term care.
A new Ebola vaccine has been found to be well-tolerated and stimulate strong immune responses in adults in Mali and the US. The study's findings could offer crucial protection for contacts of patients with confirmed Ebola disease, helping to interrupt transmission.
The Cornell NanoScale Science and Technology Facility will receive $8 million from the National Science Foundation over five years. This grant, combined with a matching commitment from New York state, will provide long-term infrastructure support for ambitious research.
Smiling Brazil launched in 2004 and incorporated oral health into the public healthcare system, adopting an integral care approach. The policy has shown positive results in oral health epidemiological indicators, financial investment, and professional development.
Recent studies published by the International Association for Dental Research (IADR) highlight the significant link between sugar intake and dental caries. The findings emphasize that even low sugars intakes can contribute to the development of caries, underscoring the need for effective health policies.