The ClinEpiDB database has released new data from the MAL-ED study, which investigated environmental exposures early in childhood and their impact on growth and development. The dataset contains over 1.3 million observations covering anthropometrics, nutrition, vaccination status, and more.
Researchers discovered that sex-determining genes control beetle horns and identified the timing of sex differences appearing at 36 hours after a reference point. The study found that transforming gene suppression during larval stages leads to male-like horn formation in females.
New research finds differences in breast milk composition between normal weight and overweight mothers, with specific metabolites identified as risk factors for childhood obesity. The study suggests that a tailored mix of nutrients in breast milk could be therapeutic targets to protect children from obesity.
Research in mice and rats reveals a molecular pathway stimulated by physical activity that promotes nerve regeneration after spinal cord injury. A key molecule called CREB-Binding Protein (CBP) is identified as a therapeutic target to increase regeneration, with promising results in animal models.
Researchers at KAUST developed a new sensor using fluorinated metal-organic frameworks (MOFs) that can detect critical gas parameters for human comfort and safety. The MOFs can selectively remove sulfur dioxide from flue gas with high affinity, making them suitable for carbon capture and storage applications.
A genetic study of an outbreak of Enterococcus faecalis revealed how the organism became resistant to new antibiotics and adapted to infect human blood. The research identified multiple mutations that enabled the bacteria to resist host immune systems and antibiotics.
Researchers visualize HIV's shape and vulnerabilities using single-molecule Förster resonance energy transfer (smFRET) technology. The study provides a direct means of seeing the dynamic machine-like structure of the HIV envelope, which can be targeted by antibodies to eliminate infected cells.
The Charisma for Youth program has shown strong results in improving social skills in children with autism, ADHD, and self-worth challenges. The program involves virtual sessions that teach real-world social scenarios, resulting in improved ability to understand others' points of view, start conversations, recognize emotions, and build...
A study by UCSF researchers found that nearly one in seven kidney donors experience potentially adverse events related to their donation. Long-term systematic renal monitoring and routine checkups for living kidney donors are recommended to prevent renal failure and cardiovascular issues.
A new study has found that women with low-density lipoprotein (LDL) cholesterol levels below 70 mg/dL may be at a higher risk of hemorrhagic stroke. The study also found that women with the lowest triglyceride levels had an increased risk of bleeding strokes compared to those with the highest triglyceride levels.
A new study from Stanford University suggests a way to map precisely where and how to use groundwater recharge to refill aquifers and stop sinking in California's Central Valley. The model, based on remote sensing data, indicates areas of high subsidence risk and optimal recharge locations.
Researchers analyzed firearm-injured patients arriving at Philadelphia-area hospitals within 15 minutes of each other, revealing 54 cluster events over 11 years. These clusters were more likely to occur at night and be female, with lower mortality rates than traditional mass shootings.
Researchers developed an Al anode design with Cu codeposition, improving cycling stability and capacity retention. The new battery configuration achieved a capacity retention of ~88% over 200 cycles with a high areal density cathode.
Researchers at CNIC have discovered that the protein p38gamma plays an essential role in initiating cell division in liver cells, making it a promising therapeutic target for liver cancer. The study found that inhibiting p38gamma slows down the development of liver cancer in mice, suggesting potential treatment options.
The Event Horizon Telescope project has captured the first-ever image of a black hole, located at the heart of galaxy Messier 87. The image reveals a ring-like structure with a dark central region, confirming our understanding of general relativity.
Climate scientists are partnering with the City and County of San Francisco to assess how climate change may influence the intensity of atmospheric rivers and associated precipitation. Using high-resolution climate simulations at a resolution of 3 km, researchers aim to provide more accurate predictions about extreme weather events in ...
The Event Horizon Telescope (EHT) has captured the first direct visual evidence of a supermassive black hole, located 55 million light-years from Earth. The image reveals the black hole's mass is 6.5-billion times that of the Sun.
A study from U of T Mississauga uses new techniques to reconstruct summer temperatures over the last 13,600 years, confirming current global warming trends. The research reveals that recent climate warming in the central Yukon region has surpassed the warmest temperatures experienced in the previous 13,600 years.
A UBC study found that a high-fat, low-carb breakfast can prevent large blood sugar spikes and improve glycemic control. Participants with well-controlled Type 2 Diabetes experienced reduced glucose exposure and improved stability of glucose readings after consuming a low-carb breakfast.
A new research project aims to investigate how opioid use is treated in adolescence, a significant public health problem. The study will analyze insurance claims data to identify patterns of opioid use leading up to addiction and long-term treatment outcomes.
A new molecule, EPB-53, has been discovered to increase FGF21 levels in the liver and plasma through oral administration. This could lead to new therapeutic strategies for treating type 2 diabetes and non-alcoholic fatty liver disease.
Researchers have uncovered the remains of a new species of human, Homo luzonensis, in the Philippines. The fossil discovery provides significant insights into human evolution across Southeast Asia, with unique skeletal features compared to other known hominin species.
Researchers at the University of Saskatchewan found that even tiny amounts of neonicotinoid pesticides can severely impact flying insects' motion detection abilities. The study's results suggest that very low doses of these widely-used neurotoxins can profoundly affect a flying insect's ability to detect movement, making it crucial for...
Researchers at Johns Hopkins Medicine have found that AXT107 stops abnormal blood vessels in the eye from leaking vision-blocking fluids. The compound strengthens connections between cells, creating a watertight barrier and preventing fluid permeation into surrounding tissue.
Researchers analyzed genetic information from 7,026 UK children to find polygenic scores that predict up to 11% of the difference in intelligence and 16% of the difference in educational achievement. The study used multivariate genomic approaches to increase predictive power and found improved accuracy when analyzing multiple traits.
Scientists found that disrupted autophagy leads to protein accumulation, causing neuronal communication problems and behavioral changes resembling human autism spectrum disorder (ASD) and schizophrenia. The study confirms a link between mTOR-autophagy and GABA signaling in the development of social behavior deficits.
Scientists at UCL have successfully produced individual 2D phosphorene nanoribbons with unique properties, opening up new avenues for applications in batteries, solar cells, thermoelectric devices, and more. The ribbons' flexibility and scalability make them promising for transforming industries.
A recent UFZ study analyzed 10,000 studies on yield and biodiversity in intensification measures, finding a 20% increase in yield but a 9% species loss. Medium-intensity areas showed the highest increase in yield and greatest species loss.
Researchers analyzed data from Fresno and Bakersfield before, during, and after the California drought to understand its impact on ozone air quality. They found that severe drought conditions led to a 20% decrease in ozone production due to reduced isoprene concentrations and altered VOCs.
Researchers at the University of Southampton found that Cognitive Behavioural Therapy (CBT) tailored specifically for IBS is more effective in relieving symptoms than current standard care. CBT sessions delivered over the telephone or through an interactive website improved patients' quality of life and reduced symptoms after 12 months.
Cherokee inscriptions found in Manitou Cave reveal evidence of secluded ceremonial activities, including stickball and ritual events. The inscriptions provide a direct link to how some Native Americans viewed caves as sacred places.
Researchers used satellite radar data to map the extent of standing water and measure land subsidence in the Houston-Galveston area, revealing large flooded areas fell outside FEMA designated flood zones. The study highlights the need for revising flood hazard zone maps and resilience plans in coastal regions.
Researchers found rates of heat-related illnesses reduced by half in states with mandated guidelines, highlighting the effectiveness of safety policies. The study provides compelling evidence that exertional heat illness can be prevented through mandated safety measures.
Two studies presented at The International Liver Congress highlight the increasing burden of non-alcoholic fatty liver disease (NAFLD) in people with HIV infection, leading to a risk of progressive liver disease. NAFLD prevalence is higher in HIV-infected individuals than the general population.
A team of archaeologists has discovered the first example of Palaeolithic figurative cave art in the Balkan Peninsula, estimated to be around 34,000 years old. The site, Romualdova Pe?ina in Croatia, features paintings of a bison, ibex and possible anthropomorphic figures.
Scientists at the University of New Hampshire have documented a unique event called fast negative breakdown, which shows that lightning can form in clouds through an upward pathway. This discovery provides new insight into how lightning begins and spreads, and may lead to a better understanding of this natural phenomenon.
Researchers at Lund University developed a new approach to treating bacterial meningitis by cutting up neutrophil extracellular traps (NETs) with DNase, exposing bacteria to the immune system and antibiotics. This method has shown promise in reducing bacterial loads without antibiotic intervention.
The PATHS program, funded by Chan Zuckerberg Initiative grants, aims to empower underrepresented students to succeed in STEM fields at UC San Diego. The initiative replicates successful models from UMBC's Meyerhoff Scholars Program and offers research experiences, team learning, peer counseling, and more.
Researchers have developed a self-healing catalyst, SION-X, that can efficiently release hydrogen from ammonia borane, a promising energy carrier. The catalyst is based on abundant mineral Jacquesdietrichite and can be easily regenerated, stored, and handled, making it suitable for large-scale applications.
Researchers synthesized new In0.28Ga0.72Sb nanowires with high carrier mobility and fast IR response, outperforming existing materials in terms of responsivity and decay times. The minimized crystal defects are attributed to a catalyst epitaxy technology that enables precise atom alignment.
Researchers from NYU Meyers College of Nursing used FDNY GIS maps to develop an educational program for nurse practitioners, which improved their care and interventions on the opioid crisis. The study found that local, real-time maps informed clinical practice and increased screenings for risk-taking behaviors in adolescent populations.
The Human Genetics Scholars Initiative aims to increase workforce diversity in human genetics research by providing intensive mentoring, skill-building, and community-building opportunities. The program will support up to 240 diverse young researchers over five years.
A recent study published in The Gerontologist suggests that the link between caregiving and negative health effects has been overstated. After analyzing data from over three decades of research, Johns Hopkins researchers found a weak association between caregiving and immune system biomarkers.
A study of 1,700 physician mothers found that those in procedural specialties who take on more household tasks report higher career dissatisfaction. The authors suggest more equitable distribution of tasks or outsourcing duties may help sustain physician moms.
UTSA joins NASA's Resilient ExtraTerrestrial Habitats institute (RETHi) to advance space smart habitat designs for deep space habitats, leveraging expertise in civil infrastructure with advanced technology fields.
Scientists have captured the first-ever image of a black hole, which reveals the massive black hole at the center of the galaxy Messier 87. The image was achieved using the Event Horizon Telescope (EHT), an unprecedented Earth-sized virtual telescope linking telescopes around the globe.
A new study found that reducing meat consumption could cut greenhouse gas emissions by the most, while also increasing use of animal byproducts. By combining various strategies such as eliminating waste and finding uses for byproducts, researchers estimate a 43% reduction in emissions from the meat supply chain.
The article review found no risks associated with breastfeeding mothers receiving routine and standard vaccinations. In fact, there are benefits for both mothers and infants, including enhanced antibody response and reduced vaccine-related fever after infant vaccination.
A large cohort study in northern England found significant clustering of primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis in specific regions. The researchers suggest that exposure to a persistent environmental agent may play a key role in the development of these autoimmune liver diseases.
A recent study by ETH researchers suggests that anthropogenic climate change is causing simultaneous heatwaves across the Northern Hemisphere, affecting key agricultural regions and densely populated areas. The study found that such large-scale heatwaves first appeared in 2010 and have since become more frequent and widespread.
A diet high in animal protein and meat is associated with a greater risk of death, according to a 20-year follow-up study. Men who primarily consumed animal-based proteins had a 23% higher risk of mortality compared to those with a balanced ratio of animal and plant-based proteins.
Cancer cells dependent on WRN enzyme to survive due to DNA repair system loss; MSI signature identified as effective biomarker for vulnerable tumors.
Researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types, discovering thousands of key genes essential for cancer's survival. The team developed a system to prioritize and rank 600 drug targets promising for development into targeted cancer treatments.
A recent study found that kidney disease can trigger cognitive impairment even in its early stages, affecting approximately one in two patients. The cognitive decline is not age-related and worsens with declining kidney function.
Research reveals how p53 influences X chromosome inactivation, a critical process for healthy brain and spinal cord formation. This discovery explains why females are more likely than males to be born with neural tube birth defects.
The Science of Chocolate project uses storytelling to promote interest in scientific careers, particularly among girls, by highlighting the work of women researchers. The project has received funding from the Spanish Foundation for Science and Technology and is published in Catalan and Spanish.
Researchers at the Wellcome Sanger Institute have sequenced the genome of a non-toxigenic strain of Vibrio cholerae from WWI, showing it is distantly related to strains causing modern pandemics. The strain lacked a flagellum and possessed genes for ampicillin resistance.
NASA has launched the AZURE mission, carrying instruments to measure atmospheric density and temperature in auroral regions. The mission will release colorful gas tracers to track particle flow and provide valuable data on ionosphere dynamics.
A Belgian team developed a new bioinformatics method called cisTopic to analyze gene regulation in cells. The method discovers common topics of gene control across cells, revealing unique gene activity patterns. This enables researchers to understand cellular diversity and its implications for diseases.
The £1.1 million project aims to develop bioresorbable stents that prevent complications associated with metal stents, treating severe peripheral vascular disease. The new device will dissolve between 18-24 months, preventing life-long presence of metal stents and associated chronic inflammation.