Researchers found decreased alpha-2 integrin expression predicts tumor dissemination and lower survival rates in breast and prostate cancer. Alpha-2 integrin suppression of metastasis was confirmed using a mouse model and human microarray databases.
A study by Young and Rice found that online social networking has both positive and negative effects on sexual risk behaviors in homeless youth, with potential for increased risks but also opportunities for effective health communication and information portals.
Dr. George W. Sledge Jr is a pioneer in developing novel therapies for breast cancer. His work has improved the lives of countless cancer patients through anti-angiogenic therapy and molecular studies.
Research published by the American Academy of Neurology found that women who experience RLS during pregnancy are four times more likely to develop the condition again and three times more likely to have a chronic form. Symptoms may reappear later on in life or in future pregnancies.
Researchers measured carbon dioxide fluxes in the North Atlantic using an autonomous system, making nearly 4,000 flux measurements. The study found that formation of bubbles in breaking waves may increase gas transfer at high wind speeds.
The University of Manchester has established the UK's first Centre for Doctoral Training in Computer Science, receiving a £2.2m grant from EPSRC. The centre will admit at least 75 students over five years and provide training in research problem-solving, collaboration with industrial users, and real-world impact.
Research on over 28,000 children found that prenatal exposure to mobile phones was associated with an increased risk of behavioral problems. Children exposed to mobile phones before and after birth were 50% more likely to exhibit abnormal behavior.
Research by Penn State and University of Gothenburg found that brand named hotels outperformed independent hotels in economic downturns. Branded hotels registered significantly higher net operating income during recessions due to increased occupancy, while independent hotels charged higher room rates due to perceived uniqueness.
A new Confocal Laser Endomicroscope (CLE) tool allows clinicians to view bacteria that trigger bowel diseases like Crohn's and ulcerative colitis during routine colonoscopy. This enables rapid identification of patients at risk or in early stages of these diseases.
Research from the University of Gothenburg reveals that cyanobacteria like Nodularia spumigena become more toxic when facing eutrophication conditions, producing hepatotoxin nodularin. This toxin attacks the liver, posing a risk to humans and livestock consuming contaminated water.
A Yale University study found that LGB adolescents are 40% more likely to be punished by school authorities, police, and the courts. Girls who identified as lesbian or bisexual were especially at risk for unequal treatment, with twice as many police stops, arrests, and convictions.
A recent study has identified DEDD protein as essential for the formation of a functional decidua in mice. Defective DEDD function may be responsible for female infertility. The researchers suggest further investigation into the relationship between DEDD dysfunction and infertility in women.
A comprehensive study published in BioScience reveals over 455 insects and 16 pathogens are destroying forests across the US. Invasive species are predicted to continue threatening native ecosystems, with experts warning of a devastating impact on industries dependent on trees and plants.
The personalized vaccine is effective in preventing recurrence among certain follicular lymphoma patients with a specific protein on their tumor cells. The vaccine improves disease-free survival by nearly two years compared to placebo treatments.
Researchers at Mayo Clinic found that JAK inhibitors CYT387 and TG101348 effectively reduce spleen size and alleviate constitutional symptoms in myelofibrosis patients. These targeted treatments have shown significant clinical benefits, including improved anemia rates and reduced white blood cell counts.
Carnegie Mellon University has launched a new center for climate and energy decision making, developing strategies to protect fragile ecosystems and curb carbon emissions. The center will also educate graduate students on climate change and its impact on the environment.
Researchers found that marmots' social behavior has a genetic component, with aggression tolerance and friendly interactions heritable traits. The study, led by UCLA biologists, used social network statistics to analyze the behavior of yellow-bellied marmots over six years.
A study of 3610 Australian women found that social norms play a significant role in promoting physical activity and healthy eating behaviors. Women who surrounded themselves with friends who engaged in healthy behaviors were more likely to adopt similar habits.
A recent study has found that high blood pressure is more common among black women in the southeastern US compared to white men. The researchers analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) study and discovered significant geographic, racial, and gender differences in hypertension risk.
Researchers have discovered a class of molecules that can target quorum sensing, a key mechanism used by bacteria to communicate and coordinate their behavior. By blocking this system, scientists hope to develop new drugs that can prevent bacterial infections without promoting resistance.
Six scientists from Croatia, Czech Republic, Poland, Portugal, and Turkey will receive the 2010 EMBO Installation Grants for 3 years. They will be integrated into the prestigious EMBO Young Investigator programme with networking opportunities and career development programmes.
Scientists have developed a novel flu vaccine using bacteria, which triggers an immune response without the need for eggs. The study, led by John Treanor, showed that the experimental vaccine worked well in people, with about half of participants responding strongly to just one microgram of the vaccine.
A new $2.1 million NIH grant will help MU scientist Dongsheng Duan develop a treatment that prevents heart muscles from weakening due to Duchenne muscular dystrophy. Tests have shown that treating skeletal muscle alone can lead to complications, highlighting the need for comprehensive treatment targeting both skeletal and cardiac muscle.
A Greek trade emporium on Egyptian soil thrived under the protection of powerful Eastern empires. The Greeks who inhabited Naukrtis formed a unique culture despite being from warring city-states, emerging with a national Greek identity. This arrangement enabled the exchange of art and culture between Greece and Egypt.
University of Illinois scientists have discovered a method to reduce the bitterness of ginseng in energy drinks by over half using cyclodextrins. This innovation could improve the health benefits of these beverages and expand their market, particularly in the US energy drink industry.
The newly identified genus Koreaceratops hwaseongensis is the first ceratopsian dinosaur from the Korean peninsula, featuring a parrot-like face and unique fan-shaped tail. It lived approximately 5-6 feet long and weighed around 60-100 pounds, indicating it was relatively small compared to its giant relatives.
Researchers have found a way to improve the reliability of carbon nanotube-based nanoelectromechanical systems by using diamond-like carbon electrodes. This enables reliable switching and storage of binary states in devices, advancing the technology from laboratory-scale demonstrations to practical applications.
A large-scale study found that patients with rheumatoid arthritis have a 60% higher risk of heart attack just one year after diagnosis, with the risk increasing rapidly in the first few years. The study emphasizes the importance of monitoring heart risk from the moment RA is diagnosed.
Researchers suggest scheduling mammograms in the first week of a woman's menstrual cycle to improve accuracy in detecting breast cancer. The study found that mammography conducted at this time was more sensitive, but not necessarily specific, for finding breast cancers in pre-menopausal women.
Researchers found that patients with irritable bowel syndrome (IBS) who chose a positive color on a color chart were nine times more likely to respond to hypnotherapy. The study suggests the use of this test as a predictor for responders.
Researchers have identified a new bacterium that contributes to the deterioration of the RMS Titanic's exterior, accelerating metal corrosion. The novel Halomonas titanicae has been found to adhere to steel surfaces, creating corrosion products.
Researchers argue that the US Fish and Wildlife Service should consider societal values when determining whether species need protection from extinction. A study analyzing public opinions on wolves in the northern Rocky Mountains found mixed results, contradicting the agency's claim that attitudes have improved over time.
Scientists at Rice University have discovered that poly(dA) repeats behave differently when stretched, requiring less force to lengthen without additional effort. The findings raise more questions about the role these repeats play in gene regulation and genome packaging.
A Phase I/II gene therapy trial has demonstrated no evidence of toxicity in four patients with hemophilia B. The trial uses a vector developed at St. Jude Children's Research Hospital and UCL to correct the inherited bleeding disorder.
A study published in The Lancet found that daily low-dose aspirin reduced death rates from a range of common cancers by 21% during trials. Long-term follow-up showed that the risk of cancer death remained 20-60% lower in groups who had previously been allocated aspirin.
A new study found that combining exenatide with insulin provides better blood sugar control in patients with type 2 diabetes, achieving near-normal levels in 60% of participants. Additionally, Byetta recipients lost an average of four pounds during the study, while placebo recipients gained two pounds.
Experts warn that consumers have little control over their online tracking and profiling, leading to a loss of privacy and potential manipulation of behavior. Nancy King, associate professor at Oregon State University, advocates for a balance between protecting consumer privacy and allowing behavioral advertising to thrive.
A new study published in Spine found that patients who received early physical therapy after an episode of low back pain were less likely to receive epidural steroid injections, lumbar surgery, and frequent physician visits. This suggests that prompt access to physical therapy can lead to improved outcomes and reduced healthcare costs.
Researchers at Princeton University discovered a gene, CCDC40, associated with congenital heart defects in humans. The gene controls right-to-left patterning and is also linked to respiratory disorders.
Tim Dixon received the 2010 George P. Woollard Award for his groundbreaking research in space geodesy, which has paved the way for studying earthquake hazard, volcanic processes, and climate change. His work has also contributed to understanding subsidence in Mexico City and the melting of the Greenland ice cap.
Scientists at Einstein College of Medicine discovered that genes involved in building protein complexes are activated randomly, not coordinately. This unexpected finding may change the way scientists think about cellular processes and synchronization.
Researchers found that a massive, uncontrolled activation of the complement system led to severe lung damage and death in young adults. The study's findings suggest that this over-reaction is responsible for making healthy young and middle-aged adults seriously ill during pandemic flu, explaining why they are disproportionately affected.
Studies reveal that stem cell transplantation is safe and effective in treating various hematologic malignancies, with no significant increase in overall cancer risk. Researchers found a promising new treatment to prevent chronic graft-versus-host disease, a serious complication of stem cell transplantation.
Researchers at Emory University School of Medicine have adapted gene chip microarray technology to the study of glycans, using an approach called 'shotgun glycomics.' This technique allows for the separation and analysis of thousands of glycans, enabling researchers to test what sticks to them. The method has been used to identify a mo...
A UNC-led research team developed a searchable database of more than 200 commonly used antibodies to help genetic scientists precisely test DNA. The database addresses the issue of specificity in antibody tests, which can affect gene regulation and human diseases.
Researchers found that individual volunteers' perceptions of optical illusions varied greatly due to differences in brain size. The primary visual cortex area affects the extent to which we see visual illusions.
A new study finds that birth light cycles significantly impact the development of biological clocks in mice, which may explain why people born in winter months are at a higher risk of certain neurological disorders. The experiment reveals that even after weaning, biological clocks remain affected by the initial light cycle.
A new study reveals that climate change is causing northern wildfires to burn more fiercely and release more carbon into the atmosphere than previously thought. The research found that fires in Alaska's interior have become more severe over the past decade, pumping out more greenhouse gases and accelerating permafrost loss.
Researchers have identified a mechanism to regenerate insulating layers in the brain that protect nerve fibers in multiple sclerosis. The study shows activating stem cells can repair injury in the central nervous system, reversing damage caused by MS.
A new study by the University of Utah found that the LouseBuster is highly effective in killing head lice and nits, with 94.8% mortality rate. The device uses warm air to dry out lice and nits, making it a safe and easy treatment option.
New research reveals that the Alps' U-shaped valleys can endure glacial attack and retain their V-shaped notches. Scientists found that glaciers fill the gorges with ice and rock, protecting them from being scoured away. The rivers then return to clear out debris deposited by previous glaciers.
Researchers present promising new treatment options for advanced asymptomatic follicular lymphoma, mantle cell lymphoma, and early Hodgkin disease. The study shows that upfront rituximab therapy can significantly prolong the time until a patient may require chemotherapy.
Researchers have made significant strides in understanding the optimal use of BCR-ABL inhibitors for acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML). A new gene target has also been identified, showing a long-term survival advantage for patients treated with imatinib earlier in the treatment protocol.
A Phase I trial indicates that ponatinib produces significant hematologic and cytogenetic responses in patients with chronic myeloid leukemia (CML) who have developed resistance to standard treatments. The drug showed strong efficacy in patients with the T315I mutation, which is resistant to current therapies.
Researchers investigate genetic predictors of stroke in pediatric sickle cell disease patients, validating biomarkers and identifying new risk factors. Additionally, a potential breakthrough may inhibit malaria transmission, offering hope for controlling the disease.
Researchers focus on disrupting FLVCR protein in mosquitoes to block Plasmodium transmission, a crucial step in preventing malaria spread. By targeting this protein, they hope to develop a vaccine to stimulate an immune response and prevent the disease.
Researchers found that apixaban was more effective than enoxaparin in preventing major venous thromboembolism without increasing bleeding risk. This innovative treatment has improved methods for patients undergoing hip or knee replacement surgery, and may also be beneficial for cancer patients with VTE.
A team of researchers discovered that mutant enzymes in leukemia create a chemical poison to cause cancer. This finding suggests a new avenue for treating acute myelogenous leukemia and other cancers.
Astronomers have made new discoveries about exploding stars, including pauses, flickers, and flares that were not previously observed. Using sensitive data from a satellite, they studied four novae and found three stalls before reaching peak brightness, with all experiencing flickering or flaring during the outburst.
A study using the MEADERS (Medication Error and Adverse Drug Event Reporting System) system found that communication problems and lack of knowledge are leading causes of medication errors, with cardiovascular medications being the most commonly associated. The system has been successful in reducing harm to patients, documenting 11% of ...