Scientists have uncovered ancient TIGR systems, which use RNA to guide protein modification of DNA in human cells. These compact and modular systems can target any DNA sequence with high precision, making them a promising tool for therapeutic deployment.
A survey of over 1,000 professional women found that remote work significantly reduces everyday gender discrimination. On-site, women experience 31% more gender discrimination than while working remotely.
Researchers discovered how air pollution and wildfire smoke can trigger S-nitrosylation of a key brain protein, preventing brain cells from making new connections. Blocking this chemical modification partially reversed signs of memory loss in Alzheimer's mouse models and nerve cells.
Mayo Clinic has been recognized as the world's best hospital for the seventh straight year by Newsweek, with a focus on delivering compassionate care to patients. The institution prioritizes innovation in clinical practice, education, and research to transform healthcare.
A large-scale study found that people who engage in moderate to vigorous physical activity have a lower risk of developing dementia, stroke, anxiety, depression, and sleep disorders. The study also discovered that spending more time sitting increases the risk of developing these diseases.
A new study found that Medicaid extension policies covering all immigrants led to a 4 percentage-point decrease in postpartum uninsurance among immigrant populations in New York City. However, Hispanic immigrants saw a smaller decline, highlighting awareness gaps as a barrier to full benefit.
Researchers at the National Institutes of Health (NIH) have created a four-dimensional brain map that reveals how lesions similar to those seen in human MS form. The findings provide insight into early disease state changes and could help identify potential targets for MS treatments and brain tissue repair.
Researchers found that training the innate immune system can exacerbate inflammatory bone loss in models of chronic diseases like periodontitis and arthritis. The study suggests that a previously thought beneficial effect of trained immunity may actually contribute to harm in certain contexts.
The Center for Achieving Resilience in Climate and Health (C-ARCH) will identify ways to build resilience, design evidence-based solutions, and train scientists to lead the response. C-ARCH aims to address the devastating health impacts of climate change worldwide.
A study published in BMC Biology found that different scientists working with the same datasets can arrive at vastly different results, emphasizing the importance of transparent analysis methods. The findings raise fundamental questions about reproducibility and reliability in scientific results.
The Global Pediatric Pulmonary Alliance recommends prophylactic mAbs as the best available preventive measure against RSV. A single dose of long-acting mAbs can provide season-long protection to infants, with real-world evidence supporting this strategy.
Researchers at AWS and Caltech developed a new cat qubit chip, called Ocelot, to suppress errors in quantum computers. The chip uses superconducting circuits to create stable qubits resistant to bit-flip errors.
A comprehensive phylogeny of living Mollusca resolves complicated relationships among eight classes, including bivalves and cephalopods. The study supports a Cambrian origin for Mollusca, with key clades Aculifera and Conchifera emerging rapidly.
A recent study by Indian Institute of Science found that tropical lizards, such as rock agamas, prioritize variable food sources over constant ones when hungry. This flexible approach helps them thrive in unpredictable conditions.
A new study reveals detailed insights into polar bear denning behavior, showing altered emergence periods and variable den presence. The research highlights the importance of protecting denning areas to ensure cub survival and species conservation.
Researchers propose a swarm-intelligence collaboration to optimize precast component production scheduling and rescheduling. The approach uses dynamic-interval synergy auctions and weighted Tchebycheff approaches to generate optimal schemes, improving management efficiency and reducing costs in prefabricated building project management.
Researchers have developed a method to observe quantum interference in surface collisions of methane molecules, revealing clear patterns of wave-like behavior that amplify or cancel out different pathways. This discovery confirms the active role of quantum mechanics in controlling molecular interactions at surfaces.
Researchers developed a nanoplatform that combines photothermal, photodynamic therapies with imaging capabilities to treat cancer. The platform achieved synergistic anticancer effects by inducing a switchable response in the tumor microenvironment.
Researchers used DNA barcodes to narrow down the possible sources of introductions of an invasive banana skipper butterfly, finding evidence of aircraft-borne introductions in Japan and potentially in Mauritius. The study suggests that gravid females may be attracted to airport lights, increasing the risk of spread to new areas.
A large-scale analysis sheds light on the critical steps needed to combat the vertical transmission of chronic hepatitis B virus (HBV) in Africa. The study estimates that hepatitis B vertical transmission could be eliminated in Africa with increased coverage of birth dose vaccine and maternal antiviral therapy.
The American Society for Radiation Oncology (ASTRO) has published its first clinical guideline on radiation therapy for anal cancer, providing guidance on treatment options and techniques. The guideline recommends a combination of radiation therapy and drug therapy as the standard of care, with intensity-modulated radiation therapy (IM...
University of Missouri researchers developed a solution to improve solid-state battery performance by understanding the root cause of issues. They used 4D STEM to examine atomic structures without disassembling batteries, ultimately determining the interphase layer was the culprit.
The Association for Computing Machinery's Technology Policy Council issues brief calls on policymakers and tech companies to address tech abuse in intimate partner violence, human trafficking, and child exploitation. The report highlights disturbing statistics and recommends expanding laws and regulations to protect users.
A new University of Texas at Arlington study reveals high concentrations of microplastics in bird lungs, with average particles per species and gram of lung tissue measured. The study highlights the urgent need to address plastic pollution and its far-reaching impacts on ecosystem health and human health.
Researchers discuss innovative ways to address social isolation and loneliness in psychiatric illness through pharmacologic compounds. The Brain & Behavior Research Foundation invites the public to a free webinar on March 11, 2025, featuring Dr. Anya Bershad's latest findings.
Surgical adhesions form after surgery, causing severe complications like bowel obstructions, chronic pain, and infertility. A new report explores solutions to this widespread problem, including the development of standardized tools and innovative treatments.
A cohort study of 46,000 US residents found nearly two-thirds had suboptimal 5-year sleep duration trajectories, associated with increased risk of mortality. Maintaining healthy sleep duration is crucial for reducing mortality risk in this population.
Enodia Therapeutics, launched by Institut Pasteur and Argobio, leverages AI to develop selective inhibitors of the Sec61/translocon molecular complex for treating cancer, inflammatory diseases, and viral infections. The company's breakthrough technology has earned a prestigious Golden Ticket Award from Pfizer.
Researchers used molecular modeling techniques to understand nanoplastic interactions with natural organic matter in aquatic ecosystems. The study found that aged nanoparticles form stable aggregates through a combination of intermolecular forces, including hydrogen bonding and cation bridging.
Scientists discovered a protective variant of the HAQ-STING gene that prevents COPA Syndrome. This finding opens the door to a new gene therapy for the condition, which currently has no cure.
The Advisory Committee on Immunization Practices (ACIP) plays a crucial role in developing vaccination recommendations based on scientific evidence. SHEA advocates for timely rescheduling of the meeting to provide healthcare providers with the latest updates and reduce outbreaks from preventable diseases.
A recent study suggests that AI systems replicate and amplify existing social inequalities when left unchecked, particularly in high-stakes areas like hiring and welfare distribution. The researchers argue for the need for greater transparency, inclusivity, and accountability in AI governance to ensure its use serves social justice.
Key molecular applications in diagnosing and managing hematopoietic and lymphocytic neoplasms include comprehensive mutational profiling, aiding accurate diagnosis and prognostication. The use of targeted therapies against specific genetic abnormalities further refines treatment selection.
The researchers used high-speed laser writing to create lines spaced just 100 nm apart on a glass substrate, achieving super-resolution 3D direct laser writing. They overcame the challenge of intense laser light causing unwanted exposure in nearby areas by using a unique dual-beam optical setup and special photoresist.
A new study finds that precession initiates deglaciation while obliquity triggers interglacial conditions. The researchers used benthic oxygen isotope records to quantify glacial transitions and estimate the next glacial period will begin in 11,000 years.
A new study reveals that overusing genetically engineered corn resistant to rootworm pests has reduced farmers' profits in the Midwest. The research found that pest pressure has shifted towards other areas, making the technology less effective, and its use has become increasingly costly.
Researchers from ANU and international partners have identified a common 'weapon' used by disease-causing fungi to infect plants. This discovery could lead to the development of more resilient rice crops and other fruit and vegetable staples, bolstering global food security.
Researchers investigated two commercial veterinary listeriosis vaccine strains, revealing they belong to different phylogenetic lineages. The attenuated strains demonstrated distinct morphological characteristics when grown on bacterial media. These findings highlight the genetic diversity of Listeria monocytogenes used in vaccines.
A new study published in Cell Press journal suggests that the International Space Station is overly sterile, and introducing more natural microbes could help astronauts. Researchers found that human skin was the main source of microbes on the ISS, while chemicals from cleaning products were ubiquitous.
The Finnish Institute for Health and Welfare has published a governance model for the wellbeing economy, which aims to balance social, economic, and ecological sustainability in national-level decision-making. The model proposes using citizens' consultation processes and long-term wellbeing targets to guide government programs.
Dr. Casal García's work has revealed a significant shift in stride patterns of female elite athletes during 400 meter hurdle competitions, leading to improved performances. Her research aims to tailor athlete training based on individual characteristics, bridging the gap between academia and practical application.
The AAIF2025 conference will bring together experts in actin biology from around the world to present latest research and discuss directions. The meeting will feature 27 invited speakers, short presentations, poster sessions, and social events.
The joint research aims to connect multiple quantum devices in practical environments, enhancing processing capabilities and enabling flexible operation. The collaboration will focus on intra-site connections and connections between neighboring cities to develop scalable quantum information processing technologies.
A recent study by Janelia researchers found that the striatum and motor cortex collaborate to specify movement parameters, contradicting traditional theories. This discovery sheds light on the role of the striatum in motor control and could lead to better understanding of movement disorders like Parkinson's and Huntington's.
Researchers develop plant-based adhesives, self-bonding bamboo fiberboards, thermally insulating cardboard foams, and wood-derived hydrogels for repairing joints, offering promising solutions to recycling challenges in furniture and building insulation.
A new MSU-led study found that translocation successfully bolstered population numbers, but failed to prevent genetic erosion and inbreeding in Florida Scrub-Jays. The researchers analyzed decades' worth of data and sequencing the entire genomes of 87 jays, identifying reproductive skew as a limiting factor.
A new study discovered that violence can alter human genes for generations, even in grandchildren who never experienced violence themselves. Researchers found epigenetic changes in the genomes of Syrian families affected by the Hama massacre and subsequent civil war.
A new study found that patients with depression from high-wealth neighborhoods in Maryland were significantly more likely to have telehealth visits compared to those from low-wealth neighborhoods. This trend suggests that telehealth may not be improving access to care for all patients, especially those living in disadvantaged areas.
This study investigates coumarin derivatives as MAO inhibitors, revealing phenyl substitution's impact on inhibitory activity and selectivity. The findings provide new insights into the interactions between coumarins and MAOs, contributing to the development of coumarin-based MAO inhibitors.
Rare genetic diseases affect 300 million people globally, with one in three dying before age five. Global collaborations are transforming clinical care by leveraging genomic technologies and evidence-based approaches.
The study reveals a dynamic ecosystem with diverse dwarf galaxies, unlike the Milky Way's smaller satellite system. Hubble's observations provide insights into how small-galaxy growth is affected by massive galaxies like Andromeda.
A new stem cell transplant treatment has shown promising results in clearing clinical safety hurdles for the treatment of wet age-related macular degeneration. The treatment involves removing abnormal blood vessels and transplanting stem cell-derived retinal cells to replace damaged or lost retinal cells.
Advanced simulations reveal that PMOs form directly from disk interactions, inheriting material and moving synchronously with host stars. This discovery reshapes our understanding of cosmic diversity, suggesting a new class of objects born from gravitational chaos.
A new deep learning framework empowers microswarm robots to adaptively navigate complex environments, ensuring safe and efficient navigation. The approach excels in online planning and dynamic scenarios, with a high search success rate of over 92%.
A recent study highlights the unique challenges facing Sydney's koala population, which is one of the last strongholds for New South Wales' koalas in NSW. The populations have low genetic diversity, making them highly susceptible to environmental threats and disease outbreaks.
Symplectic Elements now offers AI-generated summaries for publication abstracts, enhancing public profiles and increasing research visibility. The new functionality supports researchers and institutions in showcasing their research outputs and discoverability.
Researchers developed a FeCo alloy catalyst encapsulated in graphene layers, achieving efficient CO2 conversion to light olefins. The catalyst showed high performance with 52.0% CO2 conversion and 33.0% selectivity to light olefins.
Researchers developed a deep-learning framework, STAIG, to automatically map distinct genetic activity to tissue regions without manual alignment. The study demonstrates superior performance across various conditions, showcasing its potential for cancer research and understanding complex biological systems.
A new survey found that patients with neurological and mental health disorders prefer non-invasive neuromodulation interventions over current medications. The study, published in Scientific Reports, suggests that providing accurate information to patients improves their perception of these treatments.
The review article explores multiphoton polymerization's potential in precision medicine, highlighting its noncontact, high-precision molding capabilities and diverse biomedical applications. However, challenges such as biosafety and cost issues need to be addressed for widespread adoption.