Researchers unveiled an integrative experimental and computational map of macromolecular transport through nuclear pore complexes. The model identifies key design features that ensure NPC efficiency and resilience, revealing new avenues for medical innovation. It also provides insight into diseases like cancer, Alzheimer's, and ALS.
Researchers develop geophysical-machine learning tool that estimates soil strength parameters using limited borehole data, enabling continuous subsurface characterization. The approach reduces the need for expensive and time-consuming drilling in challenging terrains.
A study by Politecnico di Milano reveals China's increasing demand for animal proteins sustains the consumption of natural resources in Brazil. The research shows that soybean imports to China have a significant impact on Brazilian land use, water resources, and deforestation.
The new tool helps identify gaps in open research information and provides supporting evidence for movements like the Barcelona Declaration. Crossref's Participation Reports now offer expanded features, covering over 175 million records representing a significant share of global research production.
The researchers developed a novel facet-guided metal plating strategy using Zn as the host metal, which promotes uniform metal growth and suppresses dendrite formation. The strategy improved battery stability, retaining 87.58% of its initial capacity over 900 cycles.
Research finds that commercial wind energy installations lead to a significant 3% increase in community home values after becoming operational. This effect is strongly correlated with the size of the energy project and positive impacts on school district revenues and per-pupil expenditures.
A new study reveals that AI chatbots, even when prompted to use evidence-based psychotherapy techniques, systematically violate ethical standards of practice. The research highlights the need for thoughtful implementation of AI technologies and appropriate regulation and oversight in mental health settings.
A study of 80 couples found that child- and marriage-related stressors affect self-regulation, particularly in fathers. Lower heart rate variability was associated with more difficult child behavior, with marital stress amplifying this effect.
A Northwestern University study found that Chicago parents have low intake of omega-3 fatty acids, specifically EPA and DHA, with women consuming even lower amounts. This deficiency may have direct negative effects on children's health, including preterm birth risk.
A team of researchers investigated whether blind individuals gesture like sighted people when talking about the world. The study found that visual experience influences how conceptual knowledge is expressed through gesture, with concepts relying on seeing things from a distance being harder to represent without vision. This research ha...
A new peer-reviewed analysis challenges the 2025 study on Yellowstone's wolves, finding claims of a 'world-leading' trophic cascade are unsupported. The re-analysis highlights circular reasoning and modeling assumptions violations, suggesting a more modest response to predator recovery.
A brown dwarf companion, J1446B, has been found orbiting a nearby M dwarf star, LSPM J1446+4633. The discovery uses a synergy of ground- and space-based observatories, including Subaru's IRD instrument and the Gaia mission, to determine the dynamical mass and orbital parameters of the brown dwarf with unprecedented accuracy.
A targeted intervention for repeating students resulted in increased student engagement and perseverance, particularly in the first weeks of the semester. Despite no significant improvement in overall pass rates, the intervention helped students persevere and made progress in practical exercises.
Brian Denton, professor at the University of Michigan, and Les Servi, a six-year member of INFORMS Board of Directors, have been awarded the 2025 George E. Kimball Medal for their exemplary service across various leadership roles. The award recognizes their transformative contributions to operations research and management sciences.
Researchers have published a comprehensive review on wide-temperature electrolytes for aqueous alkali metal-ion batteries, offering insights into next-generation energy storage systems. The review emphasizes the importance of interdisciplinary research to drive innovation in sustainable energy storage.
A recurring seasonal outbreak pattern of Salmonella Strathcona cases has been identified in Europe since 2011, with small tomatoes from Sicily being the likely source. The investigation found that almost all cases were genetically related, suggesting a common source and food vehicle.
A rare Seoul virus infection was reported in a German woman after visiting a private pet rat breeding facility. Laboratory tests revealed the presence of the virus in several rats from the facility, highlighting the need for better screening and hygiene practices.
A new study led by Northwestern Medicine found that botulinum toxin injections provided significant short-term relief for phantom limb pain, with an average reduction of four points on a 10-point scale. The treatment, which targets painful nerve endings around neuromas, showed promise as a potential tool to alleviate post-amputation pain.
A study found that honey bees collect similar pollen diversity regardless of surrounding agricultural land use, but with low pesticide levels. The results suggest that bees may thrive in intensively farmed landscapes by flying greater distances to find food.
Scientists discovered that the APOE4 gene blocks brain cells from using alternative energy sources as we age, significantly increasing Alzheimer's risk. This knowledge could pave the way for new treatments by targeting lipid metabolism.
A University of Helsinki study found that individuals with a religious upbringing tend to enjoy better physical health in later life and report fewer difficulties with daily activities. However, the study also suggests that childhood socioeconomic challenges may exacerbate health problems in later life.
Researchers developed a gravity-driven biochar microreactor from rattan, achieving ultrahigh flux and complete degradation of common pollutants. The system activated peroxymonosulfate through a non-radical pathway, with boundary-like defects as primary active sites.
A large international study reveals that women with a precursor condition to Parkinson's disease exhibit significantly less brain atrophy compared to men. The research suggests that estrogens may play a crucial role in protecting the brain from neurodegeneration.
A study found that vitamin D levels fell significantly during the COVID-19 pandemic, particularly among older women and urban populations. The researchers analyzed data from over 292,000 patients and discovered a 26% decrease in mean serum vitamin D levels, accompanied by a 35.2% increase in deficiency rates.
Greater arterial stiffness is associated with poorer performance in specific areas of thinking, including episodic memory and working memory. Participants with both higher arterial stiffness and elevated NfL levels showed the strongest associations with memory difficulties.
A new study by Binghamton University reveals that individuals with narcissistic, psychopathic, and Machiavellian personality traits exploit touch as a means of control in romantic relationships. They tend to have short-term, tumultuous relationships, often accompanied by violence.
Researchers develop a scalable, fluoride-free route to produce Te-terminated MXenes with superior sodium-storage properties. The one-step tellurium etching strategy merges controllable surface functionalization with green chemistry.
A new study from Wake Forest University School of Medicine found that a brief sound-based neurotechnology intervention can improve well-being by reducing symptoms of stress, anxiety, and insomnia in healthcare workers. The intervention uses acoustic neuromodulation guided by each participant's unique brainwave patterns.
A team developed an artificial ocean carbon recycling system that captures CO2 from seawater and directly converts it into succinic acid, achieving a carbon capture efficiency of 70%. The system's cost is competitive with existing state-of-the-art technologies.
A study using the independent cascade model on diverse social networks found that algorithmic outreach creates information gaps, leaving vulnerable nodes without important information. A proposed multi-objective algorithm aims to minimize this effect, resulting in a 6-10% reduction in vulnerable nodes with negligible impact on reach.
A research group has mathematically uncovered the mechanism causing crack tips to sharpen during rapid fracture of rubber, revealing that viscoelasticity is the key factor. This breakthrough contributes to improved durability and accident prevention in a wide range of viscoelastic materials.
A new study by the University of Helsinki found that a high-fat raw meat-based diet had favorable metabolic effects on dogs, while a high-carbohydrate kibble diet was associated with adverse changes. The study's lead researcher notes that more research is needed to understand the long-term health implications of these diets.
A new study reveals that the Arctic climate system is experiencing a 'pushing and triggering' mechanism, leading to an increase in extreme events such as heatwaves, sea ice loss, and ice sheet melt. The probability of these events has increased by 20-83% since 2000, with severe consequences for the region's future.
A study by UPF analyzed 6 million news-related URLs from US media shared on Facebook between 2017 and 2020. The research found that algorithm changes and user behavior contributed to the spread of biased or fake news, exacerbating ideological polarization.
Longitudinal research found that severe stress caused by family structure changes like divorce or separation during infancy triples the risk of developing psoriasis. The study, published in Journal of Investigative Dermatology, emphasizes the need to protect young children from stressful life factors.
SourceElsevier·JournalJournal of Investigative Dermatology·TypeData/statistical analysis·DateOct 21, 2025
A new international study led by Prof. Edouard Pesquet at Stockholm University uncovers the complex relationship between lignin chemistry and structure in different cell types of plants. The research highlights how this molecular diversity has enabled plants to succeed on land.
A KAIST research team found that in-home IoT data can accurately track mental health status using environmental data and smartphone-wearable data combined. Regular routines are essential for maintaining mental health, while variability in daily patterns is a key indicator of worsening mental health.
Biologists at Cold Spring Harbor Laboratory have made a significant discovery that could lead to better patient outcomes for ER+ breast cancer patients. Inhibiting the BPTF protein in mice can slow cancer metastasis and restore tumors' susceptibility to hormone therapy, offering new hope for treating resistant forms of the disease.
A new paper proposes an Aviation Sustainability Index to assess investments in cleaner technologies, helping investors distinguish between modest improvements and game-changing solutions. The approach aims to accelerate real progress toward decarbonization by rewarding companies willing to take calculated risks on breakthrough technolo...
The CPA journal was honored with the 'Great Progress Award' for its significant advancements in journal development and academic dissemination. Its impact factor has doubled to 1.5, reflecting substantial increases in academic influence and recognition.
A study by Ohio State University found that more than 15% of undergraduates and 11% of graduate students had tried nicotine pouches. Fraternity members reported the highest rates, with 41% saying they'd tried a pouch like Zyn.
Researchers have discovered a novel compound that degrades key proteins found in prostate cancer cells, blocking oncogenic androgen receptor signaling. The study found that levels of H2BNTac, p300 and CBP are elevated in prostate cancer compared to normal tissue.
The Global Pathogen Analysis Platform (GPAP) will enable low- and middle-income countries to conduct research and surveillance of infectious diseases independently. The platform aims to prevent disease outbreaks from developing into pandemics by detecting genetic sequences of potential pathogens.
Researchers used machine learning to analyze brain connectivity, environmental factors, and behavioral data from 295 older adults with cardiovascular diagnoses. The study identified key predictors of increased physical activity, including access to green spaces, social support, and executive function abilities.
Researchers at CiQUS developed a sustainable method using red light and recyclable COF catalysts to promote chemical reactions efficiently. The study highlights the potential of COFs as red-light-active heterogeneous photocatalysts, offering a significant step toward greener chemical methodologies.
Researchers developed voltage-matrix nanopore profiling to accurately classify proteins in complex mixtures based on their electrical signatures. The method reveals molecular individuality and compositional differences without labeling or modifications, holding promise for disease diagnosis and real-world bioanalytical applications.
Scientists found that breathing dusty air from the Salton Sea can alter the lung microbiome and trigger immune responses in mice. The study suggests that chronic exposure to such dust could have significant health effects, including asthma.
A new study from UT Arlington finds that fulfilling end-of-life bucket list wishes can improve well-being and strengthen family bonds. The researchers identified four consistent benefits of wish-fulfillment programs, including a lasting impact on families and caregivers.
Colorectal cancer screening modities shifted among privately insured individuals after COVID-19, with decreased colonoscopy and fecal tests, increased stool DNA tests. Differences found by sex, socioeconomic status, and metropolitan area residence.
The COAST-SCAPES project aims to co-design systemic resilience solutions for coastal landscapes by developing integrated indicators, proactive climate warning systems, and knowledge-based strategies. The project promotes the use of nature-based solutions to reduce environmental footprint and restore vulnerable coastal areas.
Ann McKee, MD, a renowned neurologist, has received a $4.2M NIH grant to investigate the long-term effects of repetitive head impacts on brain health. Her research aims to identify early-life biomarkers for dementia and Alzheimer's disease.
The Bronchiectasis and NTM Care Center Network has accepted 25 new sites, expanding access to high-quality, specialized patient care for bronchiectasis and NTM lung disease. The network aims to enhance care and improve quality of life for patients living with these conditions.
The Universitat Jaume I is participating in four joint research actions under the EDUC-WIDE project, focusing on materials science, psychology, communication, and education. The projects aim to advance sustainable water purification methods, explore social perception mechanisms, bridge communication gaps, and build an international net...
Researchers studied 18 individuals with non-degron SETBP1 variants, revealing a distinct disorder with wide range of cognitive, speech and motor impairments. Functional experiments showed that many variants disrupt DNA-binding, transcription and neuronal differentiation capacity.
Researchers create enhanced T cells with improved survival in cancer models by simultaneously modifying multiple genes using CRISPRoff and CRISPRon. The approach overcomes toxicity issues associated with traditional gene editing methods, enabling high cell survival rates and potential for treating various diseases.
PeroCycle appoints Dr Harriet Kildahl as Technical Director, leveraging her expertise in closed-loop carbon recycling. The technology converts CO2 into a valuable resource, enabling industries like steel and cement to adopt net-zero manufacturing.
The team aims to build an anonymized database representative of the whole population by collecting two vivid memories from participants. The findings will inform new ways to help people remember in more detail and understand human memories across the lifespan.
Researchers discovered that exotic roto-crystals exhibit unusual properties, including easy fragmentation and controlled defects. They found that large crystals decay into smaller units and grow until reaching a critical size, counteracting normal crystal growth.
Scientists have discovered that CENP-E plays a crucial role in stabilizing the first attachments of chromosomes to the cell's internal tracks, ensuring proper alignment during cell division. The protein stabilizes end-on attachments at the start, allowing the system to proceed correctly.
New research warns that solar radiation management through stratospheric aerosol injection (SAI) poses unforeseen challenges due to particle variability, geopolitical limitations, and economic strain. The study highlights the need for centralized coordination and careful consideration of alternative materials.