The study reveals that lysine residues in the RNA polymerase act as a 'bucket brigade', transporting drugs and nucleotides to the binding site through electrostatic interactions. Favipiravir is found to be taken up more efficiently than ATP, while remdesivir outperforms favipiravir.
Researchers analyze Plakobranchus ocellatus type black sea slug genome, finding chloroplasts retain photosynthetic capability for months. The study reveals no evidence of algal genes encoded on the sea slug genome, suggesting alternative mechanisms behind kleptoplasty.
Researchers have developed a new radio receiver capable of capturing radio waves at frequencies several times wider than conventional ones. This allows for the detection of multiple types of molecules in space simultaneously, enabling significant progress in studying the evolution of the Universe and star formation.
A new study found a low rate of lithium production in a classical nova, indicating diversity within these events. This discovery suggests that other objects, such as supernovae, may also contribute to lithium production in the Universe.
Researchers have engineered an enzyme to bind to and degrade plastic particles, potentially helping to resolve the issue of complete recycling of PET in industry. The enzyme, called PET2, was found to accelerate the reaction between PET's chemical components and water when positive charges were introduced on its surface.
Japanese astronomers developed an AI technique to remove noise in galaxy shapes caused by random variations. The new tool was applied to actual data from Japan's Subaru Telescope and found consistent results with accepted models of the Universe.
A team of researchers identified the design principles for creating large ideal proteins, paving the way for designing proteins with new biochemical functions. They found that while designed proteins are structurally ideal, they lack functional sites due to internal energetic frustration.
Researchers used ALMA to detect a galactic wind driven by a supermassive black hole 13.1 billion years ago, pushing back the start of galaxy-growth interactions by 100 million years. The observation reveals coevolution between supermassive black holes and galaxies since less than a billion years after the Universe's birth.
Researchers at National Institutes of Natural Sciences have developed an Advanced Multi-Step Brazing (AMSB) technique to jointly fabricate components made of oxide dispersion strengthened copper alloy. The new technique enables the creation of a heat removal component with excellent heat removal performance, surpassing existing records.
Researchers discovered a galaxy with a spiral structure 1.4 billion years after the Big Bang using ALMA data. The galaxy's estimated mass is roughly equal to that of the Milky Way and contains a large amount of dust, making it difficult to study in visible light.
Researchers develop a new technique to investigate surface structures of semiconductors at the atomic scale. The technique, called atomic point contact Raman spectroscopy, reveals enhanced Raman scattering from silicon surfaces when a plasmonic silver tip is brought into contact with the surface.
Astronomers have developed a new tool to investigate the structure of invisible inter-cluster magnetic fields in galaxies. The technique uses jets of high-energy particles emitted from massive black holes to create detailed maps of these magnetic fields.
Astronomers used ALMA to discover a rotating baby galaxy, providing insights into the early Universe. The galaxy, RXCJ0600-z6, is about 1/100th the size of the Milky Way and has a mass of 2-3 billion times that of our Sun.
A survey of star formation in the Orion Nebula Cluster found similar mass distributions for newborn stars and dense gas cores, suggesting that gas accretion rate determines final star mass. The results contradict the core-collapse model, supporting the competitive accretion model instead.
L-DOPA-induced dyskinesia is a major side effect of long-term medication, affecting millions worldwide. Researchers revealed the link between neuronal activity changes and dyskinesia, suggesting suppressing or restoring neurotransmission through key pathways may improve symptoms.
Researchers discovered a 800-meter diameter comet nucleus with large grains of phyllosilicate, similar to talcum powder, and evidence of organic molecules. The team used the Subaru Telescope to observe thermal infrared radiation, indicating the surface temperature had reached over 330 degrees Celsius in the past.
Scientists at Japan's National Institutes of Natural Sciences have successfully synthesized zigzag nanotubes using a novel method. This breakthrough enables the controlled production of all three types of nanotubes: armchair, chiral, and zigzag.
Researchers have successfully developed the first stable and strong self-assembling nanographene wires using 3D design. The team created a molecule called 'bitten' warped nanographene (bWNG) that can assemble into double-stranded, double-helix nanofibers.
A team of scientists at the National Institutes of Natural Sciences has successfully developed a broadband mid-infrared (MIR) source with high beam quality, enabling simplified environmental monitoring systems. The MIR source facilitates industrial and medical applications, including gas detection and breath analysis.
Astronomers discovered over 800 dense gas and dust cores near the Galactic Center, which may be 'stellar eggs' hatching into baby stars despite harsh conditions. The findings suggest that star formation is more resilient than thought, with ALMA observations detecting small outflows indicative of star birth.
Scientists have created a new type of salt that acts as an electrical conductor, exhibiting unique magnetic coordination at low temperatures. The discovery was made using tetrathiafulvalene as a skeleton for the new substance, which has infinite chain structure and stabilizes atomic arrangements.
Researchers have successfully tracked the ultrafast motion of electrons inside a Xenon atom using synchrotron radiation. By interfering with the coherent light waves, they observed the electron movement at a time scale of femtoseconds, significantly faster than previously thought.
Scientists from Japan's Institute for Molecular Science have created a new recipe for stable radical-based coordination polymers, which have potential applications in electronics and spintronics. The materials exhibit photoluminescence properties and can be produced using different metal ions or complexes.
Researchers successfully grow mouse stem cells into sperm in the body of rats, paving the way for efficient reproduction and future applications.
The CLASP2 sounding rocket experiment charted the magnetic field strength all the way up to the top of the chromosphere, a long-sought goal. This breakthrough brings scientists closer to understanding how magnetic fields heat the solar corona.
A team led by Masato Shirasaki applied a reconstruction method to turn back the cosmic clock and remove gravitational effects from simulated universes. They found that their method can correct for gravitational effects and improve constraints on primordial density fluctuations.
Scientists have developed a light-activated protein that can study single synapses in neurons, revolutionizing the understanding of long-term potentiation. The discovery reveals the physical changes in dendritic spines during long-term potentiation, providing valuable insights into learning and memory.
A scanning transmission X-ray microscope for lithium analysis has been developed, enabling the study of chemical states and behaviors with high spatial resolution. The microscope uses a low-pass filtering zone plate to suppress higher-order harmonics, allowing for accurate measurement of XAS spectra.
Researchers discovered that MpSYP12B redirects the secretory pathway to form the liverwort oil body, providing strong empirical support for the organelle paralogy hypothesis. The oil body accumulates compounds with bioactivities, including antibacterial and anticancer properties.
Simulations reveal that longitudinal fluctuations preferentially mix with ions, leaving electrons cooler, while transverse fluctuations can mix with both. This finding has significant implications for understanding astronomical observations of supermassive black holes.
Researchers discovered that backbone structure is key to lab-made protein thermostability, contradicting earlier assumptions about hydrophobic core packing. This breakthrough opens doors to designing even more stable proteins for various industries.
A new study using VERA data has revised Earth's velocity around the Galactic Center from 220 km/s to 227 km/s, making it faster. The revised calculation places Earth approximately 2000 light-years closer to the supermassive black hole at the Galaxy's center.
Researchers found that coral larvae temporarily stop swimming due to reduced light intensity and then resume swimming at their initial speed. This behavior may play a role in determining where corals settle, with the larvae gathering in bright spaces.
A recent brain study by Masaki Isoda and colleagues found that a specific connection between two regions in the front of the brain allows monkeys to correctly interpret social cues. This ability requires the PMv-mPFC pathway, which enables monkeys to differentiate between accidental mistakes and rule changes.
Research reveals basal ganglia neurons primarily use firing rate changes to control voluntary movements, with synchronized activity having a minor role in healthy conditions. Parkinson's disease symptoms may be improved by targeting abnormally increased correlated activity in the basal ganglia.
A team of astronomers studied sunspots to characterize star conditions, which is crucial for finding exoplanets. The research aimed to create a single emission profile similar to other stars, allowing astronomers to identify dimming caused by exoplanet shadows.
Researchers from Japan's Institute for Molecular Science have described a bacterial cellulose degradation system in detail, revealing its similarities and differences with the fungal system. The study found that the bacterial system exhibits higher processivity, enabling faster cellulose degradation.
Research team successfully visualized intracellular calcium concentrations in the Venus flytrap, revealing that its short-term memory can be explained by changes in calcium concentration. The study demonstrates how a single contact event triggers a burst of calcium ions, which then trigger a second stimulus to close the trap.
A study of comet motions reveals a second alignment plane in our solar system, dubbed the 'empty ecliptic.' The newly discovered plane is where comets' farthest points (aphelia) tend to converge, challenging models of Solar System formation. Long-period comets' orbits show two peaks near the well-known ecliptic and empty ecliptic planes.
The team discovered two massive young stars shrouded by gaseous disks containing sodium chloride and heated water vapor. The disks are counter-rotating, indicating the pair may not be twins, but rather strangers formed in separate clouds.
An international team of astronomers detected phosphine in Venus' atmosphere, which could be evidence of biological origin, but unknown photochemistry or geochemistry are also possible explanations.
Researchers discovered a new link between arginine metabolism and plant shape formation, using the moss Physcomitrium patens as a model organism. The study identified a core pathway involving transcriptional co-activators ANGUSTIFOLIA3/GRF-INTERACTING FACTOR1 (AN3/GIF1) family signaling.
Scientists have successfully moved electrons in an organic superconductor by irradiation of ultrashort laser pulses, generating a polarized net current. The observed effect is attributed to scattering-free current, sensitive to superconducting fluctuations, with potential applications in ultra-fast computing and understanding microscop...
Researchers found three large, misaligned dust rings around the young triple star system GW Ori, with sufficient dust for planet formation. A computer simulation suggests that a hidden planet may have carved out a dust gap and broken the disk at the location of the current inner and outer rings.
The discovery of radio jets in the Phoenix Galaxy Cluster suggests that a supermassive black hole is actively heating intra-cluster gas, preventing star formation. This finding has significant implications for our understanding of galaxy evolution and coevolution.
Researchers discovered that DNA damage in moss Physcomitrella patens causes cells to reprogram into stem cells, producing an entire plant body. This phenomenon is a new adaptive strategy for plants under harsh environments.
Astronomers used AI to classify spiral galaxies in Subaru Telescope images, achieving 97.5% accuracy and identifying 80,000 galaxies.
Researchers tracked the evolution of stellar eggs in Taurus, discovering internal structures and bipolar gas streams that indicate a star's birth. The team used ALMA's compact array to observe starless cores and found evidence for 'first hydrostatic cores,' short-lived objects formed before a baby star's birth.
A team of researchers has developed a computational model to describe the motion of molecular motors, shedding light on how they generate unidirectional motion. The study found that molecular motors follow a
Astronomers used machine learning to discover a rare galaxy with an oxygen abundance of 1.6% solar levels, setting a new record. The galaxy is thought to be in its early stages of formation, contradicting standard cosmology predictions.