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University of Southern California


Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

Researchers have discovered 15 genomic loci that either accelerate or decelerate brain aging, offering potential new drug targets to combat Alzheimer's disease and other degenerative brain disorders. The study, led by USC researchers, found overlap with genes involved in depression, schizophrenia, and cognitive functioning.

SourceUniversity of Southern California·JournalNature Neuroscience·TypeData/statistical analysis·DateApr 5, 2022

Hate speech on social media is fueled by users’ shared moral concerns, USC study shows

A USC study found that people whose moral beliefs align closely with their online community are more prone to radicalization, posting hate-speech messages. The research also replicated findings in another extremist network on Reddit, highlighting the role of morality in fueling online radicalization.

SourceUniversity of Southern California·JournalSocial Psychological and Personality Science·TypeExperimental study·DateDec 16, 2021

Now scientists can efficiently screen billions of chemical compounds to find effective new drug therapies

Researchers at USC Dornsife College of Letters, Arts and Sciences have created a process that increases the chances of finding effective drugs in a fraction of the time and at significantly less expense than current methods. V-SYNTHES, a virtual method developed by Vsevolod Katritch and colleagues, uses synthons to efficiently puzzle t...

SourceUniversity of Southern California·JournalNature·TypeComputational simulation/modeling·DateDec 15, 2021

New mathematical model to predict viruses

A new mathematical model developed by USC researchers uses a generator-based approach to analyze mutations in genomic datasets, allowing for the prediction of virus evolution and detection. This tool can be applied to various pathogens, including crops, enabling proactive protection measures.

SourceUniversity of Southern California·JournalScientific Reports·TypeObservational study·DateDec 9, 2021

Two beams are better than one

Researchers have made a breakthrough in Free Space Optical Communication (FSOC) by sending two laser beams together, reducing distortion caused by atmospheric turbulence. This innovation promises to improve wireless communication speeds and security for applications such as high-speed internet, airplanes, drones, and satellites.

SourceUniversity of Southern California·JournalNature Photonics·TypeExperimental study·DateOct 20, 2021

What does it take to be a marine?

A study analyzing data from 3,438 trainees has identified key factors associated with success in Recon Marine training, including prior life experience, athletic experience, and physical performance metrics. The research aims to inform military recruitment and training strategies, advancing novel ways to recruit and retain for the U.S....

Aided by stem cells, a lizard regenerates a perfect tail for first time in more than 250 million years

A USC-led study has improved lizard tail regeneration through stem cell-based therapy, leading to the creation of tails with skeletal and nerve tissue on both sides for the first time in history. This breakthrough informs efforts to improve wound healing in humans, particularly for injuries that don't naturally regenerate.

SourceUniversity of Southern California·JournalNature Communications·TypeExperimental study·DateOct 14, 2021

USC researchers find that interrupting a high-fat, high-calorie diet with regular cycles of a fasting-mimicking diet helps mice live a longer, healthier life

Researchers found that regular cycles of a fasting-mimicking diet in mice helped counteract the negative effects of a high-fat, high-calorie diet. The study suggests that this diet may have potential as 'medicine' to prevent obesity and heart disease.

SourceUniversity of Southern California·JournalNature Metabolism·TypeExperimental study·DateOct 14, 2021

A computer algorithm called ‘Eva’ may have saved lives in Greece

A new study suggests that Greece's computer algorithm 'Eva' caught nearly twice as many asymptomatic infected travelers as traditional testing methods, helping to curb COVID-19's spread. The AI-powered system used real-time data to identify high-risk visitors for targeted testing, revealing its potential in managing the pandemic.

SourceUniversity of Southern California·JournalNature·TypeComputational simulation/modeling·DateSep 22, 2021

A T-cell power-up for tumor treatments

Researchers at USC Viterbi School of Engineering have discovered a way to boost the effectiveness of CAR T-cell therapy for treating solid tumors, including breast and melanoma. By engineering CAR T-cells to produce an enzyme called adenosine deaminase, they break down an immune-suppressive microenvironment, allowing cancer-killing cel...

SourceUniversity of Southern California·JournalHuman Gene Therapy·TypeExperimental study·DateSep 8, 2021

A group’s moral values may help determine the likelihood of hate-motivated harmful acts

A study published in Nature Communications suggests that a county's moral values, particularly binding values, can predict the prevalence of hate groups and extreme behavioral expressions of prejudice. The research used geospatial modeling and psychological experimentation to analyze data from over 3,100 US counties.

SourceUniversity of Southern California·JournalNature Communications·TypeData/statistical analysis·DateJul 28, 2021

How does the world use emojis?

A new study by USC researchers found that emojis represent universal human emotions across countries and continents, while also reflecting cultural differences. The most widely used emojis, such as the heart, were predominantly used in the English-speaking world, Spanish-speaking nations, and Arabic speakers.

SourceUniversity of Southern California·JournalOnline Social Networks and Media·DateJul 14, 2021

Latest tests on 6G return surprising results

A recent study published in Proceedings of the IEEE reveals that high-frequency signals can be managed more effectively than previously thought, addressing key challenges in 6G technology. The research has significant implications for applications such as haptic internet, mobile edge computing, and holographic communication.

SourceUniversity of Southern California·JournalProceedings of the IEEE·DateJun 10, 2021