Researchers found lower serum TDP-43 levels in patients with C9orf72 repeat expansion or motoneuron disease, distinguishing them from other FTD subtypes. This study suggests TDP-43 as a potential biomarker for diagnosing specific FTD subtypes, enabling patient-specific interventions.
A study published in Hypertension Research suggests that weight gain from childhood with an optimal muscle-to-fat mass ratio may indicate excellent vascular health. The researchers found that increasing muscle mass was associated with optimal vascular function, especially in males.
Men with higher IQs in Finland are more likely to engage in skill-based gambling like horse racing and spend more money. The study suggests that these individuals enjoy the mathematical challenge posed by such betting, similar to solving crossword puzzles.
A study of 226 Alzheimer's family caregivers found that 61.5% experienced depressive symptoms at diagnosis, with 1 in 3 showing worsening symptoms over five years. The risk was not linked to disease severity or individual backgrounds.
A Finnish study of 1,064 teachers found that those with persistent turnover intentions are more likely to experience burnout, cynicism, and poor work environment fit. Positive experiences and autonomy in the workplace can mitigate these risks.
A new study shows that precipitation events decrease atmospheric aerosol concentrations, particularly sulphate, in boreal forest environments. The researchers found significant formation of sulphate mass in non-precipitating clouds, which can improve the accuracy of climate models estimating aerosol transport.
A new study reveals that young people, refugees, and older adults with limited resources perceive their health and wellbeing capabilities as weak. The capability framework shows a strong impact of individual factors and structural factors on perceived wellbeing.
A new study reveals that conifers release substantial quantities of volatile organic compounds in response to bark-feeding weevils, providing cues to neighboring seedlings. This complex communication process is altered by air pollution.
Researchers found that lettuce takes up nanoplastics from soil and transfers them into the food chain, with particles detected in insects and fish. The study highlights potential health risks to herbivores and humans due to tiny plastic particles in soil.
Research suggests that arterial stiffness increases blood pressure in adolescents due to insulin resistance, not body fat. Healthy lifestyle choices like exercise and a balanced diet may help lower blood pressure in this age group.
A study by University of Eastern Finland explores the role of self-disclosure in forging long-term B2B customer relationships. Sales professionals disclose personal and company information, leading to deeper relationships with increased trust, communication, and shared goals.
A new study from the University of Eastern Finland reveals that gamer rage in children is often caused by their own performance, social factors, and daily life stressors. Children frequently compare their in-game performance to others, leading to frustration when they lose or perform poorly.
A large meta-analysis suggests that vitamin D supplementation may alleviate depressive symptoms in adults with depression. The analysis included 41 studies and found that vitamin D was more effective than a placebo in alleviating symptoms. However, the results were limited by study heterogeneity and risk of bias.
Arterial stiffness in adolescence is a novel risk factor for hypertension, insulin resistance, and type 2 diabetes in young adulthood and mid-adulthood. Risk factors include maternal smoking habits, early life smoking patterns, high salt intake, genetic inheritance, obesity, and elevated blood pressure from childhood.
A comprehensive protocol for analysing nanomaterials has been introduced to support their safe use in various industries. The protocol allows researchers to determine and quantify metal-bearing nanomaterials in biological tissues and cells at trace-level concentrations.
A new study at the University of Eastern Finland shows that digital entrepreneurship requires building diverse networks, transparency, and courage to adapt. The research developed a digitalisation-driven networking model based on network and effectuation theory, offering insights for inexperienced digital entrepreneurs.
A study found that individual factors such as education level and health status are more influential on leisure-time physical activity than municipal resources. Commuting physical activity is also lower in rural municipalities due to longer distances and limited public transport.
Research reveals that elephant migration routes in Namibia are experiencing declining vegetation due to human activities. The study, published in Sensor journal, used remote sensing data to assess the impact of wildlife on vegetation cover change.
A new study found that pregnant women's use of alcohol correlates with that of their partner, highlighting the importance of both parents reducing their alcohol consumption. The research, which analyzed data from 14,822 Finnish women and their partners, showed that exposure to alcohol can have detrimental effects on fetal development.
A new study from University of Eastern Finland indicates that telemedicine played a crucial role in maintaining essential type 2 diabetes care amid the COVID-19 pandemic. Despite reduced face-to-face appointments, remote services for diabetes management cushioned the decline and kept overall contacts only 9% lower than 2019.
A new study from the University of Eastern Finland found that nearly 30% of older home care clients experienced eating problems, including poor appetite, chewing, and swallowing issues. The study highlights the importance of maintaining good oral health to prevent these problems.
A recent study by University of Eastern Finland explores how care ethics in social entrepreneurship benefits society as equally as profit margins. Practising care ethics in businesses enhances local communities' self-esteem and economic activity, while also addressing social structures that maintain poverty and exclusion.
A new study from Finland found that adolescent athletes' motivation for school and sports are strongly related, with female students generally showing higher motivation for both. Male students tend to be less interested in school, but not in sports, suggesting a need for targeted support to develop their academic motivation.
New study finds tree branches move downward up to 20 cm at night as leaves and branches replenish water storage. This phenomenon has practical applications, including monitoring plant water status in greenhouses to automate watering regimes.
A new study from the University of Eastern Finland found that climate change is causing the pine beauty moth to shift its range northward 50 years ahead of earlier predictions. The larvae feed on pine needles, and their population size is linked to warmer temperatures and forest health decline.
A new study from the University of Eastern Finland reveals that student satisfaction in flipped classrooms is built on systematic guidance, comprehensive understanding of the subject matter, and a safe learning atmosphere. Teachers must also consider students' technological skills and their own contact teaching abilities.
A new study published in Scientific Reports reveals that regular high-intensity interval training exercise can significantly decrease fasting glucose levels and waist circumference, while improving oxygen consumption rates in patients with non-alcoholic fatty liver disease. Exercise also modifies amino acid metabolism in adipose tissue...
A new study from the University of Eastern Finland found that frontotemporal dementia patients with extrapyramidal symptoms have significant brainstem atrophy and reduced metabolism, facilitating differential diagnostics for FTD. This can help distinguish between FTD and other diseases causing extrapyramidal symptoms.
Researchers at the University of Eastern Finland have developed a novel nuclear microRNA, miR-466c, that regulates vascular endothelial growth factor A (VEGFA) expression in response to hypoxia. The drug has commercial relevance for treating ischemic cardiovascular disease by increasing VEGFA levels.
A self-standing mesoporous Si film anode has been developed for lithium-ion batteries, exhibiting excellent performance without the need for additives or binders. The film's pore characteristics show a strong correlation with electrode performance.
A new study from the University of Eastern Finland shows that liquid biopsy can detect cancer mutations months before recurrent breast cancer is detected. This method uses biomarkers released by cancer cells in serum samples to assess changes in intratumoural heterogeneity and provide a more accurate clinical picture.
Researchers discovered a micro-protein, Nrs1, that supports cell division and proliferation when nutrients are scarce in yeast cells. This finding sheds light on how evolution subtly reshapes genome plasticity to adapt to changing environments.
Researchers at the University of Eastern Finland used molecular modeling to investigate nano-plastic transport into cell membranes. The study found that some microplastics can passively penetrate the membrane, potentially causing adverse health effects.
Researchers developed a new cell model of the olfactory mucosa, which is impaired in patients with Alzheimer's disease. The study provides new insights into the disease pathophysiology, including the potential role of viral infections and air pollutants in brain function.
A new study reveals that Viking raids in ancient Scandinavia had a profound effect on the economic and political landscape of modern-day Russia. The plunder economy, which existed until the early Middle Ages, continued to shape local economies and societies in Eastern Russia, particularly in the Volga, Caspian, and Caucasus regions.
Research reveals three modes of thought among Finnish forest owners: one views biodiversity loss as an emergency and advocates for radical change, while others see no problem. The study highlights the importance of acknowledging biodiversity loss denial in forestry discussions.
A comprehensive study investigates the metabolism of four drugs in rabbit eyes, revealing different enzyme profiles from liver metabolism. The findings provide valuable information for advancing ophthalmic drug development.
Researchers identified water molecules' impact on protein dynamics and drug target residence time, suggesting that a long target residence time can be important for drug efficacy. This understanding enables more rational drug design in the early stages of drug discovery projects.
Regular physical activity significantly changes metabolite profiles, associated with a lower risk of type 2 diabetes. The study found improved insulin secretion and reduced fasting glucose levels in physically active men.
A new study found that disease-modifying antirheumatic drugs do not protect people with rheumatoid arthritis from developing Parkinson's disease. However, using chloroquine or hydroxychloroquine was associated with a lower risk of PD. The study controlled for various factors, including comorbidities and age.
Researchers found that adolescent arterial stiffness may be a causal risk factor for hyperinsulinaemia and insulin resistance in young adulthood. Arterial stiffness also temporally precedes low HDL-cholesterol in young adults, with a positive association with triglyceride levels.
A large-scale Finnish trial found that taking high doses of vitamin D (1600-3200 IU/day) for five years did not decrease the incidence of cardiovascular disease or cancer. The study's findings support the recommendation of 10 micrograms (400 IU) per day for adult Finns, but do not suggest using large doses as a preventive measure.
Researchers found that EEG arousal intensity varies by respiratory event type and severity in OSA, affecting sleep disruption. The study reveals distinct patterns of gamma power during arousals from different types of respiratory events, such as obstructive apnoeas and hypopnoeas with varying degrees of blood oxygen desaturation.
Researchers at the University of Eastern Finland have developed simpler measurement technologies for diagnosing sleep disorders, enabling more accurate analyses. The new methods use reusable sensors in home environments, reducing costs and increasing patient comfort.
A study in young psychiatric outpatients with episodic or chronic depression found differences in one-carbon and energy metabolism, which could aid in diagnosis and targeted treatments. The preliminary results suggest potential mechanisms behind chronicity, highlighting the need for larger cohorts to confirm findings.
A previously unknown source of the potent greenhouse gas nitrous oxide has been found in East Siberian Yedoma permafrost. The discovery highlights the significance of thawing permafrost as a globally important positive feedback to climate change.
A new study from the University of Eastern Finland found that patients with type 2 diabetes often do not receive adequate cholesterol-lowering treatment, despite guidelines recommending statin prescriptions for elevated LDL-C levels. Women tend to have higher average LDL-C levels and receive less statin treatment than men.
A recent study published in Hypertension suggests that adolescent arterial stiffness may increase the risk of systolic and diastolic hypertension by 20% and 2-fold, respectively, seven years later. Higher arterial stiffness levels were also associated with an increased risk of abdominal and whole-body obesity.
A new study from the University of Eastern Finland reveals that Finnish parents regard assessment as primarily a tool for supporting pupils' learning and growth. They hope for diverse forms of assessment, including numerical evaluations, to motivate children and facilitate comparison. The researchers propose that schools engage in clos...
Changes in Finnish aapa mires, characterized by wet fens and peat mosses, can be detected from Landsat satellite data. The study found a significant increase in Sphagnum mosses over the past few decades, accelerated by land use and climate change.