The study reveals age-related changes in lipid metabolism, including increased BMP-type lipids in kidneys and liver, and sex-specific differences in galactosylceramide levels. These findings may lead to better understanding of chronic diseases and the development of targeted treatments.
Researchers created an 'optical conveyor belt' to control polariton energy landscape, achieving non-reciprocity and topological phase of matter. This technology has potential applications in quantum metrology, quantum information and opto-electronic devices.
Researchers at RIKEN have developed a new catalyst that reduces the amount of iridium required for hydrogen production, achieving 82% efficiency and sustaining production for over 4 months. The breakthrough could revolutionize ecologically friendly hydrogen production and pave the way for a carbon-neutral energy economy.
The research group found that the Japanese population can be divided into three clusters, with different concentrations in Okinawa, Northeastern Japan, and Western Japan. They also identified genetic variants associated with hereditary breast cancer and provided insights into gene sequences derived from Neanderthals and Denisovans.
Scientists have discovered a rule governing the phenomenon of quantum entanglement, known as the 'entropy' of entanglement. This finding could lead to better understanding and manipulation of quantum entanglement, a key resource for future quantum computers.
Researchers at RIKEN have improved the stability of a green hydrogen production process by using a custom-made catalyst, increasing its lifetime by almost 4,000 times. The breakthrough uses earth-abundant materials, making it more sustainable and potentially cost-effective for widespread industrial use.
Researchers have discovered a greener way to produce ammonia, essential for fertilizers, by developing a new catalyst that works stably at relatively low temperatures. This breakthrough reduces the amount of energy needed to synthesize ammonia, making it an attractive alternative to fossil fuels.
Researchers at RIKEN Center for Brain Science discovered neural circuitry in the spinal cord that enables brain-independent motor learning and recall. The study found two critical groups of neurons: one necessary for new adaptive learning and another for recalling adaptations once learned.
Researchers have developed an organic photovoltaic film that is both waterproof and flexible, enabling a solar cell to be used on clothes without compromising performance. The breakthrough film retained up to 96% of its initial performance after being submerged in water or stretched beyond its limit.
Researchers have solved the long-standing question of what triggers the alarm response in fish by identifying two distinct chemical signals: Daniol sulphate and Ostariopterin. These substances convey separate pieces of information that must be detected simultaneously to trigger a flight-or-freeze response.
Researchers at RIKEN found that gut bacteria, particularly Bifidobacterium, are associated with higher chances of successful milk-allergy treatment. However, only 7 out of 28 children who underwent oral immunotherapy passed the food challenge after a two-week milk avoidance period.
A research team developed a model of the blood-brain barrier using modularized tissue derived from human cells. The 'Tissue-in-a-CUBE' system accurately mimics the real blood-brain barrier in terms of structure and function, allowing for the testing of drugs without animal testing.
Researchers at RIKEN CSRS have created a self-healing material that can emit high levels of fluorescence when absorbing light, leading to improved durability for organic solar cells. The material's unique structure allows it to self-repair without external stimuli or energy, making it suitable for various environments.
Researchers have discovered that plant immune receptors and growth-related proteins share a common evolutionary ancestry, allowing for the creation of hybrid receptors with enhanced functionality. This breakthrough could lead to the development of disease-resistant crops by isolating and engineering immune receptors from various plants.
Researchers discovered that de novo mutations in promoter regions of TADs containing known ASD genes are associated with increased ASD risk due to interactions in the three-dimensional structure of the genome. This 'butterfly effect' explains how mutations can affect distant ASD-related genes, highlighting the need for a new diagnostic...
Researchers at RIKEN successfully spin artificial spider silk that closely matches natural production, mimicking the complex molecular structure of silk. The eco-friendly innovation has potential benefits for environment and biomedical fields.
Researchers from RIKEN have successfully created transformations between skyrmions and antiskyrmions using heat gradients at room temperature. This breakthrough could lead to the development of next-generation memory devices with low energy consumption, utilizing waste heat.
Researchers have developed a solid electrolyte that allows for efficient hydride ion conduction at room temperature, enabling the creation of safer, more efficient hydrogen-based batteries and fuel cells. This breakthrough provides material design guidelines for the development of next-generation energy storage solutions.
Researchers discovered that parasites like horsehair worms use stolen genes to control host behavior. They found over 3,000 genes expressed more in manipulated hosts, suggesting the parasite produces its own proteins for manipulating nervous systems.
A new laser-based sampling system allows for higher depth resolution, enabling scientists to reconstruct continuous annual temperature changes thousands of years ago. The LMS system overcomes previous limitations in sampling ice cores, preserving critical oxygen and hydrogen isotopes needed to infer past temperatures.
A team of scientists has discovered a more accurate pressure scale using synchrotron studies, leading to a significant increase in the amount of light material in the inner core. The new scale found double the expected amount of lighter material in the inner core and five times that of the Earth's crust.
Researchers from RIKEN Center for Quantum Computing have used machine learning to perform efficient quantum error correction using an autonomous system that can determine the best corrections despite being approximate. Machine learning plays a crucial role in addressing large-scale quantum computation and optimization challenges.
Researchers discovered a gut bacteria that helps reduce insulin resistance and protect against diabetes. The study found that a specific bacteria, Alistipes indistinctus, consumed excess monosaccharides in the gut, lowering blood sugar levels and reducing insulin resistance.
Researchers have found that mouse stem cells mimic their parent animals' cold resistance, generating energy differently at low temperatures. This discovery opens up new avenues for studying organ preservation and human hibernation using in vitro models.
Researchers used a mathematical theory called the free energy principle to predict how real neural networks learn and organize themselves. The study successfully mimicked this process in rat embryo neurons grown in a culture dish, demonstrating the principle's guiding force behind biological neural network learning.
Researchers have discovered a new way to combat fatal fungal infections by blocking the production of fatty acids, a major component of fats. The breakthrough could lead to more effective treatments against species-resistant fungi.
Researchers at RIKEN CEMS have discovered a perovskite compound that can safely store corrosive ammonia gas as a nitrogen compound, allowing for efficient storage and retrieval of hydrogen. The process is much cheaper than traditional methods and can be repeated multiple times.
Researchers have developed a new technique to generically treat several kinds of cancer, showing tumors grew almost three times less and survival rates reached 100% after just one injection. The method targets cancer cells with alpha radiation, sparing healthy tissue.
Researchers at RIKEN have demonstrated a method to prevent severe weather events by inducing small perturbations in the Lorenz 96 model. This approach utilizes the inherent chaos in weather systems to limit extreme events, which become more common due to climate change.
Scientists at RIKEN Center for Brain Science find that somatic mutations in six genes lead to intracranial aneurysms, which can be blocked with a drug. The study establishes the first non-surgical animal model of intracranial aneurysm and provides a potential new treatment option.
Scientists have successfully created a superlattice of lead sulfide semiconducting colloidal quantum dots that exhibits the electrical conducting properties of a metal. This breakthrough could lead to improved capabilities in devices such as solar cells, biological imaging, and quantum computing.
Researchers at RIKEN have created a composite material that can channel mechanical energy in one direction but not the other, allowing for efficient use of random vibrations. This property is essential for various biological functions and has potential applications in electronics, photonics, magnetism, and sound.
Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...
A large case-control study identified nine genes associated with stomach cancer risk and found that pathogenic genetic variations exacerbate the damage caused by H. pylori infection, significantly increasing the risk of gastric cancer. The study suggests that screening for pathogenic variants can help prioritize interventions.
Researchers at RIKEN Center for Integrative Medical Sciences discover genes and individual variations associated with atrial fibrillation, predicting stroke and mortality risk. They also uncover a potential treatment target, ERRg, involved in the pathogenesis of atrial fibrillation.
Inducing a hibernation-like state in mice using Q neuron activation has been shown to protect kidneys from oxygen deprivation and avoid harmful side effects. This technique could lead to new methods of performing heart surgery with reduced organ damage.
A new study published in Current Biology found that carrying crying infants for 5 minutes can promote sleep and reduce crying. The technique, known as the Transport Response, involves steady walking followed by sitting before laying the baby down to sleep. This method offers an immediate solution for parents of newborns struggling with...
Researchers created a rechargeable, remote-controlled cyborg cockroach with an ultrathin organic solar cell module powered by a lithium polymer battery. The device allows for wireless control of leg segments, enabling long-term operation without recharging.
Researchers at RIKEN have achieved error correction in a three-qubit silicon-based system, a major step toward large-scale quantum computing. This accomplishment demonstrates control of one of the largest qubit systems in silicon, providing a prototype for quantum error correction.
Researchers at RIKEN Center for Sustainable Resource Science found that adding ethanol to soil helps plants thrive during drought. The study showed that 75% of treated wheat and rice plants survived after rewatering compared to less than 5% of untreated plants.
Researchers at RIKEN have discovered how marsupials' hearts can regenerate for several weeks after birth, allowing for potential treatment of human heart disease. They found that inhibiting a protein called AMPK extended the period of regeneration in both mice and opossums, with minimal scarring.
A study published in Frontiers in Immunology found that Japanese herbal medicine DKT reduces colitis severity by preventing gut bacteria loss and increasing immune cells. It restores Lactobacillus levels and promotes type 3 innate lymphoid cells, alleviating inflammatory responses.
DNA recombinations of specific genomic sequences are found in both normal and diseased states, challenging the idea of a single genetic code. The study identified millions of mutations caused by recombination of repeated sequences Alu and L1, which may contribute to cancer and other genetic disorders.
A joint research group developed a robotic AI system that autonomously determines optimal conditions for growing replacement retina layers. The system achieved a 90% rate of differentiation efficiency in 185 days, compared to months of work by humans.
A new AI system uses artificial neural networks to recognize objects more accurately and stably, despite changing visual inputs. The system mimics human eye movements to improve machine vision capabilities, reducing errors in self-driving cars and other applications.
Researchers used high-resolution micro-CT scans to reveal key features in Palaeospondylus fossils, placing it as an early ancestor of tetrapods. The study resolves long-standing evolutionary mysteries, including the lack of teeth and dermal bones in the fossil record.
A theoretical study reveals that long-range quantum entanglement can persist at temperatures above absolute zero if a three-way interaction is present. This finding has significant implications for the development of room-temperature stable quantum devices, which could revolutionize future energy transport and computing.
Researchers used computer modeling to simulate the long-term evolution of a hypothesized type of supernova, known as D6. The study found that remnants of type Ia explosions are not necessarily symmetric, offering new insights into supernova physics. This finding has significant implications for using Ia supernovae as cosmic yardsticks.
Researchers have identified the Xist gene as a critical regulator of fetal development in mice, leading to miscarriage and abnormal placentas when epigenetic instructions are missing. The study's findings suggest that failed Xist imprinting can be 'cured' by targeting specific genes involved in histone modifications.
Researchers have identified a new type of programmed cell death, erebosis, that takes place in the intestines of fruit flies, contradicting the long-held theory of apoptosis. The process involves gradual cell death without nuclear membranes, mitochondria, and cytoskeletons, and is thought to play a role in gut metabolism.