Multiple Sylvester physicians presented their research on various hematological cancers, including lymphoma and myeloma. The studies showcased promising results for treatments such as CAR-T therapy and immunotherapy combinations.
Researchers discovered a new optical principle to amplify light in water using non-harmonic two-color femtosecond laser excitation. This breakthrough achieves a 1,000-fold enhancement in broadband white-light output and unlocks advances in bioimaging and ultrafast spectroscopy.
A study from OIST shows that abrasion from common additives can lead to efficient reactions under mechanochemical conditions. Abrasive materials like tungsten carbide or diamond powder activate catalysts and drive coupling reactions. This finding changes the way researchers think about mechanochemical catalysts.
Neural signals respond differently depending on time of day, with reduced activity at sunrise and enhanced at sunset. Blocking adenosine reveals a key regulator of cortical excitability across the day.
Using stress cardiac MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life for people with suspected angina. The test can help identify small vessel problems that may be causing chest pain, which are often under-recognized in women and other groups.
A new study found that providing healthy, medically tailored meals and fresh produce boxes along with nutrition counseling can improve the quality of life for people with heart failure. The 90-day trial showed significant benefits compared to dietary counseling without food delivery.
A population-based cohort study found that the cumulative incidence of scrotal surgery among male living kidney donors was 1 in 8 after 20 years, compared to 1 in 143 for non-donors. Most males who donate a kidney won't develop this complication, but it's essential to inform past and future donors about the risk and potential symptoms.
Researchers found a novel link between shared brain-gene patterns and autism symptom severity in children with autism and ADHD. The study suggests that focusing on specific symptom dimensions and their biological correlates may lead to more precise recognition and treatment approaches.
A study found that combining PCSK9 inhibitor alirocumab with statin rosuvastatin reduced LDL cholesterol levels by more than 50% among patients after a heart transplant. The treatment was safe and showed significant cholesterol-lowering impact, but further studies are needed for confirmation.
A quality improvement program helped reduce 'bad cholesterol' levels among military veterans, according to a preliminary presentation at the American Heart Association's Scientific Sessions 2025. The study found improvements in patient adherence and LDL-cholesterol goal attainment among participating veterans.
A study found that Black adults living in food deserts who received home-delivered groceries and dietary guidance based on the DASH eating plan had a greater reduction in blood pressure levels compared to those given a stipend to purchase groceries. The program improved cardiovascular and metabolic health outcomes, but limitations incl...
Researchers found that prasugrel may offer an advantage over ticagrelor for individuals with Type 1 or Type 2 diabetes and complex coronary disease. This is because the two medications are not interchangeable, and treatment with prasugrel may provide better benefits in preventing blood clots and adverse cardiac events.
A six-month family-based program in rural China reduced systolic blood pressure by an average of 10 mm Hg compared to non-participants. Participants implemented a low-sodium diet, exercised regularly and monitored their blood pressure using digital devices.
A new study found that a polypill combining medications for heart failure improved heart function, symptoms, and quality of life. Adults with reduced ejection fraction heart failure who took the combined medication had fewer hospitalizations and greater medication adherence than those taking individual pills.
A clinical trial led by the University of Oklahoma Health Stephenson Cancer Center has shown promising results with a new drug combination targeting metastatic colorectal cancer in patients with ATM-deficient tumors. The treatment, combining alnodesertib and irinotecan, showed substantial reductions in cancer size in these patients.
Janelia researchers have uncovered a complex interplay between the ER and lysosomes, with Lunapark stabilizing ER junctions and lysosomes regulating nearby translation. This finely tuned partnership links nutrient sensing and stress signaling to protein biogenesis.
The Blue Zones Certification Course recognizes clinicians with the knowledge to promote longevity, well-being, and health equity. Clinicians will gain expertise in applying evidence-based lifestyle habits to prevent chronic diseases.
The CliMetS initiative aims to bridge research gaps and foster cross-continental partnerships to address the threat of seabed methane seeps. Through a series of regional workshops, HKUST has united over 200 experts worldwide in mapping and quantifying these seeps.
A recent study found that team-based clinic participants perceived significant improvements in patient care, whereas technology-based clinic participants saw limited benefits. The study highlights the importance of human interaction and values-centered care in supportive cancer care.
Researchers developed a new approach combining genetic ancestry, lifestyle, and social determinants of health to identify individuals with skin cancer. The AI model achieved 89% accuracy in identifying skin cancer across all populations, with 90% accuracy for European ancestry and 81% accuracy for non-European ancestry.
Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterized by immune-mediated destruction of small intrahepatic bile ducts. Recent studies have highlighted the significance of gut microbiota dysbiosis in PBC, with reduced diversity and imbalanced flora contributing to disease progression. The gut microbiome a...
The first 2D semiconductor FPGA has successfully integrated approximately 4,000 transistors on a wafer scale, marking a significant transition for 2D electronics. The device utilizes an independently innovated integration process platform to overcome critical challenges and achieve reliable operation.
A new study found that adding a PCSK9 inhibitor to a high-intensity cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with ASCVD or diabetes. The study suggests long-term lowering with PCSK9 inhibitors can improve cardiovascular morbidity and mortality over time.
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
A new study reveals that increasing NAD⁺ levels corrects RNA splicing mistakes, improving brain function and restoring memory in animal models of Alzheimer's disease. The researchers discovered a previously unidentified pathway involving the protein EVA1C, which plays a crucial role in correcting tau-related neuronal damage.
Websites for COP conferences emit significantly more carbon than average internet pages, with a 13,000% rise in emissions between 1995 and 2024. The team's findings highlight the need to reduce digital footprint through practices such as page size limits, optimized site layouts, and renewable energy hosting.
Researchers at the University of California San Diego have developed an electronic sticker that monitors vitamin C levels using sweat from fingertips, providing a convenient and low-cost alternative to current methods. The system is battery-free and can be manufactured at a low cost, making it potentially disposable and widely accessible.
Researchers at Karlsruhe Institute of Technology discovered that enclosed water can influence its surroundings and favor binding between molecules. This finding could lead to the design of more effective drugs and new materials by leveraging the binding force of highly energetic water molecules.
The study reveals that pottery production was organized in specialized workshops near clay deposits, indicating a hierarchical organization of the El Argar society. The findings suggest a structured economy with regional and economic interactions, contradicting previous ideas about local production.
Researchers at UVA School of Medicine found that the breakdown of protective brain structures called perineuronal nets leads to social memory loss in Alzheimer's patients. Preventing the degradation of these nets may lead to new treatments to prevent or delay the disease.
The study found that having no biological offspring was linked to a higher risk of schizophrenia in both men and women. Having more than one offspring compared to one was associated with disease risks across multiple systems. Each additional offspring reduced mental and behavioral disorders by 7% and breast cancer risk by 18% for women.
A researcher is exploring how maternal diet influences offspring food choices later in life, using cells called neuropods that send signals from the intestine to the brain. The goal is to create personalized diets that are more palatable and promote healthier eating habits.
Researchers at Uppsala University have identified a new genetic technique that enables targeting of tumour cells with elevated levels of proteins driving medulloblastoma. The technique, which works like a Trojan horse, introduces an enzyme linked to SOX9 sequence, killing tumour cells.
The study identified two major factors that improve survival for children with IHG: achieving a complete surgical resection and cancer-directed adjuvant treatment. Early surgery in infants was fraught with risks of bleeding and early oncologic death, highlighting the need for strategies to minimize surgical morbidity.
Researchers from Radboud University identified eight legal risks associated with MLMs, including false income promises and pyramid scheme-like structures. Studies funded by the MLM industry often downplay these risks, creating a false impression that MLMs are safe business models.
Exercise promotes angiogenesis and lymphangiogenesis through molecular signaling pathways, enhancing vascular function and immune response. This process offers potential interventions to combat age-related decline and disease, including cardiovascular diseases, muscle atrophy, and metabolic disorders.
Researchers at the Institute of Advanced Materials aim to develop sustainable, high-performance lead-free memristors for neuromorphic computing. The MemSusPer project seeks to improve perovskite layer properties and test new materials for enhanced electrical conductivity.
A new medication called DR10624 has shown promising results in reducing high triglyceride levels by over 60% in patients with severe hypertriglyceridemia. The treatment also improved cholesterol and liver health, offering a potential alternative for managing this condition.
Researchers developed a first-of-its-kind prenatal brain model to study cerebral hemorrhages on stem cells in preterm birth. An antidote reduced brain damage, and the study identified how neural stem cells are damaged by elevated interleukin-1 levels.
Editage's expansion into Germany brings a legacy of quality, trust, and subject-area specialization to the country's respected research environment. The company aims to strengthen support for researchers in Germany, helping them communicate their discoveries effectively while preserving authenticity and integrity.
A study reveals that nearly half of the global population lives in regions facing three or more environmental problems, including polluted air, unsafe water, and biodiversity loss. The analysis provides strong evidence for urgent climate action as countries prepare to convene for COP30.
A new study finds that GLP-1 drugs tirzepatide and semaglutide reduce the risk of heart attack, stroke, and death from any cause in patients with type 2 diabetes. Both medications provide strong cardioprotective effects and may be integrated into clinical cardiovascular practice.
Researchers studied MALAT1 levels in a woman with triple-negative breast cancer, finding high levels at diagnosis and decreased while receiving treatment. Notably, levels increased at a distant metastatic site, suggesting MALAT1's role in TNBC's spread. The study informs future treatments and potential clinical trials.
A daily oral medication has been shown to lower bad cholesterol levels in people with a previous heart attack or stroke, or those at high risk for one. The study found that participants taking the medication had significant reductions in LDL-C levels and achieved guideline-recommended targets.
Two health tech companies, PolyVascular and Brainomix, won the American Heart Association's Health Tech Competition for their innovative solutions to improve cardiovascular disease and stroke patient outcomes. PolyVascular developed a minimally invasive valve to help children with congenital heart disease, while Brainomix created AI so...
Researchers have discovered how key molecules coordinate chromosome alignment in cell division. Dual inhibition of KIF18A and CENP-E selectively kills cancer cells, suggesting a new therapeutic avenue for cancer treatment. This study highlights the importance of targeting specific proteins to develop more effective anticancer therapies.
Researchers at the University of Pittsburgh have developed a skin patch test that can detect antibodies associated with COVID and flu infections. The test uses carbon nanotubes and is orders of magnitude more sensitive than existing tests.
Research finds that experiencing poverty-level family income over two decades can significantly increase the risk of dying prematurely. Rising unsecured debt is also associated with a higher risk of premature mortality, particularly when debt increases over time.
A new study suggests that chronological age should be considered when creating treatment plans for men with metastatic hormone-sensitive prostate cancer. Older patients are more likely to experience comorbid conditions and die from causes other than prostate cancer.
Researchers found that the leptin-SCD pathway fuels breast cancer growth and motility, leading to poorer recurrence-free survival. Selectively blocking SCD activity can counteract pro-tumorigenic effects driven by leptin, revealing a potential therapeutic target for obese patients.
Renowned gastroenterologist Jean-Frédéric Colombel, MD, will deliver the 31st Anatomy Lesson on November 20, exploring Mount Sinai's pioneering work in IBD prevention and treatment. His presentation aims to highlight the growing problem of immune diseases, including Crohn's disease.
A Duke University study shows that cultural norms influence gesture use, with Black and White Americans communicating differently. The research highlights the importance of considering nonverbal cues to improve understanding across racial groups.
A study found that patients with peripheral arterial disease (PAD) who also have atrial fibrillation (AFib) are at a significantly higher risk of major adverse cardiovascular events, including heart attack, stroke, and death. The presence of AFib nearly doubles the risk compared to PAD alone.
The joint research hub aims to bridge academic research and scalable infrastructure for open AI systems, with a focus on decentralised computing architectures and secure AI marketplaces. Early proof-of-concepts are expected within two years, targeting pilot applications in finance, healthcare, and smart infrastructure.
Researchers at UMC Utrecht are developing a predictive model to accurately predict disease progress in juvenile dermatomyositis. The Interferon Score aims to identify which children can safely reduce medication and which require intensified treatment.
A new UAlbany study finds that Black, Hispanic, and Native American children are significantly more likely to struggle with reading compared to white and Asian peers. The analysis of a nationally representative sample shows these gaps emerge by kindergarten.
A new method of gene editing allows for the efficient production of non-GMO, genome-edited plants without introducing foreign DNA. The technique uses Agrobacterium-mediated transient expression to enable genome editing in a transgene-free manner.
Researchers from Chung-Ang University have developed a novel AI-based approach for producing high-fidelity and defect-aware ultrasonic images, outperforming traditional techniques. This technology has the potential to revolutionize non-destructive testing in industries such as semiconductors, energy, and automotive.
A new study reveals a significant accumulation of microclots in Long COVID plasma, driven by excessive NETs production. This interaction may become pathogenic when dysregulated, suggesting underlying physiological interactions between microclots and NETs.
A new method uses uranium-lead dating and elemental mapping on dinosaur eggshells to accurately determine the age of fossil sites. This technique overcomes limitations in dating fossils themselves or associated minerals, providing a powerful tool for paleontologists to unravel mysteries about dinosaur evolution.