A team of researchers from Peking University's College of Future Technology has identified a DddA homolog from Simiaoa sunii that can efficiently deaminate cytosine in double-stranded DNA. This discovery expands the sequence compatibility of mitochondrial base editors, enabling efficient and highly specific editing.
A study by Peking University reveals that late canopy development in Northern ecosystems delays seasonal peak photosynthesis. The mismatch in timing between the two has significant implications for understanding carbon sequestration in these regions.
Researchers using FAST telescope discover complex, magnetized environment around FRB 20201124A, contradicting young magnetar engine theories. The team analyzed 1863 bursts of the source, revealing irregular variations and circular polarization.
Peng Hailin's group reports a novel dielectric material, β-Bi2SeO5, with excellent insulativity and high dielectric constant. The ultrathin single-crystalline dielectric can be scaled down to an EOT of 0.41 nm in two-dimensional field-effect transistors, meeting the requirements of the International Roadmap for Devices and Systems.
A recent study by Luo Dong-Gen and his team found that the master circadian clock relies on xCEO neurons to generate timekeeping of behavior rhythms. This finding suggests that timekeeping may be a core mechanism of the circadian clock in both insects and mammals.
Fused-ring electron acceptors (FREAs) have revolutionized the field of organic solar cells, achieving unprecedented efficiencies over 20% and potential operational lifetimes approaching 10 years. The properties of FREAs can be modulated through variations to their electronic structure or molecular packing.
A research team at Peking University developed SMOOTH-seq technology for sequencing single-cell genomes on third-generation sequencing platforms. They successfully assembled human genomes from just several individual cells, achieving megabase level contig N50 contigs.
Researchers at Peking University discovered a plant immune protein, RDR1, that can repair microRNA defects in cancer cells, leading to broad-spectrum anti-tumor response. The study provides a new strategy for tumor treatment and makes RDR1 a powerful weapon against cancer.
Scientists successfully visualize the atomic structures of stable Eigen/Zundel cations on metal surfaces using qPlus-based AFM, PIMD simulations and DFT calculations. They reveal a new proton transfer mechanism at water-solid interfaces involving the conversion from Eigen to Zundel cations.
A collaborative paper by Wang Yicheng and colleagues finds that households reduce risky shares of assets when income risk doubles, with potential social welfare gains of 4% if policies stabilize income risk. The study also examines the effect of progressive income tax systems on financial portfolio choices.
A study of 264 studies in 53 countries found that natural forests better support biodiversity and ecosystem services like carbon storage and water conservation. In contrast, plantations excel in wood production, highlighting a trade-off between environmental and economic goals in forest restoration.
Researchers visualize ethylene polymerization on ordered iron carbide surface using in situ technology, revealing molecular insertion mechanism and chain initiation process. The study clarifies the scientific debate regarding chain initiation over Phillips catalysts and provides a method for controlling product chain length distribution.
A panel study in Beijing found a consistent, robust increase in fasting blood glucose levels after exposure to ultrafine particles (UFPs). The research suggests potential biological pathways, including pro-opiomelanocortin processing and regulation of hypoxia-inducible factor 1 A function.
A joint research team from Peking University developed a fine-scale library of pH-sensitive polymeric nanoprobes to accurately measure acidification levels of virus-infected cell membranes or viral envelopes. The polymer, GPS6.8, has broad-spectrum and efficient antiviral effects.
A research group led by Ryuichi Shindou proposes a new phenomenon where magnetic spin and electric charge are converted without energy loss in emergent superfluids of 2D materials. This conversion is made possible by exciton condensates, which exhibit dissipationless supercurrent flows.
A team of researchers proposed a novel approach to spintronics, demonstrating dissipationless conversion between magnetic spin and electric charge in an emergent superfluid in 2D materials. This breakthrough could lead to the development of more efficient spintronic devices.
Researchers at Peking University developed a microsensor that leverages whispering gallery modes to detect single DNA molecules with improved sensitivity. The interface mode outperforms traditional evanescent field-based sensors, offering ultra-small sample consumption and automatic analysis capabilities.
Researchers found dominant species in coastal sediments are copiotrophs with high growth rates, while those in ocean water are oligotrophs with low growth rates. The 'Hunger Games' hypothesis explains how nutrient supply influences microbial interactions and community structure.
Researchers at Peking University created a comprehensive single-cell landscape of tumor-infiltrating T cells across 21 cancer types, revealing heterogeneity and dynamics. This study provides an immune-typing scheme that could inform targeted therapy.
The Li Faxin Research Group at Peking University has developed the world's first dynamic mechanical analyzer (DMA) suitable for hard materials. This instrument measures Young's modulus, shear modulus, and internal friction under variable temperature conditions, offering accurate and quick analysis of material properties.
The study evaluated outcomes of minimally invasive esophagectomy compared to open esophagectomy in 6000 ESCC patients over 10 years. MIE was found to be an effective treatment option even for large tumors, expanding its indicated population.
Researchers identified two novel mutations in the LRP6 gene associated with a rare form of hand polydactyly and tooth agenesis. The study expands the genetic spectrum of LRP6-related disorders, enabling clinicians to differentiate diagnosis and facilitate genetic research.
Researchers from Peking University developed a new technique using 4D-EELS to measure phonon modes at heterointerfaces, directly observing localized phonon modes for the first time. This breakthrough enables better understanding and control of solid interfaces' properties.
Scientists harness higher-order protein catenation to create complexed proteins with potential as artificial antibodies. The new method enables the synthesis of protein [n]catenanes, which show improved binding affinity and prolonged serum half-life.
PKU researchers harness higher order protein catenation to create complexed topological proteins, leading to the synthesis of artificial antibodies with enhanced affinity and prolonged serum half-life. The study successfully expands toolkits for protein entangling motifs, promoting advanced protein therapeutics.
Researchers at Peking University developed a non-invasive exhaled breath screening system for COVID-19, identifying key breath-borne VOC biomarkers in just 5-10 minutes. The technology reduces transmission risk by providing quick screenings for false negatives and hospital discharges.
A new study maps global cropland nitrous oxide emissions and finds that reducing fertilizer application over 20% of the world's croplands could achieve 65% of global mitigation potential. The research identifies hotspots of high emissions in humid subtropical regions, where climate and soil characteristics play a significant role.
Researchers developed a scanning quantum sensing microscope that maps local electric fields with a spatial resolution of ~10 nm and sensitivity close to an elementary charge. The technique allows for reversible control of single NV's charge states, enabling the purification of NV's electrostatic environment.
Scientists found a metal-insulator transition in 2H-MoTe2 by enhancing electron-phonon coupling at the surface. The experiment shows strong interaction of electrons and lattice excitations, forming polarons that localize and drive the observed phase transition.
A recent study synthesizes global dryland aridity changes, revealing a complex interplay between atmospheric drying and ecosystem greening. Despite rising aridity, lusher drylands are observed due to the physiological response of plants to increasing CO2 concentrations, which conserves water and promotes plant growth.
Zhan Xiaowei's group has developed a new class of molecular design strategies for fused-ring electron acceptors (FREAs), leading to unprecedented breakthroughs in organic solar cells. The discovery has surpassed fullerenes in performance and opened up new applications in perovskite solar cells, quantum dot solar cells, and more.
Researchers at Peking University have discovered a simple rule explaining how fish save energy by interacting with vortices shed by neighbors. The study was conducted using high-fidelity robotic fish and verified in real fish, suggesting the universal adoption of this mechanism in biological systems.
Researchers at Peking University discovered a new type of superconductor that remains stable in ambient conditions, exhibiting large critical magnetic fields and strong spin-orbit coupling. This macro-size system with out-of-plane spin polarization has great potential for superconducting electronic and spintronic applications.
An international team has successfully mapped the global distribution of the coronal magnetic field for the first time. Using observations from the Coronal Multi-channel Polarimeter, they applied a technique called magnetoseismology to infer the average magnitudes of the magnetic field in the corona.
Researchers simulated a 3D chiral topological insulator using nitrogen-vacancy centers, observing dynamical bulk-surface correspondence and symmetry protection in momentum space. They measured spin textures on band inversion surfaces, revealing perfect (broken) topology depending on the preserved or broken chiral symmetry.
Researchers elucidate a global picture of edge states in Weyl semimetals, revealing how they form closed trajectories under tilted magnetic fields. The study provides new understanding of the three-dimensional quantum Hall effect and its relation to topological properties.
Researchers have discovered high-Chern-number and high-temperature Chern insulator states in MnBi2Te4 devices, exhibiting multiple dissipationless edge states above liquid helium temperature. Theoretical calculations reveal the origin of these states as a magnetic Weyl semimetal with layer-dependent Chern number.
A joint research team led by Sunney Xie has identified multiple highly potent neutralizing antibodies against SARS-CoV-2 from convalescent plasma. These antibodies provide a potential cure for COVID-19 and offer short-term prevention, marking a major milestone in the fight against the pandemic.
Researchers have developed a novel MRI compatible graphene fiber DBS electrode, enabling full activation pattern mapping by simultaneous deep brain stimulation and fMRI. This breakthrough showed a close relationship between fMRI activation and DBS therapeutic improvement in Parkinsonian rat models.
Researchers at Peking University developed a new fluorinated fused-ring electron acceptor with 3D stacking and exciton and charge transport, leading to improved efficiency in organic solar cells. The OSCs based on FINIC showed an efficiency of 14.0%, significantly higher than nonfluorinated INIC-based cells.
A new study reveals that China's water use has been decelerating since the 1970s, thanks to the adoption of water-conserving technologies. The study found that irrigation and industrial water recycling drove this reduction, offsetting the increase in water use driven by economic growth.
At 2-dimensional limit, researchers at Peking University detect novel zero-energy bound states resembling Majorana zero-energy bound states in interstitial Fe adatoms on high-temperature superconducting thin films. These findings exhibit characteristics of Majorana zero mode, a potential building block for topological qubit.
Scientists at Peking University have discovered Majorana zero modes (MZMs) at both ends of 1D atomic line defects in iron-based high-temperature superconductors. The MZMs exhibit robust properties and can be detected using scanning tunneling microscopy/spectroscopy, offering a promising platform for topological quantum computing.
Scientists demonstrate a reconfigurable chiral microlaser in a symmetric WGM microcavity, achieving unprecedented control over laser directionality and chirality. The device exploits the optical Kerr nonlinearity to break symmetry spontaneously, enabling all-optical control of chirality.
Researchers found a stable liquid-gas interface on the Salvinia leaf, enabling drag reduction and anti-corrosion properties. Biomimetic artificial surfaces replicated this effect using 3D printing technology.