Deep brain stimulation (DBS) can remodel white matter pathways in the brain and alter communication across large-scale neural networks. The therapy helps patients recover from severe depression by increasing fractional anisotropy and myelination within specific pathways, suggesting a previously unrecognized mechanism.
Over two decades, Biscayne Bay has become warmer, saltier, and more acidic due to climate change, threatening South Florida ecosystems. The study analyzed water quality observations collected between 2001 and 2021, finding significant increases in salinity and declining pH levels.
Research on deer mice reveals a unique gene family, Phf8y, that acquired from the X chromosome and duplicated itself on the Y chromosome. This discovery provides insights into how the Y chromosome defends against decay and maintains fertility in males.
Andrew Yang's research has reshaped scientific understanding of the blood-brain barrier and its role in brain health and disease. His latest study reveals new potential treatment targets for neurological diseases, normal aging, and sleep.
Researchers at Rice University have developed a noninvasive method to track the expression of specific genes in living brain tissue, enabling real-time monitoring of gene activity. The tool, called In-vivo Tracking of Active Transcription (INTACT), uses engineered reporter molecules and sensors to detect target mRNA in the bloodstream.
Researchers found coordinated brain activity linked to social behavior begins seconds before movement starts in zebrafish. The pallium plays a key role in generating social drive, with stronger neural signatures predicting more socially engaged individuals.
The LEGO Foundation Fellowship will support up to 10 researchers pursuing ambitious work on how children thrive in crisis and conflict settings, neurodivergent children, and AI-enabled learning. The fellowship aims to deepen understanding of what helps children learn, grow, and thrive.
A new study from Northwestern University reveals American voters are more accepting of gay candidates than ever before, but acceptance is conditional and varies by political party. Republican voters continue to penalize candidates for being gay, while Democratic voters punish those who look or sound slightly gender nonconforming.
The study found that adjuvant nivolumab did not improve disease-free survival in patients with resected non–small cell lung cancer. The treatment was also not effective in sensitizing EGFR and ALK alterations.
The Healthcare Infection Prevention Advisory Group (HIPAG) aims to address gaps in infection prevention expertise and support evidence-based practices. HIPAG will provide national expertise on antimicrobial resistance, emerging infectious disease threats, and frontline healthcare operations.
Researchers analyzed tumor samples from over a thousand patients and found that TP53 gene mutations can worsen prognosis and reduce effectiveness of targeted therapies. The study suggests incorporating genetic testing into public health services to guide personalized treatment choices.
Current evidence suggests P2Y2 signaling is associated with multiple cancer-related processes, including cell proliferation, migration, and EMT. The receptor has also been linked to intracellular signaling pathways such as EGFR, PI3K–AKT, and MAPK.
A new PET radiotracer can effectively image overactive adrenal glands, allowing for a non-invasive approach to diagnose primary aldosteronism. This could enable physicians to tailor treatment plans for patients with this condition.
Adding fovinaciclib to first-line aromatase inhibitor therapy confers significant progression-free survival benefits and consistent improvements in efficacy outcomes. The treatment also has manageable safety profiles with no negative impact on quality of life.
A new study by the Max Planck Institute for Chemistry finds that accelerating renewable energy expansion can effectively close the energy supply gap while providing climate change mitigation benefits and improving public health. This creates substantial societal and economic benefits, outweighing the costs of renewable energy expansion.
A recent study revealed that the bacterial pathogen Flavobacterium columnare remodels its epigenetic landscape during prolonged starvation, rather than altering its DNA sequence. This finding suggests a novel survival strategy for the bacterium and could have direct implications for aquaculture disease control.
A recent study by Karolinska Institutet researchers found that semantic knowledge plays a vital role in human innovation, enabling individuals to create new connections between objects and ideas. The study showed that groups with access to both semantic knowledge and social learning produced more unique innovations than those with only...
A recent study found that hormone therapy use among US women has steadily declined from 4.4% in 2007 to 1.7% in 2023, despite its proven benefits for symptom relief and quality of life. The majority of women who could benefit from hormone therapy are not receiving it due to misconceptions about risks and limited training among clinicians.
Researchers at Stevens Institute of Technology discover that mature gut cells can revert to cancer-driving stem cells, explaining why colorectal cancers are resistant to treatment. This finding suggests pathways for effective therapies and sheds light on the complex cellular environment of the intestines.
The American Heart Association and Houston Texans trained nearly 100 youth sports coaches in CPR and AED use, gaining hands-on experience to recognize cardiac arrest. Without immediate CPR, more than 90% of people who experience cardiac arrest outside a hospital do not survive.
Researchers used magnetic particle imaging to track cell therapy injections in mice, finding that it can visualize therapeutic cells as they inject them. The technique shows promise for developing more effective treatments for certain cancers, autoimmune diseases like MS, and neurological conditions.
A research project led by University of Tennessee at Knoxville associate professor Candace Brakewood aims to evaluate the impact of congestion pricing on public transit systems. The study will focus on New York City's recent implementation, analyzing how it increased transit ridership across subway, bus, and regional rail systems.
Researchers created the first 3D map of heart's electrical wiring in Tetralogy of Fallot, a common congenital heart problem. The map reveals anatomical features that may explain heart conduction disorders in this condition.
The symposium brought together a diverse pool of medical researchers to share groundbreaking studies on emerging technologies in medicine. The event highlighted pioneering approaches that are transforming patient outcomes, showcasing how Hackensack Meridian Health is paving the way for novel therapies.
Researchers at USC Dornsife College of Letters, Arts and Sciences have developed a new framework to understand how marine microbes grow, compete, and recycle carbon around the globe. The study identifies eight metabolic groups that help explain how microbial communities vary across the ocean.
A new web tool, FishCast, helps forecast drought impacts on trout populations and support fisheries and water management in Montana's blue-ribbon rivers. The tool integrates weather information, historic trout population data, and streamflow records to predict drought risk and trout population trends.
Weight loss after bariatric surgery is associated with better ability to cope with daily household tasks such as cleaning and grocery shopping. The study also found that maintaining weight loss for long periods results in improved functionality and independence. Patients who regained lost weight experienced poorer outcomes over time.
The study provides a detailed, cross-species view of how tumor-associated dendritic cells are organized and altered in cancer. It identified over 30 distinct dendritic cell subsets and functional states within tumors, with many populations conserved between mice and humans.
Researchers found that HIV-associated protein gp120 increases nerve receptor activity, leading to increased pain sensitivity. Targeting this mechanism with drugs or genetic approaches may alleviate chronic pain associated with HIV, and could also treat other conditions.
The Society of Interventional Radiology has published new practice guidance for the use of prostatic artery embolization (PAE) to treat enlarged prostate. PAE is a minimally invasive treatment that offers men an effective alternative to conventional surgical treatments.
A new study led by Professor Dr. Anne Burmeister found that individuals seeking advice are more likely to reach out when they learn about the benefits for both parties involved, resulting in a 40% increase in contacts and high-quality advice received.
A University of Reading research team is developing a potential treatment for chronic nerve pain using tiny stem cell particles. The RESOLVE project aims to reduce inflammation and reset the processes that drive long-lasting pain, offering a different approach to current treatments.
Proteins lose their hydration shell when environment becomes more acidic, a process that had remained unanswered for 50 years. Direct observation of individual water molecules reveals clear rules: certain amino acids bind or release water, leading to stable inner core regardless of pH level.
A remotely operated AI algorithm has identified the critical view of safety (CVS) in pediatric patients, detecting when all safety criteria were met and issuing real-time alerts. This approach combines AI with teleconferencing for potential new intraoperative guidance without requiring specialized hardware.
Researchers discovered a novel gene BM-SZ that regulates sorghum's cuticular wax accumulation and drought tolerance. The study highlights the gene's essential role in epicuticular wax formation during sorghum evolution.
Researchers at KAIST have developed a new catalyst design technology that can improve the efficiency of key reactions in batteries and fuel cells. By adjusting the electrical environment around the catalyst, they were able to increase the desired reaction by 52%, leading to improved performance, lifespan, and stability.
A new study found that polyopioid use, depression, and persistent pain are strong predictors of suicidal ideation in SCI patients. Researchers urge healthcare providers to screen for suicidal ideation when prescribing multiple opioids or showing signs of misuse.
Applying a magnetic field during catalyst synthesis triples the ammonia yield, making catalytically active sites more accessible. The study demonstrates a scalable strategy for developing next-generation electrocatalysts for efficient and sustainable chemical production.
Researchers decode signaling pathway of atypical chemokine receptor ACKR4, revealing its role in internalizing and degrading unnecessary chemokines. This mechanism helps guide immune cells and regulate inflammation, with potential implications for cancer treatment.
Dr. Martin G. Pomper has been awarded the 2026 Benedict Cassen Prize for his outstanding contributions to nuclear medicine, particularly in the development of PSMA-targeted agents. His work has led to significant advances in cancer diagnosis and treatment, including the creation of commercial PSMA-targeted PET agents.
A recent study by CISPA Helmholtz Center for Information Security examines how users perceive AI labels and their impact on information credibility. The study found that while AI labels can reduce belief in false content, they also trigger skepticism and shape trust more than the content itself.
Research suggests using Chinese rare minnow embryos as an alternative to conventional acute toxicity tests with juvenile fish, reducing animal use and avoiding redundant testing. The study found that embryo-based tests can provide a more sensitive endpoint than lethality alone, highlighting the importance of endpoint selection.
A University of Reading study found that pressure on women to have a natural birth leads to shame and self-blame when expectations are not met. Women reported feeling they had failed as mothers due to medical intervention or complications, highlighting the need for reform in antenatal education.
A randomized clinical trial found that an app-facilitated palliative care intervention maintained health-related quality of life and reduced acute care use. This digital self-management approach also boosted patient self-efficacy.
A new PET radiotracer, 18F-GP1 PET/CT, accurately detects deep vein thrombosis in the legs and reveals lung clot migration. The approach may support faster diagnosis and improve patient care by detecting disease early.
A cohort study found that introducing immunity in US nursing homes was associated with lower overall staffing and staff-to-resident time. During the COVID-19 pandemic, many states adopted immunity from tort liability for harms to nursing home residents.
LGBTQ+ adults over 50 face disparities in health care, mental health, and social connections compared to non-LGBTQ+ peers. They are more likely to experience discrimination and feel isolated from others.
The new feature combines AI-Assisted Data Entry and AI-Assisted CV Import capabilities, allowing researchers and administrators to quickly generate structured records from CVs and unstructured documents. Human-in-the-loop safeguards ensure explicit user review and confirmation before data is applied to a profile.
Researchers developed a new method to raise germ-free zebrafish using gamma irradiation, enabling long-term studies of host-microbe interactions. This approach revealed significant differences between germ-free and intact zebrafish, suggesting conserved roles for microbiomes in immunity and metabolism across species.
Researchers found that traumatic occlusion combined with periodontitis leads to significant bone loss due to upregulated inflammatory pathways. The study suggests that excessive bite force does not directly cause damage but exacerbates existing dysregulation, making clinical applications of occlusal adjustment in treatment more relevant.
A novel solar-thermal desalination process produces fresh water in an energy-efficient way, eliminating brine and chemical additives. The technology leverages the 'coffee ring' effect to extract salts from seawater, producing nearly 100% of the salts in solid form.
Researchers discovered curcumin's ability to stabilize microscopic ceramic parts by physically screening stray light and neutralizing erratic energy sparks. This approach enables the production of complex, ultra-lightweight components for advanced technologies.
Researchers developed an AI-enabled method, RivDepth, to map river depth in complex environments. The model combines satellite spectral information with suspended sediment concentration proxies, capturing water depth and reflectance patterns with high accuracy.
Researchers developed a nanocomposite coating that improves stainless steel's resistance to highly acidic conditions, offering a potential solution for industries with metal equipment exposed to aggressive chemicals. The coating delivered up to 98.2% corrosion inhibition efficiency and remained stable over seven days of immersion.
Dr. Owen Carmichael received the James W. and Neil Ann Parks Professorship for Dementia Research, Prevention and Treatment at Pennington Biomedical. His work focuses on developing advanced biomedical imaging techniques to better understand Alzheimer's disease and brain aging.
Research on box jellyfish reveals complex reproductive traits and strategies, shedding light on their life cycles and ecological role. Understanding these processes can improve predictions of jellyfish occurrences and inform management efforts.
A recent study published in Depression and Anxiety found that moderate-to-vigorous physical activity and sufficient sleep are crucial for protecting mental health in middle age. Replacing sedentary behavior with light activity produced smaller benefits compared to moderate-to-vigorous physical activity, highlighting the importance of i...
A qualitative study in Norway finds that seashore play is key to fostering emergent ocean literacy in early childhood education for sustainability. The research highlights the importance of collaborative exploration, relationships, and play in supporting environmental awareness.
A UNIGE team studied the evolutionary history of plant mechanisms that protect against UV-B radiation in Marchantia polymorpha. They found that while the core mechanism is conserved, regulatory proteins play different roles in ancestral and modern plants, influencing their tolerance to light stress.
The research team developed a technology that directly forms a junction structure within a 2D semiconductor using a laser to enhance photodetection performance. The resulting energy barrier rapidly separates the positively and negatively charged carriers generated by light, suppressing their recombination.