Researchers developed a two-step simulation framework to assess vibration transmitted through tracks, stations, buildings, and soil near Changsha Huanghua Airport. They found that floor responses were stronger than structural columns at the same floor, with high-speed trains causing perceptible vibrations.
A recent study published in PLOS Water revealed evidence of contamination in the tap water of Austin's Colony neighborhood, with some samples exceeding state regulatory standards for lead, arsenic, and other contaminants. The contamination appears to happen after the water is mixed together in the neighborhood's plumbing system.
Jill Mesirov brings expertise in computational biology and genomics to Sanford Burnham Prebys, aiming to advance cancer research and treatment. She will mentor next-gen computational biologists and leverage AI tools to personalize therapy.
Results of a phase 2 clinical trial show manageable side effects and clinically meaningful efficacy in patients with advanced NRG1-positive cholangiocarcinoma, doubling progression-free survival compared to standard chemotherapy. Zenocutuzumab was well-tolerated and significantly improved quality of life.
Researchers at UC Davis aim to understand how airborne nanoplastics affect human health, focusing on neurotoxicity and pollutant-adsorbed nanoplastics. They'll create a standardized method for measuring and describing the health risks of these tiny plastics.
Scientists propose a generalized Smith-Purcell effect based on programmable metasurfaces to redirect electron-induced light into chosen angles. The approach enables active tunability and broadens the range of applications for free-electron radiation, including nanoscale spectroscopy tools and compact light sources.
A team of physicists, including Giorgio Parisi and Francesco Zamponi, collaborated with AI system Claude to solve a decade-old mathematical problem in physics. They found that two different theoretical approaches to jamming lead to the same physical laws, confirming a surprising relationship.
A study analyzed daily sleep records from Fitbit devices worn by 76 undergraduates to examine longitudinal sleep patterns. The researchers found that average sleep duration increased by 8 minutes from freshman to senior year, and students with higher grades slept longer on average.
Researchers have developed novel spintronics-based probabilistic processors that accelerate complex optimisation tasks while consuming less energy. The systems achieved significant speedups and energy savings compared to conventional computers, highlighting a promising route towards faster and more energy-efficient optimisation.
A study published in PLOS One found that AI-generated impersonations of political debaters were rated as more authentic and relevant by the public than their actual responses. This raises concerns about the potential for targeted misinformation campaigns against specific public figures.
The Journal of Nuclear Medicine (JNM) has increased its impact factor from 9.1 to 9.6, ranking eighth overall among medical imaging journals. The journal saw a nearly 10% increase in citations and improved performance in various categories.
Researchers developed salt-tolerant wheat varieties with improved yield stability under sodic conditions. Key findings include proline accumulation and potassium content as primary indicators of salt tolerance.
The article explores AI-driven transformations in digital health, including a novel malaria intelligence platform and the Centers for Medicare & Medicaid Services' Landmark ACCESS program. Genuine institutional change is crucial for safe clinical AI adoption.
Scientists from the University of Chicago Pritzker School of Molecular Engineering have made significant strides in extracting lithium using an unconventional method. By applying electrochemical intercalation to a solution containing lithium and sodium ions, they were able to isolate 99% pure lithium with a high level of selectivity. T...
Research from Minot State University and the University of Illinois identified factors for making trees suitable roosts for Indiana bats. Early-successional trees can provide viable habitats in about 70 years, while late-successional trees typically take 130 years.
The research reveals how WNT signals guide embryonic cells toward specialized identities, with implications for cancer biology. Cells receive a push from WNT to start down the path toward becoming muscles, bones, organs, and connective tissue, but then receive a second layer of instruction that defines their final outcome.
A new form of CAR T cell therapy has been designed to target the CALR mutation driving MPNs, a group of chronic blood cancers. The therapy shows promising results in killing cancer cells while sparing healthy ones, and is expected to offer patients a route beyond symptom control towards deeper remissions.
Researchers found that fatty liver disease significantly increases the risk of developing replacement metastases, which are associated with poor survival rates. The study highlights the importance of integrating metabolic health into cancer care and identifies potential therapeutic targets tailored to a patient's metabolic condition.
Scientists have developed a new type of battery that harnesses ambient moisture to power IoT devices, offering a sustainable alternative to toxic materials. The batteries can be stretched without losing energy density, making them ideal for wearable monitors and medical devices.
Researchers developed a new battery management system that uses everyday charging data to detect when silicon is most vulnerable. This helps guide battery temperature control to protect it. By applying heat when silicon works harder and cooling the battery when graphite takes over, the system aims to extend EV battery life.
Researchers built a simple neural network that mimics the brain's processing of visual information, revealing a key role for inhibitory neurons in fine-tuned control. The findings suggest a revised understanding of how the brain processes and represents information.
Researchers found that deformation across the region is dominated by crustal compression, with intense strain concentrated near Siberut Island and the Sumatran Fault Zone. The study provides critical information for updating seismic hazard assessments and long-term disaster planning.
Researchers developed an app to monitor daily voice changes, which can detect early signs of exacerbations in asthma and COPD. By analyzing tone, pitch, pauses, and voice quality, the TACTICAS study found that voice deteriorates as symptoms worsen, allowing for potential treatment.
Researchers have discovered a wavelength-dependent photo-driven pathway for ammonia synthesis over lithium hydride, which decouples two conflicting reaction steps. The study provides fresh insight into mild, solar-driven nitrogen fixation and other energy-intensive catalytic processes.
A team of researchers, including Michael Fausnaugh from Texas Tech University, have identified a new planet using the Transiting Exoplanet Survey Satellite (TESS) mission. The planet, Gaia23bra b, is a super Jupiter orbiting far from its host star and offers insight into the detection methods used in astronomy.
New analysis supports the brain lag hypothesis, suggesting that some primate lineages' brain sizes overshot expectations after catching up with body size. This finding implies that large-brained primates may have evolved to form complex social groups for protection.
Researchers found that a small subset of T cells, called stem T cells, are responsible for making new T cells and replenishing them in chronic disease. Boosting these rare stem T cells overcame T cell exhaustion in chronic infection and removed overactive immune cells in type 1 diabetes.
Researchers created a detailed map of the pulvinar, a deep brain region that could help doctors precisely target brain stimulation therapies for people with drug-resistant epilepsy. The study reveals that brain regions separated by only a few millimeters connect to entirely different brain networks.
A new clinical trial led by University College London researchers found that ten weeks of cognitive rehabilitation can help people with long Covid symptoms such as brain fog achieve their goals in returning to work and hobbies. The treatment yielded benefits that lasted for at least six months for most participants.
Researchers from the University of Tokyo demonstrate that classic theory does not hold in areas with low dip angles, explaining why giant earthquakes can form in such areas. The study's findings provide a theoretical basis to extend observation efforts to previously overlooked features.
A study reveals Brazil has at least 82 non-native mollusk species, causing ecological damage and economic losses. The most comprehensive inventory in Brazil highlights the urgent need to strengthen biosecurity measures and monitor long-term impacts.
Researchers analyzed eight aspects of character portrayal in AI-generated stories, finding that AI models tend to 'play it safe' with their characters, leaving them mysterious or fully understood by the end. Human writers, on the other hand, are more willing to leave questions unanswered and let characters remain open to interpretation.
A cohort study found that upper secondary school settings are associated with mental health trajectories in adolescents, suggesting a link between peer environments and risk of mental disorders. The study's findings highlight the importance of considering environmental factors in understanding adolescent mental health.
A team of scientists found that a small subset of T cells called stem T cells are responsible for making new T cells and replenishing them in chronic disease. These rare stem T cells express the protein LEF1, which is key to their persistence. Boosting LEF1-positive cells overcame T cell exhaustion in chronic infection, while removing ...
A University of Otago study analyzing 15,000 head acceleration events from community rugby players found significant sex and size biases in injury risk predictions using a one-size-fits-all approach.
A study by Rutgers researcher Chien-Chung Huang found that compulsive smartphone habits in older adults can deepen depression. Limited social participation and smartphone addiction were strong predictors of depression, while phone use supporting relationships and interactions was protective.
Casdatifan, a next-generation HIF-2α inhibitor, demonstrates effectiveness in treating metastatic clear cell renal cell carcinoma with manageable side effects and promising signs of efficacy.
A Stanford-led study found that pollution is causing fish hybrids to form in a Mexican river, threatening species diversity. The researchers analyzed water and fish samples from four rivers and found that those with higher levels of chemicals and heavy metals had more hybridized swordtail fish.
Researchers at McMaster University have developed a cancer immunotherapy strategy targeting glioblastoma, one of the most aggressive brain tumours. The therapy, using Chimeric Antigen Receptor T-cell therapy, recognizes and attacks both the tumour cells and immune cells that support their growth, offering a new approach to treatment.
Researchers at KAIST have developed a prodrug that selectively activates in the brain of patients with Alzheimer's disease, reducing reactive oxygen species and preventing amyloid beta aggregation. This approach shows promise for next-generation dementia treatment.
Researchers at Stanford Medicine have developed a new technique that enables the precise location of cancer-fighting antibodies in human tumors. The technique, known as single-cell spatial pharmacobiology, allows for detailed imaging of antibody binding to specific cells within the tumor microenvironment.
Researchers developed a strategy to attack glioblastoma on two fronts by targeting the tumour and its immune support system. In preclinical models, the therapy eliminated detectable tumours and led to long-term disease-free survival.
Scientists have discovered a 518-million-year-old fossil named Urokodia, which shows the earliest evidence of spiders' fangs. The fossils revealed two pincer-like limbs emerging behind the eyes, marking the beginning of chelicerae. This discovery sheds light on the origin of spider bites and book gills in the Chelicerate family.
The University of Rochester has launched the Virtual Institute for the Physics of Agentic Intelligence (VIPAI) with a $4.2 million grant from the John Templeton Foundation. Researchers aim to investigate whether artificial intelligence systems can exhibit autonomous agency and goals, like living beings.
A new study published in PLOS One found that slower maternal vocal responses at 12 months may predict later childhood behavior disorders such as ADHD. The study analyzed data from 158 mother-infant pairs and found associations between slow maternal responses and increased odds of psychiatric diagnoses by age seven.
Researchers created nanozyme proximity labeling (NPL) to visualize protein interactions and trafficking pathways of nanoparticles in live cells. The technique provides a high-resolution, in situ snapshot of how surface modifications influence nanoparticle destinations.
Researchers found that patients with Parkinson's disease showing little to no Lewy bodies despite long-standing, clinically advanced disease. The study provides new insight into the relationship between clinical symptoms and neuropathological progression.
Researchers have identified a key marker of highly aggressive and treatment-resistant colorectal cancer cells. Combining chemotherapy with TROP2-targeted therapies significantly improves effectiveness in laboratory trials.
Researchers found that animal models with Alzheimer’s-related brain changes developed problems with cognitive flexibility months before showing signs of memory impairment. The study suggests that Alzheimer’s disease may affect neural circuits involved in executive function and adaptability before causing noticeable memory problems.
The American Heart Association has named its new volunteer leaders for the 2026-27 fiscal year, including Manesh R. Patel as volunteer president and Lee A. Shapiro as chairperson. Patel is a physician/scientist specializing in interventional cardiology, while Shapiro is a financial expert in health technology.
New essay highlights policy priorities to safeguard urban forests, essential infrastructure for climate emergency resilience and equity. The authors emphasize the vital role of these ecosystems in promoting biodiversity and improving public health.
The University of Alicante is part of the international team producing the World Ocean Assessment, the most ambitious report on the current state of seas and oceans. The assessment highlights the urgent need to protect marine ecosystems, which are essential for human well-being and face unprecedented challenges from climate change, pol...
A new study by University of Wisconsin-Madison researchers suggests that reaching net-zero emissions by mid-century will substantially improve public health in the US. The study found that climate strategies relying less on carbon dioxide removal lead to better air quality and lower premature deaths.
A Thai study found that shelter dogs in more crowded conditions tend to have disrupted gut microbiomes compared to those with more space. The research analyzed stress, metabolism, and fecal microbiota in dogs, providing insights into the impact of shelter conditions on animal health.
Researchers call for hearing tests to be a standard part of diabetes care due to its high prevalence among adults with type 2 diabetes. A systematic review of 29 studies found that hearing loss is a significant yet under-recognised complication, affecting daily conversations and quality of life.
A new skill-based reinforcement learning approach refines hierarchical policy through dynamical skill refinement, achieving higher asymptotic performance and stable improvement compared to SOTA methods. The unified optimization objective guarantees performance improvement in TA-MDP and optimizes the original MDP's performance lower bound.
Researchers developed a dye-sensitized core-shell structure using Yb3+ as an 'energy relay' to achieve synergistic cascade energy transfer between ICG and the Er3+ core under 808 nm excitation. The system enhances luminescence intensity by nearly 2000-fold, providing superior performance for high-resolution imaging in deep tissues.
A new evolutionary theory proposes that asexual parasites can temporarily infect a wider range of hosts as harmful genetic mutations build up. This process, known as Ratchet-Driven Generalism, may make the parasite less specialized and more adaptable. However, it may also ultimately reduce fitness and increase extinction risk.
A new study co-led by Aston University researchers has found no association between prenatal paracetamol exposure and the risk of autism spectrum disorder (ASD) or attention-deficit hyperactivity disorder (ADHD). The research analyzed electronic medical records from over 708,000 mother-child pairs in Hong Kong spanning two decades.
A new study from the University of Copenhagen found that people diagnosed with ADHD or autism in recent years have a lower genetic predisposition than those diagnosed earlier. The study suggests that today's diagnoses encompass a broader group of individuals and milder symptom profiles. This shift is attributed to changes in diagnostic...