Research on lowering risk across health and infrastructure. Covers grid-disturbance detection, crowd-safety modeling, AI energy projects, and statin eligibility.
Researchers tested zoledronic acid's effects on cellular senescence using multiple approaches. The study found that zoledronic acid killed senescent cells with minimal effects on non-senescent cells and reduced circulating SASP factors, including CCL7, IL-1β, TNFRSF1A, and TGFβ1.
Menopausal hormone therapy is recommended as a first-line treatment for women without risk factors, offering relief from hot flashes and other symptoms. Non-hormonal therapies can also help alleviate symptoms in those with risk factors or preferring alternative options.
A new study found that being overweight or obese during early and middle adulthood increases the risk of gastrointestinal cancers in later life. The research also suggests that frequent aspirin use does not modify this increased risk.
Researchers identified two crucial drivers of brand extension success: parent brand equity and extension fit. The study suggests five groups of moderators to improve brand extension strategies.
A Bangor University paper quantifies the carbon benefits of ending bottom trawling, finding only a small fraction of seabed carbon reacts to disturbance. The study challenges the validity of previous claims and suggests using 'carbon credits' for banning trawling may actually increase overall CO2 emissions.
A retrospective cohort study of U.S. veterans found that adding a GLP1 receptor agonist to diabetes treatment reduced the risk of major adverse cardiovascular events and heart failure hospitalization by about 20% compared to DPP4 inhibitors. The study's findings will aid clinicians in choosing a diabetes drug regimen for older patients.
A study of 390,000 infants found that those born to mothers with opioid use disorder or neonatal opioid withdrawal syndrome had a higher risk of postneonatal infant mortality. The study highlights the need for supportive interventions during and after pregnancy to reduce adverse outcomes.
A new study by University of Waterloo researchers found that Canadian electronic waste (e-waste) has more than tripled in the last two decades, generating close to a million tons in 2020. E-waste generation per person has increased from 8.3 kg to 25.3 kg between 2000 and 2020.
A University of Gothenburg study shows that increased physical activity, with four hours of weekly exercise, doubles the chances of recovering well by six months after a stroke. Men and people with normal cognition tend to maintain an active lifestyle more often, leading to better recovery outcomes.
A new interactive online Fragility Fracture Decision Aid can help clinicians and patients visualize their individual risk of fracture. The Canadian Task Force on Preventive Health Care recommends a "risk assessment–first" screening process for women 65 years and older, centered around shared decision-making with primary care providers.
A recent Fred Hutchinson Cancer Center study found that fibroids were associated with an increased risk of ovarian cancer in both Black and white women, while hysterectomy modified this risk for white women but not Black women. The study highlights the need for further research into racial disparities in ovarian cancer risk.
Researchers analyzed data from over 20,000 US adults, finding that those who lost at least 5% of their body weight showed higher diet quality and more moderate physical activity. However, the study also found that many individuals relied on unsustainable non-evidence-based approaches for weight loss, highlighting the need for a paradig...
Researchers discuss the importance of biomarkers in breast lump management, enabling patients to make informed decisions between proactive treatment and watchful waiting. The development of biomarkers could provide personalized risk assessments and guide treatment strategies for women with breast lumps.
Strokes can be largely prevented through education and lifestyle changes, such as moving more, healthy eating, and managing blood pressure. The American Stroke Association is launching a digital tool to educate people on stroke warning signs and risk factors, particularly for diverse populations.
Researchers found that disordered thrift shop displays can enhance perceptions of hidden treasure, but risk perceptions outweigh this effect, leading to a net negative impact on purchase likelihood. High inventory knowledge by sellers mitigates these risks, increasing perceptions of curated products and consumer trust.
Researchers at Columbia University found that increased access to mental health care is associated with lower suicide rates in the US. The study used a new method to measure access to care and found that areas with shorter travel times to providers had significantly lower suicide rates.
Central bank balance sheet policies are effective if investors behave according to a plausible alternative behavioral assumption to rational expectations. Professors Iovino and Sergeyev's new paper finds that level-k thinking breaks away with the demanding assumption of rational expectations, allowing agents to have varying degrees of ...
Researchers developed a novel biomarker-based indicator of the Mediterranean diet, which incorporates levels of fatty acids and carotenoids in blood. The study found that those with higher scores had lower risk of developing type 2 diabetes, suggesting a stronger link than self-reported diet adherence.
A study found that residents of economically disadvantaged areas were more likely to use violence against others after experiencing injuries. The research suggests that targeted interventions may be necessary to address neighborhood-level issues contributing to violence.
A new meta-analysis found that clozapine is associated with decreased insomnia and a lower risk of suicide in patients with schizophrenia. The study suggests that clozapine's ability to improve sleep quality may be linked to its reduced suicide risk, and highlights the importance of assessing and treating insomnia in these patients.
A team from Kennesaw State University is studying the cultural, historical, and health significance of artisanal alcohol production in Cabo Verde. The researchers aim to understand the economic, social, and environmental impacts of grogue production, a national liquor produced by fermenting sugar cane.
A new study finds that buprenorphine initiation rates and six-month retention rates remain flat despite policy changes aimed at increasing access to the medication. Only 22% of patients who started treatment kept refilling their prescriptions for at least six months, highlighting barriers to prescribing enough of the life-saving drug.
A study by Oregon State University found that a metal bar installed on the crab-sorting table can reduce the strain on fishermen's bodies and prevent injuries. The researchers tested different banger bar configurations and found that higher bars and triangular bars were the most effective in reducing muscle activity and joint moment.
A new study finds that an estimated 6.5 million Californians are concerned about a friend or family member who may harm themselves or others due to substance misuse, history of violence, or firearm access. The survey shows that 85% of respondents who knew someone at risk took actions to reduce the risk, but few addressed firearm access.
A new study comparing outcomes between Ontario and New York State found patients in Ontario more likely to die within a month of procedure due to inadequate availability and long wait times. The study suggests that improved access to TAVR may lead to better post-procedural outcomes.
A study of 167,000 non-hospitalized patients revealed that neutralizing monoclonal antibody treatment for COVID-19 was associated with significant reductions in emergency department visits, hospitalization rates, and mortality. These findings suggest targeted risk stratification strategies may optimize future nMAb treatment decisions.
A global study published in Cochrane Reviews found that consuming cranberry products reduces the risk of repeat symptomatic UTIs in women by more than a quarter. The review also showed benefits for children and people susceptible to UTIs following medical interventions, with minimal side effects reported.
A new report by the USGS and FEMA estimates that earthquakes cost the nation an average of $14.7 billion annually in building damage and associated losses. The report's updated estimate is twice the previous annual figure due to increased building value and improved hazards analysis.
A new online tool, CogDrisk, has been found to be effective in assessing dementia risk, providing a personalized report for patients and GPs. The tool uses a combination of statistical methods and modifiable risk factors to predict dementia risk, including physical activity, obesity, high blood pressure, smoking, and poor diet.
Researchers found that removing ovaries during a benign hysterectomy increases the risk of hospitalization for cardiovascular disease in premenopausal women, but not necessarily for cancer. The study supports current recommendations to conserve ovaries in premenopausal patients at low risk for ovarian cancer.
Experts recommend managing SARS-CoV-2 like other endemic respiratory viruses using Standard and Transmission-based Precautions. They also suggest reconsidering pandemic-era strategies such as asymptomatic testing and contact tracing in the endemic era.
A UFZ study shows that better communication and information can increase public support for nature-based flood prevention measures. People who feel connected to their community or informed about the measures are more likely to support them.
A new tool has been developed to measure customer aggression in the retail sector, which can lead to emotional exhaustion and job stress among employees. The scale identifies four types of aggressive behaviors, including being ignored or having fake negative reviews posted online.
Researchers used a novel machine-learning technique called causal forest, which found that treating individuals with high estimated benefits provided better population health outcomes than the traditional high-risk approach. This approach targets those with high blood pressure and could lead to more effective treatment strategies.
Research discovers that reduced levels of Hsp47 protein can prevent blood clots in humans, pigs, and bears, even when immobile for extended periods. The study's findings could lead to new medicines for people with inherited blood clotting disorders.
Researchers at the University of Gothenburg have developed a new epoxy resin monomer based on isosorbide, a substance produced from glucose, to reduce contact allergies. The new monomer is far less allergenic and not based on Bisphenol A (BPA), a known endocrine disruptor.
A new study published in The Lancet found that higher dose corticosteroids are associated with a 60% increased risk of death in hypoxic COVID-19 patients requiring only non-invasive oxygen therapy. The RECOVERY trial also identified an excess of pneumonia and hyperglycaemia in the higher-dose corticosteroid group.
A new study published in the American Journal of Psychiatry found a link between opioid prescribing patterns and suicide risk. The researchers analyzed data from 2009-2017 and discovered that regions with the greatest decrease in opioid prescriptions also experienced the greatest decline in suicide deaths. This suggests that policies a...
A study of over 43,000 adults found that parathyroidectomy has no estimated effect on long-term kidney function in older adults. However, early treatment may preserve kidney function in patients younger than 60 years old.
Researchers found that timed birth strategies, including induced labor and Cesarean deliveries, can reduce the risk of at-term preeclampsia by more than half. The study analyzed over 90,000 pregnancies and suggested that this approach has huge potential for global good in maternity care.
A randomized clinical trial found that anakinra did not prevent mechanical ventilation or reduce mortality risk in hospitalized patients with severe COVID-19 pneumonia. Future research is needed to assess anakinra in less severe cases.
A randomized controlled trial of High School FLASH, an LGBTQIA+ inclusive evidence-based sex education curriculum, found that the program reduced homophobic and transphobic beliefs among both LGBTQ and straight/cisgender students. The study also showed improved feelings of safety and connection to peers among LGBTQ students.
A study by Beth Israel Deaconess Medical Center found that climate change-related natural disasters have increased since 1980 and cost the US over $2 trillion in recovery costs. The analysis suggests that rising CO2 levels and temperatures will lead to more frequent and severe disasters, with exponentially increasing costs.
A study published by the University of Washington found that a community-based prevention system called Communities That Care (CTC) reduced handgun carrying among adolescents growing up in rural areas. By the 12th grade, adolescents in CTC communities were 24% less likely to report carrying a handgun than those in control communities.
The study reveals that a lack of community involvement and inadequate governance are major contributors to wildfire management in the Amazon region. Local stakeholders identified deficiencies in institutions, staff cuts, and underinvestment as significant vulnerabilities.
Adult survivors of childhood cancer have a four times higher risk of late mortality compared to the general population. Maintaining a healthy lifestyle can reduce this risk by 20%, according to a new study published in The Lancet.
Using image-based computational blood dynamics, researchers mimicked health conditions and investigated hemodynamic parameters to better understand how aneurysm size affects blood flow. They found that altered blood flow velocity distribution can lead to rupture, emphasizing the importance of early detection and treatment options.
A new study published in The European Heart Journal – Digital Health found that smart watch data can predict a higher risk of developing heart failure and irregular heart rhythms. Researchers used machine learning to analyze ECG recordings from wearable devices and identified extra beats as indicators of increased cardiovascular risk.
Researchers found that using monoclonal antibodies within two days of a COVID-19 diagnosis reduced the risk of hospitalization or death by 39% compared to those who did not receive treatment. This finding suggests that early treatment with monoclonal antibodies significantly reduced the severity of COVID-19.
Researchers analyzed 2,571 patients treated with monoclonal antibodies and found a 39% reduced risk of hospitalization or death compared to non-treated peers. The study also showed greater benefit in patients with immunocompromising conditions and those treated earlier during the pandemic.
Researchers successfully add purified curcumin to probiotic yogurt, preserving its dissolved form and enhancing its health properties. The study shows that the curcumin inhibits yeast, fungi, and bacteria growth while maintaining the recommended levels of beneficial lactic acid bacteria.
A University of Otago study finds that 40% of people diagnosed with HIV in Aotearoa were diagnosed late, highlighting the need for improved awareness and access to testing services. Early diagnosis is crucial for successful treatment and preventing transmission to sexual partners.
The REST-COAST Summer Workshop brought together experts from around the world to discuss innovative research and management strategies for coastal restoration. Key findings included the financing of restoration projects, nature-based solutions, and coupled modelling systems for risk reduction.
Researchers found that receipt of opioid use disorder-related telehealth services was associated with reduced risk for fatal drug overdoses. Additionally, medication from opioid treatment programs and buprenorphine in office-based settings also showed a protective effect.
A UCF research team, in partnership with the City of Orlando, aims to prevent falls among older adults through a low-cost, portable technology-based intervention. The project seeks to address public health disparities and support the development of affordable housing options.
A new study highlights the risks of cryptocurrency investors engaging in online gambling, with cryptocurrencies posing extreme price volatility. Cryptocasinos present a double danger, allowing gamblers to bet on sophisticated products using cryptocurrencies.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
Researchers found that fish in large schools are more willing to take risks and tune down their sensitivity to social cues, reducing the likelihood of responding to false alarms. This dynamic adjustment allows individuals to maintain control over their behavior, suggesting a potential evolutionary advantage in coping with misinformation.
The Tibetan Plateau's land surface darkening due to global warming affects regional and remote climates in Asia. The study predicts a 6.9% loss in glacier volume and increased monsoon precipitation over South Asia by the end of the century.
A new study by UC San Francisco found that taxes on sugary drinks lower the risk of gestational diabetes, unhealthy weight gain, and small-for-gestational-age babies. The study analyzed over 5 million pregnant women and found a significant reduction in these health risks.