A comprehensive genetic analysis of East Asian populations has identified key SORL1 genetic variants that confer protective effects against Alzheimer's disease. Individuals carrying these variants exhibited improved cognitive function, decreased neurodegeneration, and less severe AD pathology.
Cardiac arrhythmia disrupts heart rhythm due to malfunctioning electrical impulses. Rui Zhu plans to use deep-learning and computational simulations to model diseased hearts and understand multi-physical factors contributing to arrhythmic conditions.
A large study published in BMJ Mental Health found clear time of day patterns in frame of mind, with people generally waking up feeling best in the morning and worst around midnight. The study also revealed seasonal influences on mental health and wellbeing, with better mood during summer months.
The Neuro-Oncology Translational Research Training Program aims to bridge laboratory discoveries and clinical applications in neuro-oncology, targeting glioblastoma and brain metastases. The program provides predoctoral and postdoctoral trainees with cutting-edge lab experience and mentorship across multiple disciplines.
Two new celestial objects have been confirmed using Gaia data, including a Super-Jupiter exoplanet and a brown dwarf. The discovery challenges current theories of planet formation and provides valuable data for understanding these intriguing objects. Gaia's ongoing mission will uncover hundreds of planets and brown dwarfs around nearby...
A new Journal of Marketing study reveals that 'buy now, pay later' installment payments can significantly increase customer spending. The research found that by spreading payments into interest-free installments, retailers can boost both the number and average amount spent on purchases.
A study reveals that large cities have ceased to be centers of upward social and economic mobility, with population density and connectedness associated with reduced intergenerational mobility. Urban expansion has also led to decreased average social capital, contributing to growing inequality within and across generations.
A new study found that yo-yo dieting significantly increases the risk of kidney disease in people with type 1 diabetes. Participants who experienced greater weight fluctuations had a 40% decline in estimated glomerular filtration rate and were more likely to exhibit increased albuminuria.
A scoping review found women health sector leaders have a positive impact on financial performance, innovation and health outcomes, despite being underutilized. Increased investment is needed to maximize their potential and reap benefits.
A team of physicists at the University of Vienna created an innovative device that uses spin waves to perform multiple data processing tasks with exceptional energy efficiency. The 'universal' device has significant potential for next-generation telecommunications, computing, and neuromorphic systems.
Yann LeCun, NYU's Courant Institute of Mathematical Sciences professor, has been selected as a winner of the 2025 Queen Elizabeth Prize for Engineering for his groundbreaking research on artificial neural networks. His work enabled machines to process and learn from vast amounts of data in ways previously unimaginable.
Researchers developed a smart patch that integrates sensors and drug delivery systems, enabling real-time biometric signal monitoring and immediate drug administration. The technology has high applicability across various medical fields, including glucose management and chronic disease treatment.
Researchers at Ohio State University have developed a new portable tool that can deliver conductive aerosols to suppress flames using the power of vortex rings. The device was tested in two prototypes, both of which had an effective range of nearly 2 meters, and showed promise in suppressing fires.
Researchers found that playing classical music can smooth variations in fetal heart rates, indicating potential benefits for fetal development. The study used mathematical analysis tools to identify patterns in heart rate variability and found that exposure to music resulted in more stable and predictable patterns.
Women who experience late-onset menopause have significantly better vascular health and are less likely to develop heart disease than those who experience it earlier. The study found that preserved mitochondrial function and certain lipid levels in their blood may contribute to this protection.
A team of engineers from the University of Texas at Austin used x-ray, infrared, and other imaging technologies to investigate battery degradation in wireless earbuds. They found that temperature gradients, caused by clashes between critical components and the battery, led to damage and reduced battery life.
A recent study published in Seismica journal has debunked claims that a magnitude 4.5 earthquake in Iran was a covert nuclear weapons test. The researchers analyzed seismic signals from the event and concluded that it was caused by natural geological forces, contradicting widespread misinformation on social media and news outlets.
Nanomaterials are being studied for their potential in combating marine oil spills, with promising results showing improved removal efficiency and reduced toxicity. The researchers emphasize the need for eco-friendly and sustainable approaches to minimize environmental risks.
A new study from Michigan State University reveals that social media plays a crucial role in connecting students with disabilities to others who share similar experiences. The research found that students with disabilities use social media as a tool for self-advocacy, identity exploration, and accessing vital resources.
The AI-powered tool, ReCOGnAIze, uses neuroscientific games to identify early signs of cognitive impairment in just 15 minutes, achieving nearly 90% accuracy. This scalable and cost-effective solution aims to improve quality of life for individuals with mild cognitive impairment.
Eye saccades enable mammals to chase prey and navigate through complex environments by aligning with optic flow, reducing motion blur. This mechanism allows animals to track erratic movements and react flexibly to changes in direction.
Dr. Kerry Ressler's research bridges the gap between molecular neuroscience and clinical psychiatry to understand PTSD's genetic architecture. Recent breakthroughs have identified over 100 significant genetic loci, representing a major step toward translating scientific discoveries into effective treatments.
Researchers at University of Oxford critically evaluated CITES effectiveness, highlighting critical flaws in state-led law enforcement approach and socio-economic analysis exclusion. They propose a new decision support tool based on inclusive governance processes to revise or redesign CITES rules and regulations.
Researchers at Queensland University of Technology have developed a novel biosensor that can selectively detect rare earth elements. The biosensor is based on molecular nanomachines engineered by the team, which produce easily detectable signals when binding to lanthanides.
Researchers from Binghamton University discovered that connecting people with similar views or backgrounds leads to less diverse ideas. Conversely, interacting with a limited number of others produces higher-quality ideas. The study suggests that promoting biodiversity through idea generation is key to achieving optimal results.
Researchers discovered that a topical ABT-263 treatment effectively reduces aged skin senescence markers, priming the skin for improved subsequent wound healing. The treatment also triggered inflammation, which surprisingly helped the healing process by 'waking up' the skin's repair systems.
Teams from HZB and Humboldt University Berlin have developed a new tandem solar cell combining CIGS with perovskite, achieving a world record efficiency of 24.6%. This breakthrough could lead to higher efficiencies of over 30%, making CIGS-perovskite tandem cells a promising technology for sustainable energy solutions.
Researchers discover how an anticancer drug triggers an 'outside in' signal to get sucked into a cancer cell, providing insights into adhesion regulation and potential drug design targets. The study reveals a new mechanism for delivering drugs using P-cadherin protein.
A large observational study found that high levels of 'good' HDL cholesterol are associated with a heightened risk of glaucoma, particularly among those older than 55. In contrast, higher levels of 'bad' LDL cholesterol, total cholesterol, and triglycerides are linked to a lower risk of the condition.
The hospital was ranked highly among healthcare professionals in the US and globally, reflecting its commitment to compassionate care and innovative research. UH Cleveland Medical Center is affiliated with several top medical schools and institutions, further solidifying its reputation as a leading Academic Medical Center.
The Off the Field National Football League Wives Association partnered with the American Heart Association and other organizations to promote water safety skills among children. The event, held in New Orleans, provided Hands-Only CPR and automated external defibrillator education.
Scientists at The Hospital for Sick Children have discovered a way to stop tumour growth before it starts for a subtype of medulloblastoma, the most common childhood malignant brain cancer. By blocking a key protein responsible for waking 'sleeping' stem cells, the study demonstrates a novel strategy to target cancer stem cells.
Researchers found a strong association between asthma and repeated antibiotic use in predicting nasal polyp recurrence after endoscopic sinus surgery. The study suggests that patients with severe chronic rhinosinusitis with nasal polyps may benefit from additional treatments like biologics to manage the disease.
Early-career scientists are vulnerable to deteriorating employment conditions and pressure to meet tight deadlines. FRONTIERS offers immersive experiences at the forefront of knowledge to inspire and nurture the next generation of science journalists.
Researchers at Washington State University have created genetically engineered mice with human-like short telomeres, enabling the study of cellular aging as it occurs in humans. The new mouse model, called HuT mice, has significant implications for anti-aging research and cancer treatment.
Researchers analyzed data from 8,843 women with preeclampsia to evaluate the performance of existing risk prediction models. The study found that these models are most accurate only in the days following diagnosis and deteriorate over time.
Researchers found that a machine learning predictive model leveraging EHR data outperformed screening surveys in identifying patients with health-related social needs. The models demonstrated biases, particularly towards White, non-Hispanic patients.
McGill researchers found that music at an individual's natural tempo significantly reduces pain perceptions. The study discovered the greatest reductions in pain levels occurred when melodies were played at a rate matching the participant's own preferred tempo.
The Primary Prevention Trial aims to determine whether stopping early molecular changes can prevent Alzheimer's disease from taking hold. The study will enroll people as young as 18 with few or no detectable Alzheimer's-related molecular changes in their brains.
A recent UBC study found that there's a 26% annual chance of space rocket junk re-entering the atmosphere and passing through a busy flight area, highlighting the potential for uncontrolled debris to disrupt flights. The researchers emphasize the need for policymakers to take action to address this issue.
A new law in Utah allows minors to revoke their informed consent for gender-affirming care, casting a cloud over the trusted process between doctors and patients. This legislation puts clinicians at risk of litigation and may limit access to necessary medical treatments.
The researchers developed a system that generates electricity and light simultaneously using motion and pressure, stably producing up to 60V and 395nA without degrading performance. This technology has the potential to improve safety in disasters and sports, as well as reduce environmental impact through energy harvesting.
Researchers developed surface-modified apatite coatings using pH control to enhance cell adhesion and improve the biocompatibility of implants. The study found that controlling the nanoscale surface layer of apatite nanoparticles leads to better binding affinity with biological tissues.
A POSTECH research team developed a novel multidimensional sampling theory to overcome limitations of flat optics. Their study identifies constraints of conventional sampling theories and presents an innovative anti-aliasing strategy, significantly enhancing optical performance.
A new study by Stanford University researchers found that coal-fired power stations drag down annual wheat and rice yields by 10% or more due to NO2 emissions. Eliminating these emissions could boost rice output by $420 million per year and wheat output by $400 million per year.
A recent study published in Communications Biology reveals that the Sudan virus binds to human cells through a specific protein called NPC1, which enables it to attach with nine times greater affinity than Ebola. This discovery may contribute to the high fatality rate of the Sudan virus.
A potential new therapy, CT-179, effectively targets tumor cells and disrupts cancer stem cells, leading to improved treatments and increased survival rates. The novel drug, developed by Curtana Pharmaceuticals, may bring new efficacy to brain tumor therapy.
Researchers at FAU's Schmidt College of Medicine will explore the use of genetically engineered cells to treat degenerative diseases, with a focus on understanding how hypoxic conditions drive cellular transformation. The study aims to identify novel pathways controlling this process and develop strategies for engineering more complex ...
Researchers aim to develop room-temperature superconductors using AI and quantum geometry, potentially revolutionizing energy efficiency. The project aims to push boundaries of quantum materials science and superconductivity.
A new Stanford study suggests refining how we assess natural carbon storage strategies to ensure the technology lives up to its potential as a climate change solution. The researchers propose a two-step evaluation process to unlock additional project value and improve data for predictive modeling.
The number of family caregivers supporting older adults living in home and residential-care settings increased to 24.1 million, a 32% rise from 18.2 million in 2011. Caregiving responsibilities continued to fall primarily to women, with those caring for individuals with dementia facing unique challenges.
Researchers at the CNIC have designed a treatment strategy to protect the heart against cardiotoxic effects of anthracyclines, a common class of anticancer drugs. Empagliflozin, an SGLT2 inhibitor, has been shown to preserve cardiac function and metabolism in experimental models.
Researchers at University of California San Diego have discovered the transformation process of healthy stem cells to cancer stem cells in oral cancer. By activating YAP and HPV oncogenes, normal stem cells are reprogrammed into cancer cells, leading to early-stage tumor initiation.
Researchers have created detailed maps of the retina using AI technology to better understand its link to various diseases. The study identified new genetic factors influencing retinal thickness, which may serve as a diagnostic biomarker for disease detection.
The Human Virome Characterization Center at UCLA will investigate the diversity of viruses naturally inhabiting the human body along the oral-gut-brain axis. The center's discovery team will characterize virome richness, diversity, and structure in healthy individuals across different age groups and ethnic backgrounds.
A new study identified USP5 as an enzyme crucial for breaking down unneeded or damaged proteins in the heart. Low levels of USP5 lead to protein buildup, triggering dilated cardiomyopathy in animal models. Increasing USP5 levels helps clear protein 'junk', improving heart function and reducing disease progression.
The Hubble Space Telescope has captured a cosmic bullseye, revealing eight visible rings and confirming a ninth using data from the W. M. Keck Observatory in Hawaii. The galaxy's unique ring structure was formed by a blue dwarf galaxy colliding with its center, creating a new generation of stars.
Researchers discovered that Wnt3 coordinates a two-step process of cell polarity orientation, enabling jellyfish embryos to develop around a central axis. This discovery sheds light on the evolution of body plans in early animals and may provide insights into cellular-level organisation.
A study on painted lady butterfly migrations found that environmental conditions, rather than genetic coding, drive their migratory patterns. The research revealed that butterflies can travel vast distances, crossing the Sahara Desert, without showing significant genomic differences between short and long-distance migrants.
Researchers at the University of Texas at El Paso developed a novel method to measure load demand on the electrical grid for electric vehicles charging while in motion. The model, called modified Toeplitz convolution or mCONV, accounts for varying vehicle sizes, road lengths, and traffic flow.