Research from University of Eastern Finland finds SIP1 protein expression indicates advanced tumour stage, high recurrence risk, and poor prognosis. The study identifies SIP1 as a potential new prognostic factor for clinical use.
Patients with mild depressive symptoms post-surgery experience weaker functional capacity for up to five years. Enhanced psychosocial support may improve recovery in patients with this condition.
Researchers found that cautious fish are more vulnerable to fishing, while active exploratory behavior increases risk. Fish reared in enriched environments outperform those in traditional environments, showing improved survival rates in the wild.
The critically endangered Saimaa ringed seal has extremely low genetic diversity, which continues to decline due to its isolated population and limited migration. A recent study developed a method to identify individual seals using DNA samples from placentas collected from birth-lair sites.
A new technique using bioimpedance measurement reduces image degradation caused by respiratory motion during PET scans, enabling more accurate detection of cancers and heart conditions. This improved imaging quality can lead to better diagnosis reliability and treatment response monitoring.
A recent study at the University of Eastern Finland found that grandparents' help with childcare and emotional support influence mothers' decisions to have additional children. Additionally, parental grandparents' involvement is associated with fewer emotional and behavioral problems in grandchildren.
A recent study at the University of Eastern Finland developed a tool called Jeliot ConAn that uses conflictive animations to teach computer programming. The tool's intentional errors engage students in activities to find and signal errors, improving their critical thinking skills.
A recent Finnish study found that patients with cryptogenic strokes are more likely to have an enlarged left atrial appendage, suggesting a possible independent risk factor. The research suggests that this condition may be responsible for up to half of all cryptogenic strokes.
A new, easy-to-use EEG electrode set was developed to quickly attach on patients, reducing electromagnetic interference and allowing rapid diagnosis of severe brain function abnormalities. The set consists of 16 hydrogel-coated electrodes placed on hair-free areas, making it suitable for emergency care and field conditions.
Researchers from University of Eastern Finland propose a new method for measuring cardiorespiratory fitness by scaling maximal oxygen uptake and maximal workload by lean mass. This approach can avoid confounding effects of body adiposity, leading to more accurate assessments of an individual's functional capacity.
A Finnish study found that higher levels of physical activity during recess are associated with better reading skills, while participation in organized sports is linked to higher arithmetic test scores. Boys who spent more time engaging in activities like reading and writing on their leisure time also showed better reading skills.
Researchers developed new methods to reduce imaging time in myocardial perfusion imaging (MPI) by up to 50%, making scans easier for patients. The methods also correct errors caused by patient movement, resulting in error-free MPI images.
A study published in The Journal of Nutrition found that a blood sample can be used to assess dietary compliance. The researchers identified biomarkers in the blood that reflected consumption of key components of a healthy Nordic diet, including fatty fish, vegetables, and whole grains.
A recent study found that adolescents with aggressive behavior are more prone to drinking alcohol, while depression and anxiety do not increase the risk of alcohol use. The study also linked smoking, attention problems, early menarche, and parental divorce to increased alcohol consumption.
The study found that skull-base heating can result in hazardous temperature elevations when sonications are performed close to the skull-base. Three new methods to counteract this phenomenon were developed. Additionally, the formation of standing-waves is greatly reduced with specifically designed large-area ultrasound transducers.
A study found that overweight children with a common gene mutation are more likely to have elevated liver values. The research highlights the importance of healthy lifestyle habits from an early age, particularly for children carrying the risk gene.
A new diagnostic tool, combining data from multiple sources, can help clinicians diagnose Alzheimer's disease, frontotemporal dementia, and mild cognitive impairment with a Disease State Index. The tool also provides a visual representation of the findings in a Disease State Fingerprint.
The Physical Activity and Nutrition in Children Study found that low levels of physical activity combined with heavy use of electronic media increases the risk for type 2 diabetes and vascular diseases in 6-8 year-old children. Heavy electronic media use is also linked to higher risk factors even in physically active children.
New targets for drug therapy have been identified in the mast cell system, including enzymes and receptors. These targets include serine proteinases tryptase, chymase, cathepsin G, and proinflammatory cytokines.
A Finnish team of researchers identified a gene mutation in ameloblastoma, a tumour of the jaw. The discovery could lead to a targeted drug therapy reducing surgery and recurrence rates.
A recent study reveals that persons captured in medieval raids into present-day Finland, Russian Karelia, and the Baltic Countries were sold on remote trade routes extending to Central Asia. The demand for blonde girls and boys as exotic luxury items drove this trade, with only a few hundred of thousands reaching southern markets.
A recent study published in University of Eastern Finland found that the quality of dietary carbohydrates affects fatty acid composition in children's blood. High candy consumption and low high-fibre grain intake were linked to increased oleic acid levels, suggesting a potential role for delta-9-desaturase enzyme.
A study by University of Eastern Finland found that frequent alcohol consumption increases stroke mortality risk, particularly among middle-aged men. The study showed a threefold higher risk for those who consume alcohol more than twice a week compared to non-consumers.
A Finnish study found that brown trout exhibit predictable individual differences in behavioral traits such as activity levels and stress tolerance. The research, published in press, reveals that certain behaviors are heritable at a level of 14%, indicating a potential impact on fish populations and fisheries catches.
A midlife healthy diet was found to reduce dementia risk by almost 90% compared to the least healthy diet. Higher intake of saturated fats linked to poorer cognitive functions and increased risk of dementia.
A recent study at the University of Eastern Finland found that increasing fatty fish intake can increase large HDL particles in the blood, which protect against cardiovascular diseases. Regular consumption of fish, especially fatty fish like salmon and rainbow trout, may help improve lipid metabolism and reduce cholesterol levels.
Researchers at the University of Eastern Finland developed a novel treatment using RNA molecules to target and enhance vascular endothelial growth factor gene (VEGF-A) production. This approach significantly reduced myocardial infarction size in mouse models, offering new hope for heart disease treatments.
A new scientific blood analysis uses biomarkers and NMR spectroscopy to predict short-term mortality in the next five years. The study found that biomarker concentrations are crucial for normal metabolism, regardless of known risk factors.
The study analyzed the potential of energy wood resources in the Leningrad region of Russia, finding significant potential for intensification. Maximization of sustainable energy wood supply could create new jobs and business opportunities, but challenges like low productivity and technical accessibility need to be solved.
Researchers propose a new approach to understanding biology, shifting focus from genes to energy consumption and complex dissipative systems. The theory suggests that genes cannot determine biological activity, but rather, it is the energy flows within cells that drive emergence of properties.
A recent study published in Diabetologia found that metabolic risk factors cluster similarly in children and adults, increasing the risk of premature death caused by type 2 diabetes and cardiovascular diseases. Lifestyle interventions aiming at prevention should be invested in childhood to reduce the risk.
Researchers found that even modest weight reduction (5%) can significantly improve OSA and metabolism in overweight patients, preventing disease progression over four years. The study provides first-time long-term evidence of the effectiveness of weight loss in managing OSA.
A new study found that an early onset of dietary treatment may slow down the progression of Alzheimer's disease. The research, conducted on mice, suggests that even slight changes in diet composition can lead to significant changes in brain metabolism and improved memory performance.
A recent study published in Diabetes Care found that high concentrations of serum long-chain omega-3 fatty acids from fish consumption significantly lower the risk of developing type 2 diabetes. The research involved over 2,200 Finnish men, with those in the highest omega-3 group showing a 33% reduced risk.
A recent study published in Experimental Gerontology found that various forms of vitamin E, including tocopherols and tocotrienols, play a role in memory processes. The study revealed that higher total serum levels of vitamin E, particularly γ-tocopherol and β-tocotrienol, were associated with a reduced risk of cognitive impairment.
The Nordic SYSDIET study found that people with metabolic syndrome often have a diet high in salt and saturated fat, low in fibre and unsaturated fat. This can increase the risk of cardiovascular diseases and diabetes, emphasizing the importance of adherence to dietary recommendations for those at risk.
Women with prenatally diagnosed fear of childbirth are at a higher risk of postpartum depression, even those without a history of depression. The study analyzed data from over 500,000 mothers in Finland and found that nearly one-third of women experiencing postpartum depression had no previous history of depression.
Researchers at University of Eastern Finland developed a new method to remove uranium and other heavy metals from water using a solid material that collects metal ions directly from the solution. The CH Collector method is efficient, selective, and can recover even small amounts of metal without adjustments to the solution's pH.
Scientists at the University of Eastern Finland have created a new diagnostic tool for migraines, detecting 'hot spots' in pulsatile perfusion and asynchronous facial blood supply. The Blood Pulsation Imaging technique has significant implications for predicting, diagnosing, and monitoring migraine treatment.
Researchers developed new methods for synthesizing coumarin-based drugs, which showed promise as anti-inflammatory agents. The study revealed one of the pathways in which coumarins act, and understanding this pathway may help develop future treatments for chronic inflammation diseases.
A recent UEF study established reference values for heart rate variability in children, based on a sample of 465 kids aged 6-8. The findings indicate that short ECG recordings can be sufficient for reliable data collection, and show no significant differences between boys and girls.
Researchers at University of Eastern Finland have created new materials with potential biomedical applications, including gelation tendencies and structures in pure water. These supramolecular gels may serve as substitutes to restore or maintain bone tissue function, acting as scaffolds for cell adhesion and proliferation.
A nationwide study found that individuals with Alzheimer's are more prone to ischaemic heart diseases but undergo fewer related procedures. Despite this, reduced cognitive function was not a clear explanation for the disparity in treatment
A new study published in Medicine & Science in Sports & Exercise found that children with poor motor performance at the start of school tend to have poorer reading and arithmetic skills than their peers. The study suggests that motor performance and movement skills are more important for academic success during the first years of school.
A Finnish study found that binge drinking accelerates atherosclerosis and increases the risk of stroke in middle-aged men, particularly those who experience hangovers. The study also highlights the importance of moderate alcohol consumption and managing other risk factors such as hypertension and overweight.
A Finnish population-based study with over 4,000 participants found that eating five meals a day reduces the risk of obesity in adolescents. Skipping breakfast, on the other hand, is associated with greater BMI and waist circumference. Maternal weight gain during pregnancy also increases the risk of obesity in offspring.
The study identifies syndecan-1 as the human cell receptor used by baculovirus to enter cells, shedding light on the mechanisms of infection and facilitating gene therapy development. This breakthrough discovery increases our understanding of baculovirus interactions with human cells.
A healthy diet characterized by vegetables, fruits, berries, whole-grains, poultry, fish and low-fat cheese was associated with a lower prevalence of depressive symptoms. Increased intake of folate from sources like vegetables, fruits, and whole grains was also linked to a decreased risk of depression.
A recent study published in PLoS One reveals that impaired autophagy is linked to age-related macular degeneration, a leading cause of visual impairment. The researchers found that the lysosomal clean-up mechanism, or autophagy, plays a crucial role in clearing harmful protein accumulations behind the retina, which lead to vision loss.
A recent University of Eastern Finland study found that individuals whose expression of certain genes was not altered by vitamin D supplementation may already have a sufficient level of serum vitamin D or be disturbed in their vitamin D utilization. The researchers believe this approach can help identify potential beneficiaries of long...