Researchers analyzed brain tissue from MSA patients and found that the immune cells known as microglia appear to be exhausted or dysfunctional in later stages of the disease. The study suggests that an overactive immune system may contribute to the development of MSA, providing a potential target for future treatment.
A reanalysis of 14 years of Hubble data suggests that Europa's water vapor plumes may not exist as previously thought. The study, led by SwRI scientists, found reduced confidence in the original findings, and improved information on neutral hydrogen atom emissions from Europa's surface.
Researchers developed an oral spray using polyphenols from molasses to neutralize dog breath and harmful bacteria. The spray reduced odor-producing compounds and pathogenic bacteria in dogs' mouths after a single application.
A common genetic alteration in prostate cancers enables tumors to bypass dependence on male hormones and instead rely on cortisol, leading to treatment resistance. Combination therapy targeting both androgen signaling and cortisol activity can suppress tumor growth and extend survival.
Researchers at Mizzou's Molecular Imaging and Theranostics Center developed an automated approach to producing the prostate cancer treatment. The new method produces CTT1403 in just 38 minutes, compared to six hours with traditional methods, using a commercially available automated synthesis system.
The journal MedScience aims to integrate cutting-edge insights across medical sciences, focusing on emerging fields like cell therapy, AI-driven drug discovery, and precision medicine. This new platform serves as a dynamic hub for international academic exchange and translation of scientific breakthroughs into clinical practice.
A University of East London academic has published a book exploring how businesses can use AI, blockchain, and data analytics to become more adaptable and innovative. The publication argues that digital transformation is about people, strategy, and responsible leadership, not just technology.
A new study found that increased immigration enforcement by ICE led to significant declines in employment among immigrant women in regulated childcare settings, with a shift towards private household childcare. This may negatively impact childcare quality and stability, as well as labor markets for lower- and middle-income parents.
Aqueous zinc-ion batteries face complex interfacial challenges due to dendrite growth, parasitic hydrogen evolution, corrosion, and SEI instability. Advanced characterization techniques reveal chemical composition, solvation structures, and SEI evolution at buried interfaces.
A new study found that AI-induced job insecurity significantly increases employee burnout in emerging economies, but psychological safety and confidence in working with AI systems can buffer workers from negative emotional impacts.
A global study led by George Mason University found that balanced energy and protein supplements improve birth weights and reduce high-risk newborns in low- and middle-income countries. The research adds to the evidence that improving maternal nutrition during pregnancy may be a key intervention to improve birth outcomes.
A case-control study found that amateur-level soccer heading is associated with increased blood biomarkers of neural damage, including dose-response relationships. The findings suggest that even low-impact heading may acutely affect neural integrity.
A research study, COACH trial, is testing different ways to help children and families improve their health through lifestyle changes delivered by primary care clinics. The study aims to assess the effectiveness of personalized nutrition counseling, community resources, and online interactive lessons on weight management.
Researchers at Arizona State University measured air temperatures downwind and upwind of data centers in Phoenix, finding a significant impact on surrounding neighborhoods. Temperatures downwind averaged 1.3-1.6 degrees warmer than upwind, with detectable effects up to five city blocks away.
International experts in laboratory medicine, osteoporosis, and chronic kidney disease recommend ending routine reporting of albumin-adjusted ('corrected') calcium. The practice may misclassify patients and compromise care due to unreliable correction formulas and variability in local measurements.
A Peking University study found that population ageing, not just air pollution, contributes to rising dementia deaths in China. Lower PM2.5 levels have brought health benefits, but the rapid growth of China's older population offsets progress.
Surgical patients with mental health and/or substance use disorders who receive music therapy have a 41.8% longer length of stay compared to those without music therapy. They also exhibit increased resource-intensive admissions, anxiety, trauma/stress-related disorders, and heart failure.
Physicist Jun Ye proposes building a highly stable laser inside permanently shadowed lunar craters, leveraging their extremely low vibrations and temperature to achieve unparalleled precision. This could form the backbone of a lunar time scale, GPS-like navigation, and space-based optical atomic clocks.
Researchers developed a new tool to track ancient climate from wetland sediments, revealing turbulent environmental past in the Mediterranean. People adapted creatively, developing new technologies and strategies, such as floodwater farming and herd animal management.
A new study presents dual immunization against respiratory syncytial virus (RSV) using RSVpreF and nirsevimab, showing reduced hospitalizations among infants in France. The study found that this combined approach demonstrates potential for enhanced RSV prevention and protection
Researchers studied how hibernation affects the visual brain of squirrels, finding that certain neurons undergo quick structural changes during deep sleep and arousal stages. These changes reverse within hours after waking and have no lasting effects on neuron structure six months after hibernation.
High-altitude exposure disrupts the gut ecosystem, leading to dysbiosis, impaired barrier function, and increased intestinal permeability. The gut microbiome influences host energy metabolism, immune responses, and acclimatization capacity, and alterations are linked to diseases such as metabolic disorders and colorectal cancer.
Stefan Isaac will investigate mitochondrial DNA packaging and gene expression using novel sequencing-based assays. He aims to understand the fundamental mechanisms of mitochondrial energy production and how cells regulate this process.
A long-term study of patients treated with flow diversion devices (FDDs) for intracranial aneurysms revealed excellent safety profiles, with no significant differences in outcomes between various FDD platforms. The study found that multiple FDDs were associated with a higher risk of insufficient closure and delayed complications.
A new study shows that an AI-powered CPR coaching agent can significantly improve survival rates by providing more accurate and comprehensive instructions. ChatCPR scored 100% on guideline-based CPR checklists and outperformed human dispatchers in guiding bystander resuscitation, with a 36-point gap in advanced steps.
A study found that school anthems referencing local mountains, such as Mt. Takao, correlate with the use of nearby green spaces for educational activities. This suggests a potential link between symbolic cultural representations and concrete actions in nature-related education.
Researchers discovered that stem cells can mature into potent antimicrobial cells when infected with bacteria, sacrificing their own lifespan to prevent prolonged infection and promote tissue repair. This newfound mechanism may hold potential for understanding inflammatory diseases like Crohn's disease.
A Rutgers-led study offers a hopeful twist on the classic game theory problem, suggesting that cooperation can emerge naturally without special rules or genetic ties. By keeping track of opponents, individuals can react in the same way, leading to cooperation's emergence as an emergent property.
The study demonstrates a rational precursor design principle for heavy-pnictogen-based III–V nanocrystals, enabling safer and more scalable semiconductor quantum dot synthesis. Metal-amide species play a central role in controlling the reduction of heavy-pnictogen precursors.
A new report by Frontier Economics reveals that EMBL-EBI's open data resources support growing numbers of scientists and innovators worldwide, driving £11.8 billion in annual productivity gains. The report highlights the critical role of these resources in enabling breakthroughs across science, medicine, and biotechnology.
Tomas Grejtak has been selected for the Early Career Award from the Society of Tribologists and Lubrication Engineers (STLE) for his research on wear, friction, and material deformation. The award recognizes his contributions to advancing the field of tribology and improving machine efficiency.
A study published in PNAS found that faster decision-making in complex strategic situations leads to better outcomes. Researchers analyzed professional chess games, correlating speed with quality and suggesting intuition plays a key role in human decision-making.
Researchers found that personalized, engagement-based ranking algorithms lead to polarized and less accurate beliefs, while bridging-based and intelligence-based ranking algorithms promote consensus and accuracy. Alternative algorithms could help social media platforms support more positive values.
Researchers at Northwestern University and NIH emphasize the need to define plagiarism in AI-assisted research writing, as intellectual theft can occur without proper credit. The commentary recommends revising definitions of research misconduct to include GenAI tool misuse, promoting more responsible use.
After Dobbs v Jackson, US abortion management shifted towards expectant approaches in ban states, with persistent reliance on suboptimal misoprostol-only regimens. State-level abortion bans were associated with a decrease in management options for individuals with spontaneous abortion in ban states.
New research from North Carolina State University predicts data center power demand will increase by up to 57% by 2030, leading to higher electricity costs and CO2 emissions. The study finds that regional price increases will vary depending on where new data centers are built.
Researchers discovered that disrupted PTH1R signaling drives abnormal cementum growth and tooth-bone fusion in adult mice, leading to severe dental complications. The study identified the loss of PTH1R signaling as a critical molecular safeguard against excessive cementum formation.
In this study, researchers investigate the photocurrent response of a bilayer atomically thin antiferromagnet, discovering a finite current generated by illumination even without applied voltage. The direction of the photocurrent reverses between two antiferromagnetic states, directly reflecting the material's magnetic configuration.
Scientists at Kaunas University of Technology discovered that low-frequency ultrasound can dissociate erythrocyte aggregates into single cells, decreasing blood viscosity. This effect may improve oxygen exchange and support treatment of cardiovascular diseases, Alzheimer's disease, and diabetes.
Scientists have identified novel peptides in carpenter ant venom that contribute to the ants' hygiene and provide an external immune defense against pathogens. The findings, published in Science Advances, offer new avenues for medical drug discovery and understanding of insect community health.
A new study by University of Nottingham researchers explores the impact of positive emotions on climate creativity and behavior. The study found that inspiring hope can lead to increased levels of creative problem-solving around sustainability and climate change.
TEGNet accelerates optimization in thermoelectric generator design by predicting performance with high accuracy and speed. The AI model enables designers to freely combine independent models for various materials, enabling complex structure exploration and high conversion efficiencies.
A systematic review by 16 leading researchers at Rutgers University and other institutions highlights recurring problems in studies of infection-associated chronic illnesses, including the failure to prove participants have the relevant pathogen. The authors propose a framework for rigorous study design to confirm diagnoses, choose com...
A new study reveals how ancient galactic collisions can destroy stellar discs, affecting star formation and galaxy structure. Simulations show that rotating discs often formed earlier than thought but can be partially or completely destroyed by major mergers.
Researchers at TU Wien have shown that water molecules' structures impact charged particles in electrochemistry. The team found that ions with stronger effects on surrounding water create more order, leading to lower entropy and reduced attachment to surfaces.
Researchers at the University of Toronto and the University of Ottawa have discovered large volumes of natural hydrogen in the Canadian Shield, which could provide a domestic source of cost-effective energy. The study suggests that harnessing this resource could reduce greenhouse gas emissions and support local industry hubs.
Osaka Metropolitan University researchers developed a light-driven method to rapidly collect microscopic targets, outperforming traditional techniques. The technique concentrates bacteria between 1000-10,000 times faster than existing approaches, paving the way for early disease detection and analysis of nanoparticles.
A recent study reveals that nearly one in three adolescents with cannabis use disorder (CUD) experience treatment delays, highlighting the need for system-level improvements. Younger adolescents, males, White non-Hispanic youth, and those in residential rehabilitation and outpatient settings are particularly at risk.
Researchers at Brown University found that payments to Medicare Advantage brokers more than doubled between 2014 and 2022, rising from $3.9 billion to roughly $10 billion a year. The study also revealed that broker involvement is common and growing, with 70% of Medicare Advantage beneficiaries generating renewal commissions.
A new study presents tezepelumab as a safe and effective treatment for severe asthma in underrepresented populations. The therapy reduces exacerbations by 70% and improves lung function, quality of life scores, and asthma control. It is particularly effective in patients with Type 2 asthma and those with comorbid COPD.
A millennium-old dingo was deliberately buried by Barkindji ancestors with great care, suggesting an ongoing relationship between local people and dingoes. The discovery provides new insights into ancestral dingo burial practices extending beyond southeastern Australia.
A new study found that coastal farmlands in the Mid-Atlantic region are losing land at a rate nearly twice as fast as previously thought. Between 1984 and 2022, approximately 25,000 acres of farmland were lost to sea level rise despite preventative measures taken by local farmers.
A new study found that childhood maltreatment can increase the risk of intimate partner violence victimization in young adulthood. The researchers identified three main psychological characteristics: low subjective wellbeing, conduct problems, and aggression.
Researchers developed a microcomb-driven terahertz wireless communication system that surpasses conventional limits by achieving 112 Gbps data rates in the 560 GHz band. This breakthrough uses high-frequency stability and low phase noise of microcombs to generate a low-noise terahertz carrier.
Researchers developed transparent hybrid metal halide glass scintillators that overcome light scattering and monochromatic limitations in X-ray imaging. The materials achieved high spatial resolutions of 18.8 and 22.5 lp mm⁻¹, nearly twice those of previously reported crystalline composite counterparts.
The SO320/1 expedition aims to investigate the formation of the 1,000km-long Hess Rise plateau using various models and multiple research instruments. The team will test three scenarios for its formation and collect rock samples from the seafloor for further analysis.
Research suggests that switching to a nutritious diet can improve memory, but does not fully reverse cognitive deficits and impairment caused by high sugar intake. Diets high in added sugar show little evidence of recovery, highlighting the potential detrimental effects on brain health.
A new study introduces a physics-guided mixture density network that improves real-time hydrodynamic forecasting in canal systems. The model reduces mean absolute error and root mean square error by over 25%, offering a more reliable tool for managing large-scale water diversion infrastructure.
Researchers at Cold Spring Harbor Laboratory discovered how dehydration enables calcium to pass through the NMDAR channel, revealing key molecular mechanisms underlying learning and memory. This finding has implications for brain development and disease, including GRIN disorders that cause severe developmental disabilities.
A new study found a steady rise in children's mental health concerns during routine primary care visits, with anxiety-related visits increasing by 300% over 10 years. The study highlights the growing role of pediatric primary care in addressing mental health needs and calls for more training and resources to support this shift.