Research reveals ATRX mutations cause DNA damage leading to premature aging symptoms such as shortened lifespan, cataracts and low bone density. The study found mice without the ATRX gene displayed problems in learning and memory, body growth and metabolism.
Researchers from NYU College of Dentistry and School of Medicine will explore the role of intestinal microbiota in promoting pancreatic carcinogenesis. The study aims to determine whether endogenous gut bacteria can affect pancreatic oncogenesis and identify potential targets for prevention and treatment.
A Canadian study found that more than half of lower-back MRIs ordered at two hospitals were either inappropriate or of questionable value for patients. Family doctors were more likely to order these tests compared to specialists, highlighting the need for better education on when to use MRI scans.
A new study in Canada has found that over 40% of healthy individuals are taking daily aspirin to prevent cardiovascular disease, despite recent literature suggesting its limited benefits. The study's authors hope to raise awareness among physicians and patients about the importance of discussing anti-platelet medication use.
A one-day training program designed by U of A medical researchers led to officers being more likely to recognize mental health issues during calls and less likely to use physical force. The training resulted in long-term behaviour change and saved the police force $80,000 due to increased efficiency.
Researchers at the University of Alberta have made a breakthrough in understanding how prion diseases spread between different types of animals. By studying the adaptation process, they aim to determine why certain strains can infect one type of animal but not another.
Researchers have discovered that gateways in the nucleus control chromosome structure and gene expression, impacting disease triggers.
A six-month study published in General Dentistry found that using a germ-killing mouthrinse twice daily significantly reduced plaque and gingivitis compared to brushing alone. The study involved 139 adults with mild to moderate plaque and gingivitis, showing a 26.3% reduction in plaque and a 20.4% reduction in gingivitis.
Research suggests that being overweight is a risk factor for gum disease, which can lead to chronic inflammation and other health issues. Daily brushing, flossing, and professional cleanings are essential for preventing gum disease and maintaining good oral health.
A UAlberta research team found that medications for Pulmonary Arterial Hypertension (PAH) could have adverse effects on the heart. ERAs decrease the strength of contraction in diseased right ventricles, which may be beneficial due to increased endothelin levels.
Researchers identified a genetic marker in over 300 women with breast cancer, finding that those with this marker were more likely to experience recurrence. This breakthrough could enable doctors to tailor treatment strategies for high-risk patients based on their unique genetic profiles.
Researchers have identified a new genetic mutation in the ARHGEF28 gene that is present in all cases of amyotrophic lateral sclerosis (ALS). The protein arising from this gene appears to play a critical role in the disease, and understanding its function could lead to targeted therapies.
A recent study published in Pediatrics found that 71% of pediatric patients attending specialty clinics in Edmonton used alternative medicine, while only 42% did so in Ottawa. The study highlights a need for better communication between doctors and parents about alternative medicine use, which can lead to potential drug interactions.
A research team at Plymouth University has identified a new group of growth factor receptors that signal to brain tumors, which are over-expressed and activated in certain tumors. The study shows that by interfering with the activation, tumor cells can be corrected, paving the way for non-surgical therapies.
NYU's Strauss is awarded NIH grant to develop a novel approach using oral blood to screen patients with periodontal disease for diabetes in general dental practices. The study aims to assess the accuracy, acceptability, and feasibility of this approach.
A research team led by Professor Zamaneh Kassiri has discovered that boosting TIMP3 levels can prevent the development of abdominal aneurysms. The study found that a protein called MMP2, despite being a contributor to heart and vascular disease, did not cause aneurysms when combined with TIMP3 deficiency.
Researchers at the University of Alberta have identified a rare type of cancer suppressor that can trigger cell death when targeted. By inactivating this gene, cancer cells are destroyed while healthy cells remain intact.
Researchers at the University of Alberta have discovered a potential treatment for Alzheimer's disease, finding that a diabetes drug can restore memory in brain cells. The team tested the drug on animal models with Alzheimer's and found significant improvements in memory function.
Researchers at OHSU School of Dentistry discovered a direct role of BDNF in regulating blood pressure, which may help prevent or treat high blood pressure. The study found that BDNF levels increase dramatically in nerve cells during hypertension.
A UAlberta researcher has developed 'homing beacon drugs' that selectively kill cancer cells while sparing healthy ones. These smart drugs use nano-technology to identify cancer cells based on a unique protein found only in them, allowing for targeted treatment and potential reduction in side effects.
A new study reveals that parents' dental fear can transmit to their children, with fathers acting as a major mediator in this process. The research analyzed 183 children and found that the father's emotional reactions significantly impact the child's perception of dentist anxiety.
Researchers found that children need at least seven minutes a day of intense physical activity to prevent weight gain and obesity. The study tracked over 600 kids aged 9-17 and showed that vigorous activity reduced the risk of unhealthy weight, while sedentary behavior was common.
A study by University of Alberta researchers found that providing educational information to physicians and patients improved osteoporosis treatment rates. The intervention led to a significant increase in follow-up testing and treatment, especially among men who are often overlooked as having the condition.
The NYU College of Dentistry and Graham Windham have partnered to provide regular dental care to over 650 children in foster care since 2011. This partnership has improved the children's oral health, while also providing a unique learning experience for dental students.
A global study has found that anaesthetic-related deaths have declined dramatically over the past five decades, with a 90% reduction in post-anaesthetic fatalities since before the 1970s. The study, published in The Lancet, also revealed an 88% decrease in mortality rates within 48 hours of surgery globally.
A 6,500-year-old human jaw bone with a tooth showing traces of beeswax filling has been discovered, offering evidence of ancient dentistry in Europe. The beeswax was likely applied to reduce pain and sensitivity from a vertical crack in the tooth.
Researchers at UofL School of Dentistry have discovered a way to prevent inflammation and bone loss surrounding teeth by blocking the natural signaling pathway of enzyme GSK3b. This finding has implications for preventing periodontal disease, a chronic inflammatory condition causing tooth loss.
University of Alberta medical scientists have made a groundbreaking discovery in understanding the structure of molybdenum, a critical metal in human health. The research reveals two forms of the molecule with distinct functions, providing new insights into diseases such as metabolic and respiratory disorders.
Researchers found that individuals with a history of kidney stones are more susceptible to developing serious kidney problems and kidney failure, particularly women under 50. The study's results highlight the importance of screening for risk factors in patients with a history of kidney stones.
A study published in PLoS ONE found a significant association between high levels of urinary BPA and severe coronary artery disease. The research team analyzed data from 591 patients and found that those with severe CAD had higher levels of urinary BPA, suggesting a potential link between the chemical and heart disease.
A USC study found that poor oral health is connected to lower academic performance and more absences from school for disadvantaged kids. Children with tooth pain were four times more likely to have a low GPA, and dental problems caused an average of 2.1 days of missed school per year.
Researchers have developed a new stem cell therapy that uses patient's own cells to regenerate craniofacial tissues, resulting in greater bone density and quicker bone repair. The treatment is best suited for large defects such as those resulting from trauma, diseases or birth defects.
Medical researchers at the University of Alberta found that parents prefer terms like 'large' or 'gaining too much weight' when discussing their child's weight, rather than the term 'obese'. This suggests that using more neutral and descriptive language can reduce stigma and improve the physician-patient relationship.
Researchers at the University of Alberta discovered a link between sodium and calcium regulation in the body. Excessive sodium intake can lead to calcium depletion, causing thin bones and osteoporosis, while high urine calcium levels increase the risk of kidney stones.
Researchers identified genetic markers influencing protein levels regulating oestrogen and testosterone in the bloodstream, near genes related to liver function and type 2 diabetes. These findings highlight an important connection between metabolic and reproductive systems in men and women.
A recent study by the Peninsula College of Medicine and Dentistry found that binge drinking in older adults is associated with an increased risk of cognitive decline. Participants who reported binge drinking at least once a month were 62% more likely to experience significant declines in cognitive function and memory.
Researchers at OHSU School of Dentistry discovered that TDP-43, linked to ALS and other neurodegenerative diseases, activates multiple molecular pathways when genetically manipulated. The study found that the loss of TDP-43 results in widespread gene activation and altered splicing, which can be reversed by restoring TDP-43 expression.
A new study found that people living near the coast tend to have better health than those living inland. The analysis showed that the link between living near the coast and good health was strongest in economically deprived communities.
West Nile virus infection causes breakdown of two vital proteins, claudin and JAM, leading to accelerated degradation of the blood-brain barrier. Researchers hope to design drugs that prevent brain infection by understanding this mechanism.
The UCLA School of Dentistry has received a $5 million NIH grant to create a comprehensive research training program for dentist-scientists and oral health researchers. The program aims to cultivate the next generation of leaders in science and research.
Researchers at the University of Alberta discovered a link between DHA intake and improved memory, with higher levels of DHA in the hippocampus leading to better cell communication. Supplementing with DHA may help prevent age-related declines in brain DHA levels.
Researchers will test the Incredible Years Teacher Classroom Management course on 80 primary school teachers in Devon, Plymouth, and Torbay. The study aims to improve pupil socio-emotional well-being, academic attainment, and teacher emotional well-being, with potential cost-savings for educational support and mental health services.
Researchers found that cancers with disorganized traffic systems result in lower survival rates and are more difficult to treat. A mathematical equation could help doctors determine the best course of treatment by identifying the complexity of each cancer type.
A natural compound found in fruits, nuts and red wine has shown improved physical performance and endurance in lab models. Researchers plan to test resveratrol on diabetics with heart failure to improve heart function and exercise capabilities.
A new model predicts the effectiveness of weight-loss groups based on their psychological meaningfulness to members. The study aims to generate a comprehensive understanding of group participation's impact on health and contribute to future development of weight-management programs.
A large non-commercial study found that cannabis' main active constituent, THC, does not slow the course of progressive multiple sclerosis. However, participants with lower disability levels showed some potential benefits from THC treatment.
Researchers at the Peninsula College of Medicine and Dentistry have identified a key player in the immune system that may protect against Alzheimer's changes. The CCR2 gene was found to be associated with memory in people, suggesting that strengthening this part of the immune system could slow the disease.
A new study has identified a genetic factor associated with lean type 2 diabetes patients, indicating that genetic predisposition may vary depending on body type. The 'Jack Spratt' gene is linked to an increased risk of the disease in lean individuals, contrasting with obese patients where other factors are more influential.
Researchers found that verbal and physical aggression between parents correlates with increased oral health problems in children. The team developed an intervention to help couples improve conflict resolution and parenting skills, aiming to reduce risk factors for poor oral health.
A new telehealth program by the University of Alberta helps rural COPD patients in northern Alberta communities. The program uses telehealth technology to conduct pulmonary rehab sessions and provide consultations with pulmonologists, resulting in improved quality of life and increased exercise tolerance after two months.
Researchers at the University of Alberta have discovered a genetic mutation that can predict heart failure in certain individuals. The team, led by Howard Young, will screen blood samples from 750 patients to identify mutations in phospholamban, a protein linked to heart disease.
Researchers at NYU College of Dentistry will screen subjects and collect biological samples to contribute to the overall project on biomarkers of periodontal disease progression. The study aims to identify factors that indicate susceptibility to developing periodontal disease and design more specific treatments.
Researchers at the University of Alberta found that omega-3 fatty acid DHA in fish prevented toxic buildup in the retina, a common cause of age-related vision loss. The discovery could lead to a therapeutic use for supplementing the diet with DHA.
Researchers found that a specific gene, CCR2, associated with immune activity is linked to memory and cognitive function in people. This discovery could lead to new approaches to slowing or preventing Alzheimer's disease.
A study published in the Journal of Clinical Periodontology concludes that a two-step tooth implantation method is more effective than a one-step process. The research found that implants placed using the two-step procedure show less wear and tear over time, with greater bone stability.
A study found that ACE2 is protective against diabetic complications in both lab models and human patients. High levels of ACE2 in vascular reparative cells prevent heart function decline and renal failure in diabetics.
Research at Peninsula College of Medicine and Dentistry found that screening people with type 2 diabetes every two years is a safe and cost-effective strategy, reducing costs by around 25%. This approach could benefit 2.8m people in the UK who have diabetes.
A study by the Academy of General Dentistry found that sports and energy drinks cause irreversible damage to teeth due to high acidity levels. Energy drinks are twice as likely to destroy enamel than sports drinks.
Researchers at NYU College of Dentistry and UCSF will use genomic markers to identify oral cancer patients who don't need neck dissection. This study aims to improve quality of life and reduce recovery time for patients, potentially saving lives.
Researchers propose a new classification of severe early childhood caries, which affects mostly young children living at or below poverty levels. The condition is characterized by structurally damaged primary teeth and is linked to developmental dental defects such as enamel hypoplasia.