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Science News Archive 2025 - Page 360


Page 360 of 574

Illinois researchers develop next-generation organic nanozymes and point-of-use system for food and agricultural uses

The University of Illinois researchers have developed organic-material-based nanozymes that can detect histamine in food products with an affordable analytic performance profile. An integrated point-of-use platform allows for rapid detection of agricultural and biological molecules without laboratory equipment.

Hepatic biliary adenofibroma: Histological characteristics, diagnostic challenges, and its role as a precursor to intrahepatic cholangiocarcinoma

Hepatic biliary adenofibroma (BAF) is a rare, benign tumor with histological characteristics distinct from other biliary tumors. Emerging case reports suggest potential for malignant transformation and overlap with intrahepatic cholangiocarcinoma (iCCA), highlighting diagnostic challenges and need for further research.

SourceXia & He Publishing Inc.·JournalJournal of Clinical and Translational Pathology·DateFeb 28, 2025

TTUHSC conducting study to help patients that experience traumatic blood loss

The Texas Tech University Health Sciences Center is conducting a randomized controlled trial to investigate the effectiveness of calcium and vasopressin in treating severely injured patients who experience significant blood loss. The study, known as CAVALIER, will enroll approximately 1,050 participants aged 18-90.

SourceTexas Tech University Health Sciences Center·TypeRandomized controlled/clinical trial·DateFeb 28, 2025

Ursodeoxycholic acid for the management of drug-induced liver injury: Role of hepatoprotective and anti-cholestatic mechanisms

Ursodeoxycholic acid (UDCA) exhibits a broad range of hepatoprotective mechanisms, including antioxidant, anti-inflammatory, and anti-apoptotic properties, which may benefit various types of drug-induced liver injury. In hepatocellular DILI, UDCA reduces inflammation, alleviates ER stress, and protects against mitochondrial damage. In ...

SourceXia & He Publishing Inc.·JournalJournal of Clinical and Translational Hepatology·DateFeb 28, 2025

After NIH decision to cap indirect costs, prominent molecular biologist calls for swift action, petition signatures

Tom Maniatis, a prominent molecular biologist, is warning of the impact of the NIH's planned 15% cap on indirect costs. He believes small independent institutions will be harmed, stifling technological innovation and scientific progress. The scientific community must act swiftly to prevent this from happening.

SourceCell Press·JournalCell·TypeCommentary/editorial·DateFeb 28, 2025

A dictionary of fragrances

Scientists at Friedrich-Schiller-University Jena have developed data sets for the description and recording of odours, using over 1,200 test subjects to compile how people perceive, describe, and classify 74 monomolecular odour samples. The researchers aim to help solve the stimulus-percept problem in smell perception.

SourceFriedrich-Schiller-Universitaet Jena·JournalScientific Data·TypeRandomized controlled/clinical trial·DateFeb 28, 2025

Relapsing polychondritis: Tracheobronchial involvement and differential diagnoses

Tracheobronchial involvement in relapsing polychondritis requires a multimodal approach for diagnosis and treatment. Key findings include the use of dynamic thoracic imaging and flexible bronchoscopy to assess lesions, as well as the development of immunosuppressant therapies such as TNF-α inhibitors to improve prognosis.

SourceNational Center for Respiratory Medicine·JournalJournal of Thoracic Disease·TypeLiterature review·DateFeb 28, 2025

Development of 'transparent stretchable substrate' without image distortion could revolutionize next-generation displays

Researchers at KIST have developed a transparent, distortion-free, and non-deformable display substrate by reducing Poisson's ratio to 0.07 or less. The nanostructure-aligned substrate was found to have little longitudinal shrinkage, even when stretched by over 50%, resulting in unbroken images and transparency.

Large population study identifies long-term health risks after COVID-19 hospitalization

A nationwide study found that COVID-19 hospital patients experienced a higher rate of deaths from any cause and were more likely to be hospitalized for specific conditions, particularly neurological and respiratory problems. The study also identified increased risks of chronic health complications up to 30 months after discharge.

SourceTaylor & Francis Group·JournalInfectious Diseases·TypeObservational study·DateFeb 28, 2025

The math behind social distancing: the rules that influence epidemic behavior

A research team identified simple rules governing decision-making during epidemics, which balance infection costs and social distancing. The guidelines predict population behavior based on disease reproduction number and infection cost, offering a new tool for governments to design intervention strategies.

SourceInstitute of Industrial Science, The University of Tokyo·JournalProceedings of the National Academy of Sciences·DateFeb 27, 2025

Progentos Therapeutics CEO Chris Loose named board member and chair of the Fellowship and Programs Council for Hertz Foundation

Chris Loose, Progentos Therapeutics CEO, is now chair of the Hertz Fellowship and Programs Council. He will oversee the selection process, administer awards, and facilitate connections among Hertz Fellows. The Hertz Foundation aims to empower innovative scientists and technologists through its prestigious fellowship program.

Element relational graph-augmented multi-granularity contextualized encoding for document-level event role filler extraction

A novel method, ERGM, was proposed for document-level event role filler extraction. It substantially outperforms strong baseline models and effectively captures dependency relationships between different event roles. The explicit graph-structured representation generated by a graph neural network is key to its success.

SourceHigher Education Press·JournalFrontiers of Computer Science·TypeExperimental study·DateFeb 27, 2025

How the nervous system modulates pain signals

Researchers at Thomas Jefferson University discovered a specific molecular change that affects the strength of pain sensation by altering action potential duration. This finding offers a novel approach to alleviate clinically relevant pain conditions through boosting potassium channel function.

SourceThomas Jefferson University·JournalProceedings of the National Academy of Sciences·DateFeb 27, 2025

Guidelines for the creation of accessible consent materials and procedures: Lessons from research with autistic people and people with intellectual disability

The article presents guidelines for designing consent materials and procedures for autistic adults and people with intellectual disability, highlighting the importance of multiple modes to deliver content. These guidelines aim to improve accessibility and respectfulness in research with individuals on the autism spectrum.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalAutism in Adulthood·TypeContent analysis·DateFeb 27, 2025