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Science News Archive 2024 - Page 482


Page 482 of 484

HKUST researchers develop efficient and accessible single-molecule platform for detecting various amylin species associated with type 2 diabetes

Researchers at HKUST have developed an optical plasmonic tweezer-controlled SERS platform to detect pH-dependent amylin species, revealing the secrets behind amyloid aggregation mechanisms. The platform enables efficient and high-throughput single-molecule characterization of various amylin species.

SourceHong Kong University of Science and Technology·JournalNature Communications·TypeExperimental study·DateJan 4, 2024

The Colorado Center for Personalized Medicine highlighted as a leader in precision medicine in research and clinical care

The Colorado Center for Personalized Medicine has hit a major milestone of returning clinical genetic results to over 30,000 patients, making it a leader in providing personalized patient care. The center is also studying pharmacogenomics and providing results to guide drug selection and dosing.

SourceUniversity of Colorado Anschutz Medical Campus·JournalThe American Journal of Human Genetics·DateJan 4, 2024

Study demonstrates potency of synthetic antibiotic against serious chronic infections

A new synthetic antibiotic teixobactin has been shown to be highly effective against 'superbugs' such as MRSA and bacterial biofilms, which are associated with serious chronic infections. The study's findings provide promising hope for the development of new treatments against multidrug-resistant bacteria and biofilm-related infections.

SourceUniversity of Liverpool·JournalEuropean Journal of Medicinal Chemistry·DateJan 3, 2024

Bacteria load their syringes

Researchers have discovered that bacteria use mobile components of the injectisome to search for and transport specific proteins to be injected into host cells. This mechanism allows for efficient and specific protein delivery, enabling potential applications in medicine and biotechnology.

SourceMax-Planck-Gesellschaft·JournalNature Microbiology·TypeExperimental study·DateJan 3, 2024

Distinct sex differences persist in countries with higher standards of living

Despite improved living conditions, sex differences in personality, verbal skills, and negative emotions are larger in countries with higher standards of living. Women tend to benefit more from these improvements, exhibiting greater altruism and cooperative ability, while men show better cognitive skills but at a smaller advantage.

SourceKarolinska Institutet·JournalPerspectives on Psychological Science·TypeMeta-analysis·DateJan 3, 2024

Cleveland Clinic and University of Western Ontario awarded $4.9 million from the Helmsley Charitable Trust to build Crohn’s disease and ileostomy research consortium

A new consortium, co-led by Florian Rieder, MD, and Vipul Jairath, MD, will create clinical care pathways toward drug development and improve disease management for patients with Crohn's disease and permanent ileostomy. The EndO-trial Consortium aims to develop effective drugs and measure treatment outcomes using patient-reported outco...

Using the body’s own cells to treat traumatic brain injury

Researchers at the Wyss Institute have created a new treatment for traumatic brain injury (TBI) that leverages macrophages to deliver localized anti-inflammatory treatment. The approach reduced lesion size by 56% and significantly decreased local inflammation levels in pigs, offering a promising new direction for TBI treatment.

SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalPNAS Nexus·TypeExperimental study·DateJan 3, 2024

Shining a light on the hidden damage of mild brain injuries

Researchers created a new brain imaging method that allows diagnosis of mild traumatic brain injuries (mTBI) even when existing imaging techniques don't show structural abnormalities. The technique uses immune cells to carry imaging agents into the brain, increasing correctly diagnosed mTBI cases and improving patient care.

SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalScience Translational Medicine·TypeExperimental study·DateJan 3, 2024

Nematode proteins shed light on infertility

Researchers discovered a trio of protein segments guiding chromosomal interactions in nematodes, shedding light on the complex process. The study, published in PNAS, provides new insights into meiosis and infertility, with implications for human reproductive health.

SourceUniversity of Utah·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJan 3, 2024

Researchers identify path to prevent cognitive decline after radiation

Researchers at the University of Rochester Medical Center find that microglia can trigger cognitive deficits after radiation exposure, potentially targeting them for therapy development. Mice studies showed that blocking a specific pathway in microglia prevented cognitive decline, offering hope for improving patients' quality of life.

SourceUniversity of Rochester Medical Center·JournalInternational Journal of Radiation Oncology*Biology*Physics·DateJan 3, 2024

Older adults with newly diagnosed migraine disorder three times more likely to have motor vehicle crash

A new study found that older drivers with newly diagnosed migraines are three times more likely to experience a motor vehicle crash, while those with previous diagnoses are not at increased risk. Researchers also explored the relationship between migraine medications and driving habits, but found no significant impact.

SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of the American Geriatrics Society·DateJan 3, 2024

UT’s Lenhart honored to deliver the American Mathematical Society’s Gibbs Lecture at Joint Mathematics Meeting

Suzanne Lenhart, Chancellor's Professor in UT's Department of Mathematics, will deliver the American Mathematical Society's Gibbs Lecture at JMM2024, recognizing outstanding achievement in applied mathematics. Her lecture explores how mathematical modeling can represent natural system dynamics and guide ecological management strategies.

Genetic variants underlying male bisexual behavior, risk-taking linked to more children, study shows

A new study by University of Michigan researchers found that genetic variants underlying male bisexual behavior are reproductively advantageous, leading to more children and increased risk-taking. The analysis of over 450,000 participants revealed a correlation between these alleles and higher fertility rates in heterosexual men.

SourceUniversity of Michigan·JournalScience Advances·TypeSurvey·DateJan 3, 2024

Researchers improve seed nitrogen content by reducing plant chlorophyll levels

By reducing chlorophyll levels in leaves, researchers found a 17% increase in seed nitrogen concentration without impacting canopy carbon assimilation. The study's results provide an alternative approach to improve crop yield and nutritional quality for global food security.

SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalPlant Cell & Environment·TypeExperimental study·DateJan 3, 2024

Chronic childhood ear infections delay language development

A new study from University of Florida scientists reveals that chronic ear infections can lead to deficits in auditory processing and language development in children years later. Children with multiple ear infections before three years old had smaller vocabularies and difficulty matching similar sounding words.

SourceUniversity of Florida·JournalInternational Journal of Pediatric Otorhinolaryngology·TypeData/statistical analysis·DateJan 3, 2024

Korea Maritime & Ocean University researchers develop a new method for path-following performance of autonomous ships

Korea Maritime & Ocean University researchers have developed a new method for assessing the path-following performance of autonomous ships in adverse weather conditions. The computational fluid dynamics model can provide more accurate predictions of path-following performance and enhance safety in autonomous marine navigation.

SourceNational Korea Maritime and Ocean University·JournalOcean Engineering·TypeComputational simulation/modeling·DateJan 3, 2024

Early primates likely lived in pairs

A recent study suggests that many nocturnal Strepsirrhines live in pairs of males and females, challenging the long-held assumption that these primates are solitary. Researchers found that pair-living was the most common social organization among ancestors 70 million years ago.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·TypeMeta-analysis·DateJan 3, 2024

Some sea cucumbers like it hot

A team of scientists sequenced the full genome of a sea cucumber collected at a hydrothermal vent, revealing expanded gene families involved in DNA repair and iron metabolism. The research provides valuable insights into the unique adaptations of marine animals to survive in extreme environments.

SourceGigaScience·JournalGigaScience·TypeExperimental study·DateJan 3, 2024

Fitness with no age limit

The MU Extension program has proven results, showing improvements in physical energy, self-confidence, and muscle strength among participants. The program also reduces the risk of falling and provides social enjoyment for participants, who often form close relationships with instructors and each other.

SourceUniversity of Missouri-Columbia·JournalJournal of Applied Gerontology·TypeObservational study·DateJan 3, 2024

An electrophysiological breakthrough for diabetic brain studies

Researchers developed a novel low-invasive neural recording technique for diabetic mice, overcoming tissue damage and enabling stable recordings for an entire month. This breakthrough technology has significant potential for broader applications, including drug discovery and brain-machine interface development.

SourceToyohashi University of Technology (TUT)·JournalBiosensors and Bioelectronics·TypeExperimental study·DateJan 3, 2024

Research reveals promising approach to enhance treatment for sleep apnea-related issues

A groundbreaking study found that combining partial normoxic recovery with senolytic Navitoclax significantly reduced sleepiness and improved cognitive function in mice with OSA. This suggests targeting accelerated senescence may be a promising avenue for improving treatment outcomes.

SourceMarshall University Joan C. Edwards School of Medicine·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJan 3, 2024

Job ads with wide pay ranges can deter applicants

A Washington State University study found that job ads with very wide pay ranges evoked less favorable impressions of employers. Participants viewed these ads as less trustworthy and doubted the organization would offer high salaries to employees. However, some saw the large range as a positive sign of possible 'room for growth',

SourceWashington State University·JournalJournal of Applied Psychology·DateJan 3, 2024

Pain is a major problem for individuals with traumatic brain injury

A new study published in The Journal of Head Trauma Rehabilitation found that approximately 60% of people living with traumatic brain injury (TBI) experience chronic pain, even up to 30 years after injury. Chronic pain can significantly worsen outcomes for individuals with TBI, and medications are often the most frequently used treatment.

SourceWolters Kluwer Health·JournalJournal of Head Trauma Rehabilitation·DateJan 3, 2024

Novel genetic priority score unveiled to enhance target prioritization in drug development

Researchers at Icahn School of Medicine at Mount Sinai developed a novel genetic priority score (GPS) to integrate various types of human genetic data for easy target prioritization. The tool identifies genes with high potential for clinical trial success, particularly those with demonstrated genetic support.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature Genetics·TypeComputational simulation/modeling·DateJan 3, 2024

Using static electricity to enhance biomedical implant durability

A research team developed electrostatic materials capable of responding to weak ultrasound, generating static electricity for implantable neurological stimulators. The technology eliminates the need for batteries, reduces device size, and minimizes strain on the human body. Experimental validation confirms its effectiveness in animal m...

Mount Sinai study shows that human beliefs about drugs could have dose-dependent effects on the brain

A Mount Sinai study found that human beliefs about nicotine can modulate brain activities in a way comparable to pharmacology, with potential implications for addiction treatment. The study used fMRI to explore the relationship between subjective beliefs and biological substrates in the human brain.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature Mental Health·TypeObservational study·DateJan 3, 2024