Research on targeted radioactive gold nanoparticles shows promise against aggressive brain tumors. Ultra-high-resolution PET scanners provide detailed views of mouse brains. New imaging tracers target key drivers of prostate cancer growth.
Researchers found a strong association between gut microbiome composition and bone health in patients with primary hyperparathyroidism. Bifidobacterium longum was identified as a key microbial driver of bone loss through immune-mediated mechanisms.
The University of Oklahoma is establishing the Oklahoma Center of ImmunoEngineering with an $11.5 million NIH award. The center will integrate wet lab science and data science to accelerate disease research. Four early-career faculty members are selected as research project leaders, and the center offers training workshops, seminars an...
Researchers found that people are less likely to notice negative spoken words than neutral ones when focused on a visual task. The study suggests the brain's unconscious mind filters out harmful information to prevent distractions and mental fatigue.
Researchers at Shanghai Jiao Tong University developed a novel solid-state 3D printing process that produces ultra-tough aluminum components. The screw extrusion-plasticizing friction stir deposition (SEFSD) method bypasses the melting phase, resulting in homogeneous structures with exceptional strength and ductility.
A new study found that even as oak trees continue to photosynthesize late into the year, their growth stops by mid-summer. This decoupling between photosynthesis and growth suggests that increased carbon uptake may not translate to greater wood production, reducing long-term carbon storage in forests.
Engineers at University of Texas at Austin developed a jacket that collects moisture and funnels it to detachable harvesting units, producing 400-900ml of drinkable water per day. The fabric shows a three- to 10-fold improvement at scale, making it a significant advancement in atmospheric water harvesting.
Researchers found that pramipexole, a Parkinson's disease medication, improved symptoms of anhedonia in patients with treatment-resistant depression. The therapy was associated with positive effects on the brain's reward system and increased physical activity.
A new study reveals that mountainous landscapes can store significantly more carbon in the soil than previously believed. Researchers found that soils in landslides can be up to 5 meters deep and contain twice as much carbon as predicted by previous global models.
A comprehensive study has identified 100 species with documented migratory behaviour in dragonflies, while another 85 are likely to migrate. Dragonfly migrations reveal an unseen world above our heads, with insects undertaking journeys that can rival those of birds, and provide insights into ecosystem changes and climate shifts.
A new study found that replacing beef with salmon once a week can save up to 28% of carbon emissions, equivalent to a return flight to Marrakech. The researchers suggest simple diet changes could contribute to national targets of reduced carbon emissions.
A $4 million NIH grant will help UC Davis researchers develop and test bioengineered grafts infused with ligands to treat neurogenic bladders in children. The grafts, designed to grow their own blood supply, have the potential to reduce complications after standard bladder augmentation surgery.
Elsevier has launched its Ebola Information Center, providing free access to critical clinical and research information to support the global response to the outbreak. The center combines evidence-based clinical guidance, peer-reviewed research, and AI-assisted tools to aid in rapid evidence discovery and response coordination.
NYU Abu Dhabi and Cleveland Clinic Abu Dhabi researchers have developed an injectable device that can control nerve activity without surgery or wires. The device delivers controlled electrical signals that influence how nerves behave, allowing for precise control and minimal invasiveness. This new technology complements existing treatm...
Researchers propose a new framework to model critical infrastructure resilience, focusing on AI-integrated infrastructures. The study identifies key performance indicators (R-KPIs) and provides a ten-step operational framework for analysts to assess resilience.
Researchers from Sun Yat-sen University discover a novel mechanism by which tsRNA-Gly promotes hepatocyte regeneration in ACLF. The study reveals that tsRNA-Gly activates GRHL1 and upregulates CCND1, driving liver regeneration.
A new anti-inflammatory molecule has shown promising results in protecting neurons and delaying disease progression in mice with Parkinson's disease. The study, published in Neuropharmacology, found that the Ac2-26 peptide mitigated neuroinflammation and protected against cell death.
Researchers developed a new approach using NASA's PACE satellite data to observe fall colors, producing detailed leaf color maps and tracking changes. The study improves traditional greenness indices by identifying precise markers of the end of the growing season.
A new study found that horse owners' psychological characteristics, including attachment styles and personality traits, shape how frequently they ride, train, and spend quality time with their horses. Owners who spent more time with their horses tended to be more emotionally connected, while those with higher avoidant attachment styles...
A large meta-analysis has consistently shown that social inequality, such as poverty and racism, accelerates biological aging measured by epigenetic clocks. Newer biological aging measures are most sensitive to social conditions, with second- and third-generation clocks showing stronger associations with socioeconomic conditions.
An international team published a white paper on embryonic models based on stem cells, proposing guidelines for research and regulation. These models can mimic early human development stages, potentially aiding in understanding infertility conditions.
A novel operator learning framework tackles the ill-posedness in inverse thermal problems by employing two synergistic deep learning components. The framework accurately estimates spatial material properties and filters high-frequency noise to project the final-state thermal field back to its initial distribution.
The study focuses on the Lamm-Riviere system, a fourth-order geometric elliptic system including both extrinsic and intrinsic biharmonic maps into manifolds. Researchers investigated the inhomogeneous Lamm-Rivireè system and proved the angular energy identity for this system.
Researchers have developed a new theory that enables the description and simulation of non-reciprocal interactions, which are essential for studying complex systems like flocks and swarms. By introducing auxiliary degrees of freedom, physicists can now accurately model these systems using established methods.
The ASCEND project aims to develop next-generation catalysts using AI, simulations, and nanotechnology. The five-year initiative accelerates scientific experimentation and enables more sustainable chemical processes.
The book 'Human Identities in the Archaeological Record' reconstructs past identities from evidence like skeletons, belongings, and material culture. Researchers investigate how people ate, grew up, and were affected by disease and inequality.
The Journal of Research on Research aims to support evidence-informed change in research systems through a unique dual role as both a publisher and researcher. It will occupy a dual role: publish and conduct research on research, providing access to data on publishing processes across its portfolio.
A University of Birmingham scientist creates a 'mini universe' with ultracold atoms to test ideas in quantum cosmology and gravity. The experiment demonstrates that time can emerge from changes within a quantum system, revealing a version of time known as 'entropic time', which flows consistently and orders events.
Researchers reconstructed millipede evolution history, tracing origins to nearly 460 million years ago. They also discovered that one group of millipedes may have developed chemical defenses 260 million years ago.
Research finds that advanced maternal age reduces autophagy in embryos from aged female mice, leading to impaired embryonic development. Supplementation with Rapamycin improves early embryonic development by regulating metabolic pathways.
A new model developed by KAIST reveals that a shortage of agricultural workforce can limit farmland utilization in most regions, posing a significant risk to future food security. The study's findings suggest that sustainable development models and migration policies are crucial to addressing this issue.
Researchers at the University of Zurich have identified 10 biomarkers in saliva that can detect acute sleep deprivation. The study uses machine-learning methods to analyze metabolic changes in saliva, providing a new milestone for forensic research.
A population-based study found that radical nephroureterectomy was associated with better overall and cancer-specific survival compared to kidney-sparing surgery. Tumor stage, size, lymph node dissection status, and patient-specific factors play a crucial role in individualized surgical planning.
A cross-sectional study found that colorectal cancer screening participation increased after an organized population screening program, but socioeconomic disparities remained. Younger age groups, single households, and lower-income individuals still lag behind in screening uptake.
A research team led by Prof. Yongtaek Hong developed a high-performance transparent organic light-emitting diode (OLED) incorporating highly conductive transparent metal mesh top electrodes fabricated using a selective metal deposition technique. The electrodes achieved high optical transparency of 93-99% and low sheet resistance, maki...
A recent study published in JAMA Network Open followed 264 mother-infant pairs to assess the anatomy of the upper lip frenulum and its relation to breastfeeding difficulties. The research found no association between the anatomical characteristics of the upper lip frenulum and breastfeeding problems.
The new section in JMIR Neurotechnology focuses on the responsible and ethical use of neurotechnology. Submissions welcome for original research, case series, theoretical viewpoints, and data-driven analyses on ethics and policy in neurotechnology.
A new study reveals that written exposure therapy can significantly reduce PTSD symptoms, comparable to intensive treatments. The narrative writing process allows patients to confront memories, fostering a sense of control over their experiences.
JMIR Publications has partnered with MetaROR to advance open science, elevate peer review quality, and recognize reviewers' contributions. The partnership integrates MetaROR's publish-review-curate platform with JMIRx overlay journals.
Insilico Medicine is revolutionizing preclinical drug development through its AI and automation platform, reaching PCC nomination in just 12-18 months. The company has nominated 31 PCCs since 2021, with 13 receiving IND approval or clearance.
Researchers found that disruptions in specialized extracellular structures surrounding cerebellar neurons alter neuronal activity across brain circuits involved in social behavior. Mice without these structures showed clear impairments in social interaction and decreased interest in unfamiliar mice. The study suggests a previously unkn...
A study identified molecular anchors on gut phages that enable them to attach to human cells and remain intact. The findings suggest that these proteins are evolutionarily advantageous strategies driven by modular phage surface proteins.
Researchers developed a metal-free carbon monoxide prodrug that significantly reduced metastatic tumor growth in pancreatic and triple-negative breast cancer models without signs of toxicity. The prodrug, CO-116, works by disrupting a signaling pathway that promotes cancer cell migration and metastasis.
Rockefeller University Press has partnered with Cashmere to enable safe and transparent AI inference use of its journals, protecting authors' work while providing visibility and revenue transparency. The partnership uses Cashmere's infrastructure suite to manage AI-powered research applications.
A study by Okayama University researchers revealed that SARS-CoV-2 antibody levels can assess infection history, symptom severity, and cognitive complications in long COVID. The findings suggest that declining S-antibody levels may indicate a greater risk of neurological complications.
The study synthesizes recent advances in single-cell and spatial transcriptomics to identify tumor-enriched cell subsets closely related to prognosis and treatment response. The review introduces the
A study found that regularly assessing gastric residual volume in critically ill children being enterally fed significantly improved nutritional achievement at 72 hours. Not routine assessments every 6 hours had similar results, demonstrating noninferiority.
Researchers have developed a catalyst material that harnesses the energy of a single photon to reduce carbon dioxide and oxidize organic waste simultaneously. The process achieves high efficiencies of approximately 93% for CO2-to-formate conversion and around 95% for biomass oxidation, showcasing efficient utilization of photon energy.
A new study offers a framework for transdisciplinary urban science by combining particularising and generalising perspectives to inform policy decisions. The research emphasizes the need for constant interaction between researchers, publics, and policymakers to chart sustainable pathways for cities.
Researchers discover recurrent COPA mutations driving intestinal tumorigenesis through an independent route. These mutations activate the Wnt pathway in a way that bypasses essential amplifiers, leading to cancer progression.
Researchers create a hydrogel-based oral formulation that coats the esophageal lining and releases antibodies like infliximab to treat inflammatory conditions. The formulation reduces side effects by temporarily loosening cell-cell junctions, allowing larger molecules to pass through.
The system uses two AI agents to comb through publicly available data and conduct life cycle assessments, achieving an average error rate of 5%-19% similar to expert-led LCAs. The team also developed a new method to bypass detailed data collection and estimate carbon footprints for unknown devices using 'nearest-neighbors' approach.
Researchers found Escherichia albertii bacteria in 77% of water samples and 56% of wild raccoons, suggesting a pathway for transmission from wildlife to humans. The study's findings emphasize the need for a 'One Health' approach to address zoonotic diseases.
A joint study by HKU and LSE reveals global migration has risen sharply from 13 million people per year in 2000 to 35 million in 2023. The dataset, built using deep learning, provides a more detailed and dynamic picture of global movement.
Professor Geim's talk revealed how curiosity-driven research led to the discovery of stable, single-atom-thin sheets of carbon, a breakthrough that earned him the 2010 Nobel Prize in Physics. His current work focuses on expanding this atomic toolkit to create new materials with unique properties.
A new study reveals that Antarctic glaciers are speeding up and moving towards the ocean due to meltwater draining from their surface to their base. This process, known as hydrofracturing, reduces friction and accelerates glacier movement.
The University of Hong Kong study found that effective use of hearing aids is associated with a lower risk of probable dementia among older adults with hearing loss. The association appeared stronger in middle-income countries where hearing aid adoption was lower.
Researchers analyzed high-speed camera footage of skilled soccer players performing the scissors feint, revealing distinct movement characteristics that differ from less-skilled players. These include active distance regulation, strategic modulation of relative speed and efficient feint execution.
A study of 90 Japanese esports players found 43.3% had poor subjective sleep quality, with later bedtimes and shorter sleep times common among pros. Early-morning gaming was linked to poor sleep quality, highlighting the need for sleep support tailored to competitive status.
Professor Yao's research on two-dimensional materials and their heterostructures has opened up an important direction for future optoelectronic devices. He received the Certificate of Merit at the Fourth National Award for Excellence in Innovation, recognizing his academic influence in this frontier field.