A multi-center study assesses medicinal mushrooms and Chinese herbs for therapeutic benefit in treating acute COVID-19 infection. The MACH-19 trial evaluates the safety and feasibility of two investigational compounds, one in capsule form and another as a Chinese herbal formula.
Studies using virtual reality environments revealed that individuals with anxiety disorders exhibited increased brain activity in response to perceived threats, even in safe areas. The findings highlight the need for personalized treatments that help patients regain control over their body.
Researchers predict that targeted transport measures in Cairo will reduce health-damaging pollutants by up to 55% and global warming emissions by an average of 12.4%. Better vehicle inspection and maintenance, as well as improved public transport infrastructure, are key strategies identified in the study.
Researchers from the University of Rochester have further evidence that genes are evolving defensive mechanisms to counteract harmful genetic elements. The study found that specific genes developed weapons-like structures to combat 'parasites' in the human genome, highlighting the ongoing 'arms race' between these two forces.
Researchers used DNA analysis to confirm traditional Tsleil-Waututh Nation fishing practices that promoted sustainable management and conservation. These practices, which selectively harvested male salmon, allowed for larger harvests while maintaining healthy populations and successful spawning.
Research at Uppsala University found a correlation between specific genes and prognosis in Chinese patients with cardia cancer. Focal amplification of the ERBB2 gene was linked to better prognosis, while EGFR amplification had worse outcomes.
A study published in Cardiovascular Research found that an anticoagulant medication can improve the survival of COVID-19 patients and shorten the duration of active SARS-CoV-2 infection. The medication, low-molecular-weight heparin, also curtails viral persistence by inhibiting the virus's ability to bind to cells.
Researchers have used advanced microscopy to study the ultrastructure of huntingtin inclusions, revealing different mechanisms of aggregation that lead to distinct biochemical properties. The findings suggest targeting inclusion growth as a potential therapeutic strategy for slowing Huntington's disease progression.
Researchers at Virginia Tech uncover two types of microorganisms that produce amorphous carbon, a form of elemental carbon thought to be formed under extreme conditions. This discovery challenges existing knowledge and raises questions about its impact on the Earth's carbon cycle.
A new study in India reveals that more than half of surveyed crop varieties are under threat of extinction, with 50% considered threatened across five different agroecological regions. The Varietal Threat Index methodology proposes a systematic way to monitor changes in varietal diversity on farms.
Researchers at Ruhr-University Bochum study coral reefs' reaction to climate change, discovering polyp bailout as a potential survival mechanism. The study reveals different species react with varying intensity to environmental stressors, and that individual polyps can survive and grow in new locations.
Researchers have developed a new synthetic molecule that recruits immune cells to fight cancer. The treatment shows promising results in mouse models of breast and pancreatic cancer, with some animals cured after just a few injections.
Abnormalities in brain cells and axons may lead to increased blood flow and more severe symptoms of autism. The study provides insights into the biology of autism spectrum disorder and potential therapeutic targets.
A recent study by Sanford Burnham Prebys and the National Cancer Institute has shown that CRISPR-Cas9 gene editing can favor cells with mutated forms of genes linked to cancer. This highlights the importance of monitoring patients undergoing CRISPR-based gene therapy for cancer-related mutations.
Scientists confirm existence of sigma-hole, a phenomenon previously predicted but never directly observed. This breakthrough enables understanding of interactions between individual atoms or molecules, facilitating refinement of material and structural properties.
The study identifies two central processes shaping brand flagship platforms: consumer crowdsourcing and crowdsending. Brands can tailor the degree of consumer involvement, leading to four different states of consumer-platform relationships. The platformization of brands requires fundamental changes to established notions.
A new study shows that specially designed scaffolds can improve the repair of spinal cord injuries in mice by promoting axon regrowth and angiogenesis. The scaffolds, made from supramolecular polymers, also enhance neuronal cell survival and functional recovery.
The University of Kentucky's Sanders-Brown Center on Aging has received a five-year grant renewal to discover and validate biomarkers for vascular cognitive impairment and dementia. The program, which aims to develop a toolbox of biomarkers, will increase to 200 participants and focus on inclusivity and diversity.
A Kaiser Permanente study of over 20,000 participants found that people who exercised regularly and spent time outdoors during the pandemic reported lower levels of anxiety and depression. The study suggests that public health officials should encourage outdoor physical activity to maintain mental health during emergencies.
Researchers found that when mothers and children are coordinated at the behavioral level, their physiological activity follows the mother's. The study highlights the importance of tuning in to a child's cues and being responsive to their behaviors during playtime.
The PERSEPHONe project aims to create a novel technological platform for photonics based on metal-halide perovskites. Early stage researchers will be trained in materials design, device development and adaptability.
Rice scientists developed a comprehensive approach to building better base editors, molecular machines that target and fix faulty DNA at single-base resolution. Their new strategy combines theory and experimentation to pinpoint binding energies and characterize deaminase interactions with ssDNA.
Researchers from Germany, China, Israel and Vietnam cracked the code on attosecond collision dynamics in solids. By analyzing high harmonic generation (HHG) in solids, they unveiled the structure and dynamics of information encoded within the band structure.
Scientists at Tokyo Institute of Technology developed a new peptide sensor to detect and quantify water-soluble synthetic polymers in wastewater. The technique uses machine learning algorithm to identify and discriminate between different polymers.
A team of researchers found that microbes are responsible for the formation and production of methane in coal deposits. They analyzed methoxyl groups in coal samples from around the world and used stable isotopes to show that organic material becomes coal through microbial action, contradicting traditional geochemical understanding.
New research reveals that sinking tectonic plates are significantly weakened as they enter the mantle, but not broken apart entirely. The study's computer model shows a 'tectonic snake' shape, with stresses pinching the plate along weak points.
A new study suggests that UK plant-based alternative food consumption has nearly doubled over the past decade, with younger generations and women being more likely to adopt this diet. The research found that plant-based milks were the most popular among the UK population, followed by vegan sausages and vegetable burgers.
Researchers found a repeated link between volcanic eruptions and dynastic collapse in China's Imperial Era, with 62 of 68 collapses preceded by at least one eruption. The study highlights the need to prepare for future eruptions and emphasizes the importance of building resilient societies.
Researchers at Flinders University have developed a virtual individual patient model to predict the success of dental appliances in treating sleep apnea. The new approach uses standard testing and clinical data to create a machine learning-based model that predicts treatment outcome in about 60-100% of cases.
A team at the University of Córdoba has created a method to utilize lignin, a plant-derived substance, in drug synthesis processes for cancer treatments. The resulting 2.6-Dimethoxyquinone compound is highly valuable and can be used as a starting reagent.
The £3.6 million equipment will enable researchers to measure trace levels of radioactive elements, particularly actinides, in samples from UK nuclear facilities and natural environments.
A 13-year study tracked 21,000 young drivers and found that those who took part in a resilience program were 24% less likely to have any crashes and 42% less likely to crash at night. The program addressed common youth risks like alcohol and drugs, promoting a culture of safety.
A genetic comparison of nearly two-thirds of the known species of rockfish pinpoints genes linked to their varying lifespans, which range from less than a decade to over 200 years. The study highlights trade-offs of long lifespan, including smaller populations and adaptations that increase survival
A major Finnish–Norwegian study found that obesity does not lower the risk of subarachnoid haemorrhage, as smoking habits are a significant factor in the condition. The study analyzed over 200,000 individuals and comprehensively considered confounding factors.
Researchers found that exposure to common loud sounds causes fluid buildup in the inner ear, leading to hearing difficulty. Treating this buildup with hypertonic saline may help prevent or reverse nerve damage and save hearing.
Researchers developed an injectable therapy that uses bioactive signals to trigger cells to repair and regenerate damaged spinal cords. The therapy, which mimics the extracellular matrix of the spinal cord, has been shown to regenerate axons, reduce scar tissue, and improve motor neuron survival.
Researchers found a significant male bias in surgeon referrals, with male physicians more likely to refer patients to male surgeons. Female physicians were only 1.6% likelier to refer patients to a female surgeon, further widening the gender pay gap in medicine.
A Cleveland Clinic study shows that bariatric surgery significantly lowers the risk of progression to cirrhosis, liver cancer, or liver-related death. Bariatric surgery also reduces the risk of developing serious cardiovascular diseases such as heart attack and stroke.
The BBV152 COVID-19 vaccine demonstrated robust antibody response and induced 77.8% protection against symptomatic COVID-19 in a phase 3 trial. No severe vaccine-related adverse events or deaths were reported among participants.
A Cornell University study finds that rural Bangladeshi villagers rely on local experts, spiritual views and social justice to evaluate new coronavirus information. They use a five-part system called 'situated fact-checking' to assess claims, considering factors like the source's reputation and the community's sense of morality.
A team of Canadian researchers has successfully simulated baryons on a quantum computer, marking an important step towards more complex simulations. This breakthrough enables scientists to study neutron stars, the earliest moments of the universe, and the revolutionary potential of quantum computers.
A study of 35 low- and middle-income countries found that less than one-third of individuals with high cholesterol received treatment. This highlights the inadequate care for hypercholesterolemia in these regions, a major risk factor for cardiovascular disease.
A study of nationally representative survey data found that U.S. adults 50 and older with visual impairment are at higher risk for substance use or disorders compared to those without visual impairment. The analysis highlights the need for increased attention to substance use prevention and treatment among this vulnerable population.
Research analyzed keywords in pre-Qin Confucian and Legalist classics to compare motivational tendencies. The study found that Legalists used power and reward more frequently than Confucians, who were also driven by power but less so by rewards.
A large national survey found that positive and encouraging strategies are more effective in helping adults with severe food aversions than forceful approaches. Researchers recommend using structure around eating, providing safe foods, and teaching cultural or nutritional lessons to improve attitudes towards food.
Researchers investigated the impact of mRNA vaccines on dialysis patients' immunity against Sars-Cov-2 variants. They found that while many produce reactive T cells, protective antibodies are formed less frequently. This immunological memory can be strengthened through vaccination and repeated contact with the pathogen.
A new species, Brighstoneus simmondsi, with a distinctive bulbous nose has been identified by University of Portsmouth and Natural History Museum scientists. The discovery was made through meticulous analysis of Iguanodon bones found on the Isle of Wight, which revealed subtle differences indicating a new species.
A study published in Environmental Research Letters found that bioenergy crops increase biodiversity by 75% compared to traditional agricultural crops, with benefits for birds, insects, plants, and soil biodiversity.
A literature review analyzing COVID-19's impact across cultural groups reveals significant differences in mortality, transmission, and government mandates. The study highlights the importance of empathy and understanding cultural context to improve science communication.
A new liquid biopsy method developed by researchers at Pohang University of Science & Technology (POSTECH) demonstrates high sensitivity and specificity in detecting tumor DNA in the blood. The technique can detect even one to three specific tumor DNAs, offering a promising approach for early cancer diagnosis.
A recent study found that using mechanical tools can improve understanding of complex sentences and vice versa. Researchers discovered that motor training with tools activates the same brain region as syntax exercises, suggesting that these skills rely on shared neurological resources.
Since the National Cancer Act of 1971, cancer death rates in the United States have decreased by nearly three quarters, according to a recent study published in JAMA Oncology. The study found that progress against cancer deaths has accelerated over time, with significant declines observed between 1999 and 2018.
A large study of collegiate athletes reveals persistent COVID-19 symptoms are rare, but exertional chest pain warrants further clinical evaluation. The study used the Outcomes Registry for Cardiac Conditions in Athletes and found low prevalence of exertional symptoms upon return to exercise.
Researchers at Harvard SEAS developed a new silicon coating that counters chromatic dispersion in transparent materials like glass. The ultra-thin coating uses precisely designed silicon pillars to capture and re-emitting red light, allowing slower-moving blue light to catch up.
A Rutgers University study reveals that volcanic eruptions can cool the climate, weaken monsoons, and reduce crop harvests, making dynasties more susceptible to collapse. The research suggests that smaller eruptions may cause dynasties to fall when political stress is already high.
Researchers investigated how people understand emoji by replacing words with emojis in sentences and measuring reading time. Participants easily understood sentences with emoji, but took longer to read emoji depicting homophones, indicating the image must be interpreted first.
The study reveals that Arabidopsis carboxylesterase 15 (AtCXE15) and its orthologues efficiently hydrolyze plant hormone strigolactones (SLs), regulating shoot branching and plant architecture. This discovery provides a rational approach to manipulating endogenous SLs for crop improvement.
The new standards define key content and processes for accrediting graduate programs in HQS, including 13 competency statements and 4 foundational domains. Accreditation will provide a framework for teaching and training excellence, supporting continuous improvement and culture change in healthcare systems.
A review of 68 studies examining COVID-19 outcomes reveals disparities among patients from diverse racial, ethnic, and socioeconomic backgrounds. The analysis found significant variations in health outcomes, hospitalization rates, and mortality across different demographic groups.
A study found that COVID-19 reduced childhood cancer diagnoses by 17%, but increased intensive care admissions before diagnosis.