Researchers at IBS discover sequence-dependent information influences liquid-liquid phase separation. Single-stranded DNA forms droplets easily, while double-stranded DNA requires specific conditions due to its rigid structure.
Researchers have discovered a new class of 2D magnetic materials with promising applications in electronics. These ultra-thin layers exhibit unique properties, such as ferromagnetism, antiferromagnetism, and magnetism control, which can be manipulated electrically or optically.
A research group at IBS invents contact-free annealing technique to convert polycrystalline metal foils into single crystals with superior properties. They successfully produced large single crystal metals up to 32 cm2, including copper, nickel, cobalt, platinum, and palladium.
Researchers have made a major scientific breakthrough by detecting nuclear magnetism in single atoms on surfaces for the first time. The discovery uses advanced techniques to measure the nuclear spin of individual atoms, enabling identification of different isotopes atom by atom.
Researchers at IBS have developed a new method to generate extreme-ultraviolet emissions, opening doors for high-resolution imaging, ultrafast spectroscopy, and next-generation lithography. By controlling electron motion using laser pulses, they created coherent radiation with specific wavelengths.
Researchers developed a wearable and implantable device that measures electrophysiological signals and applies electrical and thermal stimulations. It was successfully used on a human wrist to monitor the electrical activity of heart and muscles.
Researchers found that plant's daily oscillatory clock interacts with the aging linear clock during their lifetime, influencing leaf yellowing timing. The study identified key genes, such as PRR9, involved in this interaction.
Scientists at IBS report a breakthrough using heavy water (D2O) to delay sample damage in transmission electron microscopy. The approach allows for longer observation of molecule movements, enabling study of the nanoworld.
Ceria nanoparticles selectively remove reactive oxygen species from mitochondria, intracellular and extracellular spaces, improving Parkinson's disease symptoms in mice. Lowering oxidative stress in these compartments is crucial for treating the disease.
A new study reveals that El Niño diversity arises from the interaction between Eastern and Central Pacific oscillations, leading to irregular occurrence and complex behavior. This understanding is crucial for predicting El Niño events accurately in a warming world.
Biologists identify how mixed nucleotide tails in mRNA delay its shortening, acting as a shield against premature degradation. This discovery could bring new insights into gene regulation and potential RNA-based gene therapy methods.
Researchers at the Institute for Basic Science discovered that asymmetric apertures can cause astigmatism in microscopes, leading to degraded image resolution. By correcting for this effect, they improved the technique of line-temporal focusing microscopy, achieving unprecedented resolution in biological structures.
At temperatures near absolute zero, systems of atoms violate basic laws of statistical mechanics and thermodynamics. A novel non-equilibrium state, coined as dynamical glass phase, is observed where energy is not evenly distributed, leading to a new understanding of complex systems.
A team of researchers has developed a model that simulates protein evolution, revealing how evolving protein components can give rise to dynamic and efficient molecular machines. The model shows that flexibility allows proteins to bind effectively to other molecules.
A team of researchers at the Institute for Basic Science developed a new method to measure laser pulse shapes in ambient air. The patented technique, TIPTOE, uses tunnel ionization and achieves temporal characterization of laser pulses without X-ray pulses or vacuum conditions.
Researchers at the Center for Multidimensional Carbon Materials successfully measured and controlled the temperature of individual graphene bubbles using a single laser beam. The study found that the temperature oscillates with bubble height, allowing for efficient heating of specific regions within the bubble.
Researchers discovered that plants create a molecular brace composed of lignin in the detachment zone to facilitate precise shedding. Additionally, they form a protective coating made of cutin on newly exposed cell surfaces, preventing infection and external harm.
Researchers identified a gene variant linked to increased empathic fear in mice, which may contribute to individual variability in neuropsychiatric conditions. The study found that the variant affects neurons in the cerebral cortex, leading to heightened observational fear response.
Researchers have developed a novel technique that enables them to visualize biological targets in deep tissues without damaging tissues or labeling with fluorescent molecules. The method, which uses selectively guided light waves, overcomes the limitations of current optical imaging techniques.
Researchers developed light-responsive vesicles that can deliver anticancer drugs at precise timing and location. The technology uses a near-infrared laser to break the vesicles apart, releasing the drug only in targeted areas, reducing damage to healthy tissue.
A team of researchers has developed a novel reaction to insert nitrogen into C-H bonds, creating useful ring-shaped molecules. The breakthrough synthesis uses inexpensive feedstock hydrocarbons as substrates, offering a new solution to the long-standing challenge in pharmaceutical and chemical industries.
Researchers developed a technique to visualize mitophagy, the process by which cells recycle their energy factories, with a new bioimaging technology. The study could provide diagnostic information for degenerative brain diseases.
Scientists at the Institute for Basic Science have made a major breakthrough in controlling the quantum properties of individual atoms. They used advanced methods to image and measure individual iron atoms, finding that nearby electrons destroy their quantum behavior.
A team of researchers developed a fluorescent sensor, TiY, that selectively stains tumor initiating cells (TICs) in various cancer tissues. The sensor can distinguish TICs from non-TICs and inhibit sphere formation, leading to suppressed tumor growth in mice xenograft models.
Researchers developed a low-temperature reaction to replace sulfur with tellurium in MoS2, creating new properties in the 2D material. The 'sodium-scooter' catalyst enables conversion at 525°C, lower than previous temperatures.
Scientists have developed a multiresponsive nanosurfactant that can manipulate liquid droplets using magnetic fields, electric fields, and light. The droplets can be assembled into complex structures and mixed to create chemical reactions.
Researchers develop novel method for selective C-H arylation at room temperature, overcoming harsh reaction conditions. The proposed mechanism involves iridium catalyst activation, arylsilane attack, and oxidation of the intermediate to achieve low-energy reaction.
Researchers discovered that defects in monolayer molybdenum disulfide (MoS2) exhibit electrical switching, providing new insights into the material's electrical properties. This finding could contribute to MoS2's future use in opto-electronics and address current limitations.
Researchers found that bacteria navigate randomly but are biased towards nutrient sources, unlike enzymes which move towards areas with less substrate. The study used super-resolution microscopy and discovered run-and-tumble dynamics in enzyme motion.
Researchers from the Institute for Basic Science synthesized four new kinds of stabilized radicals with ferromagnetic properties, opening doors to applications in rechargeable batteries and molecular spintronics. The oxime radicals were stabilized using N-heterocyclic carbenes, a breakthrough in synthesizing organic radicals.
Researchers have developed ultra-thin and flat graphene metalenses that can concentrate terahertz beams to a spot, flip their polarization and modulate their intensity. These devices have the potential to revolutionize applications such as amplitude tunable lenses, lasers and dynamic holography.
Researchers at Institute for Basic Science developed a method to create dynamic tubular structures by exploiting centripetal force of rotating fluids, enabling self-assembly of particles under non-equilibrium conditions. This breakthrough could lead to creation of various shapes of microcomposites useful in photonics applications.
A study by IBS scientists found that mice develop 'social rules' to allocate rewards, promoting long-term benefits for both mice. The researchers used brain stimulation to induce a sense of pleasure, and observed that 60% of the mice waited for their turn, leading to more rounds and total reward time.
Scientists developed a hydrogel that detects nitric oxide and absorbs excess fluids, delivering drugs to treat rheumatoid arthritis. The gel uses acrylamide as a base material and NOCCL crosslinker to trap drug molecules.
Scientists have developed a new sensor that can detect minute concentrations of methamphetamine and amphetamine in urine, allowing for real-time drug screening. The sensor uses a pumpkin-shaped molecule to bind with the drugs, triggering an electrical signal that appears on a smartphone screen.
Researchers at IBS Institute for Basic Science observed polymers in liquid inside graphene pockets without staining, revealing their dynamic movement. The study paves the way for observing life's building blocks and self-assembly of materials.
Researchers at IBS developed first 2D field-effect transistor made of single material, overcoming efficiency limits of current 3D transistors. The new technique uses a polymorphic material, molybdenum telluride (MoTe2), to produce both metal and semiconductor components with low contact resistance.
Researchers at IBS have identified a new mechanism involved in glaucoma development and progression, and found a potential therapeutic option to treat primary open-angle glaucoma. The study highlights the critical role of the angiopoietin-Tie2 system in Schlemm's canal functionality.
Researchers at IBS and KAIST found that YAP/TAZ promotes cytoskeleton remodeling and junction formation in endothelial cells, essential for normal as well as pathological angiogenesis. Overexpression of YAP/TAZ leads to excessive blood vessel growth, while removal results in vision impairment and internal bleeding.
Scientists at IBS conceptualized an ideal material that could store data for an exceptionally long time, bringing new hints for future quantum memory technologies. The material has a special architecture of energy levels for its electrons, enabling exponentially longer storage than current devices.
Scientists successfully corrected a disease-causing mutation in human embryos using CRISPR-Cas9, increasing the probability of inheriting a healthy gene from 50% to 72.4%. The technique also revealed an alternative DNA repair system in human embryos.
Researchers developed a new non-toxic contrast agent for magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA), surpassing gadolinium's limitations. The agent, PEG-IONCs, demonstrated high biocompatibility in rabbits, beagle dogs, and macaque monkeys, showing promise as a next-generation diagnostic tool.
A new study reveals that the Atlantic and Pacific ocean temperatures play a significant role in droughts and wildfires in southwestern North America. The research shows that the large-scale difference between the two oceans enhances the risk for drought and wildfire in the region.
A recent study reveals that innate lymphoid cells (ILCs) compete with T cells for a shared source of interleukin-7 (IL-7), a protein essential for their survival. This competition sheds light on the complex phenomenon of homeostasis, which supports the long-term survival of immune cells.
Researchers have successfully grown large sheets of monolayer single-crystal graphene, overcoming technical challenges to achieve a 5 x 50 cm2 sheet in just 20 minutes. The low-cost method has the potential to expand graphene's usability and enable its use in flexible circuits.
Researchers developed a nanoparticle-based adhesive that exhibits imaging contrast effect in CT and ultrasound, is biocompatible, and ensures accurate target localization during movement. The new glue has shown less toxicity than FDA-approved options and was successfully tested in animal models for various surgical procedures.
Researchers developed ceria-zirconia nanoparticles to treat sepsis by removing harmful oxygen radicals and reducing inflammatory responses. The nanoparticles improved survival rates by 2.5 fold in mice with sepsis, offering a new therapeutic strategy for this deadly disease.
Researchers at the Institute for Basic Science used optogenetics to manipulate thalamic spindles in mice, affecting their ability to recall memories. The study found that artificial spindles administered at specific timing enhanced memory consolidation, while reduced spindles impaired recall.
Researchers from IBS Center for Geometry and Physics introduce a new mathematical operation to catalog Legendrian singular knots, crucial for understanding complex 3D spaces like our universe. The study aims to explore the fascinating possibilities of 3D spaces and provide a tentative list of all possible shapes.
Scientists have discovered a cheap and efficient way to produce olefins, the chemical feedstock for many products, using a titanium-based catalyst. The reaction can be performed at low temperature and has the potential to reduce greenhouse gas emissions and costs associated with traditional fossil fuel-based methods.