Researchers propose a unifying framework to rebuild brain–spinal communication in SCI patients, enabling closed-loop neurotechnology to support stable or adaptive function. The study introduces three technological routes to address communication loss, state mismatch, and learning failure.
Researchers developed a new class of stretchy bioelectronics that can stick to biological tissue and relieve hypertension while causing less damage to surrounding tissue. The CaroFlex device uses gentle electrical frequencies to modulate the baroreceptor reflex, providing effective treatment for drug-resistant hypertension.
A study published in Science Advances reveals that neuronal hyperactivity triggered by rogue antibodies is a key driver of the severe autoimmune brain disorder IgLON5 encephalitis. The research also highlights similarities between this condition and Alzheimer's disease, suggesting potential therapeutic targets.
Weight loss followed by weight regain, known as 'yo-yo dieting,' is not supported by strong scientific evidence. The authors found that benefits of losing weight outweigh the theoretical risks of weight cycling in most cases. Repeated attempts at weight loss can provide meaningful periods of improved metabolic health and quality of life.
Researchers at Penn have created quasiparticles that combine the speed of light with strong matter interactions, enabling signal switching needed in computation. This advancement could lead to faster, more energy-efficient photonic AI chips and pave the way for basic quantum computing capabilities.
A new study led by University of Maryland scientist Madeleine Youngs reveals that meltwater flowing off ice shelves changes the ocean's circulation patterns, driving even faster melting. This self-reinforcing chain reaction contributes as much to rising sea levels as direct atmospheric warming.
A new review article synthesizes research on the mental and psychological health impacts of greenspace on advantaged and disadvantaged children. Nearly 60% of studies found that people living with disadvantage benefitted more from natural environments, with reduced anxiety, behavioral difficulties, and improved cognitive functioning.
Climate-driven instability is transforming dengue transmission in Vietnam, requiring a new approach to surveillance and early warning systems. Researchers propose a hybrid system incorporating climatic thresholds, probabilistic modeling, and One Health practices to proactively reduce outbreak scale.
Climate change is reshaping the infectious disease landscape, leading to new diseases emerging and old ones reappearing. The report identifies priority research areas to strengthen infectious disease attribution science and build resilient public health response systems.
Researchers at FSU have discovered a way to forecast winter weather patterns up to six months in advance by analyzing the stratospheric polar vortex. This new approach uses climate patterns like El Niño-Southern Oscillation to predict the vortex's behavior, allowing for more accurate forecasts of extreme weather events.
Researchers tracked black sea bream using ultrasonic biotelemetry to observe their reproductive behavior during spawning seasons. Males made frequent upward and downward movements, while females remained near specific oyster rafts, suggesting different strategies for reproduction and energy conservation. This study provides new insight...
The City University of Hong Kong has developed a new generation of aqueous zinc-based batteries offering improved safety, higher power, lower cost and environmental sustainability. The breakthrough addresses large-scale energy storage challenges, providing ideal backup power for data centers.
Researchers establish a population-dynamics framework to quantify Boltzmann behavior, introducing a stability rule and splitting factor for energy-level selection. This enables predictive design of dual thermally coupled architectures and phosphor-based thermosensing patches with high sensitivity and resolution.
The University of Cologne's researchers will continue to work on innovative treatments for lymph node cancer and study plant responses to environmental changes. The Collaborative Research Centres have received a total of approximately €39 million in funding, highlighting the university's strength in collaborative research.
Four Okinawa startups - CancerFree Biotech, Perseptive, Strout Inc., and Tlaloc Blue - have graduated from the OIST Innovation Accelerator, demonstrating progress in healthcare, communication, aquaculture, and environmental technologies. The graduates plan to expand their businesses domestically and internationally, with support from f...
A study finds that a warming climate leads to more shallow tropical cyclones, which differ from deep cyclones in terms of hazard risks. Shallow cyclones can produce comparable extreme rainfall events as deep cyclones, highlighting the need for reassessment of future cyclone-related hydrological hazards.
A systematic review of global perspectives on AI in educational leadership reveals that AI can empower leaders in improving decision-making and administration efficiency but also poses technical, ethical, and socioeconomic implications. The study suggests a human-centered approach between AI and educational leaders, emphasizing the nee...
Research suggests that tumors with poor prognosis outcomes may be infected with bacteria, which can weaken treatment by altering local immunity and damaging tissue structure. The authors propose using familiar carrier-free antibiotic and chemotherapeutic drug combinations to restore treatment sensitivity in these tumors.
A new heat transport regime, known as hydro-thermoelastic transport, has been discovered in ultrathin semiconductors like molybdenum disulfide and molybdenum diselenide. This regime shows that thermal diffusion is highly impeded, leading to unexpected behavior such as phonon hydrodynamics.
A new reactor design efficiently converts carbon dioxide into methane using microbial electrosynthesis systems, achieving high energy efficiency and scalability. The system produces nearly two gallons of methane per liter of reactor volume per day, making it a potential pathway for converting CO2 into a storable fuel.
Researchers at Newcastle University have created an electrically conductive, water-based reversible adhesive that can join electronic components and allow for their reuse or recycling. This technology has the potential to address the massive problem of e-waste globally.
A recent cohort study found that COVID-19 vaccination is associated with a lower risk of SARS-CoV-2 transmission. The study suggests that vaccination may indirectly reduce overall exposure to the virus.
Researchers discover ultra-faint galaxy LAP1-B with record-breaking low oxygen abundance and elevated carbon-to-oxygen ratio, suggesting it is the 'ancestor' of fossil galaxies near our Milky Way. The team's findings provide a historic window into the earliest stages of galaxy assembly.
Additives in plastics represent a major understudied frontier in recycling science. Mainstream recycling technologies face distinct challenges with additives, including gradual accumulation of unwanted compounds and limited detection methods.
Scientists have developed a theoretical model showing that atomic clocks can observe the quantum superposition of time. The researchers used modern techniques to detect the signature of entanglement between the clock's motion and its internal energy, improving sensitivity by 100-1000 times.
A new coupled elastohydrodynamic–acoustic framework enables high-resolution ultrasonic measurement of dynamic film thickness in lubricated rolling bearing contacts. The method supports in-situ, noninvasive monitoring and improves accuracy by accounting for real contact geometry, elastic deformation, and cavitation effects.
This study developed a diagnostic strategy for hepatocellular carcinoma based on serum protein glycosylation signatures. Serum IgG was analyzed for differential N-glycosylation patterns to differentiate HCC from healthy controls and liver cirrhosis.
A Chinese endoscopy-screened cohort study found that genetic risk and lifestyle factors independently contribute to upper gastrointestinal cancer risk. Integrating genetic risk with lifestyle information may improve risk stratification and identify individuals most likely to benefit from screening and prevention.
A multi-omics and machine learning framework reveals plasma SBDS as a key protective factor and therapeutic target in PSC, advancing our understanding of the disease's mechanistic pathway.
A single dose of psilocybin provided rapid relief from depressive symptoms within a few days, with effects persisting for over three months. The treatment showed a significant advantage over SSRIs, with an average reduction of 9.7 points on the MADRS scale.
Children and adolescents in Gaza who suffered penetrating traumatic brain injury during armed conflict experienced substantial morbidity and mortality. Survivors often endured neurological impairments and long-term psychosocial challenges.
Scientists are calling for a fundamental rethink of climate and biodiversity models to address the scale and complexity of crises ahead. The current models focus on incremental change rather than transformative transformations needed for a safe and just future.
A single dose of psilocybin was associated with rapid antidepressant effects, persisting for more than 3 months. The study suggests that psilocybin may provide a rapid and relatively long-lasting antidepressant effect on major depressive disorder.
New review highlights emerging complexity of senescent cell populations playing both protective and harmful roles in aging. Precision geroprotection aims to selectively eliminate maladaptive senescent cells while preserving beneficial ones.
Researchers at UTMB have identified the ATR enzyme's role in preventing chromosome breaks during DNA copying. Without ATR, replication machinery falls apart, leading to increased chromosome breaks and potential risks for healthy tissue.
Researchers have created drink recipes that combine essential nutrients, including omega-3 fatty acids, to support astronauts' health during longer space missions. The customizable beverages offer mix-and-match flavors and sweetness levels, providing a potential solution for filling nutrient gaps in astronauts' diets.
IEC-HS is a rare but potentially fatal complication of CAR-T therapy, characterized by sustained inflammatory response and distinct biochemical differences from CRS. Targeted therapies, such as interleukin-1 blockade, are gaining attention for its management.
A team of researchers proposes a deep learning architecture called CCDNN to learn correlated representations for multi-source data fusion. The method demonstrates promising performance, surpassing existing methods in reconstruction tasks and achieving better results in industrial fault diagnosis and remaining useful life cases.
A new framework, 'gentle power,' introduces a collaborative approach to conservation that combines trust, shared expertise, and ecological outcomes. This approach has been successful in Tokyo's Zushi-Onoji satoyama landscape, supporting biodiversity while maintaining water cycles and agricultural productivity.
A study published in Chinese Neurosurgical Journal shows that heat-based therapy, such as RF-TC, alters brain network connectivity in patients with medically refractory epilepsy. This may help predict treatment response and guide personalized interventions.
Hanyang University researchers found that a coating thickness of 2.5 nanometers is necessary to prevent harmful side reactions in sulfide-based all-solid-state batteries. The study showed improved electrochemical performance and cycle life with this minimum effective coating thickness.
Researchers identify RAGE receptor as key driver of age-related increase in breast cancer metastasis. Analyzing mouse models and human data, they found that aged mice develop more lung metastases than younger mice, despite similar primary tumor growth.
The study reveals climate change is a growing social crisis, disrupting connections and community belonging, with impacts felt through heatwaves, air pollution, and economic strain. Vulnerable populations, such as those on low incomes or living with disability, are disproportionately affected by climate-related isolation.
A breakthrough in CRISPR technology uses DNA to guide enzymes, overcoming the limitations of RNA-based systems. This new approach enables precise control over disease-causing signals, reducing unintended effects and costs, while opening doors to new treatment options.
A new study finds that coal pollution reduces global solar electricity output by 5.8%, equivalent to 111 TWh of lost energy, with aerosol-related losses reaching 74.0 TWh annually. This constraint on the clean energy transition underscores the need for pollution control measures to maximize renewable energy output.
A new study by Colorado State University reveals that Latin America and southern Europe favor 'mutualism' while the US and Canada prioritize 'domination'. This divergence in views is linked to European colonization centuries ago. The research emphasizes the importance of considering cultural differences in wildlife management policies.
A study published in Insect Systematics and Diversity documented over 100 species of Platydracus beetles, with more than half being new discoveries. The findings highlight the vast gaps in known biodiversity, even among well-studied groups like rove beetles.
Multi-year La Niña events are becoming more common due to two distinct pathways that can lead to long-lasting cooling in the Pacific Ocean. The study found that a pattern of anomalous sea surface temperatures south of the equator, known as the South Pacific Meridional Mode (SPMM), can sustain La Niña by slowing its natural decay.
Scientists at Tampere University created a 3D printed ceramic implant material that closely mimics real human bone. The findings advance personalized bone regeneration and may lead to more effective treatments for bone defects.
A recent study published in Journal of Functional Foods found that paraprobiotics derived from Enterococcus faecalis FK-23 can protect against sperm toxicity caused by bisphenol A (BPA) exposure. The researchers observed improved sperm motility and reduced oxidative stress markers when rats received FK-23 despite BPA exposure.
Researchers are developing brain-inspired hardware that integrates memory and computation, enabling robots to process information in parallel with minimal energy use. The new systems mimic the event-driven processing of the human brain, allowing robots to achieve perception, decision-making, and action with human-like efficiency.
Mr. Takenobu Nakagawa receives prestigious MEXT Minister’s Award for excellence in research support, recognizing his work on histological specimen preparation and standardization of immunohistochemistry protocols. The award highlights the vital role of technical specialists in driving innovation through specialized expertise.
Antimicrobial peptides influence amyloid fibrillization through three mechanisms: structural compatibility, directional seeding asymmetry, and surface-mediated catalysis. This review proposes a bidirectional pathogen-amyloid feedback loop, linking infection and neurodegeneration.
Researchers developed a new method called sm-PORE-cupine to study individual RNA molecules and reveal how their structures influence gene regulation. The technology provides deeper insight into how RNA structure affects cellular function and could help identify new therapeutic targets for diseases such as viral infections.
A research team led by POSTECH developed an AI framework that can predict and account for microscopic defects in metal 3D printing, improving the reliability of metal components. The framework achieves a Mean Absolute Error (MAE) of just 9.51 MPa, outperforming conventional approaches.
Researchers developed a novel smart hydrogel framework that can store multiple pages of information, revealed under different environmental conditions. The technology uses light-induced crosslinking and anti-opal structural colors to create a highly secure and aesthetically striking platform for information encryption.
The study revealed that sodium binding and electron transfer drive a precise dual trigger, pumping sodium ions across the cell membrane. This understanding provides a powerful new framework for designing targeted antibacterial drugs.
Researchers found AI agents tend to prioritize completing tasks over evaluating their safety and context, leading to 80% of undesirable actions and 41% of damage. The study identifies recurring failure patterns, including execution-first bias and request-primacy.
A new study published in Neurology suggests that maintaining good overall brain health can help reduce the impact of Alzheimer's-related changes on cognitive function. The research found a link between higher socioeconomic status and reduced cognitive vulnerability, highlighting the importance of promoting healthy lifestyles.
Researchers discovered that sea squirts package adhesive materials into nanocondensates, which deliver them to the destination and unpack for use. This mechanism is distinct from mussels' adhesion strategy, providing clues for developing bio-adhesives to assist in seaweed cultivation.