Articles tagged with Biomedical Research Funding
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers aim to understand how HIV affects cardiovascular health and the impact of substance use on this relationship. They plan to develop a human bone marrow chip model to study HIV pathogenesis and explore potential strategies for caring people with HIV who face cardiovascular disease.
Charité is leading four new EU projects tackling environmental impact on mental health, developing a cell therapy for IgA nephropathy, and improving AI-assisted stroke care. The projects aim to advance research and innovation in these areas.
Researchers from Bern and Geneva universities will receive $878,000 in funding to investigate mechanisms of resistance to PARPi inhibitors in BRCA-mutated ovarian cancer. The goal is to develop new targeted therapies to improve survival rates for patients with drug-resistant ovarian cancer.
Researchers will track changes in the blood-brain barrier, neurovascular function, and cognition in over 850 participants with genetic variants at risk of developing Alzheimer’s disease. The study aims to improve understanding of the onset and progression of Alzheimer’s disease and identify effective interventions.
The INCLUDE Data Hub provides centralized access to large-scale research resources, including biospecimen libraries and clinical datasets, for the study of Down syndrome. With over 8,000 study participants and 30,000 biospecimens, researchers can accelerate discoveries that benefit people with Down syndrome.
Researchers are assessing cognitive decline in aging Latinos, exploring the long-term impact of COVID-19 and cardiovascular disease on brain function and impairment. The study will gather data to develop real-world therapies and potentially lessen the disease burden of dementia affecting Latinos.
A team of engineers is working on a novel treatment using nanoparticles carrying therapeutic proteins to promote regeneration of blood vessels and muscle in injured limbs. The approach, which has shown promising results in animal models, aims to treat critical limb ischemia, a condition that can lead to amputation or death.
The five-year DIASIRE summer program will accept eight to 10 undergraduate students from across the country, providing them with valuable research skills and mentorship from OHIO faculty. Students will learn about the history and pathophysiology of diabetes, as well as epidemiological, social, and molecular/cellular research efforts.
Researchers at Keck School of Medicine of USC are testing the efficacy of 3K3A-APC as a cerebroprotectant to reduce brain bleeds in acute ischemic stroke patients. The experimental drug has shown promising results in Phase 2 clinical trials, reducing incidence of brain hemorrhage by nearly 20%.
Researchers at West Virginia University are studying the mechanisms behind Alzheimer's disease and PTSD, using animal models to investigate how stressful events affect brain cells. They aim to understand the role of estrogen and high-cholesterol diet in developing the disease.
The University of Minnesota has received a $66 million grant from the NIAID to establish a center for developing antiviral drugs for pandemic-level viruses, including SARS-CoV-2. The Midwest Antiviral Drug Discovery Center will bring together investigators from the University and sixteen other institutions nationwide.
Researchers at Marshall University Joan C. Edwards School of Medicine are studying the role of obesity and oxidative stress in Alzheimer's disease. Obesity is a key predictive factor for Alzheimer's disease, which affects 14 million Americans by 2060.
The partnership aims to accelerate projects targeting the most dangerous bacteria. Since its founding, CARB-X has awarded $361 million to 92 projects from 12 countries.
The Mount Sinai Microbiome Lab will use advanced methods to study the microbiome's role in autoimmune diseases such as rheumatoid arthritis and systemic lupus. The lab aims to identify microbial features that can help find more precise matches between diseases and treatments.
The UTMB-Novartis Alliance for Pandemic Preparedness will focus on coronaviruses, flaviviruses, and henipaviruses with pandemic potential. The partnership aims to develop safe and effective antiviral drugs against emerging pathogens like SARS-CoV-2.
Two Medical University of South Carolina epidemiologists investigate how COVID-19 disruptions affected pregnancy outcomes, particularly for racial and ethnic minority communities. They aim to determine whether pandemic-caused disruptions worsened already poor maternal and infant health statistics.
A new analysis of nationally representative data reveals a significant increase in the impact of HPV vaccination efforts, leading to decreased prevalence of cancer-causing HPV infections among both vaccinated and unvaccinated females. The study found that vaccination has directly protected individuals and generated herd effects, reduci...
Researchers are developing a novel MRI nanotechnology that targets specific markers in solid tumours, including high-grade brain cancers. The new imaging technology has shown promising preclinical results and is set to be tested in a first-in-human clinical trial.
The Center of BioModular Multi-Scale Systems for Precision Medicine develops rapid next-generation tests for human ailments like cancer and COVID-19 using saliva, urine, or blood samples. The technology has already helped patients through commercial partnerships with private firms.
The new center aims to advance a groundbreaking combination of focused ultrasound and cancer immunotherapy, potentially revolutionizing cancer treatment. The partnership will focus on overcoming existing limitations of immunotherapy and expanding treatment options for various types of cancer.
A new study found that states with higher funding for public health programs reported more foodborne illnesses and were better equipped to investigate them. The researchers hope their findings will lead to increased investment in public health programs nationwide.
A $66,000 NIH grant will support Karry Weston's two-year study on the lack of breastfeeding in rural Missouri. The goal is to identify cultural factors influencing mothers' decisions, with a focus on improving maternal care in rural communities.
A new $1.25 million NIH grant provides teaching resources and professional development for middle school teachers to boost disciplinary literacy skills and interest in science, technology, engineering, and math (STEM) subjects. The program aims to help traditionally underrepresented groups feel confident about potential careers in STEM.
The new COBRE grant will help WVU recruit researchers and clinician-scientists to develop innovative solutions for preventing and treating incurable vision problems. The project aims to reduce visual disparities in West Virginia by understanding the complex combination of factors that contribute to these problems.
The University of Texas at El Paso has received a $5M NIH grant to build an imaging and behavioral neuroscience facility focused on addressing Hispanic health disparities. The new facility will enable researchers to study the mechanisms contributing to cancer and neurological disorders in Hispanic populations.
The program aims to increase trained cancer researchers in Tanzania and prepare them for HIV-associated cancer diagnostics, genomics, and therapy. It will focus on molecular detection, epidemiology, and biology of common HIV-associated malignancies.
Six TUD researchers have been awarded extensive EU funding for their innovative projects, with a total value of over 7 million euros. Prof. Triantafyllos Chavakis and his team are investigating metabolic inflammation, while Prof. Stefan Kaskel's project aims to develop ion-based computer technologies that reduce energy consumption.
The Max Delbrück Center researcher is investigating the mechanism of how the heart responds to environmental factors and adjusts its elastic properties. He plans to develop technologies for single-cell mechanics, -transcriptomics, -proteomics to enable higher rates of throughput for multi-omics approaches.
A team of UTHealth Houston researchers has been awarded a $2.85 million NIH grant to study a new technique assessing cerebrospinal fluid in babies with hydrocephalus, which affects 400,000 newborns globally each year.
Rice University and MD Anderson Cancer Center will train future medical professionals to translate nanotechnology advances to the clinic, focusing on cancer diagnosis and treatment. The five-year program aims to recruit 16 fellows from underrepresented groups.
A new study by Ohio State University researchers found that federal research funding has a positive 'ripple effect', stimulating investigations in new areas and providing unexpected benefits. The study showed that funding mostly goes to hiring people who work on the projects, leading to an increase in productivity and quality of research.
New research suggests that ADCC responses and strain susceptibility influence HIV-1 mother-to-child transmission during breastfeeding. Enhancing ADCC through a vaccine may not be sufficient to prevent transmission due to chronically infected individuals' ADCC-resistant strains.
A biomedical engineering researcher will create a combined 'nasal airway and lung-on-a-chip' platform to mimic the upper and lower respiratory system. The AirLOC model will simulate exposure to particulate matter pollution, replicating complex organ functions and tissue interactions.
A five-year, $13 million grant will investigate the molecular and cellular mechanisms of prion transmission in CWD. The researchers aim to understand the inter-species transmission potential of the disease and its ability to spread from animals to humans.
Dr. Kenichi Miharada and his team received the grant to develop an in vitro red blood cell production method due to global blood shortage for transfusions. They have already established a semi-infinitely proliferating red blood cell source called immortalized human erythroblast cell line (ELLU cells), but face technical challenges.
A new study published in PLOS ONE finds that high and very high cardiovascular risk are associated with depressive symptoms, especially in women. The researchers used data from a Mediterranean Diet trial and found that participants with higher cardiovascular risk had lower depressive status scores after following the diet.
The TTUHSC's C. Patrick Reynolds has received a $1.34 million CPRIT grant to investigate updating the clinical risk stratification scale for neuroblastoma and rhabdomyosarcoma, two childhood cancers in need of improved therapies.
The NIH has awarded grants to four institutions to establish Tuberculosis Research Advancement Centers, which will provide focused mentoring, funding support, and training opportunities for new investigators. The centers aim to develop a next-generation of tuberculosis researchers and alleviate the global burden of TB through research.
The University of Cambridge has been awarded a £3.67m Critical Mass Grant to advance its world-leading research on dynamical phenomena in condensed matter physics. The grant will support the development of new theoretical models that capture and explain experimental properties, making testable predictions about new phenomena.
Researchers at Northwestern University used CRISPR to identify human genes important for HIV infection in blood cells, finding 86 genes that may play a role in replication and disease. The study proposes a new map for understanding how HIV integrates into the DNA and establishes chronic infections.
Scientists have discovered a shapeshifting volcano virus with remarkable properties that let it alter its shape. This finding could lead to new ways to deliver drugs and vaccines, with implications for understanding how viruses evolved and potentially creating new technologies.
A new wireless implant has the potential to treat neuropathic pain resistant to medical therapy, offering a minimally invasive alternative to surgery. The device uses bioelectronic therapy to stimulate peripheral nerves from within blood vessels, providing precise placement and predictable outcomes.
H. Alex Choi receives NIH grant to develop protein biomarkers for delayed cerebral ischemia, a complication after subarachnoid hemorrhage that affects approximately 50,000 Americans annually. The goal is to predict which patients will worsen and identify biological processes causing worsening patients.
Dr. Elaine S. Jaffe is being recognized for her pioneering work in hematopathology, including the discovery of novel pathological entities and her development of standardized diagnostic criteria for lymphoma and leukemia. She has also made significant contributions to advancing cancer research, diagnosis, treatment, and prevention.
Researchers at UVA Health System discovered a cluster of cells in the brainstem that controls the body's response to severe blood loss. The study found that re-activating these neurons can restore blood pressure and heart rate in lab rats, offering new hope for treating traumatic injuries.
Researchers at TTUHSC will investigate common mechanisms of resistance and sensitivity in alternate telomere lengthening (ALT) cancers, with a focus on targeting ATM kinase inhibitors for therapy. The team aims to develop clinical trials for patients with ALT+ cancers.
A study found that female principal investigators led fewer trials and those funded by industry sponsors, but more trials led by women were associated with higher enrollment of female subjects. This highlights the need for increased female representation in clinical trial leadership.
The Texas Tech University Health Sciences Center has received a five-year, $1.87 million NIH grant to investigate the role of vitamin A depletion in Alzheimer's disease. The research aims to test the hypothesis that a lack of antioxidant all-trans retinoic acid (ATRA) promotes reactive oxygen species toxicity.
Autophagy is induced when ER-bound ribosomes are stalled, rescuing them from cellular harm. The ERC grant aims to decipher the role of Autophagy in rescuing stalled ER-bound ribosomes.
Researchers at the University of Huddersfield have identified a key mechanism by which the coronavirus causes inflammation in the brain's immune cells, potentially explaining some symptoms experienced by COVID-19 patients. The study suggests that adequate funding is needed to further develop this research and its potential applications.
Researchers at Weill Cornell Medicine found that certain Candida albicans yeast strains produce a potent toxin called candidalysin, which damages immune cells and triggers pro-inflammatory responses. The study suggests a possible way to personalize treatments for IBD patients by targeting these high-damaging strains.
The Southeastern Consortium for Lung Cancer Health Equity aims to address disparities in lung cancer screening among racially and ethnically diverse populations. Researchers will develop more precise methods for identifying those at highest risk of lung cancer diagnoses.
A randomized study of 379 women with obesity and unexplained infertility found that intensive lifestyle changes that shed pounds led to no better chances of pregnancy than simply increasing physical activity without weight loss. The study also showed significant health benefits from weight loss, including a decrease in metabolic syndrome.
Lab tests show antiviral therapies like remdesivir, molnupiravir, and nirmatrelvir remain effective against the BA.2 variant. Some monoclonal antibodies, such as Evusheld, also appear to be more effective against BA.2 than earlier strains.
Dr. Zhiqiang Lin has been awarded a $3.2 million NIH grant to investigate the roles of YAP and IRF2BP2 in the cardiac innate immune response, with the goal of reducing cardiac inflammation and promoting heart recovery after a heart attack.
Researchers at the University of Virginia Health System have identified a potential way to treat obesity and type 2 diabetes in women by targeting a specific gene called KLF14. Increasing KLF14 abundance in fat cells may help alleviate metabolic abnormalities, including slower metabolic rates and less efficient triglyceride management.
The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors approved funding for 12 new comparative clinical effectiveness research studies focusing on maternal health, autism, and urinary incontinence. These studies will improve healthcare delivery and health outcomes in real-world settings.
Economists Ed Timmons and Conor Norris suggest reforms such as shorter medical school pathways, expanded physician assistant and nurse practitioner independence, and federal regulation of telemedicine to alleviate the healthcare industry's stress in light of COVID-19. These proposals aim to address staffing shortages, improve access to...
A new study found that a ketogenic diet significantly improves MS symptoms, including fatigue, depression, and cognitive function. Patients on the keto diet experienced reductions in neurologic disability and enhanced overall quality of life.
Robert Gourdie, a cardiovascular scientist at the Fralin Biomedical Research Institute at VTC, has been awarded an R35 grant from the National Heart, Lung, and Blood Institute. This seven-year, $6.4 million grant enables him to pursue research on intercellular communication and its applications in treating various medical challenges.