A peanut mutant's embryo development failure is linked to AhZAR1, a receptor-like kinase essential for early embryogenesis. The AhZAR1 protein interacts with key signaling pathways, including auxin and brassinosteroid pathways.
A study of 1,200 musicians in five countries reveals the 'streaming paradox': while artists are more visible than ever, meaningful income remains elusive. Musicians face growing pressure to create engaging content and manage their online presence.
A recent UNH study reveals that New Hampshire ski industry professionals are increasingly concerned about climate change, with 85% expressing alarm or concern. The industry generates $278.8 million annually and supports over 10,000 jobs, highlighting the need for sustainable practices and advocacy.
Research published in Ethnicity & Disease found that self-employed Hispanic women report less high blood pressure, obesity, and poor health compared to their salaried counterparts. They were also more likely to exercise, with a nearly 11% higher rate of physical activity.
Researchers at ExCELLS/NIPS successfully determined the capsid structure of Melbournevirus at 4.4 Å resolution using cryo-EM. The study's 'block-based reconstruction method' improved resolution, revealing detailed arrangement of proteins constituting the massive capsid.
The Salk Institute will lead an ARPA-H-funded project to develop ultrasound-sensitive protein tools, wearable ultrasound delivery technology, and a translational path to the clinic for major unmet medical needs. The team aims to create a noninvasive therapy for conditions such as peripheral neuropathy.
Astronomers have identified a metal-poor star in the Large Magellanic Cloud, which is almost entirely hydrogen and helium with trace amounts of carbon and iron. Studying this low-mass star can help clarify our understanding of the first generation of stars, called Population III stars.
A new framework for brain-computer interfaces is proposed using single-neuron recordings, integrating clinical advances with existing technologies. The framework enables two closed-loop strategies: adaptive neural feedback systems and adaptive neuromodulation systems, facilitating the study of memory processing and concept cells.
Researchers have identified GSK3α as a common checkpoint controlling stem cell differentiation, maintaining self-renewal and preserving identities in various stem cell types. Inhibiting GSK3α demonstrates its fundamental role in regulating stem cell biology across developmental stages and species.
A new Northwestern University study confirms that US drug overdose deaths have continued to decline following a peak in August 2023, contrary to speculation of manipulated CDC data. The study highlights the importance of accurate data for public health response and calls for greater transparency in federal data systems.
Matei Zaharia's work on open-source systems like Apache Spark, Delta Lake, and MLflow has enabled large-scale machine learning, analytics, and AI at global scale. His innovations have made scalable computing accessible to researchers, nonprofits, and enterprises across every industry.
A recent study reveals that linker histone H1 binds to nucleosomes and creates a dynamic, flexible network that condenses chromatin. This new understanding suggests that chromatin behaves like a liquid-like 'glue' rather than a rigid structure.
A study published by the American Academy of Neurology found that a higher quality plant-based diet is associated with a lower risk of Alzheimer's disease and other dementias. Researchers compared participants based on their diet scores, finding that those who followed healthier plant-based diets had a lower risk of dementia.
The Department of Energy's Oak Ridge National Laboratory was recently awarded six Federal Lab Consortium awards for Technology Transfer Excellence. The awards recognize the successful transfer of technology from laboratory to industry, including a breakthrough suite of lithium extraction technologies that enable secure domestic supply.
A study of nearly 200,000 Amazon reviews reveals that the structure of online product reviews plays a crucial role in their helpfulness. The researchers identified nine possible structures of online reviews and found that different review structures are more or less helpful depending on how highly the reviewer has rated the product.
A new study from the University of Chicago suggests that smoking may be linked to dementia through a previously unmapped route between the lungs and brain, involving pulmonary neuroendocrine cells and exosomes that disrupt iron balance in neurons.
Researchers developed a nanophotonic platform to generate quantum optical Stokes skyrmion states with controlled topological invariant, eliminating the need for post-selection. This enables robust morphing of quantum information into free-space.
Scientists at NTU Singapore found that glycerol-3-phosphate acyltransferase (GPAT) amplifies α-synuclein toxicity by altering fat metabolism in brain cells. Targeting GPAT activity may offer a new strategy for treating Parkinson's disease.
Researchers are evaluating the state's domestic violence resources to better support survivors and prevent further abuse. Through a $257,384 grant, UCF faculty are analyzing data from various sources and surveying organizations that provide domestic violence services.
The Global Flourishing Study dataset, spanning two waves and 200,000 participants across 22 countries, is now publicly available. Researchers can access the data without pre-registration, expanding the study's impact on understanding human flourishing.
Researchers found that auxin's partner proteins serve as internal plant 'thermostats' that directly sense temperature and change genetic programs to direct root growth accordingly. This discovery could lead to engineering plants that withstand extreme temperatures, protecting crop productivity under challenging conditions.
A comprehensive review of artificial intelligence in steel modular structures' generative design reveals a shift from rule-based automation to integrated, data-driven solutions. The study proposes future directions for hybrid knowledge-data integration models and practical engineering deployment.
A study published in Cell Reports reveals a two-phase model explaining the origin of childhood B-ALL, involving hyperdiploidy and subsequent malignant transformation. Hyperdiploidy causes chromosomal instability, delaying cell differentiation and allowing rare clones to persist without triggering leukaemia.
Using new genetic markers, fruit breeders can predict flower sex type and seedlessness in muscadines and other grapes with high accuracy. The approach will save time and resources in developing new grape varieties, including the major challenge of creating flavorful seedless muscadines on self-pollinating vines.
Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer. The method allows for the measurement of three key features from the same sample: DNA duplication, genomic alterations, and gene activ...
Researchers developed a halide-perovskite metasurface strategy using dual quasi-bound states in the continuum (q-BICs) to overcome pump absorption and radiative efficiency limitations. The system achieved an external quantum efficiency of up to 98.8% and cooled materials from room temperature to -201 °C.
A recent genetic study analyzing DNA from 2 million people found that similar chunks of DNA are associated with both psychiatric disorders like depression and PTSD, as well as various physical ailments. This discovery could lead to more effective treatments that address both mental and physical health.
Researchers developed a flexible optical fiber that can be steered into the larynx to destroy hard-to-reach tumors, expanding outpatient laser treatment options. The device successfully reached 81% of targets in tests with a 3D-printed replica of a human larynx.
The Chancellor’s Innovation Fund Awards support cutting-edge research and development projects across various fields. Faculty recipients will use the funding to refine their technologies, build prototypes, and assess market opportunities. The awards aim to bridge publicly funded academic research with private financing, fostering entre...
A new enzyme from a fungus cultivated in sugarcane bagasse or wheat bran can promote cellulose pulp bleaching. The xylanase facilitates the removal of xylan fractions associated with residual lignin, increasing brightness and efficiency in subsequent stages of pulp processing. This non-toxic alternative reduces chemical load and has gr...
A 289-million-year-old mummified reptile has provided scientists with a unique window into the evolution of breathing and movement in ancient reptiles. The study found that the reptile's respiratory system is similar to that of modern reptiles, birds, and mammals, suggesting an efficient mechanism for respiration.
A new study found that targeted, case-based learning improved provider confidence and identified critical unmet educational needs in menopause care. Clinicians reported high satisfaction with the program and noted anticipated changes in clinical practice, such as increased comfort initiating treatment.
Researchers found that blocking clusterin, a molecule linked to stress and tumor growth, slows tumor growth signals and makes the cancer more responsive to cisplatin. The study's findings offer a possible strategy for treating cervical gastric-type adenocarcinoma, one of the most aggressive non-HPV associated cervical adenocarcinomas.
A national Canadian study found that older adults who are socially connected, physically healthy, and spiritually engaged are significantly more likely to experience complete mental health. Social support emerged as one of the strongest predictors, doubling the odds of achieving complete mental health.
Researchers are diversifying CAR therapy to overcome limitations, exploring engineered cell platforms like NK cells, γδ T cells, and macrophages. This expansion could treat a broader range of diseases, including lupus, infection, cardiac fibrosis, and senescence-related disorders.
A study reveals improved quality of mammal species descriptions from temperate regions, with authors from wealthy countries using more advanced techniques. The study, supported by FAPESP, analyzed 1,116 new species descriptions between 1990 and 2025.
A new study from University of Florida finds that employee perfectionism impact depends on alignment with supervisor's expectations and clarity in understanding. When employees' standards match supervisors', they experience less uncertainty, better performance, and higher job satisfaction.
Researchers have discovered a new species of glassfrog in Ecuador named after Neisi Dajomes, the first Ecuadorian woman to win an Olympic gold medal. The Dajomes glassfrog has uniformly green skin with a pebbly texture and a white membrane covered in light-reflecting cells on its underside.
Scripps Research scientists develop a new approach to building branched molecular structures, overcoming a technical obstacle that limited chemists' ability to assemble complex molecules. The method, using metal hydride selection, produces more than 50 new branched compounds with an unusually high degree of control.
A new study found that exposure to PFAS may weaken the immune system in adults, raising concerns about long-term health effects of these widely used chemicals. The research highlights the importance of reducing PFAS levels in drinking water to protect public health.
A small Dutch survey found that more than half of veterinarians believe they will see cases of animal abuse by falsification, akin to Munchausen syndrome by proxy. This recognition is alarming and warrants further investigation into animal welfare practices among veterinary professionals.
A new study by Mass General Brigham reveals that long-term exposure to excess weight is a stronger predictor of cardiovascular disease risk than BMI at a single point in time. Younger individuals with high cumulative exposure to excess weight are particularly at increased risk.
Research reveals strong global link between ancient subduction zones and formation of rare earth element deposits and carbonatites. Ancient tectonic processes are critical to locating economically viable rare mineral deposits.
Researchers have successfully initialized and detected nuclear spin states in a europium-based molecular crystal using laser light, achieving nuclear spin quantum coherence with a lifetime of up to two milliseconds. This breakthrough paves the way for scalable quantum computers and atomically precise qubit registers.
Researchers at Binghamton University have created a talking robot guide dog system that determines ideal routes and guides visually impaired users safely to their destinations. The system offers real-time verbal feedback and provides situational awareness, significantly enhancing the user experience.
A new study reveals that subsidence is a major driver of coastal flooding along Java Island, with rates of up to 15 centimeters per year. Groundwater withdrawal and agricultural water use are identified as key culprits, highlighting the need for active monitoring and mitigation.
Anglerfish species use lures for both attracting prey and signaling potential mates, with bioluminescent lures appearing around 34-23 million years ago. Researchers analyzed over 100 species to study the evolutionary history of lures, tracing changes from motion-based to glowing lures.
Researchers have developed light-driven nanorobots that can track down and collect bacteria, perform rapid 90° turns and selectively capture bacteria. The nanorobots enable controlled interaction with the microscopic world, opening possibilities for microbiology, biomedical research and targeted manipulation at the microscale.
The S2419 BioFront study aims to enroll over 700 patients with advanced renal cell carcinoma and test the safety and efficacy of a CBM588 capsule as part of an immunotherapy-based treatment. The trial seeks to improve outcomes for patients by leveraging the gut microbiome.
A new study reveals that human transformations in land cover have a substantially greater influence on landslide fatalities than physical factors, particularly in low- and lower-middle-income nations. This research highlights how increasing human pressure on nature worsens the vulnerability of socioeconomically disadvantaged people.
A new study found that breastfeeding practices vary significantly between urban slum and non-slum areas in India. Urban slum mothers tend to start breastfeeding earlier, while non-slum mothers are more likely to breastfeed only breastmilk for the first five months.
A Phase I clinical trial of a human monoclonal antibody for Lyme disease demonstrates its safety, tolerability, and pharmacokinetics. The treatment, TNX-4800, provides lasting serum concentrations and has the potential to offer passive immunity against the disease.
The European Association of Nuclear Medicine (EANM) has joined the EMUC26 congress to promote nuclear medicine expertise in urological cancers. The event will bring together healthcare professionals from various disciplines to discuss current practices and emerging innovations.
Research reveals inflammation in the GI tract changes how nerves are arranged, affecting intestinal muscle contractions. A protective stress response pathway helps neurons survive, preserving their structure and potentially offering a way to curtail persistent symptoms associated with IBD.
A Northwestern University study found that apolipoprotein B (apoB) testing is more effective and cost-efficient than standard cholesterol tests in guiding treatment and preventing heart attacks and strokes. The study suggests that apoB-guided care can improve population health and save lives at a lower cost.
A new study by the University of Ottawa found that emojis can negatively affect perceptions of competence and appropriateness in professional settings. The researchers discovered that using positive emojis with negative messages can create a sense of dishonesty, while negative emojis can lower overall competence perception.
Researchers at the University of Texas M.D. Anderson Cancer Center have identified a way lung cancer cells evade radiation therapy and developed a strategy to overcome this challenge using a DHODH inhibitor. The study found that inhibiting DHODH with leflunomide can help overcome radiation resistance by promoting ferroptosis, allowing ...
A recent study published in the Journal of Nutrition Education and Behavior found that a Food is Medicine and food literacy education program improved food-related knowledge and practical skills among rural, uninsured adults with type 2 diabetes. The Fresh Start FIM + Food Literacy intervention showed significant overall improvements i...
A recent study found a decline in long-term opioid prescribing in the US between 2015 and 2023, with a 24.3% decrease in patients receiving extended therapy. However, approximately 4.2 million US patients still received opioids for 90 days or longer in 2023, indicating the need for improved treatment models for chronic pain management.
The VCU Massey Comprehensive Cancer Center has completed the inaugural funding cycle of its collaborative drug discovery program with the Sanford Burnham Prebys Medical Discovery Institute. Two projects have received $50,000 each to advance innovative cancer drug discovery efforts.