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Science News Archive May 2013 - Page 17


Page 17 of 30

Renaissance in new drugs for rare diseases

A combination of factors is fueling a renaissance in drug development for rare diseases. Smaller pharmaceutical companies and patient advocacy groups are playing key roles in bringing new treatments to market. With over 7,000 rare conditions affecting 200,000 patients or fewer, these breakthroughs offer hope for fuller lives.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateMay 15, 2013

Long-term outcomes in patients with advanced coronary artery disease are better than expected

A study published in the European Heart Journal found that long-term outcomes in patients with advanced coronary artery disease are better than expected. The researchers analyzed data from 1,200 consecutive patients with refractory angina and found a low mortality rate of 3.9% at one year and 28.4% at nine years.

SourceMinneapolis Heart Institute Foundation·JournalEuropean Heart Journal·DateMay 15, 2013

Proteome atlas for the tuberculosis pathogen

Researchers have created a comprehensive map of the tuberculosis protein, allowing scientists to pinpoint specific proteins and discover new ones. This resource may aid in the development of new therapies and early detection methods, targeting the main target for medication: pathogen proteins.

SourceETH Zurich·JournalCell Host & Microbe·DateMay 15, 2013

JCI early table of contents for May 15, 2013

Two studies published in the Journal of Clinical Investigation found that chemokine stimulation is not required for T cell migration to transplanted organs. Instead, immune-stimulating proteins expressed by the organ direct T cells to migrate. Additionally, researchers identified a protein called TRAIL that causes cell death and can be...

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMay 15, 2013

A better way to prevent child abuse

A UK study found that the £10 million Family Nurse Partnership program can only tackle around 10% of families involved in child maltreatment. Researchers suggest using different risk factors to identify vulnerable children could reach three times more abusive families.

SourceUniversity of Nottingham·JournalJournal of Public Health·DateMay 14, 2013

Dual chamber ICDs show higher risk of complications

A recent study published in JAMA Network found that dual-chamber implantable cardioverter-defibrillators (ICDs) are associated with a higher risk of device-related complications compared to single-chamber ICDs. The study analyzed over 32,000 patients and discovered that rates of complications were lower for single-chamber devices.

SourceJAMA Network·JournalJAMA·DateMay 14, 2013