Researchers at Yale University discovered a rare childhood disorder that mimics inflammatory bowel disease, revealing the underlying genetic cause of chronic inflammation. The study identified ELF4 as a crucial regulator of inflammation, suggesting its role in multiple diseases.
A new study by Yale social psychologist Cydney Dupree found that Black and Latinx conservatives use language associated with competence more frequently than their liberal counterparts in mostly white settings. This phenomenon, dubbed 'competence upshift,' helps them distance themselves from negative racial stereotypes.
A Yale study finds that pandemic-induced paranoia was particularly acute in states with low mask mandate adherence and increased acceptance of conspiracy theories. Increased feelings of paranoia were associated with erratic choice behavior and a higher likelihood of endorsing conspiracy theories.
A new study by Yale School of the Environment Associate Professor Narasimha Rao found that poorer households in India are disproportionately affected by air pollution caused by other sources. The study highlights that wealthier households contribute less to pollution but reap fewer benefits from cleaner alternatives.
A Yale study found that US methadone clinics were slower to accept new patients and longer in providing treatment compared to Canadian clinics during the pandemic. Clinics with open access models provided timelier treatment access, but only a fraction of US clinics offered this option.
A Yale study suggests that newborn mammals can anticipate and respond to visual stimuli even before birth. The research reveals that waves of activity emanate from the neonatal retina in mice before their eyes open, mimicking the movement patterns they'll encounter after birth.
Researchers discovered how flies choose their food based on neural activity and hunger levels, with findings that may apply to human food choices too. Hungry fruit flies prefer sweet, nutritious food over lower-calorie options when hungry, but adapt their preferences when presented with novel foods.
A recent study by Yale researchers found that psilocybin increases the density of dendritic spines, aiding information transmission between neurons and potentially treating depression. Mice subjected to stress showed behavioral improvements after receiving psilocybin, suggesting a possible therapeutic effect.
A Yale University study found that direct deposit of wages into female-owned bank accounts increased labor force participation and earnings among Indian women. The intervention also liberalized their personal beliefs about working women, reducing social stigma associated with working outside the home.
A study by Yale researchers found that the common cold virus can trigger an immune response that halts replication of the SARS-CoV-2 virus. Exposure to rhinovirus was shown to protect against COVID-19 infection, with the immune system responding rapidly to the threat.
A new study identifies a separate species of tree hyrax, Dendrohyrax interfluvialis, which inhabits the wet and dry forests between the Volta and Niger rivers in West Africa. The species is characterized by distinct barks, anatomical differences, and genetic distinctness from other hyrax lineages.
A massive die-off of sharks occurred 19 million years ago, with more than 70% of the world's sharks dying off - a phenomenon not seen since the Cretaceous-Paleogene mass extinction event 66 million years ago.
A new Yale study finds that seabed burrowers were helpful in creating conditions for complex animal life to expand. Bioturbation altered the chemical makeup of the sea and oxygen levels, fostering the emergence of increasingly productive ecosystems during the Cambrian explosion.
A new study from Yale University found that a ban on flavored vaping products in San Francisco's school district led to a doubling of conventional cigarette smoking among high school students. The study suggests that flavor bans may inadvertently push youth toward cigarettes, highlighting the need for caution and alternative policies.
A new study has identified 178 gene variants linked to major depression, providing insights into the disorder's genetic complexity and potential treatments. The findings may help identify individuals most at risk of depression and inform personalized treatment approaches.
A new brain imaging study reveals that infants use the hippocampus to recognize patterns, despite limited episodic memory, with the brain region doubling in size between 2-4 years old
A new study finds that adding a small molecule can rip away the cloak shielding HIV-infected immune system cells, making them susceptible to patient's own antibodies. Researchers hope this breakthrough may one day eliminate the need for long-term antiretroviral treatments.
Researchers at Yale University found that autoantibodies in severe COVID-19 cases can attack healthy tissue and organs, leading to increased disease severity. The study also suggests that long-lived rogue antibodies may contribute to lasting medical symptoms, or long COVID cases.
A Yale-led study discovered that children with multi-system inflammatory response (MIS-C) exhibit unique immune system signatures, including elevated alarmins and adaptive immune responses. These findings may aid in diagnosis and early treatment of the condition, which can be fatal if left untreated.
A new study from Yale University reveals that the shape of a dinosaur's inner ear can provide reliable signs about its behavior, including flying ability, movement, and parenting. The research found clusters of species with similar inner ear traits corresponding to their behaviors.
A new study reveals that skin's epidermis layer is comprised of an army of immune cells that station themselves at regular intervals across the skin. When necessary, these cells reposition themselves to protect vulnerable areas, forming a dynamic surveillance system.
A Yale scientist, Douglas Booher, named an ant after R.E.M.'s Michael Stipe's friend Jeremy Ayers, a Warhol 'Superstar'. The ant was discovered in Ecuador and had unique features that set it apart from other species. Booher confirmed the discovery with German entomologist Phillip Hoenle and was joined by Stipe to name the new species.
A Yale-led study reveals that early humans were ecosystem engineers, using fire to prevent forest regrowth and create open woodlands. This finding suggests that humans were learning to use fire in novel ways by the Late Pleistocene period.
A Yale-led study found that new medicines and vaccines approved for use in the US are often not accessible in countries where they were developed, highlighting gaps in access to new medications. The study suggests that governments of host countries should require pharmaceutical companies to commit to submitting marketing approval appli...
A Yale University study found that genetic factors control developmental abnormalities, including pregnancy loss and autism. Researchers examined placental data from nearly 50 sets of twins and discovered similar frequencies of abnormal cell growths in identical twins, suggesting genetics play a key role.
A new digital decision-aiding tool, ASSIST, has been developed to help physicians choose between non-invasive diagnostic tests for patients with chest pain. The tool uses machine learning techniques to identify the most appropriate imaging test based on patient characteristics.
A Yale University study found that pregnant women infected with COVID-19 are more likely to experience preterm births and neonatal problems due to a robust immune response in the placenta. The researchers also discovered that the virus's ACE2 receptors are present in most placentas during the first trimester, but disappear later.
A Yale University study reveals that conversion among swing voters was the primary factor behind Donald Trump's electoral success in 2016. The researchers found that voters switching from Democrat to Republican more consistently explained the GOP's gains than did increases in voter turnout.
A new study by Yale researchers found that girls with autism tend to develop the condition in a different region of the brain than boys, with a larger number of genetic mutations. The findings suggest that girls may have a natural protective effect against developing autism.
A recent study found that 43.3% of veterans reported positive psychological benefits during the pandemic, including greater appreciation for life and closer interpersonal relationships. Psychological interventions promoting post-traumatic growth may help prevent suicide among veterans.
Researchers at Johns Hopkins and Yale found that free online courses teaching principles of positive psychology can enrich lives, reporting greater mental health benefits than a comparable course without exercises.
A recent study by Yale Cancer Center reveals that young patients with early-onset colorectal cancer (under age 50) have a better survival rate than those diagnosed at older ages. After adjusting for stage at diagnosis, these patients had a 5% lower risk of death compared to those diagnosed between 51-55 years old.
Researchers at Yale Cancer Center discovered that acquired resistance to immune checkpoint inhibitors is linked to reduced MHC-II molecule expression and increased tumor hypoxia. Combining immune checkpoint inhibitors with anti-hypoxia agents can slow the development of resistance.
Researchers at Yale Cancer Center have advanced a tumor-targeting and cell penetrating antibody that can deliver payloads to stimulate an immune response against melanoma. The study achieved almost complete tumor suppression in mice with melanoma tumors following intravenous injection of antibody/RNA complexes.
A Yale study analyzing 40 million deaths found that even short-term exposure to ambient CO below current guidelines was associated with increased mortality. The research suggests reducing ambient CO concentrations could achieve considerable public health benefits through stricter control of traffic emissions.
A recent national study found that 43.3% of veterans reported positive psychological benefits, including greater appreciation for life and closer relationships, during the pandemic. This is more than five times the number of those who had contemplated suicide.
A collaborative team identified multiple genes with recurrent alterations in uLMS, including HRD, ALT, C-MYC/BET, and PI3K-AKT-mTOR pathway, as potential targets for new treatments.
Researchers found that high biodiversity in aquatic ecosystems is essential for meeting human needs for micronutrients like calcium and iron. Seafood from biodiverse sources can help combat 'hidden hunger,' a phenomenon where people have access to enough calories but not enough nutrients.
Researchers found that monkeys exhibit same patterns as humans in learning from consciously experienced and subliminally presented visual cues. This suggests that monkeys possess two levels of processing, one of which is conscious.
Researchers at Yale have created a global map of undiscovered species, revealing that Brazil, Indonesia, Madagascar, and Colombia hold the greatest opportunities for new discoveries. The study also highlights the importance of taxonomists in finding undiscovered species, and emphasizes the need for more funding to close knowledge gaps.
Research using fMRI scans reveals that babies under a year old use areas of their frontal cortex to focus attention, previously thought to be immature. This discovery sheds light on the neural origins of attention in infants, potentially informing early childhood education and neurodevelopmental disorder research.
Researchers at Yale University have developed a method to recreate the earliest stages of cellular development, allowing scientists to track individual cell lineages. By analyzing tiny variations in skin cells' genomes, they can reconstruct the early lineage trees for each person, shedding light on human biology and potentially diagnos...
The gut's immune system plays a critical role in regulating nutrient absorption and warding off toxic chemicals and life-threatening bacteria. Researchers found that gamma delta T cells suppress interleukin-22 expression, allowing for the activation of digestive enzymes and nutrient transporters.
A new study suggests that lightning strikes provided sparks of life for early Earth, unlocking phosphorus to create biomolecules. The researchers estimated that 0.1 to 1 quintillion lightning strikes occurred over a billion years, providing usable phosphorus.
A new study led by Yale University suggests that home testing for SARS-CoV-2 could significantly reduce total infections and mortality at a reasonable cost. By providing households with rapid antigen tests to identify potential contagion, individuals can self-isolate before spreading the disease.
Researchers at Yale University have developed a model where human red blood cells are rescued in circulation using combined liver and growth factor humanization. This breakthrough has the potential to treat diseases such as myelodysplastic syndrome, sickle cell disease, and malaria.
A new trial shows that immunotherapy drug teplizumab can delay the onset of Type 1 diabetes in people at high risk by an average of five years compared to a placebo. The study, published in Science Translational Medicine, found reduced T-cell damage and improved insulin-producing beta cells in those who received the treatment.
Researchers have identified 40 genes that suppress axon regeneration in central nervous system cells, hindering recovery from brain and spinal cord injuries. By editing out one gene, they restored axons in mouse models with glaucoma, suggesting a potential new approach to treating neural damage.
Researchers discovered five proteins associated with neutrophil activation that can predict severe COVID-19 outcomes. These biomarkers are elevated in patients who later require ICU admission or die from the virus.
A Yale-led study found that at least 4% of registered voters in Wisconsin were incorrectly identified as having changed addresses, potentially disenfranchising them. Minority voters were twice as likely to cast ballots using their original address after being flagged as movers.