A recent study found that antibiotic-resistant bacteria are present in the gut microbiomes of American black bears in eastern North Carolina. The researchers also discovered that these pathogens can be dispersed through bear feces, making the bears a potential indicator species for environmental changes.
New research from Trinity College Dublin found playing an instrument, taking a foreign trip, and socializing boost cognition in midlife. Lifestyle interventions can strengthen cognitive reserve decades before disease onset.
Researchers found that crabs' iconic sideways walk originated from a single, forward-walking ancestor around 200 million years ago. This rare innovation likely contributed to the ecological success of true crabs by making their escape direction unpredictable.
A new multicenter study finds that reoperative surgical mitral valve replacement demonstrates significant long-term survival benefits over transcatheter mitral valve-in-valve procedures in patients with failing bioprosthetic valves. At five years, rSMVR patients had lower mortality and more favorable valve performance.
A study by Geisel School of Medicine researchers identifies specific macrophage populations that help coordinate anti-tumor immunity, while others support tumor growth. By selectively targeting these immune programs, cancer treatments may be improved without eliminating entire immune cell populations.
A study on Spanish transhumance identifies three distinct types of systems, aligned with agroecological principles, offering insights into sustainable livestock farming. The findings highlight the need for greater political support and a regulatory framework to protect this ancient practice.
Measles outbreaks are accelerating globally, with declining vaccination rates and gaps in routine immunization coverage contributing to the resurgence. The disease can cause serious complications, including pneumonia, encephalitis, and death, particularly in young children and immunocompromised individuals.
Researchers found that brains consider grammatical constituents when anticipating next words, unlike AI systems which rely on predictive context. The study used magnetoencephalography and behavioral tasks to measure brain activity and word prediction accuracy.
The ORNL team is developing AI-enabled pixel detectors that can process massive data streams directly at the source. Spiking neural networks will be used to identify patterns and extract valuable signatures from particle interactions in real time.
SGLT2 inhibitors reduce proximal tubular sodium reabsorption by suppressing NHE3 via the SGLT2-MAP17-NHE3 microdomain. This effect is context-dependent, with distal compensation (NCC upregulation) possible. Clinical evidence shows reduced ascites, fewer paracenteses, and improved natriuresis.
Researchers discovered a biomarker that can predict disease progression and mortality in patients with severe heart failure. Mid-regional pro-adrenomedullin (MR-proADM) levels are associated with greater disease severity, mortality, and heart failure events.
The Kura-Araxes culture's multi-ingredient cuisine highlighted the central role of dairy products, fruit, and grape-based beverages. The discovery sheds new light on the daily life and culinary traditions of these communities, suggesting a low level of social stratification.
Researchers have discovered a new species of basal medusozoan, Paleocanna tentaculum, in fossil specimens found in Saint-Joachim, Quebec. The ancient creature, closely related to modern jellyfish, is a rare find due to the limited preservation of soft-bodied organisms.
The study sequenced and decoded the complete genetic information of rose plants, producing the first rose pangenome. This reveals a complex evolutionary history shaped by gene transfer and environmental adaptations.
A team of scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) has made a significant breakthrough in treating deadly non-tuberculous mycobacteria (NTM) infections. They have developed new compounds, including rifamycin candidates, which show promise in treating M. abscessus and other rapidly growing NTMs.
Researchers at Umeå University have identified NUP98 and NUP153 as key host factors in orthoflavivirus infection, which replicates in the cytosol of human cells. The proteins play a crucial role in viral replication and protein production, and their interaction with viral RNA regulates structural and non-structural protein ratios.
Binghamton University's new initiative aims to advance artificial intelligence for the public good by educating students on foundational AI principles, workforce applications, and ethical considerations. The three-year, $900,000 program includes a free online microcredential and student research opportunities.
The study found that women's cardiovascular disease is biologically different from men's, with greater sensitivity to cumulative risk exposure and more severe downstream consequences. Researchers emphasize the need for continued investment in CVD research to address sex-specific disease mechanisms and life-course risk accumulation.
The Individual Brain Charting project has released its fifth update with a new set of cognitive tasks, expanding the dataset to 40 hours of scanned data per participant. This provides an exceptionally rich resource for studying individual variability in brain organisation and understanding brain function.
A new international survey reveals that adults with hypophosphataemic osteomalacia face a substantial disease burden, often under-recognised. The study calls for improved awareness, education, and coordinated care to ensure timely diagnosis and optimal treatment.
A study by the University of Kansas found that high school journalists learn business skills through practice and experiential learning, even if business concepts are not directly addressed. Student media advisers reported financial pressures and stressed the need for improved financial literacy education.
The study uses CRISPR/Cas9 to modify the transcriptional repressor SlMYB32, leading to increased flavonol and flavanone production in tomatoes. Key genes associated with these compounds are up-regulated in SlMYB32 mutants.
Terrence Sejnowski receives Scientific Breakthrough Award for his foundational development of Boltzmann machines, providing the architectural bedrock for deep learning and generative AI. His work has had a profound impact on modern artificial intelligence and tools like ChatGPT.
Researchers developed a new scale to measure the use of evidence in decision making, capturing four sources of evidence. The Evidence-Based Management Source Utilization Scale (EBM-SUS) shows promise for increasing transparency, accountability, and effectiveness in organizational management.
Researchers at Saarland University are developing smart implants that can continuously monitor and visualize the healing process of fractures. These customized implants can dynamically adapt to the healing process by becoming stiffer or more compliant as required, promoting bone regeneration through micromechanical stimulation.
A VHIO-led study identifies epigenetic changes caused by diet, tobacco, and pesticide exposure as risk factors for early-onset colorectal cancer. The study, published in Nature Medicine, confirms the influence of lifestyle and environmental exposures on cancer development in younger patients.
A new cobalt-based dual-atom catalyst significantly enhances oxygen reduction reaction performance while avoiding precious metals. The catalyst achieves remarkable catalytic activity and retains durability, enabling outstanding energy performance in zinc-air batteries.
Researchers develop a nature-inspired hybrid material that produces high-quality therapeutic proteins with nearly tenfold higher efficiency than traditional methods. The material's unique design enables it to adapt to different environments, alleviating hypoxic stress and activating cellular functions.
A recent study found that children from rural China are more prone to emotional issues, while urban children show more behavioral problems. These findings highlight the need for targeted interventions and underscore the impact of environment on mental health outcomes.
Scientists have discovered a natural extract that enhances the effectiveness of traditional sunscreens, providing longer-lasting protection against UV radiation. The new generation of sunscreens also offers antioxidant benefits, reducing the risk of skin cancer and premature aging.
The Insilico Medicine Longevity Board aims to accelerate the development of therapeutics targeting the biological processes of aging. The board, led by Andrew Adams, will oversee AI-enabled aging research and drug discovery.
Researchers develop new concept to accurately model wind turbine loads, focusing on local gusts' impact on material fatigue. This enhances turbine design and efficiency by reducing uncertainties in load estimations.
Researchers at University of Galway discovered a new therapeutic approach to combat Alzheimer's disease. They found that stimulating the brain's efficiency and balance may help alleviate cognitive decline and memory impairment. By blocking the activity of GABA receptors, they can reverse Alzheimer-like effects and improve cognitive per...
Researchers are unlocking secrets of Mechanohealth, a new paradigm focusing on maintaining the body's natural mechanical balance to prevent and treat disease. Studies have shown that macrophage mechanics directly determine anti-tumor activity and fibrosis can be reversed by disrupting key mechanical feedback loops.
A new species of coelacanth has been identified from a 150-year-old fossil, bridging a 50-million-year gap in the evolutionary history of Latimeriidae. The discovery was made using modern imaging techniques and has provided crucial insights into the evolution of one of the world's most iconic fish lineages.
A new study introduces the eLTER Framework of Standard Observations, a structured system to support consistent long-term environmental observation across Europe. The framework strengthens collaboration and improves data interoperability for studying gradual environmental changes.
Researchers found that a deaf person's brain can reorganize sensory systems through selective deactivation, not just increased activation. The auditory cortex in deaf individuals responds to visual stimuli with organized deactivations, representing visual spatial features.
The EVApeCognition Dataset is the largest and most comprehensive collection of experimental studies of great apes' cognition and behavior available globally. Researchers compiled over 262 experimental datasets from 150 publications, enabling unprecedented examination of how great apes think, learn, and understand their environment.
Researchers found that listening to one-minute recordings of forest sounds made people feel better, reporting more positive emotions and less stress. Local temperate forests produced the strongest effects, with familiar sounds triggering stronger feelings of awe and calm.
The University of Manchester has been recognized for its significant contribution to computer science with the third IEEE Milestone Award, honoring the invention of Manchester Code in 1948-1949. The code's self-clocking design enables reliable transmission and remains a key feature in modern digital systems.
Researchers developed a Variational Level Set Autoencoder (VLSet-AE) to automate contour recognition in SEM cross-sections of DRIE structures. The model achieved high precision, recognizing critical structural features with low average prediction error of 3.65% and correlation coefficient of 0.998.
Researchers at the University of Manchester have found that terrestrial hot spring microbiomes can transform industrial CO2 waste into biomass and other valuable compounds. This discovery could enable the production of value-added products directly from CO2-rich waste streams, reducing emissions while generating economic value.
Researchers discover cancer-driving genes in microglia of Alzheimer's patients, suggesting a link between blood cancers and the neurodegenerative disease. The findings could lead to new diagnostic tools and therapeutic options for Alzheimer's.
A study published in Nature Communications reveals how immune cell networks contribute to liver damage and fibrosis. The research team identified a key interaction between dendritic cells and γδ T cells, triggering pro-inflammatory signals that amplify inflammation.
Lindsay Squeglia, Ph.D. of the Medical University of South Carolina received the 2026 ACTS Award for Supporting an Excellent Translational Science Workforce. She is a leading figure in substance use prevention and adolescent brain development research.
A recent study from the University of Eastern Finland found that people with Parkinson's disease are using psychotropics more frequently than controls, even before diagnosis. The use of psychotropic medications increases as the disease progresses, reflecting emerging non-motor symptoms and worsening disease progression.
Researchers at KAIST developed a new technology using spin waves to process signals, reducing heat generation and power consumption. This breakthrough enables instantaneous frequency switching and is expected to pave the way for smart devices with less heat and longer battery life.
Researchers found AI voice clones to be up to 20% more intelligible than humans in various testing scenarios, including noise, age, and accent. This breakthrough raises questions about the potential applications of voice cloning technology.
A study found that long-term exposure to wildfire smoke was significantly associated with an increased risk of developing lung, colorectal, breast, bladder, and blood cancer. The risk increased with every additional microgram per cubic meter of fine particulate matter in the air.
Twenty-three young investigators from 16 countries received the ESCEO-IOF Young Investigator Awards for their outstanding abstracts submitted to the WCO-IOF-ESCEO 2026 Congress. The awards aim to support and attract young researchers to the field of musculoskeletal research.
The International Osteoporosis Foundation has awarded Professor Roland Chapurlat the prestigious IOF Olof Johnell Science Award for his seminal contributions to understanding and managing osteoporosis, osteoarthritis, and skeletal rare bone diseases. He is recognized as one of the leading clinical academics in the field worldwide.
Researchers developed a new method to identify intricate RNA structures that are likely to have significant biological functions. The multi-site DMS-MaP approach allows for direct measurement of RNA folding in cells, revealing key 3D structures and protein binding sites.
A study found that early myocarditis onset after immune checkpoint inhibitor therapy significantly increases the risk of death from treatment-related causes. Patients who developed co-occurring myositis and myasthenia gravis were also at a higher risk, with some cases leading to fatal outcomes.
A recent review highlights how AI enables precision treatment, continuous monitoring and individualized prognostic modeling for heart failure patients. AI integrates large-scale structured electronic health records and multimodal imaging to characterize cardiac structure and function, enhancing diagnostic accuracy.
Researchers at Ben-Gurion University found that altering water source distribution in a desert ecosystem improved mating structure and increased genetic diversity in wild populations. By establishing more territories for reproducing males, changes in resource management boosted population's variance effective population size.
Research found that gender-diverse teens reported higher rates of psychological stress and psychotic-like experiences, which can lead to depression, anxiety, and other serious mental health disorders. Bullying and unsupportive legislation drove these findings.
Researchers found that Cathepsin K (CTSK) reduces liver fibrosis by blocking the TGF-β/Smad pathway, which activates hepatic stellate cells. CTSK also induces apoptosis in these cells, contributing to anti-fibrotic effects.
A recent study from the University of Tartu found that young children who spend more time on screens and less time talking with adults tend to have weaker language skills. In contrast, daily interaction – rather than screen limits alone – plays a key role in early language development.
Nine European high school students completed a six-day simulated Mars mission in Portugal, operating rovers and conducting scientific experiments. The EXPLORE-2 mission aimed to develop young Europeans' STEM skills and team management capabilities, with participants designing their own mission plans and making operational decisions.
Researchers found that intralesional nivolumab reduced lesion size by an average of 60% and achieved complete pathologic response in 6 patients. The treatment also showed promise in treating high-grade and low-grade dysplasia, with 82.13% of treated lesions remaining cancer-free after 12 months.