A study led by Purdue University found that medication therapy management by phone reduced hospitalizations by 86% in low-risk Medicare patients, who were three times less likely to be hospitalized. However, the intervention had no significant impact on higher-risk patients, highlighting the need for tailored strategies.
Tropical Cyclone Ita intensified with a large eye feature and sustained winds of 65 knots/75 mph. Rainfall analysis revealed rain falling at over 99 mm/h within its feeder bands.
A new technique predicts MRSA toxicity from its genome sequence, allowing clinicians to personalize treatment for individual infections. The study identified 125 genetic mutations associated with high or low toxicity, enabling the prediction of severe disease.
Researchers have found metallopolymers that can evade MRSA's defensive enzymes and destroy its protective walls, causing the bacteria to burst. The metallopolymers mostly left red blood cells alone, suggesting minimal side effects.
A study of 40 black boys aged 9 found that those from disadvantaged environments had shorter telomeres, a biomarker for aging, than their advantaged peers. Boys with genetic sensitivities to stress also showed accelerated telomere shortening.
Researchers at UC Irvine's Sue & Bill Gross Stem Cell Research Center found that bone marrow stem cells significantly improved multiple outcome measures in animal studies of stroke. The effects were robust regardless of dosage, timing, or method of administration.
Saint Louis University researcher Jeffrey Scherrer is investigating the link between chronic opioid use and depression risk. He will analyze medical records of 1 million patients, including those with VA and private sector prescriptions, to understand the impact of opioid exposure on mental health.
Researchers at Vienna University of Technology have discovered that tiny step edges on titanium oxide surfaces enable the accumulation of electrons, allowing oxygen atoms to attach more strongly. This finding offers opportunities for creating more efficient solar cells and catalysts.
A large study found that periodontal disorders such as tooth loss and gingivitis are associated with numerous cardiovascular risk factors. Patients with more teeth had lower levels of CVD risk factors, including diabetes and smoking.
A new approach to estimate seabird populations uses sound recordings to monitor colony size. Researchers set up recorders on remote islands in the North Atlantic and developed an algorithm to automatically count seabird calls, resulting in a more accurate population estimate.
Researchers at Scripps Research Institute receive $472,500 grant to study impact of pain medication exposure in womb on developing brain. The two-year study will use rodent models to understand how subtle changes in brain wiring might lead to later changes in behavior.
Researchers attach DNA-coated building blocks to form structures, but simulations predicted defects. They found hydrodynamic effects play a critical role in the structures' formation, making some patterns more likely than others. This discovery improves our understanding of particle assemblies and has implications for various systems.
Scientists have developed a device that can process whole blood and isolate genetic material for two potential biomarkers within minutes. This rapid detection method could help determine the course of proper treatment, potentially saving lives.
Scientists observe quantum critical point in TiSe2, challenging prevailing theory on superconductivity emergence. Domain wall formation connected to superconductivity, not CDW melting, reveals new phase boundary with implications for understanding superconducting behavior.
China is leveraging strategic investments in research and development and cross-border collaboration to establish a stronger domestic innovation system. The country's returnee scientists and engineers are playing a catalytic role in improving its research and development infrastructure.
A rat model of heroin relapse showed improved brain structure and increased neurotrophic factor expression after acupuncture treatment. The study suggests that acupuncture at specific points may protect brain neurons against injury and promote recovery from heroin addiction.
Computer simulations suggest that co-locating crops with solar panels could reduce water usage for solar farms in sunny, arid regions. Agave plants, which thrive at high temperatures and poor soil, are being considered as ideal crops for this approach.
Researchers identified a protein, nicotinamide N-methyltransferase (NNMT), that can be altered to increase energy expenditures. Reducing NNMT levels in fat and liver cells dramatically reduces obesity and diabetes development in mice.
A study found that anglers and canoeists are key pathways for invasive species introduction into UK waterways. The research highlights the importance of 'Check, Clean, Dry' practices to prevent further spread. By following these simple steps, water users can help protect native ecosystems.
UCSB physicist Tarun Grover has provided mathematical evidence for supersymmetry in a topological superconductor. The research, conducted with colleagues Donna Sheng and Ashvin Vishwanath, appears in the journal Science. Supersymmetry describes a unique relationship between particles, with fermions having boson superpartners.
Parasitic butterfly larvae may use acoustic signals to infiltrate ant colonies, according to a study published in PLOS ONE. The larvae's sound patterns were found to be more similar to those of the queen ant than worker ants, suggesting a potential strategy for infiltration and exploitation.
A clinical trial by UC researchers found that consuming chips with olestra reduces serum polychlorinated biphenyls (PCBs) levels in people exposed to PCBs. Olestra's effect on PCB removal is attributed to solubilizing fat-soluble compounds in the intestine, reducing absorption of these compounds into the body.
Scientists at the University of Bristol have received funding to test a powerful new drug, NLX-101, which selectively targets serotonin receptors in the brain. The goal is to alleviate the distressing breathing abnormality associated with Rett syndrome, a condition affecting 1 in 10,000 female births worldwide.
A worldwide review of studies on animal interventions in healthcare settings for children found a major gap in scientific knowledge. Despite theories emerging since the 1960s, research has been limited, leaving many questions unanswered.
Researchers at the University of Washington have developed an automated approach to aging babies to adults using variable lighting, expressions and poses. The technique works remarkably well, even with unrestrained conditions, and is comparable to manually created renderings.
A new study using the U.S. Senate Chamber as its laboratory found that co-sponsorship of bills is more likely to come from those sitting near each other, highlighting the importance of location in deal-making. The study's findings also showed that more senior senators rely on personal connections rather than their location for support.
Researchers argue that current climate models fail to accurately capture the economic costs of climate change, leading to underestimated damage and ineffective policy decisions. To improve this, scientists must collaborate and update their models more frequently.
Researchers have identified the basal ganglia as a key brain region involved in vocal learning and variability across species. By studying songbirds, they found that this area is responsible for generating variability to aid in learning and performance.
A new study published in SAGE Open found that Southern death-row offenders are more likely to apologize for their crimes, with two times the frequency of non-Southerners. However, the degree of remorse shown by Southerners and non-Southerners did not differ.
Researchers found that small financial incentives increased completion of hepatitis B vaccination among injecting drug users, with 45-49% completing the course compared to 9%. The study suggests offering financial incentives can be achieved in routine clinical practice and improve public health outcomes.
Researchers found strong associations between liking, owning, and identifying music containing alcohol branding and early problematic alcohol outcomes. The study suggests policy or educational interventions to reduce the impact of these exposures.
UT Southwestern researchers found that blocking critical DNA repair mechanisms can slow down tumor growth and increase survival in glioblastoma patients. The study used a drug called NVP-BEZ235, which combined with radiation therapy significantly delayed tumor growth in mice, up to 60 days.
A large population study found that current and recent use of painkillers/anti-inflammatories is linked to a heightened risk of atrial fibrillation among older adults. Over half of the study participants developed atrial fibrillation during the monitoring period, with those currently taking NSAIDs facing an 84% greater risk.
A new study by MIT researchers reveals that coughs and sneezes create a multiphase turbulent buoyant cloud that extends the range of infectious droplets. Smaller droplets can travel up to 200 times farther than previously estimated, while larger droplets fall out, allowing smaller drops to be resuspended by gas clouds.
A total lunar eclipse will be visible in North America on April 15, offering a unique viewing opportunity. The spacecraft's batteries need sunlight to charge, and it will have to pass through the complete shadow twice before the eclipse ends.
A new study finds that adult patients with diabetes who trust their medical provider and feel included in treatment decisions are more likely to take and maintain a newly prescribed antidepressant medication. Shared decision-making is also associated with better adherence later in the course of antidepressant treatment.
A new epidemiology model developed by Brown University researcher Yen-Tsung Huang integrates genomic data from SNPs, gene expression, and methylation to find significant associations with diseases like asthma and brain cancer. The model improves performance and validity across different subjects, paving the way for further applications.
A groundbreaking study has enabled four paraplegic men to regain voluntary movement in their legs through epidural electrical stimulation of the spinal cord. The therapy, which mimics brain signals to initiate movement, demonstrates the potential for functional recovery even years after severe spinal cord injuries.
Researchers identified correlations between protein expression levels and improved survival rates in HPV-negative head-and-neck cancer patients. Survivin expression may serve as a marker for better patient outcomes, particularly those treated with surgery plus radiation.
A new WHO report shows that large, graphic health warnings on tobacco packets in China would significantly increase awareness about the harms of smoking, help reduce smoking rates, and ultimately save lives. The report recommends improving current text-only Chinese health warnings by adding images of tobacco-related diseases.
The Brain Health Registry aims to create a ready pool of research subjects for studies on neurological diseases, reducing costs and increasing efficiency. Volunteers will provide personal history and take online neuropsychological tests, helping scientists analyze brain functions over time.
Scientists at Helmholtz-Zentrum Dresden-Rossendorf develop sophisticated measuring sensors to improve biological treatment stages. The sensors help determine the dynamic of flow and inform treatment plants on optimal mixing strength.
Researchers inhibit heat shock protein 90, shutting off proteases that help ovarian cancer cells escape and spread. In mouse studies, ganetespib treatment reduced metastases, indicating potential therapeutic target for ovarian cancer.
Researchers at UNC School of Medicine have identified a specific RSV-encoded non-structural protein (NS2) as the genetic trigger for severe lung infections in infants. The discovery could lead to new diagnostic tools and treatments, reducing hospitalizations caused by RSV infection.
A team of researchers has demonstrated the advantages of the HOPE fixation strategy, which preserves tissue structure while allowing modern analysis techniques like proteomics and phospho-proteomics. This breakthrough enables personalized medicine and opens up new opportunities for disease research and therapy.
Residents of poorer Chicago neighborhoods face more life-changing negative events and experience a range of serious health issues due to the complex interplay between traumatic events and lack of resources. The study's findings highlight the need for addressing poverty and providing support for vulnerable populations.
Global health funding reached an all-time high of $31.3 billion in 2013, driven by increased support for maternal and child health. Non-communicable diseases (NCDs) continue to receive relatively little development assistance, despite being a major burden in the developing world.
The study found that rural households in areas with low access to improved water and sanitation are more likely to lack these basic services. Geographical mapping reveals substantial levels of inequality in access to improved drinking-water supplies and sanitation across sub-Saharan Africa.
Adding an impurity to a two-dimensional lattice structure can create defects that settle into harmony, restoring order and creating a 'screen' to protect the rest of the material. This finding could lead to new ways of engineering materials with unique properties.
Researchers found that infants as young as a few months old can distinguish between word-like and non-word-like sounds, indicating a fundamental knowledge of language. This discovery challenges the traditional view that language is shaped by environment and experience.
Researchers at Penn State College of Medicine found that breast cancer cell subpopulation cooperation can lead to increased tumor growth. The study discovered that two distinct subclones within mammary tumors relied on each other to expand, with one producing a protein called Wnt1 that promoted tumor growth.
Researchers at Rice University have designed a sophisticated synthetic genetic circuit that signals increases in the degradation of proteins by the cell's ubiquitin proteasome system (UPS). The Deg-On circuit produces a green fluorescent signal linked to UPS degradation, allowing researchers to monitor proteasomal activity.
Scientists at the University of Washington are developing new methods to rapidly identify and treat emerging infectious diseases. The researchers aim to create a flexible arsenal against multiple pathogens, using machine-learning computer modeling and genomic analysis to discover ways to measure disease severity.
Researchers at Rice University and Nanyang Technological University have developed a scalable CVD process for producing one-atom-thick layers of 2D molybdenum diselenide, a highly sought semiconductor. The new method offers improved electronic properties compared to similar materials like graphene.
Researchers at the University of Adelaide found that a common diabetes treatment, GLP-1 in combination with insulin, can slow down stomach emptying after eating, leading to extended periods of hypoglycemia. This may result in increased health risks for people with type 2 diabetes.
The innovative Healthy Aging Brain Center care model improves health outcomes and quality of care for older adults with cognitive impairment by reducing patients' behavioral and psychological symptoms. The model generates an annual net cost savings of up to $2,856 per patient, with potential nationwide cost savings of billions of dollars.
Researchers at the University of Southampton found that a combination of cetuximab and chemotherapy was not effective in treating advanced bowel cancer that had spread to the liver. The study, published in The Lancet Oncology, suggests that this treatment approach may even accelerate cancer progression in some cases.
A group of scientists is calling for better recognition of local experts' role in conservation biology. Local guides play a critical part in data collection and are essential to successful conservation efforts.
As the US population ages, Alzheimer's disease is projected to increase from 3 million in 2011 to over 10 million by 2050, affecting broad-based national policies. The annual cost of care for people over 70 is estimated at $157-$215 billion, with costs expected to reach $1.2-$1.6 trillion by 2040.
Researchers analyzed genomic data from The Cancer Genome Atlas and identified three molecular clusters in lower-grade brain tumors. Tumors with IDH1/IDH2 mutations and co-deletion of chromosome arms 1p and 19q have a median survival of around eight years, while those without these mutations have a median survival of only 18 months.