A recent study published in Multiple Sclerosis and Related Disorders found that higher daily physical activity is associated with lower levels of fatigue in patients with relapsing-remitting multiple sclerosis. The study also suggests that maintaining functional capacity through suitable exercise can help reduce fatigue, improving the ...
Researchers at the University of Eastern Finland identified 58 plasma proteins associated with mental health risk in adolescents aged 11-16. These biomarkers could revolutionize early detection and prevention of mental health problems in young individuals.
A study of over 34,000 adolescents found that active school transport was associated with higher academic performance and lower school burnout. Leisure-time moderate-to-vigorous physical activity also showed significant benefits, particularly for mathematical skills and cognitive performance.
A new proposal suggests adopting an 'adolescent cholesterol passport' to prevent atherosclerosis, a leading cause of death worldwide. The tool would involve regular cholesterol screenings starting at age two, with the goal of detecting familial hypercholesterolemia and other genetic conditions early on.
A five-year study found that taking higher-than-recommended doses of vitamin D reduced the risk of atrial fibrillation by 27-32% in older men and women. The Finnish Vitamin D Trial involved 2,495 participants who received either a placebo or vitamin D supplementation, with lower risks observed in those taking higher doses.
A new study from the University of Eastern Finland explores how digital-based start-ups can leverage digital artifacts for early and rapid internationalisation. The research model provides a toolkit to identify opportunities for companies to adapt their digital services to international markets.
Finnish older golfers experience significant increases in physical activity levels, including moderate exercise and walking. Quality of life also remains high, with over 90% reporting good well-being during the pandemic.
A recent Finnish register-based study found no association between inhaled beta-2 agonist use and reduced risk of Parkinson's disease. Accumulation of alpha-synuclein protein is a key factor in the disease. The study controlled for age, sex, and comorbidities to rule out confounding factors.
Young adults with a history of heavy drinking since adolescence exhibit lower cortical gray matter thickness and altered neurotransmission, according to a recent study. Cortical thinning is associated with increased inhibitory neurotransmission, especially in the frontal and parietal lobes.
A recent study from the University of Eastern Finland reveals that most sustainability scholars support post-growth pathways for affluent countries, while less affluent countries favour either green growth or post-growth pathways. The study's findings challenge the prevailing green growth focused approach and emphasize the need for tar...
A study from the University of Eastern Finland found that pre-term and low birthweight infants have significantly fewer fractures in childhood compared to full-term and normal-weight newborns. The researchers suggest factors other than bone health may explain this difference, including reduced risk-taking behavior.
Researchers discovered a genetic variant protecting against Alzheimer's disease alters levels of proteins and peptides linked to amyloid-beta metabolism. The APP A673T variant demonstrates effectiveness in shifting APP processing from beta-amyloidogenic to non-amyloidogenic pathways, offering a new feasible strategy for AD prevention.
A large population-based randomized controlled trial found that providing better opportunities for exercise and group training can prevent falls and fall-related injuries among older women. The study showed a significant reduction in recurrent falls, fall-related injuries, and fractures caused by falls.
Researchers found that influencing adults' behavior is more effective than changing children's behavior. The PBIS approach helps create an operational culture that supports all children by clarifying behavioral expectations, providing training, and acknowledging success.
A pilot study at the University of Eastern Finland found that background music reduced dental students' stress levels and improved their performance during preclinical tooth preparation exercises. The music also increased motivation to learn and practice, while enhancing communication and quality of cavity preparation.
Researchers found that boreal wetlands are a substantial source of isoprene and terpenes, contributing to the formation of secondary organic aerosol and ozone. The emissions from these wetlands exhibit a strong exponential temperature response, making them a significant concern in a warming climate.
A long-term study at the University of Eastern Finland reveals a significant reduction in palsa area by over 75% from 1959 to 2021. Climate change has only a limited impact on active layer thickness, contradicting expectations.
Two recent studies conducted at the University of Eastern Finland found that renal hyperfiltration (RHF) is associated with an increased risk of mortality, independent of diabetes mellitus. A lower kidney filtration rate threshold may serve as a more precise measure for defining RHF.
A new study from the University of Eastern Finland identified 12 cell types involved in CAD pathogenesis. The genetic risk factors for CAD take effect via smooth vascular muscle cells, which change their phenotype as the disease progresses.
A new study found that sedentary time increases cardiac mass by 3.8g/m2.7, while moderate-to-vigorous physical activity results in a smaller increase of 1.2g/m2.7. Light physical activity shows no effect on cardiac mass but improves cardiac function.
A pilot study at the University of Eastern Finland found metabolites related to oxidative stress and transsulfuration to be associated with a history of sexual or physical abuse in depressed adolescent outpatients. The study's findings suggest that further research into the biological mechanisms underlying trauma is needed.
A recent study found that antidepressant fluoxetine facilitates the erasure of learned fear responses and enhances spatial learning in mice. The TrkB receptor in Parvalbumin interneurons is primarily responsible for this increased plasticity, suggesting a new target for treating psychiatric diseases.
A new study from the University of Eastern Finland shows that equine-facilitated therapy (EFT) can improve daily functioning and reduce perceived pain among patients with chronic low back pain. Statistically significant improvements were observed in domains such as sleep, reaching, and bending forward.
Adolescents with blood pressure above 130/85 mmHg are at risk of premature heart damage, which doubles in prevalence over a 7-year period. The study found significant differences in heart damage risks between males and females.
A study found that individuals with a history of atopic diseases, such as allergic asthma or rhinitis, had significantly lower rates of melanoma and skin cancer compared to non-atopic individuals. The risk of melanoma was up to 50% lower in atopic patients, and the overall risk of skin cancer was also reduced.
A new numerical model has been developed to predict cartilage degeneration after injury, revealing mechanisms of cell death and inflammation. The model suggests that mitigation of inflammation can lead to partial recovery of cartilage composition, opening avenues for potential therapeutic targets.
Research reveals that Mahogany trees shape the right-forewing of the Mahogany shoot borer, a forest insect-pest. The study found that the wing form differs between males and females, with larger wings on Cedro host plants.
A recent study found that dispersing marketing responsibility between personnel groups in early-stage operations promotes market orientation and improves profitability. Young firms should avoid rigid structures, instead focusing on information flow to support marketing in the early stages.
Researchers found that low-grade inflammation in adolescents can lead to higher blood pressure, insulin resistance, and increased risk of cardiovascular disease. The study also suggests that dietary factors, such as consumption of fruits, vegetables, and fibre-rich foods, can help prevent premature vascular damage.
A new study found that medication administration errors can lead to negative emotions in healthcare professionals, including feelings of fear, disturbed mood, sadness, and guilt. Immediate reassurance and guidance from seniors and colleagues can help mitigate these effects.
Researchers investigated micro-sized polyethylene's toxicity on human colorectal cancer cells, finding decreased cell viability and increased reactive oxygen species production. Exposure to high doses caused cell death and oxidative stress responses.
A new study has found that abnormality of intracortical inhibition in patients with progressive myoclonic epilepsy type 1 is associated with the magnitude of genetic change. The results suggest that transcranial magnetic stimulation could be useful in assessing patient prognosis and may have use as a marker of GABAergic impairment.
A study among 120 parents in Finland found that most felt competent in supporting their child's learning, but faced challenges in maintaining routines, relationships, and teacher support. Despite these difficulties, many reported increased freedom and autonomy, as well as improved parent-child interaction.
Regular use of vitamin D supplements was associated with a significantly reduced risk of melanoma and better skin cancer classification compared to non-users. However, the study did not find a significant association between vitamin D use and other skin changes or severity of photoaging.
A recent study from the University of Eastern Finland concludes that EU regulation does not adequately consider the environmental emissions of pharmaceuticals in global manufacturing supply chains. The researchers argue that the current GMPs and ERA regulation are limited in scope and weight, and do not prevent the release of pharmaceu...
A new study uses machine learning to predict poor glycemic control in patients with type 2 diabetes, identifying key factors such as prior glucose levels and anti-diabetic medicines. The findings suggest that data routinely collected for diabetes monitoring can reliably identify patients at risk of hyperglycemia.
A scoping review highlights the need for participatory methods in research addressing older people's learning. Older individuals are often included as subjects, but their roles vary, with some participating as informants or partners.
A study by the University of Eastern Finland and Vietnam National University found that people in urban areas have better access to healthcare than suburban residents. The researchers recommend digital healthcare solutions to improve healthcare quality and accessibility in a cost-effective manner.
A new chemical probe selectively inhibits human COQ8A in cells, targeting ubiquinone biosynthesis and providing a potential therapeutic strategy for diseases such as cancer. The inhibition of COQ8 has been linked to increased lifespan in certain organisms, suggesting its role in metabolic processes.
Recent studies from the University of Eastern Finland found that lower education levels and previous traumatic brain injuries may increase the risk of frontotemporal dementia (FTD). FTD patients were more likely to have cardiac disease and develop the condition earlier if they had a history of head injury.
A recent study from the University of Eastern Finland found that genetic background has an effect on the metabolism of essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid. The study showed that the FADS1 genotype modifies the responses to diets rich in alpha-linolenic acid and linoleic acid.
A Finnish study found that university students' experiences of remote learning differ significantly, with motivated students performing better and feeling less strain. The research highlights the importance of identifying individual differences in teaching to support student well-being.
A study of 1779 adolescents found that early-life elevated lipids and dyslipidemia are linked to worsening subclinical atherosclerosis. Conversely, treatment at age 17 effectively halted progression and even reversed it. This critical evidence emphasizes the need for early-life screening and prevention.
A recent study found that carnitine intake from breast milk promotes better growth and larger brain size at term equivalent age in very preterm infants. Carnitine levels were also associated with cerebellar size, suggesting a potential role in nervous system development.
Researchers have published seven draft genomes for Nordic hare species, including three heath hares with distinct grey/blue winter pelage. The findings suggest the heath hare colonized Scandinavia from the south after the last ice age, diverging from the mountain hare population.
The study reveals fundamental differences in cell regulation and energy metabolism between the mountain hare and brown hare, correlating with their distinct evolutionary histories. These findings provide insights into how genomic differences translate into adaptive phenotypic differences between species.
A study found atmospheric aerosol concentrations decreasing in Europe since 2000, but ground measurements and climate models show differing trends. The greatest differences were found in particle size, which affects cloud formation.
A new technique improves tumour targeting efficiency by fixing partial cell membrane coating on nanoparticles. The method increases immune escape and specific cancer targeting capability, enhancing therapeutic outcomes and reducing adverse effects.
A new study from Finland found that passenger car preheating produces significant particulate emissions equivalent to driving dozens of kilometers. The study measured auxiliary heater emissions and compared them to calculated emissions from driving, revealing the impact of preheating on air quality.
A one-year lifestyle intervention with a digital app and group counselling improved diet quality, reduced abdominal obesity and insulin resistance among 2907 Finnish adults at risk of type 2 diabetes. The study suggests that commitment to lifestyle counselling supports positive changes.