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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Douglas study on neurogenesis in the olfactory bulb

Researchers found that integration of new neurons in the adult brain is compromised in depressed patients, particularly in the olfactory bulb. This discovery provides an important step towards understanding the mechanisms of depression.

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Sense of smell may reveal weight bias

Researchers found that visual cues associated with overweight people influence one's sense of smell, and participants with higher BMI tend to be more critical of heavier individuals. This study suggests that weight stigma may be more pervasive than previously thought, affecting everyday life in various ways.

Leaf odor attracts Drosophila suzukii

Scientists at the Max Planck Institute for Chemical Ecology identified a leaf odor, beta-cyclocitral, that specifically attracts Drosophila suzukii, a devastating fruit crop pest. This specialization allows the fly to pinpoint ripe fruits by tracking the distinct leaf odor.

Understanding how neurons shape memories of smells

Researchers discovered a type of neuron in the olfactory cortex that serves as a tuner and volume control for various neuronal inputs, increasing signal-to-noise ratio and improving odor discrimination. This discovery has implications for understanding epilepsy, which often affects the olfactory cortex.

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Things smell good for a reason

Researchers at the Max Planck Institute for Chemical Ecology discovered that fruit flies can detect antioxidants using olfactory cues, increasing feeding behavior and triggering oviposition. This form of detection is not unique to insects, as humans also perceive pleasant odors from healthy nutrients.

Trust through the olfactory fragrance of lavender

Researchers found that exposure to lavender aroma significantly increased money transfer between test persons in a trust game. The study suggests that smelling lavender may help establish trusting negotiations and build team spirit in various situations.

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Neurons that detect disease

A study by the University of Geneva reveals how mice avoid their sick peers through the detection of specific olfactory signals by the vomeronasal system. This neural mechanism allows rodents to recognize and avoid diseased individuals, providing a new understanding of social behavior and innate defense strategies.

How the brain can distinguish good from bad smells

Researchers at the Max Planck Institute found that a brain region called the lateral horn can categorize odors as good or bad and weak or strong. This ability is similar to the function of the amygdala in vertebrates, which evaluates sensory impressions and dangers.

The sense of smell uses fast dynamics to encode odors

Researchers use light to control neurons in genetically-engineered mice, allowing for precise detection of odor dynamics. Mice demonstrate ability to discriminate between dynamic activities, suggesting neural population dynamics play a crucial role in the sense of smell.

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Scientists sniff out unexpected role for stem cells in the brain

Researchers found that newly formed brain cells in the olfactory system maintain proper connections and are essential for recovery from disrupted states. The discovery challenges previous assumptions about neuronal development and suggests a constant supply of new neurons is necessary to stabilize the mature structure.

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Decreased ability to identify odors can predict death

A study published in PLOS ONE found that older adults who failed a simple smelling test were more likely to die within five years. The researchers found that olfactory dysfunction was a stronger predictor of mortality than chronic diseases like heart failure and cancer.

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Foul fumes derail dinner for hungry moths

Researchers found that natural plant odors and human sources of pollution can conceal the scent of sought-after flowers, leading to energy and time losses for pollinators. The study used a chemical detection device to track flower odors in the wild and showed remarkable similar results in a lab wind tunnel test.

Decoding characteristic food odors

Researchers identify 230 key odorants responsible for encoding the typical smell of individual foodstuffs, with each foodstuff having its own unique odor code. The mapping of odor codes opens up new possibilities for biotechnology applications in crop breeding and industrial-scale production of high-quality food odorants.

When wine hits the right nerve

Researchers at Ruhr-University Bochum decode mechanism for appreciation of the barrique character, a bitter sensation on the tongue. They found that gallic acid groups are responsible for triggering this sensation, which is mediated by the trigeminal nerve.

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Wiring for smell sets up early, then persists

Brown University scientists found that the fundamental neural wiring map between the nose and brain becomes established in early development and remains unchanged throughout life. The study's findings provide insight into neurodevelopmental disorders and may have implications for regenerative medicine.

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The first insects were not yet able to smell well

Insects' sense of smell crucial for survival; recent study shows odorant receptors emerged long after terrestrial adaptation. The first insects were not yet able to smell well, with their complex olfactory systems evolving after the development of flying ability.

Humans can distinguish at least 1 trillion different odors

Researchers have found that humans are capable of discriminating between an vast number of complex odors, with estimates suggesting at least 1 trillion possible scents. This new understanding challenges the long-held assumption that humans can only detect around 10,000 different smells.

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Mechanism elucidated: How smell perception influences food intake

Researchers discovered that CB1 cannabinoid receptors control a circuit connecting the olfactory bulb to the olfactory cortex, increasing sensitivity to smell during hunger. This biological mechanism may be altered in obese or anorexic patients, enabling better management of these pathologies.

Long distance signals protect brain from viral infections

Researchers have discovered that cells in the olfactory bulb release signaling molecules that trigger anti-viral interferon production in uninfected brain regions, preventing virus spread. The study shows promising potential for understanding and treating brain-infectious diseases.

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Humans can use smell to detect levels of dietary fat

Researchers at Monell Center found humans can differentiate levels of dietary fat in food using the sense of smell. Innovative methods could make low-fat foods more palatable and aid in reducing excessive fat consumption.

Extensive variability in olfactory receptors influences human odor perception

A new study by the Monell Center found that humans have a unique array of olfactory receptors, which encode both intensity and quality of odors. The researchers discovered considerable variation within the genes for discrete receptors, with approximately 140 receptors differing in response to odor molecules between any two individuals.

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Swarming insect provides clues to how the brain processes smells

Researchers used locusts to demonstrate how the brain processes multiple odors simultaneously, recognizing patterns and adapting to new cues. The findings shed light on principles of olfactory computation and have potential applications in medical diagnostics and non-invasive chemical sensing.

A shot of anxiety and the world stinks

Researchers discover how anxiety affects olfactory processing, linking emotional centers of the brain. Neutral smells become distasteful under anxiety, leading to a vicious cycle that can heighten distress and lead to conditions like anxiety and depression.

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Mosquitoes smell you better at night, study finds

Researchers found that mosquitoes have higher olfactory sensitivity and protein abundance of odorant-binding proteins (OBPs) at night, making them more effective at detecting human hosts. This discovery has significant implications for developing novel insect control methods to reduce malaria transmission.

We each live in our own little world -- smellwise

Researchers found genetic associations for four odors: malt, apple, blue cheese, and β-ionone. The study suggests that individual sensitivities to these compounds determine unique smells experienced in foods and drinks.

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Age-related smelling loss significantly worse in African-Americans

Research reveals African-Americans have a greater decline in their sense of smell as they age, which can lead to impaired nutrition and increased risk of neurodegenerative diseases. The study found that racial disparities in olfactory function cannot be explained by social, environmental or medical factors.

An electronic nose can tell pears and apples apart

A team of engineers from Sweden and Spain has developed an electronic nose with 32 sensors that can identify the distinct odors of pears and apples. The device uses metal oxide semiconductors to detect volatile compounds and processes data through classification algorithms.

Cat and mouse: A single gene matters

A Northwestern University study shows that removing one olfactory receptor from mice can have a profound effect on their behavior, highlighting the importance of individual genes in sensory perception. The research reveals that a single gene, TAAR4, is necessary for mice to avoid predators based on the scent marks of carnivores.

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Developing our sense of smell

Researchers at Caltech have found that neural-crest stem cells differentiate into microvillous neurons, which sense pheromones, and are distinct from ciliated neurons that detect volatile scents. The discovery sheds light on how olfactory neurons form and may lead to new treatments for conditions like anosmia.

Transistor in the fly antenna

Researchers at the Max Planck Institute for Chemical Ecology discovered that insect odorant receptors are self-regulated, allowing them to amplify sensitivity in response to below-threshold odor stimulation. This mechanism enables flies to detect minute amounts of odors, essential for navigation and finding resources.

Evidence that at least 1 mammal can smell in stereo

A study by Kenneth Catania at Vanderbilt University has found that common moles rely on stereo sniffing to detect odor gradients, a skill previously thought to be limited to visual and auditory perception. This discovery opens new avenues for research into the capabilities of other mammals that heavily rely on their sense of smell.

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Grooming helps insects keep their senses sharpened

Researchers at North Carolina State University found that insect grooming, particularly antennal cleaning, helps maintain sharp olfactory senses. Grooming removes both environmental pollutants and chemicals produced by insects themselves, enabling them to detect food, danger, and potential mates effectively.

Helping the nose know

Researchers describe how feedback mechanism works by identifying where signals go and which neurons receive them. The study reveals that higher brain regions communicate with lower parts of the brain on a near-constant basis, helping to interpret olfactory information.

Moths wired two ways to take advantage of floral potluck

Researchers discovered that moths use two distinct olfactory channels to navigate their food sources. The first channel governs their innate preferences for certain flowers, while the second allows them to learn about alternate sources of nectar. This study provides insights into how moths survive in changing floral environments.

Animals learn to fine-tune their sniffs

Researchers found that animals can adjust their sniffs to target specific odors in complex blends. The study showed that rats learned to detect highly absorbent odors more quickly than less absorbent ones, highlighting the importance of physical properties and sniffing techniques in olfaction.

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Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.